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JAMA, ISSN 0098-7484, 07/2011, Volume 306, Issue 3, pp. 269 - 276
Journal Article
Journal Article
Tetrahedron, ISSN 0040-4020, 12/2016, Volume 72, Issue 50, pp. 8294 - 8308
Journal Article
Colloids and Surfaces B: Biointerfaces, ISSN 0927-7765, 2011, Volume 85, Issue 2, pp. 349 - 359
► We have developed a novel amphiphile chemotherapy prodrug, 5-FCPal. ► 5-FCPal self-assembles into a non-swelling lamellar crystalline material. ► 5-FCPal can... 
Self-assembly | Chemotherapy | Prodrug | Nanomedicine | Solid lipid nanoparticles | 5-FU | BUCCAL DELIVERY-SYSTEMS | DISPERSIONS | DESIGN | MATERIALS SCIENCE, BIOMATERIALS | LIQUID-CRYSTALLINE | UREA SURFACTANTS | DRUG-DELIVERY | D-RIBOSE | CHEMISTRY, PHYSICAL | ORAL FLUOROPYRIMIDINE CARBAMATE | VEHICLES | BIOPHYSICS | MONOETHANOLAMIDE LIPIDS | Deoxycytidine - chemistry | Nanoparticles - chemistry | Capecitabine | Colloids | Humans | Deoxycytidine - pharmacology | Prodrugs - chemistry | Lipids - chemistry | X-Ray Diffraction | Mammary Neoplasms, Experimental - pathology | Water - chemistry | Female | Molecular Structure | Mammary Neoplasms, Experimental - drug therapy | Cell Line | Microscopy, Electron, Transmission | Fluorouracil - analogs & derivatives | Nanoparticles - ultrastructure | Thermogravimetry | Scattering, Small Angle | Cryoelectron Microscopy | Particle Size | Animals | Tumor Burden - drug effects | Fluorouracil - chemistry | Cell Line, Tumor | Calorimetry, Differential Scanning | Cell Proliferation - drug effects | Fluorouracil - pharmacology | Mice | Mice, Inbred BALB C | Prodrugs - pharmacology | Transition Temperature | Deoxycytidine - analogs & derivatives | Nanoparticles | Cancer | Index Medicus | CARBAMATES | HYDROCARBONS | MAMMARY GLANDS | NEOPLASMS | THERMAL ANALYSIS | TOXICITY | IN VIVO | 60 APPLIED LIFE SCIENCES | CHEMOTHERAPY | CYTIDINE | IN VITRO | CHAINS | LIPIDS
Journal Article
Soft Matter, ISSN 1744-683X, 01/2011, Volume 7, Issue 12, pp. 5764 - 5776
A series of prodrug analogues based on the established chemotherapy agent, 5-fluorouracil, have been prepared and characterized. C18 alkyl and alkenyl chains... 
Self assembly | Surgical implants | Biomedical materials | Chemotherapy | Biocompatibility | Nanomaterials | Nanostructure | Cancer
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109668 - e109668
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 2011, Volume 46, Issue 4, pp. 993 - 1005
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 8/2014, Volume 32, Issue 2, pp. 491 - 504
In the present study, we evaluated the antitumor effect of two synthetic analogs of vitamin D, namely PRI-2191 [(24R)-1,24-dihydroxyvitamin D3] and PRI-2205... 
5-fluorouracil | combined treatment | vitamin D analogs | colon cancer | Combined treatment | Colon cancer | Vitamin d analogs | CARCINOMA-CELLS | ANTIPROLIFERATIVE ACTIVITY | E-CADHERIN | ANTICANCER ACTIVITY | IN-VITRO | CALCIUM-SENSING RECEPTOR | ONCOLOGY | ACCURATE DOCKING | STRUCTURAL BASIS | COLORECTAL-CANCER | 1,25-DIHYDROXYVITAMIN D-3 | Drug Administration Schedule | Colonic Neoplasms - drug therapy | Humans | Dihydroxycholecalciferols - pharmacology | Receptors, Calcitriol - metabolism | Antimetabolites, Antineoplastic - administration & dosage | Dose-Response Relationship, Drug | Drug Synergism | HT29 Cells | Xenograft Model Antitumor Assays | Calcitriol - administration & dosage | Calcitriol - analogs & derivatives | Dihydroxycholecalciferols - administration & dosage | Animals | Fluorouracil - administration & dosage | Signal Transduction - drug effects | Calcitriol - pharmacology | Colonic Neoplasms - pathology | Female | Mice, Inbred NOD | Vitamin D - analogs & derivatives | Mice | Gene Expression Regulation, Neoplastic - drug effects | Cell Cycle - drug effects | Usage | Vitamin D | Calcifediol | Alfacalcidol | Drug therapy | Health aspects | Fluorouracil | Medical research | Ethanol | Colorectal cancer | Vitamin deficiency | Gene expression | Experiments | Cancer therapies | Biological activity | Studies | Proteins | Cell growth | Rodents | Cell cycle | Ligands | Laboratory animals | Pharmaceuticals | Tumors | Apoptosis | Index Medicus
Journal Article