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International Journal of Pharmaceutics, ISSN 0378-5173, 2011, Volume 420, Issue 2, pp. 412 - 418
Journal Article
Clinical Pharmacokinetics, ISSN 0312-5963, 05/2000, Volume 38, Issue 5, pp. 377 - 392
Effective use of the growing number of nonsteroidal anti-inflammatory drugs (NSAIDs), a group that has recently been augmented by the introduction of the... 
Research and development | Suprofen, pharmacokinetics | Sulindac, pharmacokinetics | Mefenamic acid, pharmacokinetics | Carprofen, pharmacokinetics | Indobufen, pharmacokinetics | Ketorolac, pharmacokinetics | Pirprofen, pharmacokinetics | Celecoxib, pharmacokinetics | Oxaprozin, pharmacokinetics | Oxyphenbutazone, pharmacokinetics | Azapropazone, pharmacokinetics | Nabumetone, pharmacokinetics | Bermoprofen, pharmacokinetics | Diclofenac, pharmacokinetics | Ibuprofen, pharmacokinetics | Benoxaprofen, pharmacokinetics | Diflunisal, pharmacokinetics | Flunoxaprofen, pharmacokinetics | Ketoprofen, pharmacokinetics | Loxoprofen, pharmacokinetics | Alminoprofen, pharmacokinetics | Flobufen, pharmacokinetics | Ximoprofen, pharmacokinetics | Butibufen, pharmacokinetics | Tenoxicam, pharmacokinetics | Meloxicam, pharmacokinetics | Naproxen, pharmacokinetics | Rofecoxib, pharmacokinetics | Piroxicam, pharmacokinetics | Tiaprofenic acid, pharmacokinetics | Flurbiprofen, pharmacokinetics | Indomethacin, pharmacokinetics | Pranoprofen, pharmacokinetics | Fenoprofen, pharmacokinetics | Indoprofen, pharmacokinetics | Etodolac, pharmacokinetics | Nonsteroidal antiinflammatories, pharmacokinetics | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | RHEUMATOID-ARTHRITIS | SYNOVIAL-FLUID | HEALTHY-SUBJECTS | NAPROXEN PHARMACOKINETICS | CIRCADIAN CHANGES | ELDERLY PATIENTS | PHARMACOLOGY & PHARMACY | CLINICAL PHARMACOKINETICS | ANTIINFLAMMATORY DRUGS | INTESTINAL PERMEABILITY | PURE ENANTIOMERS | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Humans | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2014, Volume 96, Issue 3, pp. 349 - 359
The suitability of the capillary dried blood spot (DBS) sampling method was assessed for simultaneous phenotyping of cytochrome P450 (CYP) enzymes and... 
P4502B6 ACTIVITY | VORICONAZOLE | LC-MS/MS | SINGLE-POINT | ORAL MIDAZOLAM | VOLUNTEERS | IN-VIVO | PHARMACOLOGY & PHARMACY | DRUG-METABOLIZING-ENZYMES | KAROLINSKA COCKTAIL | BUPROPION HYDROXYLATION | Predictive Value of Tests | Pharmaceutical Preparations - blood | Caffeine - administration & dosage | Cytochrome P-450 Enzyme Inhibitors | Dried Blood Spot Testing | Humans | Omeprazole - blood | Bupropion - blood | Midazolam - administration & dosage | Substrate Specificity | Male | Chromatography, High Pressure Liquid | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Coffee | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Feasibility Studies | Enzyme Inhibitors - administration & dosage | Young Adult | Chromatography, Reverse-Phase | Tandem Mass Spectrometry | Capsules | Spectrometry, Mass, Electrospray Ionization | Flurbiprofen - administration & dosage | Adult | Dextromethorphan - pharmacokinetics | Terfenadine - blood | ATP-Binding Cassette, Sub-Family B, Member 1 - blood | Pharmaceutical Preparations - administration & dosage | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 Enzyme System - blood | Administration, Oral | Isoenzymes | Caffeine - blood | Omeprazole - administration & dosage | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Carbonated Beverages | Midazolam - pharmacokinetics | Bupropion - administration & dosage | Dextromethorphan - blood | Flurbiprofen - blood | Phenotype | Pilot Projects | Midazolam - blood | Dextromethorphan - administration & dosage | Usage | Glycoproteins | Liquid chromatography | Research | Pharmacokinetics | Cytochrome P-450 | Index Medicus | Abridged Index Medicus
Journal Article
Graefe's Archive for Clinical and Experimental Ophthalmology, ISSN 0721-832X, 12/2017, Volume 255, Issue 12, pp. 2375 - 2380
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 09/2017, Volume 262, pp. 296 - 304
In this work, a fixed-dose combination of gabapentin and flurbiprofen formulated as multilayer tablets has been designed, developed and studied in vitro and in... 
Gabapentin | Multilayer tablets | Fixed-dose combination | Human in vivo studies | Flurbiprofen | IMMEDIATE-RELEASE | METAANALYSIS | DELIVERY SYSTEMS | DRUG-DELIVERY | DOSAGE FORMS | DETRUSOR INSTABILITY | CHEMISTRY, MULTIDISCIPLINARY | ADHERENCE | TABLETS | THERAPY | PHARMACOLOGY & PHARMACY | SUSTAINED-RELEASE | Polymers - administration & dosage | Tablets | GABA Agonists - administration & dosage | Humans | Middle Aged | Male | gamma-Aminobutyric Acid - administration & dosage | Analgesics - pharmacokinetics | Intestines - metabolism | Stomach - metabolism | Delayed-Action Preparations - administration & dosage | Young Adult | Flurbiprofen - administration & dosage | Delayed-Action Preparations - pharmacokinetics | Amines - administration & dosage | Adult | Female | gamma-Aminobutyric Acid - pharmacokinetics | Flurbiprofen - pharmacokinetics | GABA Agonists - pharmacokinetics | Administration, Oral | Food-Drug Interactions | Analgesics - administration & dosage | Cyclohexanecarboxylic Acids - administration & dosage | Cross-Over Studies | Adolescent | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Polymers - pharmacokinetics | Amines - pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Drug Liberation | Cyclohexanecarboxylic Acids - pharmacokinetics | Drug Combinations | Dosage and administration | Drug therapy, Combination | Polymers
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 02/2013, Volume 75, Issue 2, pp. 450 - 462
Journal Article
Journal Article
Alzheimer Disease and Associated Disorders, ISSN 0893-0341, 10/2007, Volume 21, Issue 4, pp. 292 - 299
To evaluate the safety and tolerability and pharmacokinetic properties of R-flurbiprofen (Tarenflurbil) in normal elderly individuals and to determine the... 
Alzheimer disease | R-flurbiprofen | Treatment | treatment | CONTROLLED-TRIAL | GAMMA-SECRETASE INHIBITOR | ALZHEIMERS-DISEASE | ENANTIOMERS | MODEL | PATHOLOGY | CLINICAL NEUROLOGY | MICRODIALYSIS | REDUCTION | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | IN-VIVO | DOUBLE-BLIND
Journal Article
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 09/2016, Volume 119, Issue 3, pp. 284 - 290
Cytochrome P450 (CYP) activity can be assessed using a ‘cocktail’ phenotyping approach. Recently, we have developed a cocktail (Geneva cocktail) which combines... 
2D6 | PARAXANTHINE | BUPROPION | IN-VIVO | PHARMACOLOGY & PHARMACY | TOXICOLOGY | FLURBIPROFEN | METABOLIZING-ENZYMES | COOPERSTOWN 5+1 COCKTAIL | ORAL-CONTRACEPTIVES | P-GLYCOPROTEIN | Caffeine - administration & dosage | Humans | Midazolam - administration & dosage | Male | Genotyping Techniques | Cytochrome P-450 CYP2B6 - metabolism | Terfenadine - administration & dosage | Caffeine - pharmacokinetics | Dose-Response Relationship, Drug | Young Adult | Drug Interactions | Cytochrome P-450 CYP3A - genetics | Dried Blood Spot Testing - methods | Cytochrome P-450 CYP1A2 - genetics | Flurbiprofen - administration & dosage | Adult | Female | Dextromethorphan - pharmacokinetics | Cytochrome P-450 CYP2C9 - metabolism | Terfenadine - pharmacokinetics | Bupropion - pharmacokinetics | Cytochrome P-450 CYP2D6 - genetics | Flurbiprofen - pharmacokinetics | Cytochrome P-450 CYP2B6 - genetics | Omeprazole - administration & dosage | Cytochrome P-450 CYP2C19 - genetics | Terfenadine - analogs & derivatives | Omeprazole - pharmacokinetics | Midazolam - pharmacokinetics | Cytochrome P-450 CYP1A2 - metabolism | Bupropion - administration & dosage | Cytochrome P-450 CYP2C9 - genetics | Cross-Over Studies | Phenotype | Cytochrome P-450 CYP3A - metabolism | Adolescent | Cytochrome P-450 CYP2D6 - metabolism | Cytochrome P-450 Enzyme System - genetics | Cytochrome P-450 CYP2C19 - metabolism | Dextromethorphan - administration & dosage | Medical examination | Drug interactions | Analysis | Methods | Blood | Cytochrome P-450 | Confidence intervals | Cytochrome | Prescription drugs | Drug dosages | Index Medicus
Journal Article