Chemical Communications, ISSN 1359-7345, 2019, Volume 55, Issue 49, pp. 7009 - 7012
Expanding the chemical space of quinolones led to a tandem quinolone-alkyne-cyclisation reaction allowing chemoselective control of the synthesis of tricyclic...
RESPIRATORY-CHAIN | PLASMODIUM-FALCIPARUM | GROWTH | TOXOPLASMA-GONDII | ANTIMALARIALS | INHIBITORS | FUROQUINOLINE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
RESPIRATORY-CHAIN | PLASMODIUM-FALCIPARUM | GROWTH | TOXOPLASMA-GONDII | ANTIMALARIALS | INHIBITORS | FUROQUINOLINE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
Journal Article
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, ISSN 1972-2680, 03/2019, Volume 13, Issue 3, pp. 240 - 244
Introduction: In the classic treatment of Trichomonas vaginalis infection, although metronidazole has been used since the 1960s, there has been an increase in...
INFECTIOUS DISEASES | Haplophyllum myrtifolium | antitrichomonal activity | FUROQUINOLINE | Trichomanas vaginalis | ALKALOIDS
INFECTIOUS DISEASES | Haplophyllum myrtifolium | antitrichomonal activity | FUROQUINOLINE | Trichomanas vaginalis | ALKALOIDS
Journal Article
Natural Product Reports, ISSN 0265-0568, 2008, Volume 25, Issue 1, pp. 166 - 187
This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant,...
KEY BUILDING-BLOCKS | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUROQUINOLINE ALKALOIDS | STEM BARK | CHEMISTRY, ORGANIC | GLABERRIMA ENGL. RUTACEAE | MICROWAVE IRRADIATION | POT TOTAL SYNTHESES | THIOSTREPTON FAMILY | CONCISE SYNTHESIS | STEREOCONTROLLED SYNTHESIS | 2-AMINOBENZYL ALCOHOL | Acridines - chemistry | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Animals | Acridones | Quinolines - chemistry | Molecular Structure | Fungi - chemistry | Quinazolines - chemistry | Alkaloids - chemistry
KEY BUILDING-BLOCKS | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUROQUINOLINE ALKALOIDS | STEM BARK | CHEMISTRY, ORGANIC | GLABERRIMA ENGL. RUTACEAE | MICROWAVE IRRADIATION | POT TOTAL SYNTHESES | THIOSTREPTON FAMILY | CONCISE SYNTHESIS | STEREOCONTROLLED SYNTHESIS | 2-AMINOBENZYL ALCOHOL | Acridines - chemistry | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Animals | Acridones | Quinolines - chemistry | Molecular Structure | Fungi - chemistry | Quinazolines - chemistry | Alkaloids - chemistry
Journal Article
Asian Journal of Chemistry, ISSN 0970-7077, 07/2015, Volume 27, Issue 7, pp. 2468 - 2472
Journal Article
Organic Letters, ISSN 1523-7060, 08/2011, Volume 13, Issue 15, pp. 4136 - 4139
A novel, efficient route to biologically and pharmaceutically important o-(dimethylamino)aryl ketones and acridones has been developed starting from readily...
ARYLATION | CHEMISTRY, ORGANIC | INHIBITORS | DERIVATIVES | FUROQUINOLINE | BENZYNE | ALKALOIDS
ARYLATION | CHEMISTRY, ORGANIC | INHIBITORS | DERIVATIVES | FUROQUINOLINE | BENZYNE | ALKALOIDS
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 52, pp. 46073 - 46080
A simple route for preparation of 4-substituted thieno/furo[2,3-c]quinoline compounds is reported in this paper. These compounds were synthesized by using...
DESIGN | FACILE SYNTHESIS | ACID | PHENANTHRIDINE | RECEPTOR 8 | DERIVATIVES | THIENOQUINOLINES | FUROQUINOLINE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
DESIGN | FACILE SYNTHESIS | ACID | PHENANTHRIDINE | RECEPTOR 8 | DERIVATIVES | THIENOQUINOLINES | FUROQUINOLINE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
Journal Article
Natural Product Reports, ISSN 0265-0568, 2007, Volume 24, Issue 1, pp. 223 - 246
This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant,...
HERB EVODIA-RUTAECARPA | CHEMISTRY, MEDICINAL | ONE-POT SYNTHESIS | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUROQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | ABSOLUTE STEREOCHEMISTRY | POSTHARVEST TREATMENTS | CYANOBACTERIUM ANABAENA-CYLINDRICA | ISATIS-TINCTORIA LEAVES | LUOTONIN-A | METABOLITE PRODUCTION | Acridines - chemistry | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Animals | Acridones | Quinolines - chemistry | Molecular Structure | Fungi - chemistry | Quinazolines - chemistry | Alkaloids - chemistry
HERB EVODIA-RUTAECARPA | CHEMISTRY, MEDICINAL | ONE-POT SYNTHESIS | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUROQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | ABSOLUTE STEREOCHEMISTRY | POSTHARVEST TREATMENTS | CYANOBACTERIUM ANABAENA-CYLINDRICA | ISATIS-TINCTORIA LEAVES | LUOTONIN-A | METABOLITE PRODUCTION | Acridines - chemistry | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Animals | Acridones | Quinolines - chemistry | Molecular Structure | Fungi - chemistry | Quinazolines - chemistry | Alkaloids - chemistry
Journal Article
Organic Letters, ISSN 1523-7060, 11/2017, Volume 19, Issue 22, pp. 6124 - 6127
An efficient approach for the synthesis of pyranoquinolines through the indium-catalyzed activation of alkynes is reported. Intramolecular hydroamidation of...
ELECTROPHILIC CYCLIZATION | MULTICOMPONENT REACTIONS | GOLD CATALYSIS | HETEROCYCLES | LEWIS-ACID | ACETYLENIC ALDEHYDES | SILVER | FUROQUINOLINES | QUINOLINES | CHEMISTRY, ORGANIC | ACCESS
ELECTROPHILIC CYCLIZATION | MULTICOMPONENT REACTIONS | GOLD CATALYSIS | HETEROCYCLES | LEWIS-ACID | ACETYLENIC ALDEHYDES | SILVER | FUROQUINOLINES | QUINOLINES | CHEMISTRY, ORGANIC | ACCESS
Journal Article
Phytochemistry, ISSN 0031-9422, 2008, Volume 69, Issue 6, pp. 1384 - 1388
The limonoid, methyl uguenesonate, , the azole, uguenenazole, , and the amide, uguenenonamide, together with the known furoquinoline alkaloids flindersiamine...
Maculosidine | Azole | Antimalarial activity | Uguenenonamide | Uguenenzole | Rutaceae | Amide | Furoquinoline alkaloid | Vepris uguenensis | Limonoid | Methyl uguenenoate | Flindersiamine | furoquinoline alkaloid | maculosidine | LOUISII | limonoid | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESSENTIAL OIL | uguenenonamide | antimalarial activity | TRADITIONAL MEDICINE | FUROQUINOLINE | PLANT SCIENCES | methyl uguenenoate | amide | PLASMODIUM-FALCIPARUM | flindersiamine | A-D | PLANTS | HETEROPHYLLA | uguenenzole | azole | ALKALOIDS
Maculosidine | Azole | Antimalarial activity | Uguenenonamide | Uguenenzole | Rutaceae | Amide | Furoquinoline alkaloid | Vepris uguenensis | Limonoid | Methyl uguenenoate | Flindersiamine | furoquinoline alkaloid | maculosidine | LOUISII | limonoid | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESSENTIAL OIL | uguenenonamide | antimalarial activity | TRADITIONAL MEDICINE | FUROQUINOLINE | PLANT SCIENCES | methyl uguenenoate | amide | PLASMODIUM-FALCIPARUM | flindersiamine | A-D | PLANTS | HETEROPHYLLA | uguenenzole | azole | ALKALOIDS
Journal Article
Tetrahedron, ISSN 0040-4020, 11/2012, Volume 68, Issue 44, pp. 9035 - 9044
A facile, efficient, and general synthetic method for a wide range of medicinally useful 2-carboxylate derivatives of acridinols, quinolinols, and...
Regioselective | Silver-catalyzed | Diketoacid | Electrophilic cyclization | Enolates | VERSATILE ACCESS | TOPOISOMERASE-II | TANDEM SYNTHESIS | CHEMISTRY, ORGANIC | FUROQUINOLINE | IN-VITRO | HETEROCYCLES | INHIBITORS | EFFICIENT | ANTIMICROBIAL ACTIVITY | CYCLIZATION
Regioselective | Silver-catalyzed | Diketoacid | Electrophilic cyclization | Enolates | VERSATILE ACCESS | TOPOISOMERASE-II | TANDEM SYNTHESIS | CHEMISTRY, ORGANIC | FUROQUINOLINE | IN-VITRO | HETEROCYCLES | INHIBITORS | EFFICIENT | ANTIMICROBIAL ACTIVITY | CYCLIZATION
Journal Article
Medicinal Research Reviews, ISSN 0198-6325, 05/2018, Volume 38, Issue 3, pp. 775 - 828
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic compounds, have attracted tremendous attention from researchers worldwide...
quinoline alkaloids | camptothecin | quinazoline alkaloids | quinine | bioactivities | CHEMISTRY, MEDICINAL | EVODIA-RUTAECARPA | INHIBITORY-ACTIVITY | ANTIPLATELET AGGREGATION CONSTITUENTS | FUROQUINOLINE ALKALOIDS | PLANT ANTITUMOR AGENTS | HELICOBACTER-PYLORI ACTIVITY | LUOTONIN-A | CYTOTOXIC CONSTITUENTS | PHARMACOLOGY & PHARMACY | 2-SUBSTITUTED QUINOLINES | FREE-RADICAL SCAVENGERS | Immunologic Factors - chemistry | Alkaloids - pharmacology | Animals | Protective Agents - pharmacology | Humans | Quinolines - chemistry | Protective Agents - chemistry | Quinazolines - pharmacology | Quinazolines - chemistry | Alkaloids - chemistry | Immunologic Factors - pharmacology | Quinolines - pharmacology | Quinoline | Antiviral agents | Alkaloids
quinoline alkaloids | camptothecin | quinazoline alkaloids | quinine | bioactivities | CHEMISTRY, MEDICINAL | EVODIA-RUTAECARPA | INHIBITORY-ACTIVITY | ANTIPLATELET AGGREGATION CONSTITUENTS | FUROQUINOLINE ALKALOIDS | PLANT ANTITUMOR AGENTS | HELICOBACTER-PYLORI ACTIVITY | LUOTONIN-A | CYTOTOXIC CONSTITUENTS | PHARMACOLOGY & PHARMACY | 2-SUBSTITUTED QUINOLINES | FREE-RADICAL SCAVENGERS | Immunologic Factors - chemistry | Alkaloids - pharmacology | Animals | Protective Agents - pharmacology | Humans | Quinolines - chemistry | Protective Agents - chemistry | Quinazolines - pharmacology | Quinazolines - chemistry | Alkaloids - chemistry | Immunologic Factors - pharmacology | Quinolines - pharmacology | Quinoline | Antiviral agents | Alkaloids
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2014, Volume 70, Issue 34, pp. 5310 - 5320
Two new synthetic methodologies for 2,3-diarylacridin-9(10 )-ones were developed. The first one involves the Heck reaction of ( )-3-iodo-2-styrylquinolin-4(1...
Heck reaction | Electrocyclization reactions | Acridin-9(10H)-ones | Furoquinolines | N-Methylation | DESIGN | FUROQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | ANTITUMOR | HERPES-SIMPLEX-VIRUS | FLUORESCENCE | CIS-TRANS ISOMERIZATION | PART 2 | INHIBITORS | ANTILEISHMANIAL ACTIVITY | ACRIDONE DERIVATIVES | Substitution reactions | Quinoline | Analysis | Methods | Tetrahedrons | Oxidation | Derivatives | Nuclear magnetic resonance | Styrenes
Heck reaction | Electrocyclization reactions | Acridin-9(10H)-ones | Furoquinolines | N-Methylation | DESIGN | FUROQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | ANTITUMOR | HERPES-SIMPLEX-VIRUS | FLUORESCENCE | CIS-TRANS ISOMERIZATION | PART 2 | INHIBITORS | ANTILEISHMANIAL ACTIVITY | ACRIDONE DERIVATIVES | Substitution reactions | Quinoline | Analysis | Methods | Tetrahedrons | Oxidation | Derivatives | Nuclear magnetic resonance | Styrenes
Journal Article