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Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2015, Volume 35, Issue 3, pp. 535 - 546
OBJECTIVE—We previously showed that cholesterol loading in vitro converts mouse aortic vascular smooth muscle cells (VSMC) from a contractile state to one... 
Macrophages | Atherosclerotic | Cholesterol | Atherosclerosis | Plaque | atherosclerosis | MYOCARDIN | FOAM CELL | ACTIVATION | FATTY STREAK | plaque, atherosclerotic | HIGH-DENSITY-LIPOPROTEIN | macrophages | METABOLISM | GENE-EXPRESSION | cholesterol | PERIPHERAL VASCULAR DISEASE | DIFFERENTIATION | HEMATOLOGY | MASTER REGULATOR | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Oligonucleotide Array Sequence Analysis | Atherosclerosis - genetics | Coculture Techniques | Humans | Myocytes, Smooth Muscle - pathology | MicroRNAs - metabolism | Necrosis | Transfection | Time Factors | Trans-Activators - genetics | Cell Transdifferentiation | Sterol Regulatory Element Binding Protein 2 - metabolism | Nuclear Proteins - genetics | Binding Sites | Foam Cells - pathology | Myocytes, Smooth Muscle - metabolism | Aorta, Thoracic - pathology | Foam Cells - metabolism | Disease Models, Animal | Atherosclerosis - pathology | Signal Transduction | Cholesterol, HDL - metabolism | Jurkat Cells | Mice, Inbred C57BL | Gene Expression Regulation | Aorta, Thoracic - metabolism | Gene Expression Profiling - methods | Nuclear Proteins - metabolism | Cholesterol - metabolism | Plaque, Atherosclerotic | Atherosclerosis - metabolism | Mice, Knockout | Cell Lineage | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Apolipoproteins E - genetics | Trans-Activators - metabolism | MicroRNAs - genetics | Phagocytosis | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 2014, Volume 34, Issue 8, pp. 1731 - 1738
OBJECTIVE: Although the role of monocytes in the pathogenesis of atherosclerosis is well established, the persistent vascular inflammation remains largely... 
Monocytes | Inflammation | Epigenomics | Oxidized low-density lipoprotein | Atherosclerosis | atherosclerosis | monocytes | ACTIVATION | STERILE INFLAMMATION | MYOCARDIAL-INFARCTION | MACROPHAGES | epigenomics | HUMAN ENDOTHELIAL-CELLS | MEDIATED HISTONE MODIFICATIONS | RECEPTOR-DEFICIENT MICE | inflammation | TRAINED IMMUNITY | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | oxidized low-density lipoprotein | HEMATOLOGY | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | CD36 Antigens - genetics | Atherosclerosis - genetics | Humans | Monocytes - metabolism | Monocytes - immunology | RNA, Messenger - metabolism | ATP Binding Cassette Transporter 1 - metabolism | Foam Cells - drug effects | DNA Methylation | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | ATP-Binding Cassette Transporters - genetics | CD36 Antigens - metabolism | Time Factors | Inflammation Mediators - metabolism | ATP-Binding Cassette Transporters - metabolism | Scavenger Receptors, Class A - genetics | Epigenesis, Genetic - drug effects | Lipoproteins, LDL - metabolism | Cytokines - genetics | Foam Cells - metabolism | Promoter Regions, Genetic | Atherosclerosis - immunology | Cytokines - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Atherosclerosis - metabolism | Cellular Reprogramming - drug effects | Monocytes - drug effects | Phenotype | Histone-Lysine N-Methyltransferase - metabolism | Foam Cells - immunology | Histones - metabolism | Scavenger Receptors, Class A - metabolism | ATP Binding Cassette Transporter 1 - genetics | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2014, Volume 34, Issue 4, pp. 759 - 767
Journal Article
Circulation Research, ISSN 0009-7330, 02/2010, Volume 106, Issue 2, pp. 383 - 390
RATIONALE:Atherosclerosis is an inflammatory disease in which leukocytes and oxidatively modified lipids accumulate in the arterial intima. Previously, we... 
CD11c diphtheria toxin receptor | Dendritic cells | Foam cells | Atherosclerosis | atherosclerosis | foam cells | ATHEROGENESIS | HOMEOSTASIS | CARDIAC & CARDIOVASCULAR SYSTEMS | IN-VIVO DEPLETION | DEFICIENT MICE | AORTIC INTIMA | IDENTIFICATION | LESIONS | TISSUE-SECTIONS | dendritic cells | DIPHTHERIA-TOXIN RECEPTOR | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | ARTERIAL INTIMA | Immunohistochemistry | Cholesterol, Dietary - administration & dosage | Foam Cells - ultrastructure | Dendritic Cells - pathology | Male | Aorta - metabolism | CD11c Antigen - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | CD11c Antigen - genetics | Hypercholesterolemia - pathology | Female | Foam Cells - pathology | Dendritic Cells - metabolism | Foam Cells - metabolism | Microscopy, Electron, Transmission | Receptors, LDL - genetics | Atherosclerosis - pathology | Endothelial Cells - metabolism | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Receptors, LDL - metabolism | Lipid Metabolism | Mice, Transgenic | Atherosclerosis - metabolism | Mice, Knockout | Aorta - pathology | Tunica Intima - metabolism | Heparin-binding EGF-like Growth Factor | Microscopy, Confocal | Animals | Tunica Intima - pathology | Diphtheria Toxin | Mice | Hypercholesterolemia - chemically induced | Lipids - analysis | Endothelial Cells - pathology | Hypercholesterolemia - metabolism | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 03/2012, Volume 32, Issue 3, pp. 669 - 676
OBJECTIVE—Nicotinic acid (NA) treatment has been associated with benefits in atherosclerosis that are usually attributed to effects on plasma lipoproteins. The... 
atherosclerosis | macrophages | vascular biology | receptors | cholesterol-lowering drugs | LONG-TERM | INTEGRIN VLA-4 | ACTIVATION | DENDRITIC CELLS | KAPPA-B | FOAM CELLS | ENDOTHELIAL-CELLS | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXTENDED-RELEASE NIACIN | Tumor Necrosis Factor-alpha - metabolism | Phosphorylation | Integrin alpha4beta1 - metabolism | Toll-Like Receptor 2 - agonists | Human Umbilical Vein Endothelial Cells - metabolism | Receptors, G-Protein-Coupled - metabolism | Humans | Human Umbilical Vein Endothelial Cells - immunology | Monocytes - metabolism | Monocytes - immunology | Niacin - pharmacology | Receptors, Prostaglandin - metabolism | Receptors, Immunologic - antagonists & inhibitors | Inflammation - metabolism | Transfection | Chemotaxis, Leukocyte - drug effects | I-kappa B Kinase - metabolism | RNA Interference | Inflammation Mediators - metabolism | Toll-Like Receptor 4 - agonists | Chemokine CCL2 - metabolism | Receptors, G-Protein-Coupled - drug effects | Interleukin-6 - metabolism | Receptors, Prostaglandin - antagonists & inhibitors | Receptors, Nicotinic - drug effects | Receptors, Nicotinic - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | Cyclooxygenase 2 Inhibitors - pharmacology | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Inflammation - immunology | Toll-Like Receptor 2 - metabolism | Cell Adhesion - drug effects | Toll-Like Receptor 4 - metabolism | Monocytes - drug effects | Transcription Factor RelA - metabolism | Lipopolysaccharides - pharmacology | Inflammation - genetics | Receptors, G-Protein-Coupled - genetics | Pyrazines - pharmacology | Vascular Cell Adhesion Molecule-1 - metabolism | Receptors, Nicotinic - genetics | Receptors, Immunologic - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3900 - 3908
Journal Article
Histopathology, ISSN 0309-0167, 03/2013, Volume 62, Issue 4, pp. 617 - 631
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2014, Volume 103, Issue 1, pp. 100 - 110
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 02/2009, Volume 29, Issue 2, pp. 173 - 179
OBJECTIVE—We explored the effect of hydrogen sulfide (H2S) on atherosclerotic progression, particularly on intracellular adhesion molecule-1 (ICAM-1) in... 
Hydrogen sulfide | Human umbilical vein endothelial cells | Apolipoprotein E knockout mice | Atherosclerosis | Intercellular adhesion molecule-1 | atherosclerosis | apolipoprotein E knockout mice | HYPERCHOLESTEROLEMIA | INHIBITION | hydrogen sulfide | LIFE-STYLE | INFLAMMATION | human umbilical vein endothelial cells | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | CELL-ADHESION MOLECULES | SMOOTH-MUSCLE-CELLS | OXYGENASE | HEMATOLOGY | E-DEFICIENT MICE | EXPRESSION | intercellular adhesion molecule-1 | Hydrogen Sulfide - metabolism | Tumor Necrosis Factor-alpha - metabolism | Glycine - analogs & derivatives | Aorta - ultrastructure | Body Weight | Apolipoproteins E - deficiency | Muscle, Smooth, Vascular - metabolism | Humans | Cystathionine gamma-Lyase - metabolism | Male | NF-kappa B - metabolism | Aorta - metabolism | I-kappa B Proteins - metabolism | RNA, Messenger - metabolism | Foam Cells - drug effects | Dose-Response Relationship, Drug | Endothelial Cells - ultrastructure | Lipids - blood | Alkynes - pharmacology | Intercellular Adhesion Molecule-1 - blood | Active Transport, Cell Nucleus | Cystathionine gamma-Lyase - genetics | Foam Cells - metabolism | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Sulfides - pharmacology | Atherosclerosis - pathology | Endothelial Cells - metabolism | Aorta - drug effects | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Hydrogen Sulfide - blood | Cystathionine gamma-Lyase - antagonists & inhibitors | Atherosclerosis - metabolism | Cardiovascular Agents - pharmacology | Mice, Knockout | Intercellular Adhesion Molecule-1 - metabolism | Animals | Glycine - pharmacology | Apolipoproteins E - genetics | Mice | Atherosclerosis - prevention & control | Endothelial Cells - drug effects | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 09/2012, Volume 151, Issue 1, pp. 138 - 152
Journal Article