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1. Full Text GM1 Ganglioside: Past Studies and Future Potential
by Aureli, Massimo and Aureli, Massimo and Mauri, Laura and Mauri, Laura and Ciampa, Maria Grazia and Ciampa, Maria Grazia and Prinetti, Alessandro and Prinetti, Alessandro and Toffano, Gino and Toffano, Gino and Secchieri, Cynthia and Secchieri, Cynthia and Sonnino, Sandro and Sonnino, Sandro
Molecular neurobiology, ISSN 0893-7648, 4/2016, Volume 53, Issue 3, pp. 1824 - 1842
Neurology | Neurosciences | GM1 Chemistry and Physico-chemistry | GM1 and the neurodegenerative diseases | Biomedicine | Neurobiology | GM1 | GM1 and Cholera toxin | Cellular organization of GM1 | Cell Biology | Neurotrophic and neuroprotective properties of GM1 | GM1 and GBS | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neuroprotective Agents - therapeutic use | Animals | Neuroprotective Agents - pharmacology | Cholera Toxin - metabolism | Humans | Terminology as Topic | G(M1) Ganglioside - therapeutic use | G(M1) Ganglioside - chemistry | Neurodegenerative Diseases - drug therapy | G(M1) Ganglioside - metabolism | G(M1) Ganglioside - pharmacology | Autoimmunity | Nervous system diseases | Autoantibodies | Cholera | Cholera toxin | Gangliosides | Organic acids | Brain | Biochemistry | Cellular biology | Neurons | Index Medicus
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2. Full Text Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes
by Hong, Soyon and Ostaszewski, Beth L and Yang, Ting and O’Malley, Tiernan T and Jin, Ming and Yanagisawa, Katsuhiko and Li, Shaomin and Bartels, Tim and Selkoe, Dennis J
Neuron (Cambridge, Mass.), ISSN 0896-6273, 04/2014, Volume 82, Issue 2, pp. 308 - 319
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Age Factors | Embryo, Mammalian | Amyloid beta-Peptides - pharmacology | Humans | Peptide Fragments - pharmacology | Hippocampus - drug effects | Alzheimer Disease - pathology | Gangliosides - genetics | Brain - metabolism | Dose-Response Relationship, Drug | Gangliosides - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Peptides - cerebrospinal fluid | Cell Membrane - metabolism | Peptide Fragments - metabolism | G(M1) Ganglioside - genetics | Peptide Fragments - cerebrospinal fluid | Mice, Inbred C57BL | Mice, Transgenic | Alzheimer Disease - cerebrospinal fluid | Mutation - genetics | Extracellular Fluid - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Brain - pathology | Mice | Hippocampus - physiology | In Vitro Techniques | G(M1) Ganglioside - metabolism | Index Medicus
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3. Full Text Deficiency of ganglioside GM1 correlates with Parkinson's disease in mice and humans
by Wu, Gusheng and Lu, Zi‐Hua and Kulkarni, Neil and Ledeen, Robert W
Journal of neuroscience research, ISSN 0360-4012, 10/2012, Volume 90, Issue 10, pp. 1997 - 2008
GM1 ganglioside | Parkinson's disease | heterozygous model | LIGA‐20 | GM1 deficiency | Heterozygous model | LIGA-20 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Immunohistochemistry | Tyrosine 3-Monooxygenase - metabolism | Antiparkinson Agents - pharmacology | G(M1) Ganglioside - deficiency | Cell Count | Humans | G(M1) Ganglioside - therapeutic use | Male | Gangliosides - metabolism | N-Acetylgalactosaminyltransferases - genetics | Aged, 80 and over | Dopaminergic Neurons - physiology | Female | Dopamine - analysis | Dopamine - metabolism | Levodopa - pharmacology | Parkinson Disease - pathology | 3,4-Dihydroxyphenylacetic Acid - metabolism | G(M1) Ganglioside - genetics | Mice, Inbred C57BL | Parkinson Disease - genetics | Synucleins - metabolism | 3,4-Dihydroxyphenylacetic Acid - analysis | Blotting, Western | Mice, Knockout | Animals | Aging - physiology | Aged | Mice | Tyrosine | Analysis | Genetically modified organisms | Dopa | Gangliosides | Index Medicus
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4. Full Text On the mechanism of internalization of α‐synuclein into microglia: roles of ganglioside GM1 and lipid raft
by Park, Ji‐Young and Kim, Kwang Soo and Lee, Saet‐Byul and Ryu, Jae‐Sung and Chung, Kwang Chul and Choo, Young‐Kug and Jou, Ilo and Kim, Jongsun and Park, Sang Myun
Journal of neurochemistry, ISSN 0022-3042, 07/2009, Volume 110, Issue 1, pp. 400 - 411
gangliosides | endocytosis | lipid raft | α‐synuclein | microglia | Endocytosis | Lipid raft | Gangliosides | α-synuclein | Microglia | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Nervous system as a whole | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Nervous system (semeiology, syndromes) | Microglia - metabolism | Dynamins - metabolism | Dynamins - drug effects | Membrane Microdomains - metabolism | Coculture Techniques | Humans | Clathrin - drug effects | Extracellular Space - drug effects | Protein Transport - physiology | Caveolins - metabolism | Protein Transport - drug effects | Glucosyltransferases - metabolism | Extracellular Space - metabolism | Encephalitis - physiopathology | Encephalitis - metabolism | Parkinson Disease - metabolism | Caveolins - drug effects | Endopeptidase K - pharmacology | Glucosyltransferases - antagonists & inhibitors | Cell Line | Microglia - drug effects | Endocytosis - drug effects | Enzyme Inhibitors - pharmacology | Neurodegenerative Diseases - metabolism | Parkinson Disease - physiopathology | Clathrin - metabolism | G(M1) Ganglioside - pharmacology | Endocytosis - physiology | Animals | Neurodegenerative Diseases - physiopathology | Membrane Microdomains - drug effects | Endopeptidase K - metabolism | Cell Line, Tumor | Mice | alpha-Synuclein - metabolism | G(M1) Ganglioside - metabolism | Index Medicus
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5. Full Text Functional interplay between ganglioside GM1 and cross‐linking galectin‐1 induces axon‐like neuritogenesis via integrin‐based signaling and TRPC5‐dependent Ca2+ influx
by Wu, Gusheng and Lu, Zi‐Hua and André, Sabine and Gabius, Hans‐Joachim and Ledeen, Robert W
Journal of neurochemistry, ISSN 0022-3042, 02/2016, Volume 136, Issue 3, pp. 550 - 563
neuron | Ca2+ level | integrin | axon growth | lectin | ganglioside | level | Biochemistry & Molecular Biology | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | RNA, Small Interfering - genetics | Protein Binding - genetics | Temperature | Benzamides - pharmacokinetics | Calcium - metabolism | Integrins - genetics | Galectin 1 - genetics | Galectin 1 - metabolism | Axons - physiology | Integrins - metabolism | Tyrosine - analogs & derivatives | Protein Binding - drug effects | Tyrosine - pharmacokinetics | TRPC Cation Channels - genetics | Animals, Newborn | G(M1) Ganglioside - genetics | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Signal Transduction - genetics | Mice, Knockout | Animals | Cerebellum - cytology | TRPC Cation Channels - metabolism | Mice | G(M1) Ganglioside - metabolism | RNA, Small Interfering - metabolism | Lectins | Cellular signal transduction | Gangliosides | Integrins | Neurochemistry | Index Medicus | ORIGINAL ARTICLES | Original
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