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PLoS genetics, ISSN 1553-7404, 2019, Volume 15, Issue 7, p. e1008212
Ageing populations pose one of the main public health crises of our time. Reprogramming gene expression by altering the activities of sequence-specific transcription factors (TFs... 
FOXO | GENE | SIGNALING PATHWAY | DOWNSTREAM | DAF-16 | YAN | GENETICS & HEREDITY | TEL | REPRESSOR | OCCUPANCY | FAMILY | Intestinal Mucosa - metabolism | Gene Expression Profiling | Drosophila Proteins - metabolism | Drosophila - physiology | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Adipose Tissue - metabolism | Forkhead Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Neurons - metabolism | Repressor Proteins - metabolism | Drosophila - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - genetics | Longevity | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Lipolysis | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Eye Proteins - metabolism | Metabolic Networks and Pathways | Drosophila Proteins - genetics | Transcription factors | Physiological aspects | Genetic aspects | Comparative analysis | Tissues | Species | Gene regulation | Zoology | Genomes | Insulin-like growth factors | Kinases | Intestine | Coding | Aging | Evolution | Genetics | Forkhead protein | Supervision | Public health | Deoxyribonucleic acid--DNA | University colleges | Gene expression | Insulin | Life span | Insects | Nematodes | Binding sites | Deoxyribonucleic acid | DNA
Journal Article
Redox biology, ISSN 2213-2317, 2015, Volume 6, pp. 51 - 72
Journal Article
Nature Immunology, ISSN 1529-2908, 07/2010, Volume 11, Issue 7, pp. 635 - 643
Journal Article
BMC Genomics, ISSN 1471-2164, 12/2010, Volume 11, Issue 1, pp. 696 - 696
..., 75015 Paris, France Background During embryonic development, the Pax family of transcription factors play important roles in cell type specification... 
SKELETAL-MUSCLE | SMOOTH-MUSCLE | SONIC HEDGEHOG | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | C-MET RECEPTOR | STEM-CELL | ALVEOLAR RHABDOMYOSARCOMA | SATELLITE CELLS | MUSCLE PROGENITOR CELLS | SIGNALING IN-VIVO | PRECURSOR CELLS | Paired Box Transcription Factors - genetics | Genetic Testing | Oligonucleotide Array Sequence Analysis | PAX7 Transcription Factor - genetics | PAX7 Transcription Factor - metabolism | RNA, Messenger - metabolism | Embryo, Mammalian - metabolism | Forkhead Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Base Sequence | Muscle Proteins - metabolism | Transcription, Genetic | PAX3 Transcription Factor | Reproducibility of Results | Histone Deacetylases - genetics | Cell Survival | RNA, Messenger - genetics | Gene Expression Profiling - methods | Histone Deacetylases - metabolism | Signal Transduction - genetics | Forkhead Transcription Factors - genetics | Muscle Proteins - genetics | Animals | Embryo, Mammalian - cytology | Muscle Development - genetics | Forkhead Box Protein O1 | Mice | Paired Box Transcription Factors - metabolism | Physiological aspects | Embryonic development | Transcription factors | Genetic aspects | Myogenesis | Kinases | Embryos | Experiments | Genes | Binding sites | Cell adhesion & migration | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2012, Volume 36, Issue 5, pp. 717 - 730
Regulatory T (Treg) cells, driven by the Foxp3 transcription factor, are responsible for limiting autoimmunity and chronic inflammation... 
LIMITS | TARGET GENES | UBIQUITIN | GENERATION | HISTONE-DEACETYLASE INHIBITORS | INDUCTION | IMMUNOLOGY | INDEPENDENT REGULATION | EXPRESSION | OCCUPANCY | ACETYLTRANSFERASE | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Epigenesis, Genetic | Autoimmunity - genetics | Diabetes Mellitus, Type 1 - metabolism | Histone Acetyltransferases - genetics | Histone Deacetylases - immunology | T-Lymphocytes, Regulatory - immunology | Interleukin-2 - immunology | Autoimmunity - immunology | Forkhead Transcription Factors - metabolism | Histone Acetyltransferases - metabolism | Trans-Activators - genetics | Acetylation | Diabetes Mellitus, Type 1 - immunology | Lysine Acetyltransferase 5 | Transcription Factors - immunology | Carrier Proteins - immunology | Trans-Activators - immunology | Interleukin-2 - metabolism | Transforming Growth Factor beta - immunology | Promoter Regions, Genetic | Histone Deacetylases - genetics | Nerve Tissue Proteins - immunology | Mice, Inbred C57BL | Diabetes Mellitus, Type 1 - genetics | Histone Deacetylases - metabolism | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | Interleukin-2 - genetics | Animals | Carrier Proteins - metabolism | Transforming Growth Factor beta - genetics | Histone Acetyltransferases - immunology | Mice, Inbred NOD | Trans-Activators - metabolism | Mice | Transforming Growth Factor beta - metabolism | Autoimmunity | Oncology, Experimental | Genes | Histones | Research | DNA binding proteins | Diabetes | Transforming growth factors | T cells | Cancer | Transcription factors | Statistical analysis | Rodents | DNA methylation | Epigenetics | T cell receptors | Gene expression | Age
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2009, Volume 206, Issue 12, pp. 2701 - 2715
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 3/2016, Volume 73, Issue 6, pp. 1159 - 1172
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 2011, Volume 31, Issue 9, pp. 3407 - 3422
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2016, Volume 126, Issue 11, pp. 4372 - 4386
...). For instance, insulin signaling to inhibit the transcription factor forkhead box O1a (FOXO1A), which transactivates gluconeogenic enzyme gene expression, might be impaired... 
RAT-LIVER | MEDICINE, RESEARCH & EXPERIMENTAL | METABOLIC SYNDROME | DE-NOVO LIPOGENESIS | TRANSCRIPTION FACTOR FOXO1 | FATTY LIVER-DISEASE | OB/OB MICE | ELEMENT-BINDING PROTEIN | HEPATIC STEATOSIS | ADIPOSE-TISSUE | PLASMA TRIGLYCERIDES | Glucose Intolerance - metabolism | Glucose-6-Phosphatase - genetics | Fatty Liver - pathology | Humans | Male | Glucose - biosynthesis | Glucose Intolerance - pathology | Fatty Liver - chemically induced | Glycolysis - drug effects | Glycolysis - genetics | Lipogenesis - genetics | Female | Glucose Intolerance - chemically induced | Insulin - genetics | Nuclear Proteins - genetics | Fatty Liver - genetics | Forkhead Box Protein O1 - metabolism | Glucose Intolerance - genetics | Fatty Liver - metabolism | Fructose - toxicity | Insulin Resistance | Glucose - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Transcription Factors - genetics | Glucose-6-Phosphatase - metabolism | Mice, Knockout | Transcription Factors - metabolism | Insulin - metabolism | Animals | Signal Transduction - drug effects | Lipogenesis - drug effects | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Mice | Forkhead Box Protein O1 - genetics | Obesity | Analysis | Insulin resistance | Genetic aspects | Genetic transcription | Research | Risk factors | Protein binding | Glucose | Metabolites | Rodents | Liver
Journal Article