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Clinical Neurophysiology, ISSN 1388-2457, 2014, Volume 125, Issue 8, pp. 1509 - 1532
.... • In patients with dementia they are useful to demonstrate specific abnormalities in the cerebral cortex circuits... 
Neurology | Intracortical circuitry | Cortical excitability | Differential diagnosis | Motor impairment | Brain stimulation | Neuromodulation | Cognitive dysfunction | LATENCY AFFERENT INHIBITION | MOTOR CORTEX EXCITABILITY | ALZHEIMERS-DISEASE | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | CLINICAL NEUROLOGY | MULTIPLE SYSTEM ATROPHY | IN-VIVO ASSESSMENT | CENTRAL CHOLINERGIC CIRCUITS | PROGRESSIVE SUPRANUCLEAR PALSY | PARKINSONS-DISEASE | Multiple System Atrophy - therapy | Parkinson Disease - therapy | Lewy Body Disease - diagnosis | Humans | Dementia - diagnosis | Acetylcholine - metabolism | Dementia, Vascular - metabolism | Cerebral Cortex - metabolism | Lewy Body Disease - therapy | Alzheimer Disease - diagnosis | Frontotemporal Dementia - metabolism | Dementia - metabolism | Dementia, Vascular - diagnosis | Cognitive Dysfunction - therapy | Multiple System Atrophy - metabolism | Cognitive Dysfunction - diagnosis | Dementia, Vascular - therapy | Parkinson Disease - metabolism | Multiple System Atrophy - diagnosis | Diagnosis, Differential | Cognitive Dysfunction - metabolism | Dementia - therapy | Alzheimer Disease - therapy | Transcranial Magnetic Stimulation - methods | Cognitive Dysfunction - etiology | Frontotemporal Dementia - diagnosis | Supranuclear Palsy, Progressive - therapy | Frontotemporal Dementia - therapy | Lewy Body Disease - metabolism | Dementia - complications | Neuronal Plasticity | Alzheimer Disease - metabolism | Parkinson Disease - diagnosis | Supranuclear Palsy, Progressive - metabolism | Receptors, Neurotransmitter - metabolism | Supranuclear Palsy, Progressive - diagnosis | Diagnosis | Dementia
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 477, Issue 7363, pp. 211 - 215
Journal Article
Acta neuropathologica, ISSN 1432-0533, 2014, Volume 127, Issue 3, pp. 423 - 439
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 51, pp. E4968 - E4977
Journal Article
Journal Article
Nature neuroscience, ISSN 1546-1726, 2012, Volume 15, Issue 11, pp. 1488 - 1497
...) and frontotemporal dementia. We found that FUS/TLS binds to RNAs from >5,500 genes in mouse and human brain, primarily through a GUGGU-binding motif... 
NEURODEGENERATIVE DISEASE | GENE | AMYOTROPHIC-LATERAL-SCLEROSIS | FAMILY PROTEINS | FUS PATHOLOGY | MUTATIONS | FRONTOTEMPORAL LOBAR DEGENERATION | BINDING | NEUROSCIENCES | BRAIN | NASCENT TRANSCRIPTION | RNA, Small Interfering - genetics | Protein Binding - genetics | Oligonucleotide Array Sequence Analysis | Humans | tau Proteins - metabolism | Gene Expression Profiling | RNA, Messenger - metabolism | Kv Channel-Interacting Proteins - metabolism | Brain - metabolism | Frontotemporal Dementia - metabolism | RNA Splicing - genetics | Frontotemporal Dementia - genetics | RNA-Binding Protein FUS - deficiency | Amyotrophic Lateral Sclerosis - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | RNA-Binding Protein FUS - genetics | Mice, Knockout | Motor Neurons - metabolism | Amyotrophic Lateral Sclerosis - pathology | Shal Potassium Channels - metabolism | Brain - pathology | Mice | Neurofilament Proteins - metabolism | RNA, Small Interfering - metabolism | Immunoprecipitation | Spinal Cord - metabolism | DNA-Binding Proteins - deficiency | DNA-Binding Proteins - metabolism | tau Proteins - genetics | Cell Cycle Proteins - genetics | Female | RNA Precursors - metabolism | Excitatory Amino Acid Transporter 2 - genetics | Membrane Proteins - metabolism | Frontotemporal Dementia - pathology | Gene Expression Regulation - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | RNA Precursors - genetics | Protein Structure, Tertiary - genetics | RNA-Binding Protein FUS - metabolism | DNA-Binding Proteins - genetics | Excitatory Amino Acid Transporter 2 - metabolism | Nerve Tissue Proteins - genetics | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Histone-Lysine N-Methyltransferase - metabolism | Amyotrophic Lateral Sclerosis - metabolism | Neural Cell Adhesion Molecules - metabolism | Neural Stem Cells - metabolism | Cell Line, Transformed | Amyotrophic lateral sclerosis | Development and progression | Genetic aspects | Messenger RNA | Health aspects
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, Issue 10047, pp. 919 - 931
Summary Early reports of cognitive and behavioural deficits in motor neuron disease might have been overlooked initially, but the concept of a frontotemporal dementia-motor neuron disease continuum... 
Internal Medicine | HEXANUCLEOTIDE REPEAT EXPANSION | MEDICINE, GENERAL & INTERNAL | PTDP-43 PATHOLOGY | LOBAR DEGENERATION | EXPANDED C9ORF72 | ANTISENSE TRANSCRIPTS | BRAIN NETWORK CONNECTIVITY | C9ORF72 EXPANSION | COGNITIVE IMPAIRMENT | AMYOTROPHIC-LATERAL-SCLEROSIS | RNA FOCI | Neuroimaging | Neuroprotective Agents - therapeutic use | Prognosis | Humans | Patient Care Team | Cognition | Frontotemporal Dementia - psychology | Activities of Daily Living | Brain - metabolism | DNA-Binding Proteins - metabolism | DNA Repeat Expansion | DNA Methylation | Motor Neuron Disease - therapy | Motor Neuron Disease - genetics | Riluzole - therapeutic use | C9orf72 Protein | Executive Function | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | DNA-Binding Proteins - genetics | Frontotemporal Dementia - therapy | Motor Neuron Disease - pathology | Neuropsychological Tests | Proteins - genetics | Proteins - metabolism | Image Processing, Computer-Assisted | Brain - pathology | Motor Neuron Disease - psychology | Mutation | Medical colleges | Neurosciences | Neurons | Epidemiology | Dementia | Protein binding | Brain | Gene expression | Patients | Studies | Pathology | Stem cells | DNA methylation | Epigenetics | Genetics | Chromosomes | Deoxyribonucleic acid--DNA
Journal Article