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Nature Neuroscience, ISSN 1097-6256, 08/2013, Volume 16, Issue 8, pp. 1154 - 1161
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 05/2016, Volume 183, pp. 128 - 135
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2013, Volume 33, Issue 14, pp. 5881 - 5894
Pain is a complex experience composed of sensory and affective components. Although the neural systems of the sensory component of pain have been studied... 
MESSENGER-RNAS | NONSELECTIVE CATIONIC CONDUCTANCE | ANTERIOR CINGULATE CORTEX | BASOLATERAL AMYGDALA | INDUCED AVERSION | MIDBRAIN DOPAMINE NEURONS | MORPHINE-WITHDRAWAL | DIFFERENTIAL DISTRIBUTION | CRF RECEPTORS | NEUROSCIENCES | VENTRAL TEGMENTAL AREA | Septal Nuclei - drug effects | Cyclohexanes - pharmacology | Septal Nuclei - physiology | Male | Peptide Fragments - pharmacology | Hormones - adverse effects | Pain - chemically induced | Pyridazines - pharmacology | Septal Nuclei - cytology | Arginine - analogs & derivatives | Affective Symptoms - etiology | Pain - complications | Hormones - agonists | Corticotropin-Releasing Hormone - antagonists & inhibitors | Kynurenic Acid - pharmacology | Neuropeptide Y - agonists | Formaldehyde - toxicity | Neurons - drug effects | Neuropeptide Y - antagonists & inhibitors | Action Potentials - drug effects | Xanthenes - pharmacology | Disease Models, Animal | Membrane Potentials - drug effects | Aniline Compounds - pharmacology | Corticotropin-Releasing Hormone - adverse effects | Neuropeptide Y - therapeutic use | Rats | Corticotropin-Releasing Hormone - agonists | Excitatory Amino Acid Antagonists - pharmacology | Pyrimidines - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Hormone Antagonists - pharmacology | Affective Symptoms - drug therapy | Animals | Microdialysis | Analysis of Variance | Arginine - pharmacology | In Vitro Techniques | Pain Measurement | Index Medicus
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 04/2004, Volume 141, Issue 7, pp. 1175 - 1184
1 This study characterises some of the mechanisms and mediators involved in the orofacial nociception triggered by injection of formalin into the upper lip of... 
Formalin | Prostaglandins | Cytokines | Noradrenaline | Bradykinin | THERMAL HYPERALGESIA | CYCLOOXYGENASE-2 | bradykinin | INFLAMMATORY HYPERALGESIA | NECROSIS-FACTOR-ALPHA | B-2 RECEPTOR | NERVE GROWTH-FACTOR | PAIN | formalin | prostaglandins | PHARMACOLOGY & PHARMACY | cytokines | noradrenaline | INHIBITOR | UP-REGULATION | ANALGESIC EFFICACY | Bradykinin - analogs & derivatives | Bradykinin B1 Receptor Antagonists | Captopril - pharmacology | Rats, Wistar | Nociceptors - physiology | Male | Cytokines - physiology | Facial Pain - physiopathology | Cytokines - chemistry | Dose-Response Relationship, Drug | Facial Pain - chemically induced | Tyramine - chemistry | Arachidonic Acids - metabolism | Injections, Subcutaneous | Formaldehyde - administration & dosage | Thiazines - pharmacology | Behavior, Animal - drug effects | Interleukin-8 - pharmacology | Biogenic Amines - physiology | Bradykinin - pharmacology | Atenolol - pharmacology | Pyrazoles - pharmacology | Lip - drug effects | Tyramine - physiology | Rats | Behavior, Animal - physiology | Hindlimb - innervation | Receptor, Bradykinin B2 - physiology | Bradykinin B2 Receptor Antagonists | Celecoxib | Sulfonamides - pharmacology | Arachidonic Acids - pharmacology | Indomethacin - pharmacology | Drug Synergism | Bradykinin - physiology | Tumor Necrosis Factor-alpha - pharmacology | Prostaglandins - physiology | Animals | Interleukin-6 - pharmacology | Lip - innervation | Receptor, Bradykinin B1 - physiology | Hindlimb - drug effects | Thiazoles - pharmacology | Guanethidine - pharmacology | Nociceptors - drug effects | Facial Pain - drug therapy | Index Medicus | Papers
Journal Article
Pain, ISSN 0304-3959, 01/2011, Volume 152, Issue 1, pp. 38 - 44
The TRPA1 receptor is a member of the transient receptor potential (TRP) family of ion channels expressed in nociceptive neurons. TRPA1 receptors are targeted... 
Sensory neurons | Trigeminal ganglia | CGRP | Migraine | Blood flow | EMERGENCY-DEPARTMENT VISITS | TRIGEMINAL GANGLION | GENE-RELATED PEPTIDE | ION-CHANNEL TRPA1 | NEUROGENIC INFLAMMATION | MULTIPLE CHEMICAL-SENSITIVITY | VANILLOID RECEPTOR | BLOOD-FLOW | NEUROSCIENCES | CLINICAL NEUROLOGY | SENSORY NERVE-FIBERS | DURA-MATER | ANESTHESIOLOGY | Mustard Plant | Capsaicin - pharmacology | Garlic - chemistry | Peptide Fragments - pharmacology | Sensory System Agents - pharmacology | Dose-Response Relationship, Drug | Calcium Channels - physiology | Meningeal Arteries - physiology | Calcitonin Gene-Related Peptide - antagonists & inhibitors | Laser-Doppler Flowmetry - methods | Neurons - metabolism | Calcitonin Gene-Related Peptide - metabolism | Neurons - drug effects | Animals, Newborn | Acrolein - pharmacology | Acetanilides - pharmacology | Plant Oils - pharmacology | Trigeminal Ganglion - cytology | TRPC Cation Channels | Calcitonin Gene-Related Peptide - pharmacology | Purines - pharmacology | Cells, Cultured | Formaldehyde - pharmacology | Rats | Capsaicin - analogs & derivatives | Ankyrins - physiology | Meningeal Arteries - drug effects | Animals | Ankyrins - antagonists & inhibitors | TRPA1 Cation Channel | Substance P - metabolism | Vasodilation - drug effects | Blood vessels | Neurosciences | Dilatation | Neurons | Formaldehyde | Index Medicus | trigeminal ganglia | migraine | sensory neurons | blood flow
Journal Article
Journal Article
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 3/2017, Volume 31, Issue 3, pp. 377 - 386
Our previous study indicated that a chiral compound 071031B was a novel serotonin and noradrenaline reuptake inhibitor with superior antidepressant activity... 
pharmacokinetics | serotonin and norepinephrine uptake inhibitors | chiral pharmacology | Antidepressants | behavioral pharmacology | LOW-BACK-PAIN | PSYCHIATRY | NEUROSCIENCES | CLINICAL NEUROLOGY | VENLAFAXINE | NEUROPATHIC PAIN | IN-VITRO | DULOXETINE | LABORATORY-ANIMALS | REMISSION RATES | PHARMACOLOGY & PHARMACY | MAJOR DEPRESSIVE DISORDER | CACO-2 CELLS | Depressive Disorder - drug therapy | Male | Serotonin and Noradrenaline Reuptake Inhibitors - pharmacokinetics | Duloxetine Hydrochloride - pharmacology | Norepinephrine Plasma Membrane Transport Proteins - pharmacokinetics | Depression - drug therapy | Depression - metabolism | Benzodioxoles - pharmacokinetics | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Duloxetine Hydrochloride - pharmacokinetics | Rats | Thiophenes - pharmacology | Depressive Disorder - metabolism | Rats, Sprague-Dawley | Mice, Inbred ICR | Serotonin Plasma Membrane Transport Proteins - metabolism | Swimming - physiology | Thiophenes - pharmacokinetics | Animals | Norepinephrine - metabolism | Serotonin and Noradrenaline Reuptake Inhibitors - pharmacology | Serotonin - metabolism | Mice | Antidepressive Agents - pharmacokinetics | Norepinephrine Plasma Membrane Transport Proteins - pharmacology | Benzodioxoles - pharmacology | Usage | Dosage and administration | Research | Serotonin | Pharmacokinetics | Animal models | Liver | Exploration | Pharmacology | Duloxetine | Mental depression | Metabolism | Enantiomers | pH effects | Formaldehyde | Pain | Intestine | Rodents | Affinity | Norepinephrine | Swimming | In vivo methods and tests | Acetic acid | Noradrenaline | In vitro methods and tests | Index Medicus
Journal Article
Life Sciences, ISSN 0024-3205, 12/2018, Volume 214, pp. 167 - 175
Journal Article