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Leukemia, ISSN 0887-6924, 2019, Volume 33, Issue 7, pp. 1583 - 1597
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Leukemia, Large Granular Lymphocytic - drug therapy | Cell Proliferation | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | STAT5 Transcription Factor - genetics | STAT5 Transcription Factor - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Tumor Suppressor Proteins - genetics | Antineoplastic Agents - pharmacology | Leukemia, Large Granular Lymphocytic - pathology | Tumor Suppressor Proteins - metabolism | Interferons - pharmacology | Survival Rate | Mice, SCID | Cell Transformation, Neoplastic - metabolism | Mice, Knockout | Xenograft Model Antitumor Assays | Fusion Proteins, bcr-abl - genetics | Animals | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Leukemia, Large Granular Lymphocytic - metabolism | Mice, Inbred NOD | Mice | Cell Transformation, Neoplastic - drug effects | Mutation | Cell Transformation, Neoplastic - pathology | Fusion Proteins, bcr-abl - metabolism | RNA sequencing | Usage | Gene mutations | Leukemia | Development and progression | Genetic aspects | Cellular signal transduction | Research | BCR protein | Biotechnology | Transformation | Deregulation | Transcription factors | Profiling | Transcription | Abl gene | BCR gene | Kinases | Gene sequencing | α-Interferon | Signal transduction | Janus kinase | Transducers | Cell survival | Colonies | Inhibition (psychology) | Stat5 protein | Ribonucleic acid--RNA | Disease control | Survival | Hemopoiesis | Lymphocytes B | γ-Interferon | Leukemogenesis | Interferon | Tumors | Index Medicus | Cell signalling | Acute lymphocytic leukaemia
Journal Article
Blood, ISSN 0006-4971, 12/2007, Volume 110, Issue 12, pp. 4055 - 4063
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Chemotherapy | Pharmacology. Drug treatments | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Antineoplastic agents | Protein-Tyrosine Kinases - metabolism | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Piperazines - chemistry | Thiazoles - therapeutic use | Neoplasm Proteins - metabolism | Pyrimidines - chemistry | Dose-Response Relationship, Drug | Protein Kinase Inhibitors - chemistry | Fusion Proteins, bcr-abl | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Dasatinib | Quinone Reductases - metabolism | Piperazines - therapeutic use | Discoidin Domain Receptor 1 | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Imatinib Mesylate | Piperazines - pharmacology | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Quinone Reductases - antagonists & inhibitors | K562 Cells | Proteomics | Thiazoles - chemistry | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Benzamides | Drug Screening Assays, Antitumor | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Nature (London), ISSN 0028-0836, 01/2010, Volume 463, Issue 7280, pp. 501 - 506
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Male | Transplantation, Heterologous | Piperazines - chemistry | Pyrimidines - chemistry | Pyrimidines - metabolism | Antineoplastic Agents - metabolism | Mass Spectrometry | Bone Marrow Transplantation | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Binding Sites | Disease Models, Animal | Fusion Proteins, bcr-abl - chemistry | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - enzymology | Protein Structure, Tertiary | Crystallization | Antineoplastic Combined Chemotherapy Protocols | Models, Molecular | Pyrimidines - pharmacology | Antineoplastic Agents - chemistry | Mutation - genetics | Imatinib Mesylate | Piperazines - pharmacology | Fusion Proteins, bcr-abl - genetics | Animals | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Mice | Benzamides | Fusion Proteins, bcr-abl - metabolism | Drug Resistance, Neoplasm - drug effects | Nilotinib | Dasatinib | Drug resistance in microorganisms | Usage | Nuclear magnetic resonance spectroscopy | Research | Chronic myeloid leukemia | X-ray crystallography | Chromosome abnormalities | Gene mutations | Analysis | Genetic aspects | Diagnosis | Binding proteins | Drug therapy | Health aspects | Proteins | Studies | Competition | Enzymes | E coli | Kinases | Drug resistance | Crystal structure | Index Medicus
Journal Article