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Journal of Medicinal Chemistry, ISSN 0022-2623, 04/2015, Volume 58, Issue 7, pp. 2988 - 3001
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2013, Volume 56, Issue 15, pp. 6190 - 6199
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2011, Volume 54, Issue 14, pp. 4964 - 4976
The natural antibiotic fosmidomycin acts via inhibition of 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), an essential enzyme in the non-mevalonate... 
VIVO ANTIMALARIAL ACTIVITY | CLINDAMYCIN | CHEMISTRY, MEDICINAL | ISOPRENOID BIOSYNTHESIS | ISOPENTENYL DIPHOSPHATE | ESTER PRODRUGS | TERPENOID BIOSYNTHESIS | ESCHERICHIA-COLI | NON-MEVALONATE PATHWAY | PLASMODIUM-FALCIPARUM MALARIA | NONMEVALONATE PATHWAY | Oxidoreductases - antagonists & inhibitors | Antitubercular Agents - chemical synthesis | Fosfomycin - chemical synthesis | Aldose-Ketose Isomerases - chemistry | Catalytic Domain | Antitubercular Agents - chemistry | Fosfomycin - chemistry | Fosfomycin - pharmacology | Antitubercular Agents - pharmacology | Models, Molecular | Crystallography, X-Ray | Structure-Activity Relationship | Multienzyme Complexes - antagonists & inhibitors | Mycobacterium tuberculosis - drug effects | Oxidoreductases - chemistry | Multienzyme Complexes - chemistry | Mycobacterium tuberculosis - enzymology | Drug Design | Protein Binding | Protein Conformation | Aldose-Ketose Isomerases - antagonists & inhibitors | Fosfomycin - analogs & derivatives | Biological Sciences | Basic Medicine | Other Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Biology | MEDICINE | Chemistry | Naturvetenskap | Biokemi och molekylärbiologi | MEDICIN | Kemi | Biologiska vetenskaper | Medicinska och farmaceutiska grundvetenskaper | Cell and molecular biology | Annan medicinsk grundvetenskap | Biochemistry and Molecular Biology | Biologi | Natural Sciences | Cell- och molekylärbiologi
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The Journal of Organic Chemistry, ISSN 0022-3263, 05/2007, Volume 72, Issue 10, pp. 3783 - 3789
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Journal Article