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Journal of Biological Chemistry, ISSN 0021-9258, 2016, Volume 291, Issue 18, pp. 9700 - 9711
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e109882 - e109882
Human heteromeric amino acid transporters (HATs) are membrane protein complexes that facilitate the transport of specific amino acids across cell membranes.... 
CYSTINE | SYSTEM | LIGHT SUBUNIT | MECHANISM | RBAT | MULTIDISCIPLINARY SCIENCES | PICHIA-PASTORIS | MUTATIONS | MEMBRANE-PROTEINS | ANTIPORTER | FAMILY | Detergents - pharmacology | Amino Acid Transport System y+ - chemistry | Amino Acid Transport Systems - chemistry | Humans | Amino Acid Transport System y+ - isolation & purification | Amino Acids - chemistry | Fusion Regulatory Protein 1, Light Chains - isolation & purification | Amino Acid Transport Systems - metabolism | Fusion Regulatory Protein 1, Heavy Chain - chemistry | Fusion Regulatory Protein 1, Light Chains - chemistry | Pichia | Recombinant Proteins - isolation & purification | Amino Acids - metabolism | Multiprotein Complexes - chemistry | Amino Acid Transport System y+ - metabolism | Fusion Regulatory Protein 1, Light Chains - metabolism | Maltose - analogs & derivatives | Maltose - pharmacology | Recombinant Proteins - drug effects | Protein Stability - drug effects | Fusion Regulatory Protein 1, Heavy Chain - isolation & purification | Amino Acid Transport Systems - isolation & purification | Fusion Regulatory Protein 1, Heavy Chain - metabolism | Multiprotein Complexes - isolation & purification | Amino acids | Detergents, Synthetic | Membranes | Yeast | Stabilization | Trafficking | Biochemistry | Pichia pastoris | Polyamines | Experiments | Proteins | Life sciences | Stains | Recombinant | Crystallization | Outerwear | Glycoproteins | Cell membranes | Maltose | Cell membranes (biology) | Electron microscopy | Detergents | Substrates | Membrane proteins | Medicine | Transmission electron microscopy | Mutagenesis | Microscopy | Transport | Transporter | Cancer | Index Medicus | Aminoàcids | Biological transport | Transport biològic
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 09/2013, Volume 59, pp. 137 - 144
We investigated the underlying mechanisms of -leucine and -isoleucine mediated promotion of bladder carcinogenesis using an initiation-promotion model. Rats... 
Amino acid transporters | l-isoleucine | l-leucine | Tumorigenesis-associated genes | L-leucine | L-isoleucine | SYSTEM-L | CELLS | LYSINURIC PROTEIN INTOLERANCE | FOOD SCIENCE & TECHNOLOGY | IDENTIFICATION | P53 | CHAIN | LAT1 | INHIBITION | IN-VIVO | TOXICOLOGY | PROSTATE-CANCER PROGRESSION | Amino Acids, Branched-Chain - adverse effects | Urothelium - metabolism | Large Neutral Amino Acid-Transporter 1 - metabolism | Amino Acids, Branched-Chain - metabolism | Carcinogenesis - chemically induced | Hyperplasia | Rats, Inbred F344 | Gene Expression Regulation, Neoplastic | Amino Acid Transport System y+ - genetics | Male | Urinary Bladder - pathology | Leucine - adverse effects | Neoplasm Proteins - metabolism | Carcinogenesis - metabolism | Urinary Bladder Neoplasms - chemically induced | Urothelium - pathology | Amino Acid Transport System y+ - metabolism | Fusion Regulatory Protein 1, Light Chains - metabolism | Isoleucine - adverse effects | Fusion Regulatory Protein 1, Heavy Chain - biosynthesis | Fusion Regulatory Protein 1, Heavy Chain - genetics | Urinary Bladder Neoplasms - pathology | Dietary Supplements - adverse effects | Neoplasm Proteins - genetics | Urinary Bladder Neoplasms - metabolism | Leucine - metabolism | Urinary Bladder - metabolism | Neoplasm Proteins - biosynthesis | Rats | Amino Acid Transport Systems, Neutral - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Amino Acid Transport Systems - biosynthesis | Fusion Regulatory Protein 1, Light Chains - genetics | Random Allocation | Tumor Burden | Amino Acid Transport Systems - metabolism | Fusion Regulatory Protein 1, Light Chains - biosynthesis | Amino Acid Transport Systems, Neutral - genetics | Isoleucine - metabolism | Amino Acid Transport System y+ - biosynthesis | Animals | Large Neutral Amino Acid-Transporter 1 - biosynthesis | Amino Acid Transport Systems - genetics | Amino Acid Transport Systems, Neutral - biosynthesis | Urinary Bladder - drug effects | Urothelium - drug effects | Fusion Regulatory Protein 1, Heavy Chain - metabolism | Amino acids | Genes | Tumors | Index Medicus
Journal Article
Amino Acids, ISSN 0939-4451, 4/2014, Volume 46, Issue 4, pp. 883 - 892
Journal Article
Endocrinology, ISSN 0013-7227, 07/2013, Volume 154, Issue 7, pp. 2533 - 2541
Patients with the monocarboxylate transporter 8 (MCT8) deficiency syndrome present with a severe psychomotor retardation and abnormal serum thyroid hormone... 
HORMONE TRANSPORTERS | CONGENITAL HYPERTHYROIDISM | MOUSE CEREBRAL-CORTEX | DEPRIVATION | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | MONOCARBOXYLATE TRANSPORTER-8 | MUTATIONS | PAROXYSMAL KINESIGENIC DYSKINESIA | DEIODINASES | LINKED PSYCHOMOTOR RETARDATION | Hypothyroidism - chemically induced | Hypothyroidism - metabolism | Organic Anion Transporters, Sodium-Independent - genetics | Thyroxine - blood | Amino Acid Transport System y+ - genetics | Male | Cerebral Cortex - metabolism | Organic Anion Transporters - metabolism | Membrane Transport Proteins - deficiency | Organic Anion Transporters - genetics | Amino Acid Transport System y+ - metabolism | Fusion Regulatory Protein 1, Light Chains - metabolism | Liver - drug effects | Membrane Transport Proteins - genetics | Organic Anion Transporters, Sodium-Independent - metabolism | Thyroid Hormones - blood | Iodide Peroxidase - metabolism | Female | Membrane Transport Proteins - metabolism | Cerebral Cortex - drug effects | Thyroid Gland - drug effects | Thyrotropin - blood | Organic Cation Transport Proteins - metabolism | Liver - metabolism | Fusion Regulatory Protein 1, Light Chains - genetics | Mice, Knockout | Pregnancy | Triiodothyronine - blood | Animals | Mice | Organic Cation Transport Proteins - genetics | Thyroid Gland - metabolism | Thyroxine - pharmacology | Index Medicus | Abridged Index Medicus | Thyroid-TRH-TSH
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 03/2017, Volume 443, Issue C, pp. 163 - 174
Journal Article
Clinical Science, ISSN 0143-5221, 2016, Volume 130, Issue 7, pp. 499 - 512
Journal Article
Glia, ISSN 0894-1491, 03/2011, Volume 59, Issue 3, pp. 463 - 471
Cellular thyroid hormone uptake and efflux are mediated by transmembrane transport proteins. One of these, monocarboxylate transporter 8 (MCT8) is mutated in... 
neuron | development | blood–brain‐barrier | astrocyte | microglia | Blood-brain-barrier | Development | Neuron | Astrocyte | Microglia | HERNDON-DUDLEY-SYNDROME | PRIMARY CULTURE | RAT | IODOTHYRONINE DEIODINASE | MONOCARBOXYLATE TRANSPORTER-8 | NEUROSCIENCES | CEREBRAL-CORTEX | MCT8 GENE | PSYCHOMOTOR RETARDATION | BLOOD-BRAIN | blood brain-barrier | CEREBROSPINAL-FLUID BARRIERS | Coculture Techniques | Humans | Neurons - cytology | Protein Transport - physiology | Brain - growth & development | Brain - metabolism | Membrane Transport Proteins - deficiency | Amino Acid Transport System y+ - metabolism | Fusion Regulatory Protein 1, Light Chains - metabolism | Triiodothyronine - metabolism | Membrane Transport Proteins - genetics | HEK293 Cells | Neurons - metabolism | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Astrocytes - cytology | Cell Line | Brain - cytology | Mice, Inbred C57BL | Cells, Cultured | Fusion Regulatory Protein 1, Light Chains - biosynthesis | Mice, Knockout | Amino Acid Transport System y+ - biosynthesis | Animals | Thyroxine - metabolism | Mice | Astrocytes - metabolism | Brain | Cell culture | Astrocytes | Immunocytochemistry | Neurons | Amino acids | mRNA | Mental retardation | Endothelial cells | Western blotting | Myelination | Thyroxine | Microvasculature | Thyroid hormones | Index Medicus
Journal Article
Journal Article