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1. Full Text A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability
by Mercaldo, Valentina and Grant, Seth G N and Zalfa, Francesca and Eleuteri, Boris and De Rubeis, Silvia and Chiurazzi, Pietro and Neri, Giovanni and di Penta, Alessandra and Bagni, Claudia and Dickson, Kirsten S and Tabolacci, Elisabetta
Nature neuroscience, ISSN 1097-6256, 05/2007, Volume 10, Issue 5, pp. 578 - 587
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Disks Large Homolog 4 Protein | Protein Biosynthesis | Embryo, Mammalian | Fragile X Mental Retardation Protein - physiology | Male | Intracellular Signaling Peptides and Proteins - metabolism | RNA, Messenger - metabolism | Tubulin - metabolism | Transfection | Reverse Transcriptase Polymerase Chain Reaction - methods | Membrane Proteins - metabolism | Neurons - metabolism | In Situ Hybridization - methods | Intracellular Signaling Peptides and Proteins - genetics | Cell Survival - physiology | RNA Stability - physiology | Brain - cytology | Immunoprecipitation - methods | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Knockout | Electrophoretic Mobility Shift Assay - methods | Animals | Guanylate Kinases | Fragile X Mental Retardation Protein - genetics | Mice | Care and treatment | Physiological aspects | Genetic aspects | Research | Fragile X syndrome | Binding proteins | Genetic translation | Risk factors | Index Medicus | Fragile X Mental Retardation Protein | ARE | U-rich regions | dendritic mRNA | G-quartet | PSD-95 | mRNA stability
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2. Full Text S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade
by Usha Narayanan and Vijayalaxmi Nalavadi and Mika Nakamoto and George Thomas and Stephanie Ceman and Gary J. Bassell and Stephen T. Warren
The Journal of biological chemistry, ISSN 0021-9258, 07/2008, Volume 283, Issue 27, pp. 18478 - 18482
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Kinases - metabolism | Neurons - pathology | Phosphorylation | Protein Kinases - genetics | Humans | Fragile X Mental Retardation Protein - metabolism | Receptors, Metabotropic Glutamate - metabolism | RNA, Messenger - metabolism | Neuronal Plasticity - genetics | Receptors, Metabotropic Glutamate - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Neurons - metabolism | Protein Biosynthesis - genetics | Fragile X Syndrome - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | RNA, Messenger - genetics | Cells, Cultured | Protein Phosphatase 2 - genetics | Fragile X Syndrome - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Hippocampus - pathology | Signal Transduction - genetics | Nerve Tissue Proteins - genetics | Mice, Knockout | Nerve Tissue Proteins - metabolism | Hippocampus - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Protein Phosphatase 2 - metabolism | Fragile X Mental Retardation Protein - genetics | Mice | TOR Serine-Threonine Kinases | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus
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3. Full Text Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome
by Chen, Eileen and Sharma, Manjuli R and Shi, Xinying and Agrawal, Rajendra K and Joseph, Simpson
Molecular cell, ISSN 1097-2765, 05/2014, Volume 54, Issue 3, pp. 407 - 417
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Ribosomal Proteins - chemistry | Humans | Gene Expression Regulation | Ribosomes - chemistry | Models, Molecular | Ribosomes - metabolism | Fragile X Mental Retardation Protein - physiology | Peptide Chain Initiation, Translational | Drosophila Proteins - chemistry | Drosophila melanogaster - genetics | Ribosomal Proteins - metabolism | Cryoelectron Microscopy | Drosophila melanogaster - metabolism | Drosophila Proteins - physiology | Animals | HEK293 Cells | Fragile X Mental Retardation Protein - chemistry | Protein Binding | G-Quadruplexes | Genetic translation | Mental illness | Mental retardation | Transfer RNA | Protein binding | Index Medicus
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4. Full Text Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
by Ferron, Laurent and Nieto-Rostro, Manuela and Cassidy, John S and Dolphin, Annette C
Nature communications, ISSN 2041-1723, 04/2014, Volume 5, Issue 1, pp. 3628 - 3628
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Line | Synaptic Vesicles - metabolism | Synaptic Transmission - physiology | Calcium - metabolism | Humans | Rats | Fragile X Mental Retardation Protein - metabolism | Calcium Channels, N-Type - metabolism | Exocytosis - physiology | Patch-Clamp Techniques | Animals | Neurons - physiology | Mice | Neurons - metabolism | Index Medicus
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5. Full Text Cellular distribution of the fragile X mental retardation protein in the mouse brain
by Zorio, Diego A.R and Jackson, Christine M and Liu, Yong and Rubel, Edwin W and Wang, Yuan
Journal of comparative neurology (1911), ISSN 0021-9967, 03/2017, Volume 525, Issue 4, pp. 818 - 849
RRID:AB_1157880 | whole brain analyses | fragile X syndrome | RRID:AB_10805421 | subcortical sensory systems | RRID:AB_476743 | cortical laminar heterogeneity | sensory information processing | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Zoology | Science & Technology | Brain - metabolism | Immunohistochemistry | Animals | Transcriptome | Fragile X Syndrome - metabolism | Gene Expression Profiling | Mice | Blotting, Western | Fragile X Mental Retardation Protein - biosynthesis | Mice, Knockout | Brain | Mental retardation | Mental illness | Analysis | Index Medicus | cell-type specificity
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6. Full Text Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development
by Bonaccorso, C.M and Spatuzza, M and Di Marco, B and Gloria, A and Barrancotto, G and Cupo, A and Musumeci, S.A and D’Antoni, S and Bardoni, B and Catania, M.V
International journal of developmental neuroscience, ISSN 0736-5748, 05/2015, Volume 42, Issue 1, pp. 15 - 23
CYFIP2 | CYFIP1 | FXR1P | FMRP | FXR2P | 82-FIP | 82‐FIP | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Animals, Newborn | Age Factors | Microtubule-Associated Proteins - metabolism | Cells, Cultured | Gene Expression Regulation, Developmental - genetics | Fragile X Mental Retardation Protein - metabolism | Brain - growth & development | Hippocampus - cytology | Mice, Knockout | Brain - metabolism | Glial Fibrillary Acidic Protein | Nerve Tissue Proteins - metabolism | Animals | Analysis of Variance | Brain - pathology | Fragile X Mental Retardation Protein - genetics | Mice | Neurons - metabolism | RNA-Binding Proteins - metabolism | Proteins | Mental illness | Index Medicus
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7. Full Text Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD
by Park, Sungjin and Park, Joo Min and Kim, Sangmok and Kim, Jin-Ah and Shepherd, Jason D and Smith-Hicks, Constance L and Chowdhury, Shoaib and Kaufmann, Walter and Kuhl, Dietmar and Ryazanov, Alexey G and Huganir, Richard L and Linden, David J and Worley, Paul F
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2008, Volume 59, Issue 1, pp. 70 - 83
PROTEINS | MOLNEURO | SIGNALING | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Excitatory Postsynaptic Potentials - radiation effects | Protein Biosynthesis - physiology | Fragile X Mental Retardation Protein - physiology | Male | Protein Transport - physiology | Protein Transport - drug effects | Excitatory Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - physiology | Excitatory Amino Acid Agents - pharmacology | Neurons - physiology | Long-Term Potentiation - physiology | Cytoskeletal Proteins - metabolism | Protein Biosynthesis - radiation effects | Protein Synthesis Inhibitors - pharmacology | Electric Stimulation - methods | Animals, Newborn | Receptors, AMPA - physiology | Cells, Cultured | Hippocampus - cytology | Cycloheximide - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Patch-Clamp Techniques | Animals | Peptide Elongation Factor 2 - physiology | Models, Biological | Gene Expression Regulation - radiation effects | Protein Biosynthesis - drug effects | Fragile X Mental Retardation Protein - genetics | Mice | In Vitro Techniques | Dose-Response Relationship, Radiation | Proteins | Studies | Cell culture | Kinases | Protein synthesis | Neurons | Index Medicus
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8. Full Text Fragile X mental retardation protein recognizes a G quadruplex structure within the survival motor neuron domain containing 1 mRNA 5′-UTR
by McAninch, Damian S and Heinaman, Ashley M and Lang, Cara N and Moss, Kathryn R and Bassell, Gary J and Rita Mihailescu, Mihaela and Evans, Timothy L
Molecular bioSystems, ISSN 1742-206X, 2017, Volume 13, Issue 8, pp. 1448 - 1457
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Biosynthesis | Spliceosomes - genetics | Humans | Fragile X Syndrome - pathology | Fragile X Mental Retardation Protein - metabolism | RNA Splicing Factors - chemistry | RNA Splicing Factors - metabolism | Brain - metabolism | Spliceosomes - metabolism | Thermodynamics | Base Sequence | G-Quadruplexes | Transcription, Genetic | Protein Interaction Domains and Motifs | Binding Sites | SMN Complex Proteins - metabolism | Fragile X Syndrome - genetics | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Gene Expression Regulation | Fragile X Syndrome - metabolism | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | RNA Splicing Factors - genetics | Animals | SMN Complex Proteins - chemistry | 5' Untranslated Regions | Brain - pathology | Fragile X Mental Retardation Protein - chemistry | Protein Binding | Brain Chemistry | Fragile X Mental Retardation Protein - genetics | Mice | SMN Complex Proteins - genetics | Index Medicus
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