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Nature, ISSN 0028-0836, 08/2017, Volume 548, Issue 7665, pp. 112 - 116
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 16957 - 9
For protein mutagenesis, a common expectation is that important positions will behave like on/off "toggle" switches (i.e., a few substitutions act like... 
MUTAGENESIS | CONTRIBUTE | PROTEIN | DIRECTED EVOLUTION | MULTIDISCIPLINARY SCIENCES | HYDROXYLATION | Alanine | Allosteric properties | Pyruvate kinase | Mutagenesis | Fructose-1,6-diphosphate | Pyruvic acid | Amino acids | Kinases | Fructose | Binding sites
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 922 - 15
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 05/2018, Volume 237, Issue 2, pp. 101 - 111
Journal Article
by Jeong, GJ and Kang, D and Kim, AK and Han, KH and Jeon, HR and Kim, DI
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6112 - 9
Stem cell therapy has long been considered a promising mode of treatment for many incurable diseases. Human mesenchymal stem cells (hMSCs) have provided the... 
PROLIFERATION | CYCLE PROGRESSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | EXPANSION | PLASTICITY | Cell proliferation | Phosphorylation | Phosphoenolpyruvic acid | Mesenchyme | Oxidative metabolism | Stat3 protein | AKT protein | Metabolism | Fructose | Sodium oxalate | Regeneration | Metabolites | Oxidative phosphorylation | Sodium | Oxalic acid | Fructose-1,6-diphosphate | Stem cells | Glycolysis | Hypoxia
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 9031 - 8
Development of drugs that allosterically regulate enzyme functions to treat disease is a costly venture. Amino acid susbstitutions that mimic allosteric... 
RAT-LIVER | LIVER PYRUVATE-KINASE | MUTAGENESIS | AMINO-ACID-SEQUENCE | PROTEIN | GENE | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | N-TERMINUS | IDENTIFICATION | BINDING | Enzymes | Alanine | Phosphorylation | Pyruvate kinase | Diabetes mellitus | Liver | Pyruvic acid | Amino acids | Genomes | Drug development | Kinases | Fructose | Hyperglycemia | Allosteric properties | Fructose-1,6-diphosphate | Glycolysis | Mutation | Index Medicus
Journal Article
CELL DEATH & DISEASE, ISSN 2041-4889, 09/2019, Volume 10, Issue 10, pp. 1 - 16
Muscle fructose-1,6-bisphosphate aldolase (ALDOA) is among the most abundant glycolytic enzymes in all cancer cells. Here, we show that the enzyme plays a... 
SITE | OXIDATIVE STRESS | ACTIVATION | INHIBITION | ACTIN | OXIDASE | FRUCTOSE-1,6-BISPHOSPHATE | POTASSIUM CHANNELS | SUBCELLULAR-LOCALIZATION | COFILIN | CELL BIOLOGY | Enzymes | Cell survival | Calcium | Mesenchyme | Caspase | Kinases | Fructose | Actin | Fructose-1,6-diphosphate | Glycolysis | Cofilin | Cytoskeleton | Cancer | Apoptosis
Journal Article
Acta Pharmaceutica, ISSN 1330-0075, 06/2015, Volume 65, Issue 2, pp. 147 - 157
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 853 - 15
Journal Article