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1. Full Text Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
by Cypess, Aaron M and Weiner, Lauren S and Roberts-Toler, Carla and Elía, Elisa Franquet and Kessler, Skyler H and Kahn, Peter A and English, Jeffrey and Chatman, Kelly and Trauger, Sunia A and Doria, Alessandro and Kolodny, Gerald M
Cell Metabolism, ISSN 1550-4131, 01/2015, Volume 21, Issue 1, pp. 33 - 38
Increasing energy expenditure through activation of endogenous brown adipose tissue (BAT) is a potential approach to treat obesity and diabetes. The class of... 
Obesity - drug therapy | Humans | Fluorodeoxyglucose F18 - metabolism | Adrenergic Agonists - pharmacology | Adrenergic Agonists - therapeutic use | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Acetanilides - analysis | Basal Metabolism - drug effects | Chromatography, High Pressure Liquid | Thiazoles - therapeutic use | Young Adult | Tandem Mass Spectrometry | Receptors, Adrenergic, beta-3 - chemistry | Acetanilides - therapeutic use | Adrenergic Agonists - analysis | Acetanilides - pharmacology | Fluorodeoxyglucose F18 - chemistry | Receptors, Adrenergic, beta-3 - metabolism | Thiazoles - analysis | Glucose - metabolism | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Thiazoles - pharmacology
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2. Full Text The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis
by Leijenaar, Ralph T. H and Nalbantov, Georgi and Carvalho, Sara and van Elmpt, Wouter J. C and Troost, Esther G. C and Boellaard, Ronald and Aerts, Hugo J. W. L and Gillies, Robert J and Lambin, Philippe
Scientific Reports, ISSN 2045-2322, 08/2015, Volume 5, Issue 1, p. 11075
FDG-PET-derived textural features describing intra-tumor heterogeneity are increasingly investigated as imaging biomarkers. As part of the process of... 
CELL LUNG-CANCER | F-18-FDG PET | UPTAKE HETEROGENEITY | IMAGES | STAGE | QUANTIFICATION | MULTIDISCIPLINARY SCIENCES | RESPONSE ASSESSMENT | RADIOTHERAPY | CARCINOMA | FEATURES | Lung Neoplasms - drug therapy | Humans | Lung Neoplasms - metabolism | Fluorodeoxyglucose F18 - metabolism | Lung Neoplasms - radiotherapy | Fluorodeoxyglucose F18 - chemistry | Tomography, X-Ray Computed | Positron-Emission Tomography | Feasibility Studies | Radiopharmaceuticals - metabolism | Image Processing, Computer-Assisted | Biomarkers, Tumor - metabolism | Radiopharmaceuticals - therapeutic use | Lung cancer | Radiation therapy
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3. Full Text Linker structure-activity relationships in fluorodeoxyglucose chlorambucil conjugates for tumor-targeted chemotherapy
by El Hilali, Mostafa and Reux, Bastien and Debiton, Eric and Leal, Fernand and Galmier, Marie-Josephe and Vivier, Magali and Chezal, Jean-Michel and Miot-Noirault, Elisabeth and Coudert, Pascal and Weber, Valérie
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 10/2017, Volume 25, Issue 20, pp. 5692 - 5708
Pharmacomodulation of the linker tethered the FDG tumor-seeking group and the alkylating -mustard leads to compound , identified as the most active FDG-CLB... 
Chlorambucil | 2-Fluoro-2-deoxy-d-glucose derivatives | In vitro cytotoxicity | Tumor-targeting drug delivery | 2-Fluoro-2-deoxy-D-glucose derivatives | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | DRUG-RELEASE | GLUCOSE TRANSPORTERS | CANCER-THERAPY | DELIVERY | PACLITAXEL | IN-VITRO | METABOLISM | ALKYLATING-AGENTS | DERIVATIVES | EXPRESSION | Chlorambucil - chemistry | Cell Line | Cell Survival | Humans | Antineoplastic Agents, Alkylating - pharmacology | Fluorodeoxyglucose F18 - chemistry | Structure-Activity Relationship | Fluorodeoxyglucose F18 - toxicity | Chlorambucil - pharmacology | Antigens, Neoplasm - chemistry | Drug Delivery Systems | Fluorodeoxyglucose F18 - chemical synthesis | Antineoplastic Agents, Alkylating - toxicity | Cell Line, Tumor | Chlorambucil - chemical synthesis | Inhibitory Concentration 50 | Cell Proliferation - drug effects | Fluorodeoxyglucose F18 - pharmacology | Molecular Structure | Antineoplastic Agents, Alkylating - chemistry | Antimitotic agents | Chemotherapy | Antineoplastic agents | Cancer | Tumors | Drugs | Glucose metabolism | Drug delivery systems | Glucose | Chemical synthesis | Dextrose | Vehicles | Index Medicus | Medicinal Chemistry | Organic chemistry | Chemical Sciences
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4. Full Text Synthesis and evaluation of an N-[18F]fluorodeoxyglycosyl amino acid for PET imaging of tumor metabolism
by Wu, Zhifang and Ma, Jingxin and Brownell, Anna-liisa and Wang, Hongliang and Li, Sijin and Li, Chaomin and Meng, Xiaxia and Yuan, Ling and Liu, Haiyan and Xie, Jun
Nuclear Medicine and Biology, ISSN 0969-8051, 11/2018, Volume 66, pp. 40 - 48
The limitations of [ F]fluorodeoxyglucose ([ F]FDG), including producing false-positive or -negative results, low image contrast in brain tumor diagnosis and... 
PET probe | PET/CT imaging | N-[18F]fluorodeoxyglycosyl amino acid | Radiosynthesis | F]fluorodeoxyglycosyl amino acid | FDG-PET | N-[F-18]fluorodeogglycosyl amino acid | BIOLOGICAL EVALUATION | F-18-FDG | TRACERS | DIFFERENTIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PROBES | Fluorodeoxyglucose F18 - pharmacokinetics | Chemistry Techniques, Synthetic | Drug Stability | Humans | Fluorodeoxyglucose F18 - metabolism | Fluorodeoxyglucose F18 - chemistry | Fluorodeoxyglucose F18 - chemical synthesis | Hep G2 Cells | Tissue Distribution | Animals | Phenylalanine - chemistry | Radiochemistry | Mice | Positron Emission Tomography Computed Tomography - methods | Physiological aspects | Pets | Amino acids | PET imaging | Brain tumors | High performance liquid chromatography
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5. Full Text A novel method for direct site-specific radiolabeling of peptides Using [ 18F]FDG
by Namavari, Mohammad and Cheng, Zhen and Zhang, Rong and De Abhijit, Abhijit and Levi, Jelena and Hoerner, Joshua K and Yaghoubi, Shahriar S and Syud, Faisal A and Gambhir, Sanjiv S
Bioconjugate Chemistry, ISSN 1043-1802, 03/2009, Volume 20, Issue 3, pp. 432 - 436
We have used the well-accepted and easily available 2-[F-18]fluoro-2-deoxyglucose ([F-18]FDG) positron emission tomography (PET) tracer as a prosthetic group... 
METASTASIS | PROTEIN | MICROPET | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | CHEMISTRY, MULTIDISCIPLINARY | CANCER ALPHA(V)-INTEGRIN EXPRESSION | DERIVATIZATION | RGD PEPTIDE | POSITRON-EMISSION-TOMOGRAPHY | ALPHA(V)BETA | OXIME | PET | Oligopeptides - chemical synthesis | Radiopharmaceuticals - chemistry | Humans | Fluorodeoxyglucose F18 - metabolism | Fluorodeoxyglucose F18 - chemistry | Neoplasms - diagnosis | Oligopeptides - metabolism | Positron-Emission Tomography - methods | Radiopharmaceuticals - chemical synthesis | Integrin alphaVbeta3 - metabolism | Fluorodeoxyglucose F18 - chemical synthesis | Radiopharmaceuticals - metabolism | Animals | Mice, Nude | Cell Line, Tumor | Mice | Oligopeptides - chemistry
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6. Full Text On the potential for molecular imaging with Cerenkov luminescence
by Lewis, Matthew A and Kodibagkar, Vikram D and Öz, Orhan K and Mason, Ralph P
Optics Letters, ISSN 0146-9592, 12/2010, Volume 35, Issue 23, pp. 3889 - 3891
Recent observation of optical luminescence due to beta decay from suitable radiotracers has led to the possible development of new preclinical optical imaging... 
POSITRON-EMITTING RADIOTRACERS | GADOLINIUM | AGENTS | ABSORPTION | OPTICS
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7. Full Text Whole-body PET/MR imaging: Quantitative evaluation of a novel model-based MR attenuation correction method including bone
by Paulus, Daniel H and Quick, Harald H and Geppert, Christian and Fenchel, Matthias and Zhan, Yiqiang and Hermosillo, Gerardo and Faul, David and Boada, Fernando and Friedman, Kent P and Koesters, Thomas
Journal of Nuclear Medicine, ISSN 0161-5505, 07/2015, Volume 56, Issue 7, pp. 1061 - 1066
In routine whole-body PET/MR hybrid imaging, attenuation correction (AC) is usually performed by segmentation methods based on a Dixon MR sequence providing up... 
MR-based attenuation correction | Attenuation correction of bone | Model-based attenuation correction | PET/MR hybrid imaging | attenuation correction of bone | model-based attenuation correction | SCANNER | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CLINICAL-EXPERIENCE | Bone and Bones - pathology | Radiopharmaceuticals - chemistry | Humans | Middle Aged | Fluorodeoxyglucose F18 - chemistry | Male | Tomography, X-Ray Computed | Positron-Emission Tomography | Magnetic Resonance Imaging | Multimodal Imaging | Algorithms | Image Processing, Computer-Assisted | Bone and Bones - diagnostic imaging | Aged, 80 and over | Adult | Female | Whole Body Imaging | Aged | MR hybrid imaging | PET
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8. Full Text Effectiveness of infliximab in refractory FDG PET-positive sarcoidosis
by Vorselaars, Aiane D M and Crommelin, Heleen A and Deneer, Vera H M and Meek, Bob and Claessen, Anke M E and Keijsers, Ruth G M and van Moorsel, Coline H M and Grutters, JC
European Respiratory Journal, ISSN 0903-1936, 07/2015, Volume 46, Issue 1, pp. 175 - 185
Inconclusive evidence for the efficacy of infliximab in sarcoidosis hinders the global use of this potentially beneficial drug. To study infliximab efficacy in... 
RHEUMATOID-ARTHRITIS | THERAPY | CROHNS-DISEASE | EFFICACY | RESPIRATORY SYSTEM | METHOTREXATE | RANDOMIZED-TRIAL | QUALITY-OF-LIFE | TROUGH LEVELS | CLINICAL-RESPONSE | DISEASE-ACTIVITY | Prospective Studies | Sarcoidosis, Pulmonary - drug therapy | Humans | Middle Aged | Fluorodeoxyglucose F18 - chemistry | Male | Treatment Outcome | Inflammation | Positron-Emission Tomography | Infliximab - therapeutic use | Lung - drug effects | Sarcoidosis, Pulmonary - diagnostic imaging | Anti-Inflammatory Agents - therapeutic use | Quality of Life | Female | Aged | Respiratory Function Tests
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9. Full Text Assessing the feasibility of intranasal radiotracer administration for in brain PET imaging
by Singh, Nisha and Veronese, Mattia and O'Doherty, Jim and Sementa, Teresa and Bongarzone, Salvatore and Cash, Diana and Simmons, Camilla and Arcolin, Marco and Marsden, Paul K and Gee, Antony and Turkheimer, Federico E
Nuclear Medicine and Biology, ISSN 0969-8051, 11/2018, Volume 66, pp. 32 - 39
The development of clinically useful tracers for PET imaging is enormously challenging and expensive. The intranasal (IN) route of administration is purported... 
Neuroimaging | Brain PET imaging | Intranasal | Blood brain barrier | Nose-to-brain pathway | NASAL | ANTAGONIST | DRUG-DELIVERY | CONTAMINATION | INTRAVENOUS DELIVERY | CEREBROSPINAL-FLUID | TRANSPORT | OXYTOCIN | CENTRAL-NERVOUS-SYSTEM | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | BLOOD | Fluorodeoxyglucose F18 - administration & dosage | Olfactory Bulb - diagnostic imaging | Fluorodeoxyglucose F18 - pharmacokinetics | Brain - diagnostic imaging | Benzamides - pharmacokinetics | Pyrrolidines - pharmacokinetics | Humans | Pyrrolidines - administration & dosage | Rats | Fluorodeoxyglucose F18 - chemistry | Male | Administration, Intranasal | Pyrrolidines - chemistry | Rats, Sprague-Dawley | Feasibility Studies | Tissue Distribution | Benzamides - administration & dosage | Animals | Radiochemistry | Benzamides - chemistry | Positron Emission Tomography Computed Tomography - methods | PET imaging | Pets | Neurosciences
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10. Full Text Efficient bioconjugation of 5-fluoro-5-deoxy-ribose (FDR) to RGD peptides for positron emission tomography (PET) imaging of alpha(v)beta(3) integrin receptor
by Dall'Angelo, S and Zhang, QZ and Fleming, IN and Piras, M and Schweiger, LF and O'Hagan, D and Zanda, M
ORGANIC & BIOMOLECULAR CHEMISTRY, ISSN 1477-0520, 07/2013, Volume 11, Issue 27, pp. 4551 - 4558
The utility of 5-fluoro-5-deoxyribose (FDR) as an efficient bioconjugation agent for radiolabelling of the RGD peptides c(RGDfK) and c(RGDfC) is demonstrated.... 
F-18-GALACTO-RGD | OCTREOTIDE | METHODOLOGY | CANCER-PATIENTS | ACID | ANGIOGENESIS | CHEMISTRY, ORGANIC | BIODISTRIBUTION | EXPRESSION | DOSIMETRY | F-18 | Integrin alphaVbeta3 - analysis | Humans | Cell Line, Tumor | Fluorodeoxyglucose F18 - metabolism | Fluorodeoxyglucose F18 - chemistry | Oligopeptides - metabolism | Positron-Emission Tomography - methods | Oligopeptides - chemistry | Integrin alphaVbeta3 - metabolism
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11. Synthesis of [18F]2B-SRF101: A Sulfonamide Derivative of the Fluorescent Dye Sulforhodamine 101
by Kreimerman, Ingrid and Porcal, Williams and Olivera, Silvia and Oliver, Patricia and Savio, Eduardo and Engler, Henry
Current radiopharmaceuticals, 11/2017, Volume 10, Issue 3, pp. 212 - 220
The red fluorescent dye Sulforhodamine 101 (SR101) has been used in neuroscience research as a useful tool for staining of astrocytes, since it has been... 
Fluorine-18 | sulfonamide | Sulforhodamine 101 | astrocyte marker | Positron emission tomography | radiopharmaceutical | Fluorodeoxyglucose F18 - chemistry | Radiochemistry - methods | Rhodamines - chemistry | Sulfonamides - chemistry | Radiopharmaceuticals - chemical synthesis
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12. Full Text Repeatability of Radiomic Features in Non-Small-Cell Lung Cancer [F-18]FDG-PET/CT Studies: Impact of Reconstruction and Delineation
by van Velden, Floris H. P and Kramer, Gerbrand M and Frings, Virginie and Nissen, Ida A and Mulder, Emma R and de Langen, Aianus J and Hoekstra, Otto S and Smit, Egbert F and Boellaard, Ronald
Molecular Imaging and Biology, ISSN 1536-1632, 10/2016, Volume 18, Issue 5, pp. 788 - 795
To assess (1) the repeatability and (2) the impact of reconstruction methods and delineation on the repeatability of 105 radiomic features in non-small-cell... 
Repeatability | Tracer uptake heterogeneity | Medicine & Public Health | Non-small-cell lung cancer (NSCLC) | PET/CT | Imaging / Radiology | Radiomics | UPTAKE HETEROGENEITY | TEST-RETEST | VOLUME | CHEMORADIOTHERAPY | F-18-FDG PET | UPTAKE VALUES | IMAGES | TUMOR TEXTURE ANALYSIS | FRACTAL ANALYSIS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | QUANTITATIVE FDG-PET | Carcinoma, Non-Small-Cell Lung - pathology | Reproducibility of Results | Demography | Humans | Middle Aged | Fluorodeoxyglucose F18 - chemistry | Lung Neoplasms - pathology | Male | Positron Emission Tomography Computed Tomography | Image Processing, Computer-Assisted | Female | Lung Neoplasms - diagnostic imaging | Aged | Carcinoma, Non-Small-Cell Lung - diagnostic imaging | PET
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13. Full Text Performing multi-step chemical reactions in microliter-sized droplets by leveraging a simple passive transport mechanism
by Wang, Jia and Chao, Philip H and Hanet, Sebastian and Van Dam, R. Michael
Lab on a Chip, ISSN 1473-0197, 2017, Volume 17, Issue 24, pp. 4342 - 4355
Despite the increasing importance of positron emission tomography (PET) imaging in research and clinical management of disease, access to myriad new... 
CHEMISTRY, ANALYTICAL | POSITRON-EMISSION-TOMOGRAPHY | CHIP | ACTUATION | 2 NONPARALLEL PLATES | RADIOPHARMACEUTICALS | BIOCHEMICAL RESEARCH METHODS | NANOSCIENCE & NANOTECHNOLOGY | DRIVEN | MICROFLUIDIC REACTOR | CHEMISTRY, MULTIDISCIPLINARY | PET | Fluorodeoxyglucose F18 - pharmacokinetics | Brain - diagnostic imaging | Radioactive Tracers | Benzamides - pharmacokinetics | Microfluidic Analytical Techniques - instrumentation | Fluorodeoxyglucose F18 - chemistry | Positron-Emission Tomography | Brain - metabolism | Positron Emission Tomography Computed Tomography | Microfluidics - instrumentation | Animals | Electrowetting | Female | Mice | Mice, Inbred BALB C | Microfluidics - methods | Benzamides - chemistry | Medical imaging | Chips | Positron emission | Chip formation | Chemical reactions | Fluorine isotopes | Radioactive tracers | Disease control | Complexity | Wettability | Synthesis | Reagents | Radiochemistry | Tomography | Radiation shielding | Droplets | Microfluidics | Tracers | Droplet synthesis | Organic synthesis | Passive transport | Teflon patterning
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14. Full Text 18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome
by De Prost, Nicolas and Feng, Yan and Wellman, Tyler and Tucci, Mauro R and Costa, Eduardo L and Musch, Guido and Winkler, Tilo and Harris, R. Scott and Venegas, Jose G and Chao, Wei and Vidal Melo, Marcos F
Journal of Nuclear Medicine, ISSN 0161-5505, 11/2014, Volume 55, Issue 11, pp. 1871 - 1877
PET with (18)F-FDG allows for noninvasive assessment of regional lung metabolism reflective of neutrophilic inflammation. This study aimed at determining... 
Adult | Fluorodeoxyglucose F18 | Respiratory distress syndrome | Positron emission tomography | Pulmonary edema | Endotoxemia | Biomarkers - metabolism | Lung - pathology | Lung Injury - pathology | Phosphorylation | Gene Expression Regulation | Fluorodeoxyglucose F18 - chemistry | Pulmonary Edema - diagnostic imaging | Inflammation | Positron-Emission Tomography | Respiratory Distress Syndrome, Adult - diagnostic imaging | Animals | Sheep | Lipopolysaccharides - chemistry | Lung - metabolism | Surface-Active Agents - chemistry | Kinetics | Radiopharmaceuticals | Neutrophils - metabolism | Disease Models, Animal | respiratory distress syndrome | pulmonary edema | fluorodeoxyglucose F18 | adult | positron emission tomography | endotoxemia
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15. Full Text Clinical value of delayed 18F-FDG PET/CT for predicting nipple-areolar complex involvement in breast cancer: A comparison with clinical symptoms and breast MRI
by Yoo, Jang and Kim, Bom Sahn and Chung, Jin and Yoon, Hai-Jeon
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0203649
We aimed to evaluate the predictive value of delayed 18F-FDG PET/CT for identifying malignancies involved in the nipple-areolar complex (NAC) in comparison... 
Multivariate Analysis | Radiopharmaceuticals - chemistry | Area Under Curve | Humans | Middle Aged | Fluorodeoxyglucose F18 - metabolism | Fluorodeoxyglucose F18 - chemistry | Positron Emission Tomography Computed Tomography | Magnetic Resonance Imaging | Nipples - diagnostic imaging | Radiopharmaceuticals - metabolism | Breast Neoplasms - pathology | Adult | Female | ROC Curve | Aged | Breast Neoplasms - diagnosis | Breast Neoplasms - diagnostic imaging | Odds Ratio | Nuclear magnetic resonance--NMR | Positron emission | Acetylcysteine | Fluorine isotopes | Breast cancer | Malignancy | Patients | Magnetic resonance imaging | Biopsy | Tomography | Mastectomy | Breast | Positron emission tomography | Tumors | Cancer | NMR | Nuclear magnetic resonance
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16. Full Text Primary mediastinal B-cell lymphoma and mediastinal gray zone lymphoma: Do they require a unique therapeutic approach?
by Dunleavy, Kieron and Wilson, Wyndham H
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 1, pp. 33 - 39
Primary mediastinal B-cell lymphoma (PMBL) is a subtype of diffuse large B-cell lymphoma (DLBCL) that is putatively derived from a thymic B cell. Accounting... 
REED-STERNBERG CELLS | AMPLIFICATION | RITUXIMAB | NON-HODGKINS-LYMPHOMA | CHOP | DOSE-ADJUSTED EPOCH | CD23 EXPRESSION | JAK2 | HEMATOLOGY | CHEMOTHERAPY | FEATURES | Decision Making | Recurrence | B-Lymphocytes - cytology | Immunotherapy - methods | Humans | Lymphoma, B-Cell - therapy | Rituximab | Fluorodeoxyglucose F18 - chemistry | Immunophenotyping | Male | Treatment Outcome | Gene Expression Profiling | Positron-Emission Tomography | Lymphoma - metabolism | Drug Therapy - methods | Mediastinal Neoplasms - therapy | Hodgkin Disease - therapy | Mediastinum - radiation effects | Female | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Index Medicus | Abridged Index Medicus | Aggressive B-Cell Lymphomas | Review Series
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