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1. Full Text The competition between chemistry and biology in assembling iron–sulfur derivatives. Molecular structures and electrochemistry. Part II. {[Fe2S2](SγCys)4} proteins
by Zanello, Piero
Coordination Chemistry Reviews, ISSN 0010-8545, 11/2014, Volume 280, pp. 54 - 83
Redox profiles of [2Fe-2S] ferredoxins of and its truncated form. Since iron–sulfur clusters are often involved in the electron transfer activity of redox... 
Electrochemistry | Biomimetic {[Fe2S2](S-X)4} complexes | [Fe2S2](SγCys)4}proteins | Molecular structures | S | proteins | Biomimetic {[Fe | S-X | complexes | Fe | RESPIRATORY COMPLEX-I | PLANT-TYPE FERREDOXINS | Biomimetic {[Fe2S2](S-X)} complexes | [Fe2S2](S-Cys(gamma))}proteins | SOLUBLE METHANE MONOOXYGENASE | SITE-DIRECTED MUTAGENESIS | 2FE-2S FERREDOXIN-I | NADP-REDUCING HYDROGENASE | CHEMISTRY, INORGANIC & NUCLEAR | COLI FUMARATE REDUCTASE | AMINO-ACID-RESIDUES | OXIDATION-REDUCTION POTENTIALS | PHTHALATE DIOXYGENASE REDUCTASE | Sulfur compounds | Electrochemical reactions | Iron proteins
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2. Full Text Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering
by Lalwani, Gaurav and Henslee, Allan M and Farshid, Behzad and Lin, Liangjun and Kasper, F. Kurtis and Qin, Yi-Xian and Mikos, Antonios G and Sitharaman, Balaji
Biomacromolecules, ISSN 1525-7797, 03/2013, Volume 14, Issue 3, pp. 900 - 909
This study investigates the efficacy of two-dimensional (2D) carbon and inorganic nanostructures as reinforcing agents for cross-linked composites of the... 
CORTICAL BONE | GRAPHENE NANORIBBONS | POLYMER SCIENCE | ELASTIC PROPERTIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | LAYER MOS2 | CHEMISTRY, ORGANIC | NANOSHEETS | COMPOSITES | WALLED CARBON NANOTUBES | MECHANICAL-PROPERTIES | CANCELLOUS BONE | FABRICATION | Compressive Strength | Microscopy, Electron, Transmission | Tissue Engineering - methods | Bone and Bones - chemistry | Nanocomposites - chemistry | Nanotubes, Carbon - chemistry | Biocompatible Materials - chemistry | Humans | Composite Resins - chemistry | Fumarates - chemistry | Polymers - chemistry | Polypropylenes - chemistry | Index Medicus
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3. Full Text Multifunctional organoboron compounds for scalable natural product synthesis
by Meng, Fanke and Meng, Fanke and McGrath, Kevin P and McGrath, Kevin P and Hoveyda, Amir H and Hoveyda, Amir H
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7518, pp. 367 - 374
Efficient catalytic reactions that can generate C-C bonds enantioselectively, and ones that can produce trisubstituted alkenes diastereoselectively, are... 
ORGANIC-SYNTHESIS | CYCLIC ENONES | REAGENTS | ENANTIOSELECTIVE SYNTHESIS | FUMARATE REDUCTASE INHIBITOR | MULTIDISCIPLINARY SCIENCES | CU-CATALYZED HYDROBORATION | NHC LIGANDS | CONJUGATE ADDITIONS | EFFICIENT | CARBON STEREOGENIC CENTERS | Monosaccharides - chemical synthesis | Pyrans - chemical synthesis | Boron - chemistry | Stereoisomerism | Antineoplastic Agents - chemical synthesis | Fatty Alcohols - chemical synthesis | Fatty Alcohols - chemistry | Alkenes - chemical synthesis | Antineoplastic Agents - chemistry | Anti-Bacterial Agents - chemical synthesis | Alkenes - chemistry | Biological Products - chemical synthesis | Biological Products - chemistry | Animals | Copper - chemistry | Pyrans - chemistry | Anti-Bacterial Agents - chemistry | Catalysis | Porifera - chemistry | Monosaccharides - chemistry | Usage | Natural products | Chemical properties | Chemical synthesis | Organoboron compounds | Methods | Production processes | Phosphates | Boron | Index Medicus
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4. Full Text Composition of Sugars, Organic Acids, and Total Phenolics in 25 Wild or Cultivated Berry Species
by Mikulic‐Petkovsek, Maja and Schmitzer, Valentina and Slatnar, Ana and Stampar, Franci and Veberic, Robert
Journal of Food Science, ISSN 0022-1147, 10/2012, Volume 77, Issue 10, pp. C1064 - C1070
Sugars, organic acids, and total phenolic content in fruit of 25 wild and cultivated berry species were identified and quantified with high‐performance liquid... 
wild berry species | sugars | total phenolics | fruit quality | organic acids | Total phenolics | Wild berry species | Fruit quality | Organic acids | Sugars | MORUS-NIGRA | QUALITY | APPLE CULTIVARS | FOOD SCIENCE & TECHNOLOGY | TASTE | PARAMETERS | ANTIOXIDANT PROPERTIES | FRUIT | BLACK | HEALTH | Sorbus - chemistry | Vaccinium macrocarpon - chemistry | Sambucus - chemistry | Fruit - chemistry | Tartrates - analysis | Chromatography, High Pressure Liquid | Actinidia - chemistry | Rosaceae - chemistry | Malates - analysis | Plant Extracts - analysis | Fumarates - analysis | Phenols - analysis | Ribes - chemistry | Carbohydrates - analysis | Photinia - chemistry | Fragaria - chemistry | Citric Acid - analysis | Shikimic Acid - analysis | Composition | Usage | Berries | Phenols | Liquid chromatography | Chemical properties | Food science | Glucose | Phenology | Chromatography | Sugar | Index Medicus | Sorbitol | Liquids | Kiwifruit | Citric acid | Fruits
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5. Full Text Salt and cocrystals of sildenafil with dicarboxylic acids: Solubility and pharmacokinetic advantage of the glutarate salt
by Sanphui, Palash and Tothadi, Srinu and Ganguly, Somnath and Desiraju, Gautam R
Molecular Pharmaceutics, ISSN 1543-8384, 12/2013, Volume 10, Issue 12, pp. 4687 - 4697
Sildenafil is a drug used to treat erectile dysfunction and pulmonary arterial hypertension. Because of poor aqueous solubility of the drug, the citrate salt,... 
X-ray crystallography | bioavailability | crystal engineering | dissolution | hydrogen bond | DRUG | MEDICINE, RESEARCH & EXPERIMENTAL | IMPROVE | HYDROGEN-BONDS | FORMS | crystal engineering X-ray crystallography | ORAL BIOAVAILABILITY | SUPRAMOLECULAR HETEROSYNTHONS | PHARMACOLOGY & PHARMACY | ACTIVE PHARMACEUTICAL INGREDIENTS | CRYSTALLINE SOLIDS | CARBOXYLIC-ACIDS | WATER | Dicarboxylic Acids - pharmacokinetics | Area Under Curve | Biological Availability | Male | Piperazines - chemistry | Pimelic Acids - pharmacokinetics | Salts - chemistry | Sildenafil Citrate | Glutarates - pharmacokinetics | Sulfones - chemistry | Oxalic Acid - pharmacokinetics | Water - chemistry | Salts - pharmacokinetics | Glutarates - chemistry | Pimelic Acids - chemistry | Piperazines - pharmacokinetics | Oxalic Acid - chemistry | Purines - pharmacokinetics | Crystallization | Solubility | Fumarates - chemistry | Rats | Succinic Acid - pharmacokinetics | Permeability | Sulfones - pharmacokinetics | Rats, Sprague-Dawley | Dicarboxylic Acids - chemistry | Animals | Purines - chemistry | Fumarates - pharmacokinetics | Succinic Acid - chemistry | Index Medicus
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6. Full Text Proton transfer and hydrogen bonding in the organic solid state: A combined XRD/XPS/ssNMR study of 17 organic acid-base complexes
by Stevens, Joanna S and Byard, Stephen J and Seaton, Colin C and Sadiq, Ghazala and Davey, Roger J and Schroeder, Sven L. M
Physical Chemistry Chemical Physics, ISSN 1463-9076, 01/2014, Volume 16, Issue 3, pp. 1150 - 1160
The properties of nitrogen centres acting either as hydrogen-bond or Bronsted acceptors in solid molecular acid-base complexes have been probed by N 1s X-ray... 
CRYSTAL NEUTRON-DIFFRACTION | DICARBOXYLIC-ACIDS | CO-CRYSTAL | NMR | TEMPERATURE-DEPENDENCE | CHEMICAL-SHIFTS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | RAY PHOTOELECTRON-SPECTROSCOPY | X-RAY | CHEMISTRY, PHYSICAL | COCRYSTAL | CARBOXYLIC-ACIDS | Protons | Oxalic Acid - chemistry | Benzoates - chemistry | Fumarates - chemistry | Models, Molecular | Crystallography, X-Ray | Salicylates - chemistry | Citric Acid - chemistry | Quantum Theory | Benzenesulfonates - chemistry | Hydrogen Bonding | Malonates - chemistry | X-Rays | Hydrochloric Acid - chemistry | Glutarates - chemistry | Molecular Structure | Spectrophotometry | Index Medicus | Correlation | Diffraction | Molecular structure | X-rays | X-ray diffraction | Nuclear magnetic resonance | X-ray photoelectron spectroscopy | Crystal structure
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7. Full Text Influence of chitosan swelling behaviour on controlled release of tenofovir from mucoadhesive vaginal systems for prevention of sexual transmission of HIV
by Notario-Pérez, Fernando and Martín-Illana, Araceli and Cazorla-Luna, Raúl and Ruiz-Caro, Roberto and Bedoya, Luis-Miguel and Tamayo, Aitana and Rubio, Juan and Veiga, María-Dolores
Marine Drugs, ISSN 1660-3397, 02/2017, Volume 15, Issue 2, pp. 50 - 50
The main challenges facing efforts to prevent the transmission of human immunodeficiency virus (HIV) are the lack of access to sexual education services and... 
Tenofovir | Swelling behaviour | Acquired immunodeficiency syndrome | Chitosan | Human immunodeficiency virus | Ex vivo bioadhesion | Mucoadhesive vaginal tablets | Controlled release | Swelling witness microstructure | chitosan | DESIGN | CHEMISTRY, MEDICINAL | Human Immunodeficiency Virus | swelling behaviour | DRUG-RELEASE | CLOTRIMAZOLE | FORMULATION | DELIVERY | GEL | ex vivo bioadhesion | MATRIX TABLETS | controlled release | IN-VITRO EVALUATION | Acquired Immunodeficiency Syndrome | swelling witness microstructure | DISOPROXIL FUMARATE | INTRAVAGINAL RING | mucoadhesive vaginal tablets | Galactans - chemistry | HIV Infections - prevention & control | Chemistry, Pharmaceutical - methods | Hypromellose Derivatives - chemistry | Vagina - drug effects | Humans | Tenofovir - pharmacology | Tenofovir - chemistry | Delayed-Action Preparations - chemistry | Tablets - pharmacology | Sexually Transmitted Diseases - prevention & control | Adhesives - chemistry | Mannans - chemistry | Cattle | Delayed-Action Preparations - pharmacology | Female | Mucous Membrane - drug effects | Cell Line | Adhesives - pharmacology | Plant Gums - chemistry | Acrylic Resins - chemistry | Animals | Chitosan - chemistry | Tablets - chemistry | Polymers - chemistry | Drug Delivery Systems - methods | Index Medicus
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8. Full Text Assessing the chiral switch: Approval and use of single-enantiomer drugs, 2001 to 2011
by Gellad, Walid F and Choi, Phillip and Mizah, Margaret and Good, Chester B and Kesselheim, Aaron S
American Journal of Managed Care, ISSN 1088-0224, 2014, Volume 20, Issue 3, pp. e90 - e97
Objectives: A "chiral switch" occurs in the pharmaceutical market when a drug made up of 2 enantiomer forms is replaced with a purified single-enantiomer... 
MEDICATION | NAMES | MULTICENTER | EROSIVE ESOPHAGITIS | OMEPRAZOLE | RANDOMIZED CONTROLLED-TRIAL | 8-WEEK COMPARATIVE TRIAL | MEDICINE, GENERAL & INTERNAL | COST | HEALTH CARE SCIENCES & SERVICES | DOUBLE-BLIND | HEALTH POLICY & SERVICES | HEALTH | Proton Pump Inhibitors - economics | Formoterol Fumarate | Hypnotics and Sedatives - chemistry | Medicaid - economics | Stereoisomerism | United States | Humans | Dexmethylphenidate Hydrochloride - chemistry | Drugs, Generic - economics | Piperazines - economics | Esomeprazole - chemistry | Drug Approval | Piperazines - chemistry | Esomeprazole - economics | Eszopiclone | Azabicyclo Compounds - chemistry | Benzhydryl Compounds - chemistry | Antidotes - economics | Bronchodilator Agents - chemistry | Levoleucovorin - chemistry | Histamine H1 Antagonists, Non-Sedating - economics | Dexmethylphenidate Hydrochloride - economics | Dexlansoprazole - chemistry | Retrospective Studies | Central Nervous System Stimulants - economics | United States Food and Drug Administration | Wakefulness-Promoting Agents - chemistry | Levoleucovorin - economics | Antidotes - chemistry | Bronchodilator Agents - economics | Azabicyclo Compounds - economics | Benzhydryl Compounds - economics | Cetirizine - chemistry | Cetirizine - economics | Ethanolamines - economics | Ethanolamines - chemistry | Patents as Topic | Hypnotics and Sedatives - economics | Wakefulness-Promoting Agents - economics | Drug Prescriptions - statistics & numerical data | Proton Pump Inhibitors - chemistry | Central Nervous System Stimulants - chemistry | Dexlansoprazole - economics | Histamine H1 Antagonists, Non-Sedating - chemistry | Clinical trials | Prescription drugs | Trends | Comparative analysis | Health administration
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9. Full Text Influence of Trace Elements on Stabilization of Aqueous Solutions of Ascorbic Acid
by Dolińska, Barbara and Ostróżka-Cieślik, Aneta and Caban, Artur and Rimantas, Klimas and Leszczyńska, Lucyna and Ryszka, Florian
Biological Trace Element Research, ISSN 0163-4984, 12/2012, Volume 150, Issue 1, pp. 509 - 512
Together with vitamin C, zinc, selenium, manganese, and magnesium play a vital role in the preservation of organs scheduled for transplantation. In the present... 
Life Sciences | Biochemistry, general | Biotechnology | Microelements | Nutrition | Solutions | Preservation | Vitamin C | Oncology | Accelerated stability test | OXIDATIVE STRESS | ANTIOXIDANTS | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRESERVATION SOLUTIONS | SELENIUM | ENDOCRINOLOGY & METABOLISM | PERFUSION | KIDNEY | Selenium - chemistry | Zinc Acetate - chemistry | Antioxidants - chemistry | Ascorbic Acid - analysis | Oxidation-Reduction | Drug Stability | Trace Elements - chemistry | Fumarates - chemistry | Hot Temperature | Manganese - chemistry | Zinc - chemistry | Preservatives, Pharmaceutical - chemistry | Magnesium - chemistry | Osmolar Concentration | Organ Preservation Solutions - chemistry | Sulfates - chemistry | Ascorbic Acid - chemistry | Sodium Selenite - chemistry | Kinetics | Antioxidants - analysis | Manganese Compounds - chemistry | Aqueous solutions | Trace elements | Index Medicus
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10. Full Text Isolation of mitochondria, their sub-organellar compartments, and membranes
by Duncan, Owen and Harvey Millar, A and Taylor, Nicolas L
Methods in Molecular Biology, ISSN 1064-3745, 2017, Volume 1511, pp. 83 - 96
Mitochondria are the sites of a diverse set of essential biochemical processes in plants. In order to facilitate the analysis of these functions, this chapter... 
Mitochondria | Matrix | Arabidopsis | Protoplast | Intermembrane space | Solanacea | Subfractionation | Arabidopsis - chemistry | Phosphotransferases (Alcohol Group Acceptor) - chemistry | Silicon Dioxide - chemistry | Cell Fractionation - methods | Fumarate Hydratase - chemistry | Enzyme Assays | Intracellular Membranes - chemistry | Mitochondria - ultrastructure | Intracellular Membranes - ultrastructure | Aconitate Hydratase - chemistry | Povidone - chemistry | Arabidopsis Proteins - chemistry | Protoplasts - ultrastructure | Centrifugation, Density Gradient - methods | Kinetics | Protoplasts - chemistry | Culture Media - chemistry | Mitochondria - chemistry | Peroxisomes - chemistry | Biomarkers - chemistry | Centrifugation, Density Gradient - instrumentation | Peroxisomes - ultrastructure | Catalase - chemistry | Cell Fractionation - instrumentation | Index Medicus
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11. Full Text Alginate based hybrid copolymer hydrogels—Influence of pore morphology on cell–material interaction
by Gnanaprakasam Thankam, Finosh and Muthu, Jayabalan
Carbohydrate Polymers, ISSN 0144-8617, 11/2014, Volume 112, pp. 235 - 244
Alginate based hybrid copolymer hydrogels with unidirectional pore morphology were prepared to achieve synergistic biological performance for cardiac tissue... 
Alginate hybrid copolymer | Physical properties | Cell–material interaction | Morphologically modified hydrogels | Cell-material interaction | MIGRATION | ELASTOMER | POLYMER SCIENCE | TISSUE | SIZE | VIABILITY | CHEMISTRY, ORGANIC | PROLIFERATION | ARTICULAR-CARTILAGE | 3D SCAFFOLDS | GROWTH | CHEMISTRY, APPLIED | POLYMER SCAFFOLDS | Cell Proliferation | Cross-Linking Reagents - chemistry | Tissue Engineering - methods | Myocytes, Cardiac - cytology | Fumarates - chemistry | Polyethylene Glycols - chemistry | Hexuronic Acids - chemistry | Acrylamides - chemistry | Biocompatible Materials - chemical synthesis | Collagen - metabolism | Animals | Spectrophotometry, Infrared | Alginates - chemistry | Surface Properties | Polymers - chemistry | Polypropylenes - chemistry | Fibroblasts - cytology | Mice | Glucuronic Acid - chemistry | Hydrogels - chemistry | Index Medicus
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12. Full Text Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering
by Park, Hansoo and Temenoff, Johnna S and Tabata, Yasuhiko and Caplan, Arnold I and Mikos, Antonios G
Biomaterials, ISSN 0142-9612, 2007, Volume 28, Issue 21, pp. 3217 - 3227
Abstract We investigated the development of an injectable, biodegradable hydrogel composite of oligo(poly(ethylene glycol) fumarate) (OPF) with encapsulated... 
Advanced Basic Science | Dentistry | Cartilage tissue engineering | Marrow mesenchymal stem cells | Injectable hydrogels | Tgf- β1 | Gelatin microparticles | Tgf-β1 | cartilage tissue engineering | PHOTOENCAPSULATION | MACROMER | MATERIALS SCIENCE, BIOMATERIALS | injectable hydrogels | CHONDROCYTES | ENGINEERING, BIOMEDICAL | REGENERATION | BONE-MARROW | Tgf-beta 1 | OSTEOGENIC DIFFERENTIATION | NETWORKS | RELEASE | marrow mesenchymal stem cells | GLYCOL) FUMARATE) HYDROGELS | IN-VITRO | gelatin microparticles | Chondrocytes - cytology | Transforming Growth Factor beta1 - administration & dosage | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Microinjections - methods | Titanium - chemistry | Polyethylene Glycols - chemistry | Collagen Type II - metabolism | Dose-Response Relationship, Drug | Nanoparticles | Chondrocytes - drug effects | Transforming Growth Factor beta1 - chemistry | Mesenchymal Stromal Cells - cytology | Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage | Time Factors | Surface Properties | Gelatin - chemistry | Mesenchymal Stromal Cells - physiology | Transforming Growth Factor beta1 - pharmacology | Glycosaminoglycans - biosynthesis | Cell Survival - drug effects | Rabbits | Gene Expression | Cross-Linking Reagents - chemistry | Tissue Engineering - methods | Peptides - chemistry | Bone Marrow Cells - cytology | Cells, Cultured | Coated Materials, Biocompatible - chemistry | Fumarates - chemistry | Aggrecans - metabolism | Cartilage - metabolism | Aggrecans - genetics | Collagen Type II - genetics | Absorbable Implants | Particle Size | Animals | Cell Adhesion - physiology | Cell Differentiation - drug effects | Polymers - chemistry | Cell Proliferation - drug effects | Composite materials industry | Gene expression | Biopolymers | Stem cells | Index Medicus | TGF-β1
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13. Full Text Poly(propylene fumarate)/Polyethylene Glycol-Modified Graphene Oxide Nanocomposites for Tissue Engineering
by Díez-Pascual, Ana M and Díez-Vicente, Angel L
ACS Applied Materials and Interfaces, ISSN 1944-8244, 07/2016, Volume 8, Issue 28, pp. 17902 - 17914
Poly(propylene fumarate) (PPF)-based nanocomposites incorporating different amounts of polyethylene glycol-functionalized graphene oxide (PEG-GO) have been... 
graphene oxide | polyethylene glycol | tissue engineering | nanocomposites | mechanical properties | poly(propylene fumarate) | FUMARATE | PHYSICAL-PROPERTIES | CELL RESPONSES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CROSS-LINKING | NANOSHEETS | NANOSCIENCE & NANOTECHNOLOGY | MECHANICAL-PROPERTIES | IN-VITRO DEGRADATION | BIOMEDICAL APPLICATIONS | BONE | FUNCTIONALIZED GRAPHENE | Nanocomposites - chemistry | Biocompatible Materials - chemistry | Escherichia coli - drug effects | Humans | Oxides - chemistry | Cell Growth Processes - physiology | Polyethylene Glycols - chemistry | Anti-Bacterial Agents - chemistry | Graphite - chemistry | Graphite - pharmacology | Bone and Bones - cytology | Polyethylene Glycols - pharmacology | Propylene Glycols - pharmacology | Tissue Engineering - methods | Fumarates - chemistry | Biocompatible Materials - pharmacology | Pseudomonas aeruginosa - drug effects | Oxides - pharmacology | Tissue Engineering - instrumentation | Fibroblasts - drug effects | Fumarates - pharmacology | Polymers - pharmacology | Propylene Glycols - chemistry | Polymers - chemistry | Anti-Bacterial Agents - pharmacology | Staphylococcus aureus - drug effects | Index Medicus
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14. Full Text Cosuspensions of microcrystals and engineered microparticles for uniform and efficient delivery of respiratory therapeutics from pressurized metered dose inhalers
by Vehring, Reinhard and Lechuga-Ballesteros, David and Joshi, Vidya and Noga, Brian and Dwivedi, Sarvajna K
Langmuir, ISSN 0743-7463, 10/2012, Volume 28, Issue 42, pp. 15015 - 15023
Engineered porous phospholipid microparticles with aerodynamic diameters in the respirable range of 1-2 mu m were cosuspended in 1,1,1,2-tetrafluoroethane, a... 
FORMOTEROL | FORMULATIONS | COMBINATION THERAPY | PERFORMANCE | MATERIALS SCIENCE, MULTIDISCIPLINARY | DISEASE | PMDI | CHEMISTRY, PHYSICAL | ASTHMA | CHEMISTRY, MULTIDISCIPLINARY | COPD | Formoterol Fumarate | Solubility | Fumarates - chemistry | Phospholipids - chemistry |