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1. Full Text Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study
by Schmidt, Rebecca J and Tancredi, Daniel J and Ozonoff, Sally and Hansen, Robin L and Hartiala, Jaana and Allayee, Hooman and Schmidt, Linda C and Tassone, Flora and Hertz-Picciotto, Irva
American Journal of Clinical Nutrition, ISSN 0002-9165, 07/2012, Volume 96, Issue 1, pp. 80 - 89
Background: Periconceptional folate is essential for proper neurodevelopment. Objective: Maternal folic acid intake was examined in relation to the risk of... 
UNITED-STATES | NEURODEVELOPMENT | NUTRITION & DIETETICS | DNA METHYLATION | EARLY-PREGNANCY | DIAGNOSTIC INTERVIEW | NEURAL-TUBE DEFECTS | SUPPLEMENT USE | SELECTION | CEREBRAL FOLATE-DEFICIENCY | CHILDREN | Maternal Nutritional Physiological Phenomena | Diet - adverse effects | Humans | Child, Preschool | Child Development Disorders, Pervasive - etiology | Infant | Male | Risk | Developmental Disabilities - genetics | Methylenetetrahydrofolate Reductase (NADPH2) - metabolism | Folic Acid - administration & dosage | Pregnancy Trimester, First | Case-Control Studies | Dietary Supplements - analysis | Methylenetetrahydrofolate Reductase (NADPH2) - genetics | Female | Food, Fortified - analysis | Child Development Disorders, Pervasive - epidemiology | Genetic Association Studies | California - epidemiology | Developmental Disabilities - etiology | Pregnancy Complications - physiopathology | Folic Acid Deficiency - physiopathology | Developmental Disabilities - epidemiology | Pregnancy | Confounding Factors (Epidemiology) | Child Development Disorders, Pervasive - genetics | Polymorphism, Single Nucleotide | Folic acid deficiency | Research | Developmental delay | Risk factors | Pervasive developmental disorders | Autism | Maternal & child health | Nutrition | Metabolism | Vitamin B | Index Medicus | Abridged Index Medicus
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2. Full Text Low maternal vitamin B-12 status is associated with offspring insulin resistance regardless of antenatal micronutrient supplementation in rural Nepal
by Stewart, Christine P and Christian, Parul and Schulze, Kerry J and Arguello, Margia and LeClerq, Steven C and Khatry, Subarna K and West Jr, Keith P
Journal of Nutrition, ISSN 0022-3166, 10/2011, Volume 141, Issue 10, pp. 1912 - 1917
Questions have been raised about potentially negative effects of antenatal folic acid use in populations with a high prevalence of vitamin B-12 deficiency. Our... 
FOLIC-ACID FORTIFICATION | MICROBIOLOGICAL ASSAY | BIOCHEMICAL INDICATORS | NUTRITION & DIETETICS | PLASMA | DNA METHYLATION | NUTRITION | DEFICIENCIES | PREGNANCY | FOLATE | CHILDREN | Folic Acid - therapeutic use | Maternal Nutritional Physiological Phenomena | Prevalence | Folic Acid - adverse effects | Humans | Folic Acid Deficiency - epidemiology | Male | Anemia, Iron-Deficiency - prevention & control | Folic Acid Deficiency - prevention & control | Vitamin B 12 Deficiency - complications | Prenatal Exposure Delayed Effects - blood | Female | Anemia, Iron-Deficiency - complications | Vitamin B 12 Deficiency - epidemiology | Dietary Supplements - adverse effects | Child | Insulin Resistance | Vitamin B 12 Deficiency - physiopathology | Pregnancy Complications - physiopathology | Zinc - adverse effects | Prenatal Exposure Delayed Effects - etiology | Rural Health | Zinc - therapeutic use | Folic Acid Deficiency - physiopathology | Pregnancy | Folic Acid Deficiency - complications | Folic Acid - blood | Iron, Dietary - therapeutic use | Pregnancy Complications - prevention & control | Iron, Dietary - adverse effects | Vitamin B 12 Deficiency - prevention & control | Nepal - epidemiology | Pregnancy Complications - epidemiology | Cohort Studies | Zinc - deficiency | Development and progression | Insulin resistance | Food and nutrition | Pregnant women | Vitamin B12 deficiency | Risk factors | Index Medicus
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3. Full Text MTHFR deficiency or reduced intake of folate or choline in pregnant mice results in impaired short-term memory and increased apoptosis in the hippocampus of wild-type offspring
by Jadavji, N.M and Deng, L and Malysheva, O and Caudill, M.A and Rozen, R
Neuroscience, ISSN 0306-4522, 2015, Volume 300, pp. 1 - 9
Highlights • Maternal MTHFR deficiency in mice resulted in short-term memory impairment in pups. • Reduced maternal dietary folate or choline also led to... 
Neurology | MTHFR deficiency | apoptosis | short-term memory | maternal folate deficiency | maternal choline deficiency | Maternal choline deficiency | Maternal folate deficiency | Short-term memory | Apoptosis | OXIDATIVE STRESS | COMMON MUTATION | METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY | FOLIC-ACID | NEUROSCIENCES | MASS-SPECTROMETRY | MOUSE HIPPOCAMPUS | ADVERSE REPRODUCTIVE OUTCOMES | METABOLISM | LOW DIETARY-FOLATE | BRAIN | Memory Disorders - physiopathology | Maternal Nutritional Physiological Phenomena | Male | Memory, Short-Term - physiology | Choline O-Acetyltransferase - metabolism | Recognition (Psychology) - physiology | Homocystinuria - physiopathology | Psychotic Disorders - physiopathology | Female | Methylenetetrahydrofolate Reductase (NADPH2) - deficiency | Hippocampus - growth & development | Memory Disorders - pathology | Disease Models, Animal | Maze Learning - physiology | Homocysteine - blood | Organ Size | Mice, Transgenic | Hippocampus - pathology | Pregnancy Complications - physiopathology | Folic Acid Deficiency - physiopathology | Pregnancy | Choline Deficiency - physiopathology | Animals | Memory Disorders - etiology | Neurogenesis - physiology | Muscle Spasticity - physiopathology | Apoptosis - physiology | Body Weight - physiology | Hippocampus - physiopathology | Brain | Choline | Folic acid | Index Medicus
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4. Full Text Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism
by Martínez-Vega, Raquel and Garrido, Francisco and Partearroyo, Teresa and Cediel, Rafael and Zeisel, Steven H and Martínez-Álvarez, Concepción and Varela-Moreiras, Gregorio and Varela-Nieto, Isabel and Pajares, María A
FASEB Journal, ISSN 0892-6638, 02/2015, Volume 29, Issue 2, pp. 418 - 432
Nutritional imbalance is emerging as a causative factor of hearing loss. Epidemiologic studies have linked hearing loss to elevated plasma total homocysteine... 
Dietary restriction | Hyperhomocysteinemia | Hair cell loss | Methionine cycle | Apoptosis | methionine cycle | hyperhomocysteinemia | INNER-EAR | S-METHYLTRANSFERASE | GUINEA-PIG COCHLEA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | apoptosis | NOISE | GLUTATHIONE SYNTHESIS | CELL BIOLOGY | hair cell loss | REACTIVE OXYGEN | ADENOSINE KINASE | BIOLOGY | MICE | METHIONINE METABOLISM | dietary restriction | Hair Cells, Auditory - cytology | Oxidative Stress | Hearing Loss - etiology | Homocysteine - metabolism | Chromatography, High Pressure Liquid | Hyperhomocysteinemia - physiopathology | Homocysteine - deficiency | Female | Glutathione Synthase - metabolism | In Situ Nick-End Labeling | Glutathione Peroxidase - metabolism | Hearing Loss - physiopathology | Oxidation-Reduction | Methionine - metabolism | Mice, Inbred C57BL | Cochlea - physiopathology | Mice, Transgenic | Folic Acid Deficiency - physiopathology | Catalase - metabolism | Animals | Folic Acid Deficiency - complications | Folic Acid - blood | Mice | Hyperhomocysteinemia - complications | Betaine-Homocysteine S-Methyltransferase - genetics | Index Medicus | Research Communication
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5. Full Text Erythropoietin Levels in Elderly Patients with Anemia of Unknown Etiology
by Gowanlock, Zachary and Sriram, Swetha and Martin, Alison and Xenocostas, Anargyros and Lazo-Langner, Alejandro
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, pp. e0157279 - e0157279
Background In many elderly patients with anemia, a specific cause cannot be identified. This study investigates whether erythropoietin levels are... 
IMPACT | UNEXPLAINED ANEMIA | MULTIDISCIPLINARY SCIENCES | RISK | COHORT | QUALITY-OF-LIFE | EQUATION | Anemia, Iron-Deficiency - physiopathology | Anemia - blood | Vitamin B 12 Deficiency - blood | Humans | Middle Aged | Male | Hematologic Tests | Myelodysplastic Syndromes - blood | Renal Insufficiency, Chronic - complications | Anemia, Iron-Deficiency - blood | Anemia - physiopathology | Erythropoietin - blood | Vitamin B 12 Deficiency - complications | Aged, 80 and over | Female | Renal Insufficiency, Chronic - diagnosis | Retrospective Studies | Anemia - etiology | Folic Acid Deficiency - blood | Myelodysplastic Syndromes - physiopathology | Glomerular Filtration Rate | Comorbidity | Vitamin B 12 Deficiency - diagnosis | Anemia - diagnosis | Hemoglobins - metabolism | Linear Models | Vitamin B 12 Deficiency - physiopathology | Biomarkers - blood | Myelodysplastic Syndromes - complications | Renal Insufficiency, Chronic - physiopathology | Folic Acid Deficiency - physiopathology | Renal Insufficiency, Chronic - blood | Myelodysplastic Syndromes - diagnosis | Folic Acid Deficiency - complications | Anemia, Iron-Deficiency - diagnosis | Aged | Folic Acid Deficiency - diagnosis | Chronic Disease | Elderly people | Health sciences | Erythropoietin | Laboratories | Pathogenesis | Medical records | Systematic review | Iron | Vitamin B12 | Epidemiology | Myelodysplastic syndrome | Folic acid | Regression models | Etiology | Hemoglobin | Chronic illnesses | Nutrient deficiency | Kidneys | Hematology | Epidermal growth factor receptors | Anemia | Mortality | Regression analysis | Patients | Glomerular filtration rate | Medicine | Hypoxia | Kidney diseases | Electronic health records | Elderly | Geriatrics | Index Medicus
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6. Full Text Cobalamin and folate status predicts mental development scores in North Indian children 12-18 mo of age
by Strand, Tor A and Taneja, Sunita and Ueland, Per M and Refsum, Helga and Bahl, Rajiv and Schneede, Joern and Sommerfelt, Halvor and Bhandari, Nita and Medicinska fakulteten and Institutionen för farmakologi och klinisk neurovetenskap and Klinisk farmakologi and Umeå universitet
American Journal of Clinical Nutrition, ISSN 0002-9165, 02/2013, Volume 97, Issue 2, pp. 310 - 317
Background: Micronutrient deficiencies can affect cognitive function. Many young children in low-and middle-income countries have inadequate cobalamin (vitamin... 
MICROBIOLOGICAL ASSAY | HOMOCYSTEINE | NUTRITION & DIETETICS | PLASMA | MORBIDITY | VITAMIN-B-12 | INDICATORS | MICRONUTRIENT DEFICIENCIES | INFANTS | ZINC SUPPLEMENTATION | COGNITIVE-DEVELOPMENT | Folic Acid - therapeutic use | Prevalence | Cognition Disorders - blood | Methylmalonic Acid - blood | Humans | Developmental Disabilities - prevention & control | Folic Acid Deficiency - epidemiology | Infant | Male | Folic Acid - administration & dosage | Neurogenesis | Vitamin B 12 - therapeutic use | Cognition Disorders - prevention & control | Cognition Disorders - etiology | Folic Acid Deficiency - prevention & control | Female | Child Development | Nutritional Status | Vitamin B 12 Deficiency - epidemiology | Psychomotor Performance | Vitamin B 12 - administration & dosage | Developmental Disabilities - etiology | Homocysteine - blood | India - epidemiology | Vitamin B 12 Deficiency - physiopathology | Biomarkers - blood | Vitamin B 12 - blood | Folic Acid Deficiency - physiopathology | Developmental Disabilities - epidemiology | Folic Acid - blood | Vitamin B 12 Deficiency - prevention & control | Cognition Disorders - epidemiology | Cohort Studies | Care and treatment | Cognition disorders | Research | Vitamin B12 | Health aspects | Folic acid | Plasma | Pediatrics | Ability tests | Cognition & reasoning | Vitamin B | Biomarkers | Vitamin deficiency | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
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7. Full Text Folate and vitamin B12 deficiency and hyperhomocysteinemia promote oxidative stress in adult type 2 diabetes
by Al-Maskari, Masoud Y., M.D., Ph.D and Waly, Mostafa I., M.P.H., Ph.D and Ali, Amanat, Ph.D and Al-Shuaibi, Yusra S., M.Sc and Ouhtit, Allal, M.P.H., Ph.D
Nutrition, ISSN 0899-9007, 2012, Volume 28, Issue 7, pp. e23 - e26
Abstract Objective The purpose of this study was to examine the status of folate and vitamin B12 (B12) in relation to serum homocysteine (HCY) and oxidative... 
Gastroenterology and Hepatology | Oxidative stress | Type 2 diabetes mellitus | Vitamin B12 | Homocysteine | Folate | Hyperhomocysteinemia - epidemiology | Vitamin B 12 Deficiency - ethnology | Prevalence | Oxidative Stress | Diet - adverse effects | Humans | Middle Aged | Folic Acid Deficiency - epidemiology | Male | Folic Acid - administration & dosage | Case-Control Studies | Oxidoreductases - blood | Young Adult | Diabetes Mellitus, Type 2 - ethnology | Hyperhomocysteinemia - physiopathology | Diet - ethnology | Vitamin B 12 Deficiency - complications | Adult | Diabetes Mellitus, Type 2 - etiology | Female | Hyperhomocysteinemia - ethnology | Vitamin B 12 Deficiency - epidemiology | Folic Acid Deficiency - ethnology | Antioxidants - analysis | Diabetes Mellitus, Type 2 - complications | Vitamin B 12 - administration & dosage | Hospitals, University | Vitamin B 12 Deficiency - physiopathology | Vitamin B 12 - blood | Oman - epidemiology | Folic Acid Deficiency - physiopathology | Diabetes Mellitus, Type 2 - blood | Folic Acid Deficiency - complications | Folic Acid - blood | Outpatient Clinics, Hospital | Hyperhomocysteinemia - complications | Glutathione - blood | Type 2 diabetes | Diet therapy | Folic acid | Vitamins | Studies | Antioxidants | Diabetes | Diet | Index Medicus
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8. Full Text Gene-environment interactions in the causation of neural tube defects: folate deficiency increases susceptibility conferred by loss of Pax3 function
by Burren, Katie A and Savery, Dawn and Massa, Valentina and Kok, Robert M and Scott, John M and Blom, Henk J and Copp, Andrew J and Greene, Nicholas D.E
Human Molecular Genetics, ISSN 0964-6906, 12/2008, Volume 17, Issue 23, pp. 3675 - 3685
Risk of neural tube defects (NTDs) is determined by genetic and environmental factors, among which folate status appears to play a key role. However, the... 
SPLOTCH MICE | HOMOCYSTEINE | EMBRYONIC-DEVELOPMENT | METHYLATION CYCLE | RISK-FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE EMBRYOS | GENETICS & HEREDITY | PREVENTION | NEURULATION | TANDEM MASS-SPECTROMETRY | FOLIC-ACID | Paired Box Transcription Factors - genetics | Folic Acid Deficiency - metabolism | PAX3 Transcription Factor | Neural Tube Defects - physiopathology | Humans | Neural Tube Defects - embryology | Neural Tube Defects - genetics | Disease Susceptibility - metabolism | Homocysteine - blood | Male | Mice, Transgenic | Neural Tube Defects - metabolism | Homocysteine - metabolism | Folic Acid Deficiency - physiopathology | Animals | Folic Acid Deficiency - embryology | Folic Acid - blood | Folic Acid - metabolism | Female | Mice | Mutation | Methylation | Folic Acid Deficiency - genetics | Paired Box Transcription Factors - metabolism | Index Medicus
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9. Full Text S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production
by Fuso, Andrea and Seminara, Laura and Cavallaro, Rosaria A and D'Anselmi, Fabrizio and Scarpa, Sigfrido
Molecular and Cellular Neuroscience, ISSN 1044-7431, 2005, Volume 28, Issue 1, pp. 195 - 204
Few diseases are characterized by high homocysteine (HCY) and low folate and vitamin B12 blood levels. Alzheimer disease (AD) is among these. It has already... 
HOMOCYSTEINE | RISK-FACTOR | ALZHEIMERS-DISEASE | MEMORY DEFICITS | A-BETA | NEURONS | PRECURSOR PROTEIN | GAMMA-SECRETASE | NEUROSCIENCES | BRAIN | PRESENILIN-1 | Alzheimer Disease - etiology | Folic Acid Deficiency - metabolism | Presenilin-1 | Gene Expression - drug effects | Gene Expression - genetics | Humans | Homocysteine - metabolism | Promoter Regions, Genetic - drug effects | Promoter Regions, Genetic - genetics | Brain - metabolism | DNA Methylation | Aspartic Acid Endopeptidases | Amyloid Precursor Protein Secretases | Vitamin B 12 Deficiency - complications | Membrane Proteins - metabolism | Vitamin B 12 Deficiency - metabolism | Culture Media, Serum-Free - pharmacology | Endopeptidases - metabolism | Alzheimer Disease - physiopathology | Membrane Proteins - genetics | Amyloid beta-Peptides - biosynthesis | Brain - physiopathology | Vitamin B 12 Deficiency - physiopathology | S-Adenosylmethionine - pharmacology | Folic Acid Deficiency - physiopathology | Endopeptidases - genetics | Folic Acid Deficiency - complications | Alzheimer Disease - metabolism | Cell Line, Tumor | S-Adenosylmethionine - metabolism | Amyloid beta-Protein Precursor - biosynthesis | Index Medicus
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10. Full Text Intergenerational impact of paternal lifetime exposures to both folic acid deficiency and supplementation on reproductive outcomes and imprinted gene methylation
by Ly, Lundi and Chan, Donovan and Aarabi, Mahmoud and Landry, Mylène and Behan, Nathalie A and MacFarlane, Amanda J and Trasler, Jacquetta
Molecular Human Reproduction, ISSN 1360-9947, 07/2017, Volume 23, Issue 7, pp. 461 - 477
Do paternal exposures to folic acid deficient (FD), and/or folic acid supplemented (FS) diets, throughout germ cell development adversely affect male germ... 
Sperm | DNA methylation | Epigenetics | Developmental programming | Paternal effects | Male-mediated | Intergenerational effects | Folate | Folic acid | paternal effects | intergenerational effects | NEURAL-TUBE DEFECTS | FOLATE METABOLISM | MOUSE EMBRYOS | TESTICULAR CANCER | PLACENTAL DEVELOPMENT | sperm | male-mediated | DEVELOPMENTAL BIOLOGY | 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE | epigenetics | OBSTETRICS & GYNECOLOGY | folate | REPRODUCTIVE BIOLOGY | SINGLE-BASE RESOLUTION | PREGNANCY OUTCOMES | folic acid | DIETARY-FOLATE | developmental programming | Folic Acid Deficiency - metabolism | Genomic Imprinting | Spermatogenesis - genetics | Embryo, Mammalian | Weaning | Epigenesis, Genetic | Male | Spermatozoa - metabolism | snRNP Core Proteins - metabolism | Folic Acid - administration & dosage | Kruppel-Like Transcription Factors - metabolism | Female | snRNP Core Proteins - genetics | Folic Acid Deficiency - genetics | Animals, Newborn | Spermatogenesis - drug effects | Reproduction - genetics | Spermatozoa - growth & development | RNA, Long Noncoding - genetics | Prenatal Exposure Delayed Effects - physiopathology | Spermatozoa - drug effects | Prenatal Exposure Delayed Effects - metabolism | Folic Acid Deficiency - physiopathology | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Reproduction - drug effects | Animals | Prenatal Exposure Delayed Effects - mortality | Survival Analysis | Folic Acid Deficiency - mortality | Mice | DNA Methylation - drug effects | Dietary Supplements | Kruppel-Like Transcription Factors - genetics | RNA, Long Noncoding - metabolism | Index Medicus | Original Research
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11. Full Text Chronic folate deficiency induces glucose and lipid metabolism disorders and subsequent cognitive dysfunction in mice
by Zhao, Mei and Yuan, Man Man and Yuan, Li and Huang, Li Li and Liao, Jian Hong and Yu, Xiao Ling and Su, Chang and Chen, Yuan Hua and Yang, Yu Ying and Yu, Huan and Xu, De Xiang
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, pp. e0202910 - e0202910
Previous studies have shown that folate levels were decreased in patients with type 2 diabetes (T2D) and further lowered in T2D patients with cognitive... 
GLYCOGEN | FED ICR MICE | HYPERHOMOCYSTEINEMIA | HEPATIC INSULIN-RESISTANCE | HIGH-FAT DIET | MULTIDISCIPLINARY SCIENCES | RATS | MODEL | DIFFERENTIATION | METHYL DONOR | HOMOCYSTEINE-THIOLACTONE | Folic Acid Deficiency - metabolism | Diet - adverse effects | Insulin Resistance | Lipid Metabolism | Cognition | Homocysteine - metabolism | Mice, Inbred ICR | Folic Acid Deficiency - physiopathology | Animals | Folic Acid Deficiency - complications | Time Factors | Folic Acid - blood | Glucose - metabolism | Female | Mice | Cognitive Dysfunction - complications | Folic Acid Deficiency - blood | Type 2 diabetes | Obesity | RNA | Triglycerides | Cognition disorders | Glucose | Insulin | Folic acid | Dextrose | Glucose metabolism | Insulin resistance | Anxiety | Homocysteine | Deficiency diseases | Medical research | Medicine, Experimental | Research | Lipid metabolism | Health aspects | Laboratories | Liver | Spatial discrimination learning | Cognitive ability | Spatial discrimination | Disorders | Impairment | AKT protein | Kinases | Rodents | Diabetes mellitus (non-insulin dependent) | Diabetes mellitus | Vitamin deficiency | CD36 antigen | Metabolism | Gene expression | Patients | Studies | Glucose tolerance | Intolerance | Diet | Spatial memory | Index Medicus
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12. Full Text Brief Report: Autistic Symptoms, Developmental Regression, Mental Retardation, Epilepsy, and Dyskinesias in CNS Folate Deficiency
by Moretti, Paolo and Peters, Sarika U and del Gaudio, Daniela and Sahoo, Trilochan and Hyland, Keith and Bottiglieri, Teodoro and Hopkin, Robert J and Peach, Elizabeth and Min, Sang Hee and Goldman, David and Roa, Benjamin and Bacino, Carlos A and Scaglia, Fernando
Journal of Autism and Developmental Disorders, ISSN 0162-3257, 7/2008, Volume 38, Issue 6, pp. 1170 - 1177
We studied seven children with CNS folate deficiency (CFD). All cases exhibited psychomotor retardation, regression, cognitive delay, and dyskinesia; six had... 
Folic Acid | Pediatrics | Autism | 5-MTHF | Folate transporters | 5-methyltetrahydrofolate | Psychology | Public Health/Gesundheitswesen | Cerebral folate deficiency | Child & School Psychology | cerebral folate deficiency | OXIDATIVE STRESS | folate transporters | PSYCHOLOGY, DEVELOPMENTAL | MALABSORPTION | FOLINIC ACID | CEREBROSPINAL-FLUID | folic Acid | autism | CHILDREN | Neurological Impairments | Language Skills | Psychomotor Skills | Mental Retardation | Developmental Delays | Behavior Problems | Pervasive Developmental Disorders | Genetics | Children | Seizures | Symptoms (Individual Disorders) | Antisocial Behavior | Autistic Disorder - physiopathology | Humans | Tetrahydrofolates - cerebrospinal fluid | Child, Preschool | Infant | Male | Reference Values | Epilepsy - physiopathology | Psychomotor Disorders - psychology | Dyskinesias - psychology | Female |