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Journal Article
AIDS, ISSN 0269-9370, 01/2014, Volume 28, Issue 1, pp. 59 - 66
Journal Article
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2018, Volume 103, Issue 2, pp. 341 - 348
Journal Article
HIV Medicine, ISSN 1464-2662, 09/2015, Volume 16, Issue 8, pp. 502 - 511
Journal Article
JAIDS Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 08/2018, Volume 78, Issue 4, pp. 465 - 472
BACKGROUND:Tenofovir alafenamide (TAF), a prodrug of the nucleotide analogue tenofovir (TFV), is an antiretroviral (ARV) agent approved either as a complete... 
INFECTIOUS DISEASES | ELVITEGRAVIR | antiretroviral therapy | VIRALLY SUPPRESSED ADULTS | EMTRICITABINE | OPEN-LABEL | IMMUNOLOGY | P-GLYCOPROTEIN | PHASE 3B | NON-INFERIORITY | DISOPROXIL FUMARATE | pharmacokinetics | TAF | DOUBLE-BLIND | INFECTED PATIENTS | drug-drug interaction
Journal Article
Journal Article
The Journal of antimicrobial chemotherapy, ISSN 0305-7453, 06/2019, Volume 74, Issue 6, pp. 1670 - 1678
Objectives: Tenofovir alafenamide produces lower plasma tenofovir and higher intracellular tenofovir diphosphate (DP) concentrations than tenofovir disoproxil... 
INFECTIOUS DISEASES | ACTIVATION | THERAPY | PRODRUG | SAFETY | DISOPROXIL FUMARATE | GS-7340 | MICROBIOLOGY | PHARMACOLOGY & PHARMACY
Journal Article
Respiratory Medicine, ISSN 0954-6111, 05/2018, Volume 138, pp. 74 - 80
This study compared the efficacy, pharmacokinetics (PK), and safety of GFF MDI (Bevespi Aerosphere ), a fixed-dose combination of glycopyrronium and formoterol... 
Co-suspension delivery technology | Metered dose inhaler | Formoterol fumarate dihydrate | Spacer | Valved holding chamber | Glycopyrronium | LUNG | CARDIAC & CARDIOVASCULAR SYSTEMS | CO-SUSPENSION(TM) DELIVERY TECHNOLOGY | DEPOSITION | COMBINATION | CHILDREN | RESPIRATORY SYSTEM | SPACER DEVICES | ASTHMA | COPD | Bronchodilator Agents - blood | Bronchodilator Agents - administration & dosage | Forced Expiratory Volume - drug effects | Humans | Middle Aged | Muscarinic Antagonists - adverse effects | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Pulmonary Disease, Chronic Obstructive - blood | Metered Dose Inhalers | Female | Bronchodilator Agents - adverse effects | Muscarinic Antagonists - blood | Formoterol Fumarate - blood | Glycopyrrolate - adverse effects | Severity of Illness Index | Inhalation Spacers | Formoterol Fumarate - adverse effects | Glycopyrrolate - blood | Muscarinic Antagonists - administration & dosage | Glycopyrrolate - administration & dosage | Aged | Drug Combinations | Formoterol Fumarate - administration & dosage | Pulmonary Disease, Chronic Obstructive - drug therapy | Chlorofluorocarbons | Parameters | Lung diseases | Pharmacology | Glycopyrrolate | Patients | Confidence intervals | Randomization | Concentration time | Obstructive lung disease | Formoterol | Chronic obstructive pulmonary disease | Safety | Pharmacokinetics | Drug dosages
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 11/2008, Volume 48, Issue 11, pp. 1323 - 1338
This study investigated the potential pharmacokinetic interaction between the direct renin inhibitor aliskiren and modulators of P‐glycoprotein and cytochrome... 
direct renin inhibitor | P‐glycoprotein | Cytochrome P450 | drug interaction | P-glycoprotein | Direct renin inhibitor | Drug interaction | TRANSPORTER | VOLUNTEERS | PHARMACODYNAMICS | ITRACONAZOLE | CLINICAL PHARMACOKINETICS | IN-VITRO | PHARMACOLOGY & PHARMACY | ABSORPTION | 1,4-DIHYDROPYRIDINE CALCIUM-ANTAGONISTS | HYPERTENSION | DRUG-DRUG INTERACTIONS | Antifungal Agents - adverse effects | Digoxin - adverse effects | Pyrroles - pharmacokinetics | Heptanoic Acids - pharmacokinetics | Humans | Male | Heptanoic Acids - adverse effects | Organic Anion Transporters - metabolism | Tissue Distribution | Young Adult | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Drug Interactions | Antifungal Agents - pharmacokinetics | Amides - adverse effects | Amides - pharmacokinetics | Pyrroles - adverse effects | Adult | Female | Caco-2 Cells | Cell Line | Ketoconazole - pharmacokinetics | Fumarates - adverse effects | Digoxin - pharmacokinetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Renin - antagonists & inhibitors | Cytochrome P-450 CYP3A - metabolism | Fumarates - pharmacokinetics | Atorvastatin | Ketoconazole - adverse effects | Antihypertensive drugs | Dosage and administration | Glycoproteins | Research | Drug interactions | Cytochrome P-450 | Index Medicus
Journal Article
Journal Article