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by Guo, G and Kang, Q and Zhu, X and Chen, Q and Wang, X and Chen, Y and Ouyang, J and Zhang, L and Tan, H and Chen, R and Huang, S and Chen, J.-L
Oncogene, ISSN 0950-9232, 04/2015, Volume 34, Issue 14, pp. 1768 - 1779
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 12/2008, Volume 68, Issue 23, pp. 9809 - 9816
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 360, Issue 2, pp. 245 - 256
Highlights • MiR-424 expression is low in CML cell lines and patient samples at time of diagnosis. • Using bioinformatics we revealed a conserved miR-424... 
Hematology, Oncology and Palliative Medicine | BCR–ABL | Imatinib | miR-424 | CML | Apoptosis | MiR-424 | BCR-ABL | EXPRESSION PROFILES | MIR-16 FAMILY | CHRONIC MYELOID-LEUKEMIA | TYROSINE KINASE INHIBITORS | SMALL INTERFERING RNA | LYMPHOCYTIC-LEUKEMIA | ONCOLOGY | ENDOTHELIAL-CELLS | GENE-EXPRESSION | CYCLE PROGRESSION | MICRORNA EXPRESSION | Apoptosis - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Apoptosis - genetics | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy | Fusion Proteins, bcr-abl - biosynthesis | Transfection | Base Sequence | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Cell Growth Processes - genetics | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Cell Growth Processes - drug effects | MicroRNAs - administration & dosage | Down-Regulation | MicroRNAs - biosynthesis | Combined Modality Therapy | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Fusion Proteins, bcr-abl - genetics | Fusion Proteins, bcr-abl - antagonists & inhibitors | K562 Cells | HL-60 Cells | MicroRNAs - genetics | HeLa Cells | Fusion Proteins, bcr-abl - metabolism | Antimitotic agents | Antineoplastic agents | Cell growth | Kinases | Leukemia | Cell cycle
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 20, Issue 3, pp. 357 - 369
We show constitutive activation of Rho kinase (ROCK) in cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL, which is dependent on PI3K and Rho GTPase.... 
CHRONIC MYELOGENOUS LEUKEMIA | INTERNAL TANDEM DUPLICATION | WILD-TYPE | SMOOTH-MUSCLE | ONCOLOGY | TYROSINE KINASE | CONSTITUTIVE ACTIVATION | ROCK-I | C-KIT | ACUTE MYELOID-LEUKEMIA | GASTROINTESTINAL STROMAL TUMORS | CELL BIOLOGY | fms-Like Tyrosine Kinase 3 - biosynthesis | Phosphorylation | Cell Proliferation | Leukemia - pathology | Myosin Light Chains - genetics | Protein-Tyrosine Kinases - metabolism | Humans | Leukemia, Myeloid, Acute - metabolism | Actins - metabolism | Apoptosis - genetics | Leukemia - metabolism | Myeloproliferative Disorders - pathology | Stem Cell Factor - genetics | Fusion Proteins, bcr-abl - biosynthesis | rho-Associated Kinases - antagonists & inhibitors | Myosin Light Chains - biosynthesis | fms-Like Tyrosine Kinase 3 - genetics | Protein-Tyrosine Kinases - genetics | RNA Interference | rho-Associated Kinases - metabolism | Myeloproliferative Disorders - metabolism | Stem Cell Factor - biosynthesis | Phosphatidylinositol 3-Kinases - biosynthesis | Protein-Tyrosine Kinases - biosynthesis | Stem Cell Factor - metabolism | Cell Survival | Leukemia, Myeloid, Acute - pathology | Mice, Inbred C57BL | rho-Associated Kinases - genetics | Signal Transduction - genetics | Mice, Inbred C3H | fms-Like Tyrosine Kinase 3 - metabolism | Leukemia, Myeloid, Acute - mortality | Fusion Proteins, bcr-abl - genetics | Animals | Cell Transformation, Neoplastic | Cell Line, Tumor | Mice | Myosin Light Chains - metabolism | RNA, Small Interfering | rho GTP-Binding Proteins - biosynthesis | Fusion Proteins, bcr-abl - metabolism | Myeloproliferative Disorders - mortality | Leukemia - mortality | Actin | Immunotherapy | Oncology, Experimental | Leukemia | Myosin | Polymerization | Research | Muscle proteins | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 10/2015, Volume 75, Issue 19, pp. 4053 - 4062
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 10/2005, Volume 65, Issue 19, pp. 8912 - 8919
Journal Article
Journal Article
Journal Article
Journal Article
Journal Article