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1. Full Text Alternative splicing of FOXP3-virtue and vice
by Mailer, Reiner K.W
Frontiers in Immunology, ISSN 1664-3224, 03/2018, Volume 9, p. 530
FOXP3 is the lineage-defining transcription factor of CD4+ CD25+ regulatory T cells. While many aspects of its regulation, interaction, and function are... 
FOXP3Δ2 | Alternative splicing | FOXP3Δ2Δ7 | Antisense oligonucleotides | Isoform | Treg cells | FOXP3 | Th17 cells | RHEUMATOID-ARTHRITIS | ACTIVATION-INDUCED FOXP3 | ANTIBODY-ASSOCIATED VASCULITIS | alternative splicing | MESSENGER-RNA EXPRESSION | BOX PROTEIN-3 FOXP3 | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | IMMUNE DYSREGULATION | TARGET GENES | antisense oligonucleotides | TRANSCRIPTION FACTOR FOXP3 | REGULATORY T-CELLS | FOXP3 Delta 2 | FOXP3 Delta 2 Delta 7 | isoform | Physiological aspects | Transcription factors | Genetic aspects | Research | T cells | RNA splicing
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2. Full Text Intratumoral CD8+ T/FOXP3+ cell ratio is a predictive marker for survival in patients with colorectal cancer
by Suzuki, Hiroyuki and Chikazawa, Nobuhito and Tasaka, Takehiko and Wada, Junji and Yamasaki, Akio and Kitaura, Yoshiki and Sozaki, Masae and Tanaka, Masao and Onishi, Hideya and Morisaki, Takashi and Katano, Mitsuo
Cancer Immunology, Immunotherapy, ISSN 0340-7004, 5/2010, Volume 59, Issue 5, pp. 653 - 661
The human immune system consists of a balance between immune surveillance against non-self antigens and tolerance of self-antigens. CD8+ T cells and CD4+... 
Intratumoral FOXP3 + regulatory T cells | Immunology | Medicine & Public Health | CD8 + T cell/FOXP3 + cell ratio | Colorectal cancer | Intratumoral CD8 + T cells | Prognostic factor | Oncology | Cancer Research | t cell/foxp3 | Intratumoral foxp3 | t cells | CD8 | cell ratio | regulatory t cells | Intratumoral cd8 | TGF-BETA | PROGNOSIS | Intratumoral CD8(+) T cells | PERIPHERAL-BLOOD | OVARIAN-CANCER | IMMUNOLOGY | CUTTING EDGE | TUMOR-INFILTRATING LYMPHOCYTES | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | Intratumoral FOXP3(+) regulatory T cells | TRANSCRIPTION FACTOR FOXP3 | REGULATORY T-CELLS | IMMUNOLOGICAL SELF-TOLERANCE | CD8(+) T cell/FOXP3(+) cell ratio | Forkhead Transcription Factors - immunology | Immunohistochemistry | T-Lymphocyte Subsets - immunology | T-Lymphocytes, Regulatory - metabolism | Prognosis | Humans | Middle Aged | Male | T-Lymphocytes, Regulatory - immunology | Flow Cytometry | Forkhead Transcription Factors - metabolism | Lymphatic Metastasis - pathology | Biomarkers, Tumor - metabolism | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Colorectal Neoplasms - metabolism | Colorectal Neoplasms - mortality | Cell Separation | Kaplan-Meier Estimate | Lymphatic Metastasis - immunology | Disease-Free Survival | Colorectal Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | Aged | CD8-Positive T-Lymphocytes - immunology | Biomarkers, Tumor - immunology | Transforming Growth Factor beta - metabolism | Lymphocytes, Tumor-Infiltrating - immunology
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3. Full Text Maternal Foxp3 Expressing CD4+ CD25+ and CD4+ CD25− Regulatory T‐Cell Populations are Enriched in Human Early Normal Pregnancy Decidua: A Phenotypic Study of Paired Decidual and Peripheral Blood Samples
by Dimova, Tanya and Nagaeva, Olga and Stenqvist, Ann‐Christin and Hedlund, Malin and Kjellberg, Lennart and Strand, Magnus and Dehlin, Eva and Mincheva‐Nilsson, Lucia
American Journal of Reproductive Immunology, ISSN 1046-7408, 07/2011, Volume 66, Issue 1, pp. 44 - 56
Citation Dimova T, Nagaeva O, Stenqvist A‐Christin, Hedlund M, Kjellberg L, Strand M, Dehlin E, Mincheva‐Nilsson L. Maternal Foxp3 Expressing CD4+ CD25+ and... 
CD4+ CD25++ Foxp3+ cells | CD4+ CD25− Foxp3+ cells | pregnancy | Treg cells | CD4+ CD25+ Foxp3+ cells | Foxp3 | human decidua | Pregnancy | CD4 | cells | CD25 | Human decidua | FAS LIGAND | TGF-BETA | TOLERANCE | CD4(+) CD25(+) Foxp3(+) cells | PLACENTA | RECEPTOR | CD4(+) CD25(++) Foxp3(+) cells | IMMUNOLOGY | SUPPRESSION | REPRODUCTIVE BIOLOGY | SPONTANEOUS-ABORTION | TRANSCRIPTION FACTOR FOXP3 | EXPANSION | CD4(+) CD25(-) Foxp3(+) cells | EXOSOMES | Neuropilin-1 - genetics | Antigens, CD - immunology | Forkhead Transcription Factors - biosynthesis | T-Lymphocytes, Regulatory - metabolism | Cytokines - metabolism | Decidua - immunology | Neuropilin-1 - metabolism | Humans | Transforming Growth Factor beta1 - metabolism | CD4-Positive T-Lymphocytes - metabolism | Transforming Growth Factor beta1 - genetics | OX40 Ligand - biosynthesis | Forkhead Transcription Factors - genetics | Antigens, CD - genetics | Antigens, CD - metabolism | Decidua - metabolism | Pregnancy - immunology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Phenotype | OX40 Ligand - immunology | Female | Pregnancy - blood | Cytokines - genetics | Immunohistochemistry | Flow cytometry | decidua | CD223 antigen | Lymphocytes T | Transforming growth factor- beta 1 | CD103 antigen | CTLA-4 protein | Uterus | Peripheral blood | CD25 antigen | Foxp3 protein | Cell survival | Statistical analysis | Cytokines | Immunoregulation | Fetuses | CD62L protein | Gene expression | Immunological tolerance | CD4 antigen | Polymerase chain reaction | Immunosuppression | Immunofluorescence | neuropilin
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4. Full Text The phenotypic and functional consequences of tumour necrosis factor receptor type 2 expression on CD4+ FoxP3+ regulatory T cells
by Chen, Xin and Oppenheim, Joost J
Immunology, ISSN 0019-2805, 08/2011, Volume 133, Issue 4, pp. 426 - 433
Summary Cytokine receptors expressed by CD4+ FoxP3+ regulatory T cells (Treg cells) not only serve as a phenotypic marker for the identification of this... 
immunosuppression | tumour necrosis factor receptor 2 | CD4+ FoxP3+ regulatory T cells | CD4+ FoxP3− effector T cells | immunological phenotype | regulatory T cells | CD4 | Immunosuppression | effector T cells | Tumour necrosis factor receptor 2 | FoxP3 | Immunological phenotype | RHEUMATOID-ARTHRITIS | POPULATION | CD4(+) FoxP3(-) effector T cells | MECHANISM | TOLERANCE | CD4(+) FoxP3(+) regulatory T cells | INDUCTION | IMMUNOLOGY | SUPPRESSION | P75 | AUTOIMMUNITY | COSTIMULATOR | TNF-ALPHA | Forkhead Transcription Factors - immunology | CD4 Antigens - immunology | Phenotype | Animals | Receptors, Tumor Necrosis Factor, Type II - biosynthesis | Humans | T-Lymphocytes, Regulatory - cytology | Receptors, Tumor Necrosis Factor, Type II - immunology | T-Lymphocytes, Regulatory - immunology | Drug therapy | Lymphocytes | Immune system | CD4+ FoxP3+ regulatory T cells | Review | CD4+ FoxP3− effector T cells
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5. Full Text Infiltrating Foxp3+ Regulatory T Cells From Spontaneously Tolerant Kidney Allografts Demonstrate Donor‐Specific Tolerance
by Hu, M and Wang, C and Zhang, G. Y and Saito, M and Wang, Y. M and Fernandez, M. A and Wang, Y and Wu, H and Hawthorne, W. J and Jones, C and O'Connell, P. J and Sparwasser, T and Bishop, G. A and Sharland, A. F and Alexander, S. I
American Journal of Transplantation, ISSN 1600-6135, 11/2013, Volume 13, Issue 11, pp. 2819 - 2830
Foxp3+ regulatory T cells (Tregs) have an essential role in immune and allograft tolerance. However, in both kidney and liver transplantation in humans, FOXP3+... 
donor alloantigen‐specific tolerance | kidney allograft infiltrating Foxp3+ Tregs | DEREG mice | Depletion of Foxp3+ Tregs | spontaneous kidney allograft tolerance | kidney allograft infiltrating Foxp3 | Depletion of Foxp3 | Tregs | donor alloantigen-specific tolerance | LONG-TERM | SURGERY | kidney allograft infiltrating Foxp3(+) Tregs | LIVER ALLOGRAFTS | IFN-GAMMA | Depletion of Foxp3(+) Tregs | RENAL-ALLOGRAFTS | TRANSPLANTATION | TRANSPLANTATION TOLERANCE | IMMUNE-RESPONSES | REJECTION | IN-VIVO | MICE | ACCEPTANCE | T-Lymphocytes, Regulatory - metabolism | Graft Survival - immunology | Inflammation Mediators | Cytokines - metabolism | Mice, Inbred C57BL | Male | Forkhead Transcription Factors - physiology | Kidney Transplantation | Mice, Inbred C3H | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Allografts | Animals | Immune Tolerance - immunology | Mice, Inbred DBA | Skin Transplantation | Mice | Graft Rejection - immunology | Tissue Donors | Transplantation Tolerance - immunology | Genes, Reporter | Transplantation | Kidneys | T cells | Transforming growth factors | Homografts | Transplants & implants | Lymphocytes
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6. Full Text The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells
by Gregori, Silvia and Goudy, Kevin S and Roncarolo, Maria Grazia
Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3, p. 30
The immuno-regulatory mechanisms of IL-10-producing type 1 regulatory T (Tr1) cells have been widely studied over the years. However, several recent... 
Immunotolerance | Foxp3 | Tr1 cells | IL-10 | HUMAN CD4 | PERIPHERAL-BLOOD | IMMUNOLOGY | LATENT TGF-BETA | C-MAF | CUTTING EDGE | RECOMBINANT HUMAN INTERLEUKIN-10 | IMMATURE DENDRITIC CELLS | GROWTH-FACTOR-BETA | IN-VITRO | CYTOKINE PRODUCTION | immunotolerance | FOXP3(+) T-reg | FOXP3 Treg
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7. Full Text Regulatory T Cells: Mechanisms of Differentiation and Function
by Josefowicz, Steven Z and Lu, Li-Fan and Rudensky, Alexander Y
Annual Review of Immunology, ISSN 0732-0582, 4/2012, Volume 30, Issue 1, pp. 531 - 564
The immune system has evolved to mount an effective defense against pathogens and to minimize deleterious immune-mediated inflammation caused by commensal... 
immune homeostasis | autoimmunity | Foxp3 | tolerance | Autoimmunity | Tolerance | Immune homeostasis | TGF-BETA | INFECTIOUS TRANSPLANTATION TOLERANCE | TRANS-RETINOIC ACID | IMMUNOLOGY | CUTTING EDGE | THYMIC EPITHELIAL-CELLS | TRANSCRIPTION FACTOR FOXP3 | SPONTANEOUS AUTOIMMUNE ENCEPHALOMYELITIS | IMMUNOLOGICAL SELF-TOLERANCE | NF-KAPPA-B | BETA-MEDIATED INDUCTION | T-Lymphocytes, Regulatory - metabolism | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Humans | Gene Expression Regulation | Homeostasis - immunology | Immune Tolerance | MicroRNAs - metabolism | Forkhead Transcription Factors - genetics | MicroRNAs - immunology | T-Lymphocytes, Regulatory - immunology | Animals | Forkhead Transcription Factors - metabolism | T-Lymphocytes, Regulatory - cytology | Protein Binding | Receptors, Antigen, T-Cell - immunology | Thymus Gland - immunology | Transcription, Genetic | Cell Differentiation | Enzyme Activation | Proto-Oncogene Proteins c-akt - metabolism | Thymus Gland - metabolism | Cytokines - immunology | Physiological aspects | Microorganisms | Inflammation | Immune response | Research | Health aspects | Pathogens | Transcription factors | Commensals | Immunoregulation | Hypersensitivity | Chronic infection | Autoantigens | Cell lineage | Lymphocytes T | Inflammatory diseases | Molecular modelling | Reviews | Foxp3 protein | Differentiation | Cancer | Immune system
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