Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2045) 2045
Publication (202) 202
Book Review (4) 4
Newspaper Article (4) 4
Book / eBook (2) 2
Book Chapter (2) 2
Conference Proceeding (2) 2
Trade Publication Article (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1288) 1288
humans (1203) 1203
male (1026) 1026
fluorine radioisotopes (904) 904
fluorine radioisotopes - pharmacokinetics (854) 854
tissue distribution (771) 771
radiopharmaceuticals - pharmacokinetics (732) 732
index medicus (730) 730
female (713) 713
mice (628) 628
pet (554) 554
positron-emission tomography (553) 553
rats (537) 537
positron emission tomography (476) 476
radiology, nuclear medicine & medical imaging (470) 470
positron-emission tomography - methods (460) 460
brain - metabolism (417) 417
tomography, emission-computed (398) 398
brain - diagnostic imaging (388) 388
middle aged (388) 388
adult (336) 336
positron-emission-tomography (303) 303
fluorine radioisotopes - chemistry (292) 292
aged (280) 280
radiopharmaceuticals - chemical synthesis (274) 274
rats, sprague-dawley (224) 224
brain (213) 213
cell line, tumor (202) 202
neurosciences (191) 191
fluorodeoxyglucose f18 - pharmacokinetics (188) 188
radiopharmaceuticals - chemistry (176) 176
fluorodeoxyglucose f18 (170) 170
oncology (167) 167
pet imaging (167) 167
ligands (162) 162
in-vivo (156) 156
article (154) 154
isotope labeling (153) 153
deoxyglucose - analogs & derivatives (149) 149
deoxyglucose - pharmacokinetics (148) 148
kinetics (144) 144
tomography (141) 141
autoradiography (140) 140
cancer (135) 135
radionuclide imaging (135) 135
chemistry, medicinal (133) 133
metabolism (129) 129
fluorine-18 (126) 126
binding (123) 123
mice, nude (121) 121
radiopharmaceuticals (120) 120
isotope labeling - methods (113) 113
tomography, x-ray computed (113) 113
time factors (110) 110
tomography, emission-computed - methods (109) 109
sensitivity and specificity (106) 106
dihydroxyphenylalanine - analogs & derivatives (105) 105
dihydroxyphenylalanine - pharmacokinetics (104) 104
metabolic clearance rate (103) 103
radioisotopes (103) 103
tumors (101) 101
macaca mulatta (98) 98
radiology (95) 95
magnetic resonance imaging (94) 94
organ specificity (93) 93
structure-activity relationship (92) 92
rats, wistar (91) 91
reproducibility of results (91) 91
medicine & public health (90) 90
nuclear medicine (89) 89
fluorine isotopes (88) 88
pharmacology & pharmacy (88) 88
radiochemistry (88) 88
chromatography, high pressure liquid (86) 86
neoplasms - diagnostic imaging (85) 85
medical imaging (83) 83
pharmacokinetics (83) 83
imaging / radiology (81) 81
biochemistry & molecular biology (80) 80
mice, inbred balb c (80) 80
models, biological (80) 80
aged, 80 and over (78) 78
myocardium - metabolism (77) 77
molecular structure (76) 76
carbon radioisotopes (75) 75
neoplasm transplantation (75) 75
neuroimaging (74) 74
biodistribution (72) 72
heart - diagnostic imaging (71) 71
parkinsons-disease (71) 71
pyridines - pharmacokinetics (71) 71
chemistry, organic (70) 70
expression (68) 68
f-18 (68) 68
medicine (67) 67
brain neoplasms - diagnostic imaging (66) 66
clinical neurology (66) 66
biological transport (64) 64
liver - metabolism (63) 63
positron emission (63) 63
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1998) 1998
German (26) 26
Spanish (21) 21
French (19) 19
Japanese (17) 17
Chinese (2) 2
Russian (2) 2
Italian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Comparison study of [ 18F]FAl-NOTA-PRGD2, [ 18F] FPPRGD2, and [ 68Ga]Ga-NOTA-PRGD2 for PET imaging of u87mg tumors in mice
by Lang, Lixin and Li, Weihua and Guo, Ning and Ma, Ying and Zhu, Lei and Kiesewetter, Dale O and Shen, Baozhong and Niu, Gang and Chen, Xiaoyuan
Bioconjugate Chemistry, ISSN 1043-1802, 12/2011, Volume 22, Issue 12, pp. 2415 - 2422
[(18)F]FPPRGD2, an F-18 labeled dimeric cyclic RGDyK peptide, has favorable properties for PET imaging of angiogenesis by targeting the α(v)β(3) integrin... 
Humans | Oligopeptides - pharmacokinetics | Neoplasms - diagnosis | Gallium Radioisotopes - chemistry | Positron-Emission Tomography - methods | Animals | Fluorine Radioisotopes - pharmacokinetics | Heterocyclic Compounds - chemistry | Cell Line, Tumor | Gallium Radioisotopes - pharmacokinetics | Heterocyclic Compounds - pharmacokinetics | Mice | Fluorine Radioisotopes - chemistry | Oligopeptides - chemistry | Ga-68 | Arg-Gly-Asp (RGD) peptide | integrin αvβ3 | fluorine-aluminum complex | positron emission tomography (PET) | F-18
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36: Test–retest reproducibility and head-to-head comparison with the antagonist [18F]altanserin
by Ettrup, Anders and Svarer, Claus and McMahon, Brenda and da Cunha-Bang, Sofi and Lehel, Szabolcs and Møller, Kirsten and Dyssegaard, Agnete and Ganz, Melanie and Beliveau, Vincent and Jørgensen, Louise Møller and Gillings, Nic and Knudsen, Gitte Moos
NeuroImage, ISSN 1053-8119, 04/2016, Volume 130, pp. 167 - 174
[ C]Cimbi-36 is a recently developed serotonin 2A (5-HT ) receptor agonist positron emission tomography (PET) radioligand that has been successfully applied... 
Neuroimaging | Agonist | 5-HT | Positron emission tomography | Radiotracer evaluation | Test–retest variability | Test-retest variability | SURFACE-BASED ANALYSIS | SYSTEM | LOCALIZATION | BOLUS/INFUSION APPROACH | QUANTIFICATION | BEHAVIOR | 5-HT2A RECEPTOR | RATS | NEUROSCIENCES | POSITRON-EMISSION-TOMOGRAPHY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET RADIOLIGAND | Serotonin 5-HT2 Receptor Agonists - pharmacokinetics | Humans | Ketanserin - analogs & derivatives | Male | Benzylamines - metabolism | Brain - metabolism | Young Adult | Radiopharmaceuticals - metabolism | Fluorine Radioisotopes - pharmacokinetics | Phenethylamines - pharmacokinetics | Female | Serotonin 5-HT2 Receptor Agonists - metabolism | Neuroimaging - methods | Reproducibility of Results | Radiopharmaceuticals - pharmacokinetics | Carbon Radioisotopes - pharmacokinetics | Phenethylamines - metabolism | Positron-Emission Tomography - methods | Serotonin 5-HT2 Receptor Antagonists - pharmacokinetics | Ketanserin - metabolism | Ketanserin - pharmacokinetics | Serotonin 5-HT2 Receptor Antagonists - metabolism | Fluorine Radioisotopes - metabolism | Carbon Radioisotopes - metabolism | Benzylamines - pharmacokinetics | Phenols | Brain | Serotonin | Analysis | Choroid plexus | Medical imaging | Lysergic acid diethylamide--LSD | Cortex | Radioisotopes | Serotonin S2 receptors | Tomography | Receptor density | Agonists | Hippocampus | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography
by Gobbi, Luca C and Knust, Henner and Körner, Matthias and Honer, Michael and Czech, Christian and Belli, Sara and Muri, Dieter and Edelmann, Martin R and Hartung, Thomas and Erbsmehl, Isabella and Grall-Ulsemer, Sandra and Koblet, Andreas and Rueher, Marianne and Steiner, Sandra and Ravert, Hayden T and Mathews, William B and Holt, Daniel P and Kuwabara, Hiroto and Valentine, Heather and Dannals, Robert F and Wong, Dean F and Borroni, Edilio
Journal of Medicinal Chemistry, ISSN 0022-2623, 2017, Volume 60, Issue 17, pp. 7350 - 7370
Aggregates of tau and beta amyloid (A beta) plaques constitute the histopathological hallmarks of Alzheimer's disease and are prominent targets for novel... 
NEUROFIBRILLARY TANGLES | NONSPECIFIC-BINDING | PET RADIOLIGANDS | CHEMISTRY, MEDICINAL | ASSAY | QUANTIFICATION | DRUG DISCOVERY | MOUSE MODEL | CENTRAL-NERVOUS-SYSTEM | PATHOLOGY | LIGAND | Carbon Radioisotopes - pharmacokinetics | Humans | Male | Positron-Emission Tomography - methods | Pyrimidines - chemistry | Papio | Carbon Radioisotopes - chemistry | Animals | Fluorine Radioisotopes - pharmacokinetics | Protein Aggregation, Pathological - diagnostic imaging | Pyrimidines - pharmacokinetics | Mice | tau Proteins - analysis | Alzheimer Disease - diagnostic imaging | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo
by Venneti, Sriram and Dunphy, Mark P and Zhang, Hanwen and Pitter, Kenneth L and Zanzonico, Patrick and Campos, Carl and Carlin, Sean D and La Rocca, Gaspare and Lyashchenko, Serge and Ploessl, Karl and Rohle, Daniel and Omuro, Antonio M and Cross, Justin R and Brennan, Cameron W and Weber, Wolfgang A and Holland, Eric C and Mellinghoff, Ingo K and Kung, Hank F and Lewis, Jason S and Thompson, Craig B
Science Translational Medicine, ISSN 1946-6234, 02/2015, Volume 7, Issue 274, pp. 274ra17 - 274ra17
Glucose and glutamine are the two principal nutrients that cancer cells use to proliferate and survive. Many cancers show altered glucose metabolism, which... 
MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | GROWTH | TUMOR METABOLISM | BLOOD-BRAIN-BARRIER | X(C)(-) TRANSPORTER ACTIVITY | REVEALS | CELL BIOLOGY | Fluorine Radioisotopes - pharmacokinetics | Glioma - pathology | Humans | Brain Neoplasms - pathology | Fluorine Radioisotopes - metabolism | Glutamine - metabolism | Positron-Emission Tomography | Glutamine - pharmacokinetics | Brain Neoplasms - metabolism | Disease Progression | Blood-Brain Barrier | Glioma - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text The role of radiotracer imaging in Parkinson disease
by Ravina, B and Eidelberg, D and Ahlskog, J.E and Albin, R.L and Brooks, D.J and Carbon, M and Dhawan, V and Feigin, A and Fahn, S and Guttman, M and Gwinn-Hardy, K and McFarland, H and Innis, R and Katz, R.G and Kieburtz, K and Kish, S.J and Lange, N and Langston, J.W and Marek, K and Morin, L and Moy, C and Murphy, D and Oertel, W.H and Oliver, G and Palesch, Y and Powers, W and Seibyl, J and Sethi, K.D and Shults, C.W and Sheehy, P and Stoessl, A.J and Holloway, R
Neurology, ISSN 0028-3878, 01/2005, Volume 64, Issue 2, pp. 208 - 215
Radiotracer imaging (RTI) of the nigrostriatal dopaminergic system is a widely used but controversial biomarker in Parkinson disease (PD). Here the authors... 
SURROGATE END-POINTS | DIFFERENTIAL-DIAGNOSIS | POSITRON-EMISSION-TOMOGRAPHY | STRIATAL DOPAMINE TRANSPORTER | INITIAL TREATMENT | RANDOMIZED CONTROLLED-TRIAL | QUALITY-OF-LIFE | SUBSTANTIA-NIGRA | F-18 FLUORODEOXYGLUCOSE | CLINICAL NEUROLOGY | LEVODOPA | Parkinson Disease - therapy | Fluorodeoxyglucose F18 - pharmacokinetics | Prognosis | Humans | Dihydroxyphenylalanine - analogs & derivatives | Tomography, Emission-Computed, Single-Photon | Positron-Emission Tomography | Dihydroxyphenylalanine - pharmacokinetics | Substantia Nigra - metabolism | Corpus Striatum - metabolism | Tetrabenazine - pharmacokinetics | Fluorine Radioisotopes - pharmacokinetics | Biotransformation | Dopamine - metabolism | Tetrabenazine - analogs & derivatives | Parkinson Disease - diagnostic imaging | Radiopharmaceuticals - pharmacokinetics | Neurons - chemistry | Receptors, Dopamine - metabolism | Carbon Radioisotopes - pharmacokinetics | Cocaine - pharmacokinetics | Iodine Radioisotopes - pharmacokinetics | Cocaine - analogs & derivatives | Forecasting | Neurons - diagnostic imaging | Substantia Nigra - diagnostic imaging | Biomarkers | Parkinson Disease - diagnosis | Clinical Trials as Topic - methods | Corpus Striatum - diagnostic imaging | Blood-Brain Barrier
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text 18F stilbenes and styrylpyridines for PET imaging of Aβ plaques in Alzheimer's disease: A miniperspective
by Kung, Hank F and Choi, Seok Rye and Qu, Wenchao and Zhang, Wei and Skovronsky, Daniel
Journal of Medicinal Chemistry, ISSN 0022-2623, 2010, Volume 53, Issue 3, pp. 933 - 941
Brain - diagnostic imaging | Humans | Styrenes - pharmacokinetics | Pyridines - pharmacokinetics | Positron-Emission Tomography | Brain - metabolism | Tissue Distribution | Fluorine Radioisotopes - pharmacokinetics | Plaque, Amyloid - diagnostic imaging | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Stilbenes - pharmacokinetics | Plaque, Amyloid - metabolism | Alzheimer Disease - diagnostic imaging
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Synthesis and preliminary PET imaging of 11 C and 18 F isotopologues of the ROS1/ALK inhibitor lorlatinib
by Collier, Thomas Lee and Normandin, Marc D and Stephenson, Nickeisha A and Livni, Eli and Liang, Steven H and Wooten, Dustin W and Esfahani, Shadi A and Stabin, Michael G and Mahmood, Umar and Chen, Jianqing and Wang, Wei and Maresca, Kevin and Waterhouse, Rikki N and El Fakhri, Georges and Richardson, Paul and Vasdev, Neil
Nature Communications, 06/2017, Volume 8, p. 15761
Lorlatinib (PF-06463922) is a next-generation small-molecule inhibitor of the orphan receptor tyrosine kinase c-ros oncogene 1 (ROS1), which has a kinase... 
Proto-Oncogene Proteins - antagonists & inhibitors | Chemistry Techniques, Synthetic | Carbon Radioisotopes - pharmacokinetics | Humans | Contrast Media - pharmacokinetics | Male | Macaca mulatta | Positron-Emission Tomography - methods | Lactams, Macrocyclic - pharmacology | Contrast Media - chemical synthesis | Tissue Distribution | Xenograft Model Antitumor Assays | Carbon Radioisotopes - chemistry | Isotope Labeling - methods | Lactams, Macrocyclic - chemistry | Animals | Lactams, Macrocyclic - pharmacokinetics | Mice | Fluorine Radioisotopes - chemistry | Anaplastic Lymphoma Kinase - antagonists & inhibitors | Fluorine Radioisotopes - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition
by Gottesman, Rebecca F and Schneider, Andrea L. C and Zhou, Yun and Coresh, Josef and Green, Edward and Gupta, Naresh and Knopman, David S and Mintz, Akiva and Rahmim, Arman and Sharrett, A. Richey and Wagenknecht, Lynne E and Wong, Dean F and Mosley, Thomas H
JAMA, ISSN 0098-7484, 04/2017, Volume 317, Issue 14, pp. 1443 - 1450
IMPORTANCE: Midlife vascular risk factors have been associated with late-life dementia. Whether these risk factors directly contribute to brain amyloid... 
DIABETES-MELLITUS | UNITED-STATES | F 18 | MEDICINE, GENERAL & INTERNAL | DEMENTIA | STROKE RISK | ALZHEIMERS-DISEASE | IN-VIVO | COMMUNITIES | CORONARY-HEART-DISEASE | ATHEROSCLEROSIS RISK | Smoking - adverse effects | Brain - diagnostic imaging | Diabetes Complications | Prospective Studies | Age Factors | Follow-Up Studies | Humans | Middle Aged | Male | Ethylene Glycols - pharmacokinetics | Brain - metabolism | Fluorine Radioisotopes - pharmacokinetics | Amyloid - metabolism | Time Factors | Aged, 80 and over | Female | Odds Ratio | Body Mass Index | Risk Factors | European Continental Ancestry Group | Aniline Compounds - pharmacokinetics | Positron-Emission Tomography - methods | Dementia - etiology | Apolipoproteins E - genetics | Alleles | Hypertension - complications | Hypercholesterolemia - complications | Aged | African Continental Ancestry Group | Alzheimer Disease - genetics | Middle age | Risk factors (Health) | Demographic aspects | Analysis | Development and progression | Amyloidosis | Glycoproteins | Research | Health aspects | Alzheimer's disease | Risk factors | Vein & artery diseases | Atherosclerosis | Dementia | epidemiology | dementia | amyloid | hypertension
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Coronary arterial 18F-sodium fluoride uptake: A novel marker of plaque biology
by Dweck, Marc R and Chow, Marcus W.L and Joshi, Nikhil V and Williams, Michelle C and Jones, Charlotte and Fletcher, Alison M and Richardson, Hamish and White, Audrey and McKillop, Graham and Van Beek, Edwin J.R and Boon, Nicholas A and Rudd, James H.F and Newby, David E
Journal of the American College of Cardiology, ISSN 0735-1097, 04/2012, Volume 59, Issue 17, pp. 1539 - 1548
Objectives: With combined positron emission tomography and computed tomography (CT), we investigated coronary arterial uptake of 18F-sodium fluoride (18F-NaF)... 
acute coronary syndrome | calcification | positron emission tomography | inflammation | risk prediction | HIGH-FAT | CARDIAC & CARDIOVASCULAR SYSTEMS | LOW-CARBOHYDRATE | AMERICAN-HEART-ASSOCIATION | COMPUTED-TOMOGRAPHY | POSITRON-EMISSION-TOMOGRAPHY | MYOCARDIAL F-18-FDG UPTAKE | ATHEROSCLEROTIC PLAQUE | VULNERABLE PLAQUE | F-18-FLUORIDE PET | Coronary Vessels - diagnostic imaging | Severity of Illness Index | Fluorodeoxyglucose F18 - pharmacokinetics | Coronary Vessels - pathology | Reproducibility of Results | Prospective Studies | Risk Assessment | Humans | Middle Aged | Biomarkers - analysis | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Coronary Artery Disease - diagnostic imaging | Fluorine Radioisotopes - pharmacokinetics | Sodium Fluoride - pharmacokinetics | Coronary Angiography - methods | Sensitivity and Specificity | Female | Aged | Aorta, Thoracic - diagnostic imaging | Aorta, Thoracic - pathology | Observer Variation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: A validation study for the theranostic approach using [ 18 F]-L-FBPA positron emission tomography in boron neutron capture therapy
by Watanabe, Tsubasa and Hattori, Yoshihide and Ohta, Youichiro and Ishimura, Miki and Nakagawa, Yosuke and Sanada, Yu and Tanaka, Hiroki and Fukutani, Satoshi and Masunaga, Shin-ichiro and Hiraoka, Masahiro and Ono, Koji and Suzuki, Minoru and Kirihata, Mitsunori
BMC Cancer, ISSN 1471-2407, 11/2016, Volume 16, Issue 1, p. 859
Background: Boron neutron capture therapy (BNCT) is a cellular-level particle radiation therapy that combines the selective delivery of boron compounds to... 
F]-L-FBPA | Boron concentration | [ | FBPA | L-BPA | Boron neutron capture therapy | BORONOPHENYLALANINE | BRAIN-TUMOR | ONCOLOGY | [F-18]-L-FBPA | TISSUE | COMPOUND | IMPROVEMENT | 4-BORONO-2-FLUORO-D,L-PHENYLALANINE | Tissue Distribution | Animals | Fluorine Radioisotopes - pharmacokinetics | Fluorine Radioisotopes - administration & dosage | Boron Neutron Capture Therapy | Female | Neoplasms - radiotherapy | Mice | Positron-Emission Tomography | Fluorine Radioisotopes - chemistry | Neoplasms - diagnostic imaging | Disease Models, Animal | Usage | PET imaging | Boron-neutron capture therapy | Analysis | Radiation | Pharmacokinetics | Health aspects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text A Superfluorinated Molecular Probe for Highly Sensitive in Vivo(19)F-MRI
by Tirotta, I and Mastropietro, A and Cordiglieri, C and Gazzera, L and Baggi, F and Baselli, G and Bruzzone, MG and Zucca, I and Cavallo, G and Terraneo, G and Bombelli, FB and Metrangolo, P and Resnati, G
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 06/2014, Volume 136, Issue 24, pp. 8524 - 8527
F-19-MRI offers unique opportunities to image diseases and track cells and therapeutic agents in vivo, Herein we report a superfluorinated molecular probe,... 
CELLS | CHEMISTRY, MULTIDISCIPLINARY | FLUOROUS SYNTHESIS | Rats, Inbred Lew | Models, Molecular | Rats | Hydrocarbons, Fluorinated - chemistry | Tissue Distribution | Hydrocarbons, Fluorinated - pharmacokinetics | Magnetic Resonance Imaging | Animals | Fluorine Radioisotopes - pharmacokinetics | Hydrocarbons, Fluorinated - administration & dosage | Fluorine Radioisotopes - administration & dosage | Injections, Subcutaneous | Molecular Structure | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Molecular mechanisms of bone 18F-NaF deposition
by Czernin, Johannes and Satyamurthy, Nagichettiar and Schiepers, Christiaan
Journal of Nuclear Medicine, ISSN 0161-5505, 12/2010, Volume 51, Issue 12, pp. 1826 - 1829
There is renewed interest in (18)F-NaF bone imaging with PET or PET/CT. The current brief discussion focuses on the molecular mechanisms of (18)F-NaF... 
F-NaF | Bone fluoride deposition | PET/CT | Radiopharmaceuticals - pharmacokinetics | Bone Neoplasms - diagnostic imaging | Humans | Rats | Positron-Emission Tomography | Bone Diseases - diagnostic imaging | Radiopharmaceuticals - chemical synthesis | Cyclotrons | Sodium Fluoride - chemical synthesis | Animals | Fluorine Radioisotopes - pharmacokinetics | Sodium Fluoride - pharmacokinetics | Models, Biological | Bone and Bones - diagnostic imaging | Bone and Bones - metabolism | Drug Compounding | Mice | bone fluoride deposition | 18F-NaF | PET
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Correlation between Ki-67 immunohistochemistry and 18F-Fluorothymidine uptake in patients with cancer: A systematic review and meta-analysis
by Chalkidou, A and Landau, D.B and Odell, E.W and Cornelius, V.R and O’Doherty, M.J and Marsden, P.K
European Journal of Cancer, ISSN 0959-8049, 2012, Volume 48, Issue 18, pp. 3499 - 3513
Abstract Background Positron emission tomography (PET) imaging using the radiotracer 18F-Fluorothymidine (FLT) has been proposed as an imaging biomarker of... 
Hematology, Oncology and Palliative Medicine | Ki-67 | Systematic review | Fluorothymidine | QUADAS | PET | Meta-analysis | PRIMARY HEAD | BRAIN-TUMORS | BREAST-CANCER | HETEROGENEITY | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | IN-VIVO | F-18-FLT PET | FLT-PET | IMAGING PROLIFERATION | CELLULAR PROLIFERATION | Immunohistochemistry | Radiopharmaceuticals - pharmacokinetics | Clinical Trials as Topic - statistics & numerical data | Bias | Humans | Male | Positron-Emission Tomography | Neoplasms - diagnostic imaging | Dideoxynucleosides - pharmacokinetics | Tissue Distribution | Fluorine Radioisotopes - pharmacokinetics | Ki-67 Antigen - analysis | Biopsy | Cell Division | Biomarkers | Female | Surveys and Questionnaires | Antigens, Neoplasm - analysis | Neoplasms - pathology | Research Design | Care and treatment | Cancer patients | PET imaging | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on in Vitro SSTR Binding and in Vivo Pharmacokinetics
by Litau, S and Niedermoser, S and Vogler, N and Roscher, M and Schirrmacher, R and Fricker, G and Wängler, B and Wängler, C
Bioconjugate Chemistry, ISSN 1043-1802, 12/2015, Volume 26, Issue 12, pp. 2350 - 2359
The Silicon-Fluoride-Acceptor (SiFA)-F-18-labeling strategy has been shown before to enable the straightforward and efficient F-18-labeling of complex... 
ANALOGS | BUILDING-BLOCKS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | RADIOLABELED PEPTIDES | CHEMISTRY, ORGANIC | SOMATOSTATIN RECEPTORS | BIODISTRIBUTION | CHEMISTRY, MULTIDISCIPLINARY | POSITRON-EMISSION-TOMOGRAPHY | FLUORIDE-ACCEPTOR | THERAPY | RENAL UPTAKE | PRECLINICAL EVALUATION | Neoplasms - metabolism | Cell Line | Fluorides - pharmacokinetics | Silicon - metabolism | Fluorides - metabolism | Humans | Silicon - pharmacokinetics | Models, Molecular | Neoplasms - diagnosis | Positron-Emission Tomography - methods | Neoplasms - diagnostic imaging | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Peptides, Cyclic - pharmacokinetics | Fluorides - chemistry | Animals | Fluorine Radioisotopes - pharmacokinetics | Mice, Nude | Cell Line, Tumor | Fluorine Radioisotopes - metabolism | Receptors, Somatostatin - metabolism | Fluorine Radioisotopes - chemistry | Silicon - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text (R)- and (S)- 18 F-labeled 2-arylbenzofurans with improved pharmacokinetics as β-amyloid imaging probes
by Song, Jia and Zhang, Xiaoyang and Zhao, Yunling and Yang, Hui and Zhang, Jinming and Zhang, Xiaojun and Dai, Jiapei and Cui, Mengchao
European journal of medicinal chemistry, ISSN 0223-5234, 07/2017, Volume 134, pp. 271 - 280
A new class of optical isomers of 2-arylbenzofuran derivatives were synthesized and evaluated as potential β-amyloid plaques imaging agents. Both lipophilicity... 
Brain - diagnostic imaging | Humans | Mice, Inbred C57BL | Male | Positron-Emission Tomography - methods | Mice, Inbred ICR | Benzofurans - chemistry | Benzofurans - pharmacokinetics | Tissue Distribution | Animals | Fluorine Radioisotopes - pharmacokinetics | Plaque, Amyloid - diagnostic imaging | Amyloid beta-Peptides - analysis | Mice | Alzheimer Disease - diagnostic imaging | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Predicting Treatment Response of Malignant Gliomas to Bevacizumab and Irinotecan by Imaging Proliferation With [18F] Fluorothymidine Positron Emission Tomography: A Pilot Study
by Wei Chen and Sibylle Delaloye and Daniel H.S. Silverman and Cheri Geist and Johannes Czernin and James Sayre and Nagichettiar Satyamurthy and Whitney Pope and Albert Lai and Michael E. Phelps and Timothy Cloughesy
Journal of Clinical Oncology, ISSN 0732-183X, 10/2007, Volume 25, Issue 30, pp. 4714 - 4721
Purpose Evaluation of treatment effects in malignant brain tumors is challenging because of the lack of reliable response predictors of tumor response. This... 
PRIMARY BRAIN-TUMORS | LUNG-CANCER | RECTAL-CANCER | ONCOLOGY | GLIOBLASTOMA-MULTIFORME | COLORECTAL-CANCER | IN-VIVO | RADIATION NECROSIS | DRUG DEVELOPMENT | PHASE-II | ENDOTHELIAL GROWTH-FACTOR | Cell Proliferation | Prognosis | Prospective Studies | Brain Neoplasms - diagnostic imaging | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Positron-Emission Tomography | Bevacizumab | Antibodies, Monoclonal, Humanized | Fluorine Radioisotopes - pharmacokinetics | Adult | Camptothecin - administration & dosage | Female | Camptothecin - analogs & derivatives | Thymidine - pharmacokinetics | Radiopharmaceuticals - pharmacokinetics | Survival Rate | Brain Neoplasms - drug therapy | Radiography | Pilot Projects | Glioma - diagnostic imaging | Antibodies, Monoclonal - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Neoplasm Staging | Glioma - drug therapy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text Pharmacokinetics of [ 18F]flutemetamol in wild-type rodents and its binding to beta amyloid deposits in a mouse model of Alzheimer's disease
by Snellman, Anniina and Rokka, Johanna and Lopez-Picon, Francisco R and Eskola, Olli and Wilson, Ian and Farrar, Gill and Scheinin, Mika and Solin, Olof and Rinne, Juha O and Haaparanta-Solin, Merja
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 11/2012, Volume 39, Issue 11, pp. 1784 - 1795
The aim of this study was to investigate the potential of [F-18]flutemetamol as a preclinical PET tracer for imaging beta-amyloid (A beta) deposition by... 
C]PIB | F] Flutemetamol | Alzheimer's disease | Positron emission tomography | RADIATION-DOSIMETRY | [F-18]Flutemetamol | RADIOLIGAND | [C-11]PIB | COGNITIVE IMPAIRMENT | PLAQUES | PITTSBURGH COMPOUND-B | POSITRON-EMISSION-TOMOGRAPHY | TRANSGENIC RAT MODEL | F-18-FLUTEMETAMOL | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | BRAIN | Radiopharmaceuticals - pharmacokinetics | Mice, Inbred C57BL | Rats | Mice, Transgenic | Positron-Emission Tomography | Aniline Compounds - pharmacokinetics | Benzothiazoles - pharmacokinetics | Rats, Sprague-Dawley | Thiazoles - pharmacokinetics | Tissue Distribution | Animals | Fluorine Radioisotopes - pharmacokinetics | Amyloid beta-Peptides - metabolism | Mice | Alzheimer Disease - diagnostic imaging | Alzheimer Disease - genetics | Disease Models, Animal | Pharmacology | Medical imaging | Alzheimers disease | Rodents
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text Glioma Proliferation as Assessed by 3‘-Fluoro-3’-Deoxy-l-Thymidine Positron Emission Tomography in Patients with Newly Diagnosed High-Grade Glioma
by Roland Ullrich and Heiko Backes and Hongfeng Li and Lutz Kracht and Hrvoje Miletic and Kristina Kesper and Bernd Neumaier and Wolf-Dieter Heiss and Klaus Wienhard and Andreas H. Jacobs
Clinical Cancer Research, ISSN 1078-0432, 04/2008, Volume 14, Issue 7, pp. 2049 - 2055
Purpose: The aim of this study was to investigate the relationship between the in vivo derived kinetic parameters of 3′-deoxy-3′- 18 F-fluorothymidine ( 18... 
glioma | proliferation | FLT | kinetic modeling | THYMIDINE | METABOLISM | ONCOLOGY | IN-VIVO | KINETIC-ANALYSIS | VALIDATION | LUNG-TUMORS | IMAGING PROLIFERATION | PET | BRAIN-TUMORS | Immunohistochemistry | Cell Proliferation | Radiopharmaceuticals - pharmacokinetics | Brain Neoplasms - diagnostic imaging | Carbon Radioisotopes - pharmacokinetics | Humans | Middle Aged | Brain Neoplasms - pathology | Ki-67 Antigen - metabolism | Male | Positron-Emission Tomography | Dideoxynucleosides - pharmacokinetics | Tissue Distribution | Magnetic Resonance Imaging | Fluorine Radioisotopes - pharmacokinetics | Glioma - diagnostic imaging | Glioma - pathology | Methionine - pharmacokinetics | Adult | Female | Aged
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights