X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (22244) 22244
Publication (2968) 2968
Newsletter (511) 511
Book Chapter (417) 417
Book Review (350) 350
Book / eBook (242) 242
Conference Proceeding (115) 115
Reference (56) 56
Dissertation (32) 32
Newspaper Article (6) 6
Web Resource (4) 4
Magazine Article (3) 3
Data Set (2) 2
Government Document (1) 1
Presentation (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (10621) 10621
humans (8897) 8897
index medicus (8881) 8881
biochemistry & molecular biology (4683) 4683
g proteins (4053) 4053
proteins (3716) 3716
signal transduction (3271) 3271
mice (3268) 3268
cell biology (2897) 2897
rats (2544) 2544
pharmacology & pharmacy (2535) 2535
male (2479) 2479
neurosciences (2405) 2405
receptors, g-protein-coupled - metabolism (2314) 2314
analysis (2085) 2085
immunoglobulin g (2028) 2028
female (2017) 2017
article (1976) 1976
protein binding (1965) 1965
activation (1903) 1903
ligands (1885) 1885
research (1846) 1846
amino acid sequence (1831) 1831
molecular sequence data (1801) 1801
physiological aspects (1723) 1723
biophysics (1621) 1621
expression (1541) 1541
receptors (1532) 1532
g-protein (1506) 1506
gtp-binding proteins - metabolism (1465) 1465
binding (1464) 1464
membrane proteins (1429) 1429
multidisciplinary sciences (1423) 1423
g protein-coupled receptors (1392) 1392
cell line (1318) 1318
immunology (1294) 1294
cells (1261) 1261
g protein (1221) 1221
models, molecular (1194) 1194
phosphorylation (1179) 1179
physiology (1146) 1146
research article (1124) 1124
g-proteins (1087) 1087
binding sites (1076) 1076
cells, cultured (1069) 1069
g protein-coupled receptor (1062) 1062
signal transduction - physiology (1036) 1036
receptors, g-protein-coupled - genetics (1029) 1029
kinetics (1014) 1014
receptor (998) 998
antibodies (979) 979
medicine (976) 976
biology (972) 972
peptides (962) 962
protein-coupled receptors (960) 960
crystal-structure (955) 955
gene expression (952) 952
biochemistry (945) 945
protein (901) 901
science (898) 898
immunoglobulin g - immunology (878) 878
protein conformation (871) 871
chemistry, analytical (847) 847
calcium - metabolism (846) 846
endocrinology & metabolism (829) 829
life sciences (829) 829
biochemical research methods (827) 827
identification (823) 823
mutation (821) 821
signal transduction - drug effects (815) 815
dose-response relationship, drug (787) 787
receptors, g-protein-coupled - chemistry (773) 773
neurons (771) 771
pharmacology (735) 735
rats, sprague-dawley (734) 734
kinases (728) 728
pertussis toxin (727) 727
gpcr (719) 719
biotechnology & applied microbiology (717) 717
cyclic amp - metabolism (712) 712
cell membrane - metabolism (704) 704
cho cells (697) 697
cancer (685) 685
cricetinae (680) 680
models, biological (679) 679
calcium (676) 676
enzyme-linked immunosorbent assay (670) 670
molecular biology (669) 669
brain (661) 661
structure-activity relationship (660) 660
protein-coupled receptor (646) 646
rodents (646) 646
transfection (646) 646
hek293 cells (641) 641
signal-transduction (621) 621
antigens (608) 608
in-vivo (590) 590
signaling (586) 586
protein structure, tertiary (585) 585
rabbits (582) 582
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (107) 107
UofT at Mississauga - Stacks (46) 46
Robarts - Stacks (43) 43
UofT at Scarborough - Stacks (26) 26
Collection Dvlpm't (Acquisitions) - Vendor file (24) 24
UTL at Downsview - May be requested (22) 22
Collection Dvlpm't (Acquisitions) - Closed Orders (20) 20
Earth Sciences (Noranda) - Stacks (15) 15
Online Resources - Online (15) 15
St. Michael's College (John M. Kelly) - 2nd Floor (11) 11
Victoria University E.J. Pratt - Stacks (8) 8
Engineering & Comp. Sci. - Stacks (6) 6
Trinity College (John W Graham) - Stacks (6) 6
Royal Ontario Museum - Stacks (5) 5
Chemistry (A D Allen) - Stacks (3) 3
St. Michael's Hospital - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Baycrest Hospital - Stacks (2) 2
New College (Ivey) - Stacks (2) 2
OISE - Stacks (2) 2
Physics - Stacks (2) 2
Thomas Fisher Rare Book - Rare Book (2) 2
UofT at Scarborough - May be requested in 6-10 wks (2) 2
Victoria University E.J. Pratt - Reference (2) 2
Aerospace - Stacks (1) 1
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Earth Sciences (Noranda) - Circulation Desk (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Faculty of Information - Stacks (1) 1
Gerstein Science - Circulation Desk (1) 1
Gerstein Science - Reference (1) 1
Innis College - Stacks (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Law (Bora Laskin) - Stacks (1) 1
Map & Data - Map Collection (1) 1
Massey College (Robertson Davies) - Rare Book (1) 1
Physics - Storage (1) 1
Robarts - Course Reserves (1) 1
Robarts - Storage (1) 1
Scarborough Hospital - General (1) 1
St Josephs Health Centre - Stacks (1) 1
St. Michael's College (John M. Kelly) - 3rd Floor (1) 1
St. Michael's Hospital - Circulation Desk (1) 1
Toronto East General Hospital - Stacks (1) 1
Trinity College (John W Graham) - Storage (1) 1
University College (Laidlaw) - Stacks (1) 1
UofT Schools - Stacks (1) 1
Victoria University E.J. Pratt - Canadiana (1) 1
Victoria University E.J. Pratt - Northrop Frye (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (23189) 23189
Spanish (19) 19
German (15) 15
Japanese (14) 14
French (13) 13
Russian (8) 8
Chinese (6) 6
Korean (3) 3
Portuguese (3) 3
Arabic (1) 1
Bulgarian (1) 1
Italian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


CELL, ISSN 0092-8674, 06/2019, Volume 177, Issue 7, pp. 1933 - 1933
Heterotrimetic G proteins consist of four subfamilies (G(s), G(i/o), G(q/11), and G(12/13)) that mediate signaling via G-protein-coupled receptors (GPCRs),... 
STRUCTURAL COMMUNICATION | DESIGNER RECEPTORS | ACTIVATION | SPECIFICITY | DETERMINANTS | SUBTYPES | BIOCHEMISTRY & MOLECULAR BIOLOGY | P2Y RECEPTOR | BIASED-AGONISM | DISCOVERY | PREDICTION | CELL BIOLOGY | Medicine, Experimental | Medical research | G proteins | Transforming growth factors | Membrane proteins
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 40, pp. 16342 - 16347
Journal Article
BIOCHEMICAL PHARMACOLOGY, ISSN 0006-2952, 05/2018, Volume 151, pp. 201 - 213
A(2B) adenosine receptor (A(2B)AR) activation induces Gs-dependent cyclic AMP accumulation. However, A(2B)AR G protein-coupling to other signaling events, e.g.... 
SIGNALING PATHWAYS | ACTIVATION | G(I) PROTEINS | Calcium | MAST-CELLS | KINASE | MUSCLE-CELL PROLIFERATION | PERTUSSIS TOXIN | SKELETAL-MUSCLE | ERK1/2 | CYCLIC-AMP | A2B adenosine receptor | G(S) | GPCR | PHARMACOLOGY & PHARMACY | Adenosine receptor | G protein
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e67244
Based on the recently described crystal structure of the beta(2) adrenergic receptor - G(s)-protein complex, we report the first molecular-dynamics simulations... 
AMINO-TERMINUS | DOPAMINE-D-2 RECEPTOR | LIGAND-BINDING | ALPHA-SUBUNIT | STRUCTURAL BASIS | BETA-ADRENERGIC-RECEPTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | SYNTHETIC PEPTIDES | FREE-ENERGIES | BETA-ADRENERGIC RECEPTOR | Amino Acid Sequence | Protein Structure, Secondary | Receptors, G-Protein-Coupled - metabolism | Receptors, Dopamine - metabolism | Molecular Sequence Data | Histidine - metabolism | GTP-Binding Protein alpha Subunits, Gi-Go - chemistry | Molecular Dynamics Simulation | Receptors, Adrenergic, beta-2 - metabolism | Receptors, Adrenergic, beta-2 - chemistry | Receptors, Dopamine - chemistry | Multiprotein Complexes - metabolism | Sequence Alignment | Alanine - genetics | Mutagenesis | Models, Biological | Ligands | Structural Homology, Protein | Binding Sites | GTP-Binding Protein alpha Subunits, Gi-Go - metabolism | Dopamine - metabolism | Receptors, G-Protein-Coupled - chemistry | GTP-Binding Proteins - metabolism | Molecular dynamics | Amino acids | Structure | Crystals | Protein binding | Drugs | G protein-coupled receptors | Physical chemistry | Selectivity | Coupling (molecular) | Proteins | Signal transduction | Hydrogen bonds | Physiology | Crystal structure | Binding | Alanine | Dopamine | Computer simulation | Scanning mutagenesis | C-Terminus | Studies | Pharmacy | Computer applications | Determinants | Adrenergic receptors
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 05/2018, Volume 151, pp. 201 - 213
A adenosine receptor (A AR) activation induces Gs-dependent cyclic AMP accumulation. However, A AR G protein-coupling to other signaling events, e.g. ERK1/2... 
GPCR | ERK1/2 | Adenosine receptor | Calcium | A2B adenosine receptor | G protein | adenosine receptor | ERK1 | calcium
Journal Article