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Immunity (Cambridge, Mass.), ISSN 1074-7613, 2015, Volume 43, Issue 3, pp. 475 - 487
.../Enhancer Binding Protein (C/EBP), and Mitogen Activated Protein Kinase (MAPK) pathways. IL-17-induced targets include cytokines (IL-6, G-CSF), antimicrobial peptides... 
negative regulation | Regnase-1 | fungal immunity | autoimmunity | signal transduction | IL-17 | Autoimmunity | Signal transduction | Fungal immunity | Negative regulation | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IL-17 RECEPTOR | TARGET GENES | CANDIDA-ALBICANS | C/EBP-BETA | GENE-EXPRESSION | HOST-DEFENSE | NECROSIS-FACTOR-ALPHA | MESSENGER-RNA STABILITY | T-CELL | IMMUNOLOGY | Candidiasis - genetics | Oncogene Proteins - genetics | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Immunoblotting | Male | Receptors, Interleukin-17 - genetics | Ribonucleases - metabolism | Host-Pathogen Interactions - immunology | Inflammation - metabolism | Lipocalins - genetics | Adaptor Proteins, Signal Transducing - immunology | Pneumonia - immunology | Candida albicans - physiology | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Pneumonia - genetics | Interleukin-6 - genetics | Oncogene Proteins - metabolism | Signal Transduction - genetics | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Lipocalin-2 | Lipocalins - immunology | Interleukin-6 - immunology | Pneumonia - metabolism | Ribonucleases - genetics | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Acute-Phase Proteins - genetics | Candidiasis - microbiology | Signal Transduction - immunology | HEK293 Cells | Female | Candidiasis - immunology | Nuclear Proteins - genetics | Oncogene Proteins - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Nuclear Proteins - immunology | Animals | Ribonucleases - immunology | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Adaptor Proteins, Signal Transducing - metabolism | Acute-Phase Proteins - immunology | Medical colleges | Nucleases | Interleukins | RNA | Cellular signal transduction | Inflammation | Proteins | Cytokines | Rodents | Fibroblasts | Infections | Kinases | Laboratory animals | Gene expression | Experiments
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 41, pp. 34149 - 34156
Dectin-1 is a pattern recognition receptor that is important for innate immune responses against fungi in humans and mice. Dectin-1 binds to beta-glucans in... 
YEAST | CELLS | RESPONSES | PHAGOCYTOSIS | ACTIVATION | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-GLUCAN RECOGNITION | RECEPTOR | AUTOPHAGY | DECTIN-1 | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Protein-Tyrosine Kinases - metabolism | Dendritic Cells - immunology | Lectins, C-Type - immunology | NADPH Oxidases - immunology | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Lectins, C-Type - genetics | Enzyme Activation - immunology | Protein-Tyrosine Kinases - immunology | CD4-Positive T-Lymphocytes - immunology | Lectins, C-Type - metabolism | Phagosomes - immunology | Protein-Tyrosine Kinases - genetics | Bone Marrow Cells - immunology | NADPH Oxidases - genetics | Histocompatibility Antigens Class II - metabolism | beta-Glucans - immunology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Macrophages - immunology | Cell Line | Bone Marrow Cells - cytology | Antigens, Fungal - metabolism | CD4-Positive T-Lymphocytes - cytology | Phagosomes - metabolism | CD4-Positive T-Lymphocytes - metabolism | Antigens, Fungal - immunology | Macrophages - cytology | Mice, Knockout | Microtubule-Associated Proteins - immunology | beta-Glucans - metabolism | Animals | Histocompatibility Antigens Class II - immunology | Autophagy-Related Protein 5 | Protein Binding | Dendritic Cells - cytology | Mice | Histocompatibility Antigens Class II - genetics | Enzyme Activation - genetics | Antigen Presentation - physiology | Phagosomes - genetics | Lectin | Dectin-1 | Immunology | Dendritic Cells | Innate Immunity | Macrophages | Phagocytosis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 17, pp. 5533 - 5538
...). A gene encoding a fungal PG was fused with a gene encoding a plant polygalacturonase-inhibiting protein (PGIP... 
PGIP | Polygalacturonase | Oligogalacturonides | Plant immunity | DAMPs | POLYGALACTURONASE-INHIBITING PROTEIN | ARABIDOPSIS-THALIANA | DEFENSE RESPONSES | BOTRYTIS-CINEREA | MULTIDISCIPLINARY SCIENCES | TRANSLATIONAL INHIBITION | oligogalacturonides | SALICYLIC-ACID | SIGNALING PATHWAY | ELICITORS | polygalacturonase | RESISTANCE | HOST-PATHOGEN INTERACTIONS | plant immunity | Recombinant Fusion Proteins - immunology | Plant Immunity | Fungal Proteins - biosynthesis | Pseudomonas syringae - growth & development | Plant Diseases - immunology | Polygalacturonase - immunology | Arabidopsis - immunology | Plant Diseases - microbiology | Fungal Proteins - immunology | Arabidopsis Proteins - biosynthesis | Hexuronic Acids - immunology | Plant Diseases - genetics | Polygalacturonase - genetics | Pectobacterium carotovorum - growth & development | Botrytis - immunology | Botrytis - growth & development | Pectobacterium carotovorum - immunology | Recombinant Fusion Proteins - biosynthesis | Arabidopsis Proteins - genetics | Pseudomonas syringae - immunology | Mice, Transgenic | Plant Proteins - immunology | Fungal Proteins - genetics | Arabidopsis Proteins - immunology | Arabidopsis - metabolism | Arabidopsis - genetics | Arabidopsis - microbiology | Plant Proteins - genetics | Polygalacturonase - biosynthesis | Animals | Recombinant Fusion Proteins - genetics | Plant Proteins - biosynthesis | Hexuronic Acids - metabolism | Enzymes | Botanical research | Pectin | Disease susceptibility | Regulation | Research | Properties | Gene expression | Observations | Biological Sciences
Journal Article
PLoS pathogens, ISSN 1553-7374, 2011, Volume 7, Issue 7, pp. e1002148 - 17
Wounded leaves of Arabidopsis thaliana show transient immunity to Botrytis cinerea, the causal agent of grey mould. Using a fluorescent probe, histological... 
APPRESSORIUM FORMATION | TOMATO LEAVES | OXIDATIVE STRESS | OXALIC-ACID | BOTRYTIS-CINEREA | MICROBIOLOGY | CHEMICAL SIGNALS | CUTINASE | VIROLOGY | F-SP PISI | HYDROGEN-PEROXIDE | ABSCISIC-ACID | PARASITOLOGY | Coenzyme A Ligases - genetics | Membrane Lipids - genetics | Plant Diseases - immunology | Arabidopsis - immunology | Coenzyme A Ligases - immunology | Plant Diseases - microbiology | Carboxy-Lyases - genetics | Mutation - immunology | Superoxides - immunology | Plant Diseases - genetics | Botrytis - immunology | Membrane Lipids - immunology | Arabidopsis Proteins - genetics | Plants, Genetically Modified - genetics | Plants, Genetically Modified - immunology | Fungal Proteins - genetics | Plant Immunity - physiology | Arabidopsis Proteins - immunology | Plant Leaves - immunology | Arabidopsis - microbiology | Plants, Genetically Modified - microbiology | Plant Leaves - genetics | Hydrogen Peroxide - immunology | Abscisic Acid - immunology | Carboxy-Lyases - immunology | Abscisic Acid - genetics | Trametes - genetics | Plant Leaves - microbiology | Fungal Proteins - metabolism | Arabidopsis thaliana | Physiological aspects | Reactive oxygen species | Immune response | Research | Permeability | Leaves | Humidity | Abscisic acid | ABC transporters | Biosynthesis | Flowers & plants | Gene expression | Fatty acids | Experiments | Fruits | Life Sciences
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 3, pp. 598 - 608
... acids, lipids, and proteins. Recent years have seen a tremendous acceleration of knowledge in the field of glycobiology, revealing many intricacies and functional contributions that were previously poorly appreciated or even unrecognized... 
Allergy and Immunology | glycan | treatment | glycan-binding proteins | Siglec | selectin | dectin | sialic acid | glycobiology | ANTIINFLAMMATORY ACTIVITY | HUMAN-EOSINOPHIL APOPTOSIS | IMMUNOLOGY | FUNGAL-INFECTIONS | ALLERGY | IN-VIVO | INHIBITORY RECEPTOR | HUMAN MAST-CELLS | INTRAVENOUS IMMUNOGLOBULIN PREPARATIONS | CD33-RELATED SIGLECS | B-CELL TOLERANCE | TARGETED DELIVERY | Inflammation - pathology | Humans | Selectins - genetics | Selectins - immunology | Hypersensitivity - immunology | Selectins - chemistry | Sialic Acid Binding Immunoglobulin-like Lectins - immunology | HIV Infections - immunology | Pneumococcal Infections - immunology | HIV Infections - pathology | Neoplasms - genetics | Sialic Acid Binding Immunoglobulin-like Lectins - chemistry | Reactive Oxygen Species - immunology | Pneumococcal Infections - genetics | Polysaccharides - chemistry | Hypersensitivity - genetics | Schistosomiasis - immunology | Signal Transduction | Gene Expression Regulation - immunology | HIV Infections - genetics | Pneumococcal Infections - pathology | Inflammation - immunology | Polysaccharides - immunology | Immunity, Innate | Sialic Acid Binding Immunoglobulin-like Lectins - genetics | Animals | Hypersensitivity - pathology | Neoplasms - immunology | Inflammation - genetics | Protein Binding | Schistosomiasis - genetics | Neoplasms - pathology | Schistosomiasis - pathology | Proteins | Polysaccharides | Immune response | Lipids | Chemical properties | Organic acids | Protein binding | Enzymes | Immunology | Disease | Rodents | Ligands | Kinases | Immune system | Apoptosis | Endothelium
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2018, Volume 9, p. 2761
LC3-associated phagocytosis (LAP) is an emerging non-canonical autophagy process that bridges signaling from pattern-recognition receptors (PRRs) to autophagic... 
LC3-associated phagocytosis | non-canonical autophagy | NLRX1 | cytokine response | Histoplasma capsulatum | macrophage | innate anti-fungal immunity | RECRUITMENT | PROTEIN | DISTINCT ROLES | AUTOPHAGY | IMMUNOLOGY | PHAGOSOMES | INFLAMMATION | INFECTION | NF-KAPPA-B | NOD-LIKE RECEPTOR | CELL | Phagosomes - microbiology | Reactive Oxygen Species - metabolism | Microtubule-Associated Proteins - metabolism | Lectins, C-Type - immunology | NADPH Oxidases - metabolism | NADPH Oxidases - immunology | Transcription Factor AP-1 - immunology | Autophagy - physiology | Histoplasmosis - microbiology | Transcription Factor AP-1 - metabolism | Histoplasmosis - immunology | Autophagy - immunology | Lectins, C-Type - metabolism | Phagosomes - immunology | Autophagy-Related Protein 12 - immunology | Mitochondrial Proteins - metabolism | Reactive Oxygen Species - immunology | Mitogen-Activated Protein Kinases - immunology | Autophagy-Related Protein 5 - immunology | Macrophages - immunology | Macrophages - microbiology | Cytokines - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Phagosomes - metabolism | Phagocytosis - immunology | Phagocytosis - physiology | Autophagy-Related Protein 12 - metabolism | Histoplasma - immunology | Microtubule-Associated Proteins - immunology | Histoplasmosis - metabolism | Macrophages - metabolism | Animals | Autophagy-Related Protein 5 - metabolism | Mice | Mitochondrial Proteins - immunology | Mitogen-Activated Protein Kinases - metabolism | Reactive oxygen species | Cytokines | Analysis | Genetic aspects | Research | Macrophages | Phagocytosis
Journal Article
PLoS pathogens, ISSN 1553-7374, 2009, Volume 5, Issue 10, pp. e1000639 - e1000639
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 3, p. e0121776
Objective The protein Hwp1, expressed on the pathogenic phase of Candida albicans, presents sequence analogy with the gluten protein gliadin and is also a substrate for transglutaminase... 
ANTIBODIES | RESPONSES | COMMENSAL | PEPTIDES | DENDRITIC CELLS | TRANSGLUTAMINASE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | COLONIZATION | INVASIVE CANDIDIASIS | EPITOPES | Humans | Middle Aged | Fluorescence | Immunoblotting | Male | Candidiasis - microbiology | Young Adult | Candidiasis - blood | Celiac Disease - microbiology | Antibodies, Fungal - isolation & purification | Fungal Proteins - immunology | Immunity, Humoral | Celiac Disease - immunology | Celiac Disease - blood | Celiac Disease - complications | Adult | Candida albicans - physiology | Female | Candidiasis - immunology | Enzyme-Linked Immunosorbent Assay | Gliadin - immunology | Electrophoresis, Polyacrylamide Gel | Peptides - immunology | Biomarkers - blood | Antibodies, Fungal - immunology | Cross Reactions - immunology | Candidiasis - complications | Adolescent | Aged | Infection | Celiac disease | Peptides | Analysis | Immunoglobulin G | Immunoglobulin A | Health aspects | Gluten | Cereals | Disease | Antibodies | Homeostasis | Alcohol | Infections | Small intestine | Immunity | Proteins | Analogs | Gliadin | Immunity (humoral) | Nosocomial infections | microchips | Antigens | Immunoglobulins | Dendritic cells | Cross-reactivity | Patients | Substrates | Hypotheses | Reactivity | Autoimmune diseases | Candidiasis/microbiology | Celiac Disease/complications | Antibodies, Fungal/immunology | Gliadin/immunology | Celiac Disease/immunology | Antibodies, Fungal/isolation & purification | Life Sciences | Celiac Disease/microbiology | Biomarkers/blood | Candidiasis/complications | Candida albicans/physiology | Candidiasis/immunology | Mycology | Cross Reactions/immunology | Microbiology and Parasitology | Celiac Disease/blood | Fungal Proteins/immunology | Candidiasis/blood | Peptides/immunology
Journal Article
Journal Article