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Journal of Biological Chemistry, ISSN 0021-9258, 11/2011, Volume 286, Issue 46, pp. 40025 - 40037
Metastasis is a key event of malignant tumor progression. The capability to metastasize depends on the ability of the cancer cell to migrate into connective... 
CADHERIN | METASTASIS | MECHANISM | TRANSENDOTHELIAL MIGRATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION FACTOR SNAIL | BARRIER FUNCTION | MUSCLE | TUMOR-CELLS | PROLIFERATION | EXPRESSION | Neoplasms - metabolism | Integrin alpha5beta1 - genetics | G-Protein-Coupled Receptor Kinase 1 - antagonists & inhibitors | Humans | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Gene Knockdown Techniques | Neoplasms - genetics | G-Protein-Coupled Receptor Kinase 1 - metabolism | MAP Kinase Kinase Kinases - antagonists & inhibitors | Cytoskeleton - pathology | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Neoplasm Invasiveness | Cytoskeleton - genetics | MAP Kinase Kinase Kinases - metabolism | Phosphatidylinositol 3-Kinases - genetics | rac1 GTP-Binding Protein - antagonists & inhibitors | Cell Line, Tumor | Cytoskeleton - metabolism | G-Protein-Coupled Receptor Kinase 1 - genetics | Endothelial Cells - pathology | Neoplasms - pathology | Endothelial Cells - enzymology | Integrin alpha5beta1 - metabolism | rac1 GTP-Binding Protein - metabolism | Cell Movement | rac1 GTP-Binding Protein - genetics | Index Medicus | Cell Migration | Cytoskeletal Remodeling Dynamics | Transendothelial Migration | Integrin | Cancer Cell Invasion | Microrheology | Molecular Biophysics | Cellular Stiffness | RNA Interference (RNAi) | Cell Surface Receptor | Endothelium
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2015, Volume 290, Issue 30, pp. 18744 - 18756
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62097 - e62097
Journal Article
Human Gene Therapy, ISSN 1043-0342, 10/2012, Volume 23, Issue 10, pp. 111 - 1115
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2016, Volume 291, Issue 49, pp. 25364 - 25374
Journal Article
Journal Article
Blood, ISSN 0006-4971, 06/2006, Volume 107, Issue 12, pp. 4770 - 4780
The blood-brain barrier (BBB) is compromised during progressive HIV-1 infection, but how this occurs is incompletely understood. We studied the integrity of... 
SIGNALING PATHWAYS | LEUKOCYTE TRANSMIGRATION | TRANSENDOTHELIAL MIGRATION | ACTIVE ANTIRETROVIRAL THERAPY | CHEMOATTRACTANT PROTEIN-1 | PLATELET-ACTIVATING-FACTOR | HUMAN-IMMUNODEFICIENCY-VIRUS | HIV-1-INFECTED MONOCYTES | HEMATOLOGY | AIDS DEMENTIA | VASCULAR ENDOTHELIAL-CADHERIN | Encephalitis, Viral - genetics | Encephalitis, Viral - virology | Tight Junctions - genetics | G-Protein-Coupled Receptor Kinase 1 - antagonists & inhibitors | Humans | Monocytes - immunology | Mutation - immunology | Cell Movement - genetics | Enzyme Activation - immunology | Occludin | Cell Movement - immunology | HIV Infections - immunology | Protein Transport - immunology | Transfection | Blood-Brain Barrier - virology | Blood-Brain Barrier - immunology | HIV Infections - genetics | HIV Infections - virology | Cells, Cultured | Claudin-5 | Membrane Proteins - immunology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Down-Regulation - genetics | Protein Transport - genetics | Cell Movement - drug effects | Monocytes - virology | HIV-1 - immunology | Tight Junctions - immunology | Down-Regulation - immunology | G-Protein-Coupled Receptor Kinase 1 - genetics | G-Protein-Coupled Receptor Kinase 1 - immunology | Protein Kinase Inhibitors - pharmacology | Enzyme Activation - genetics | Encephalitis, Viral - immunology | Index Medicus | Abridged Index Medicus | Immunobiology
Journal Article
Human Gene Therapy, ISSN 1043-0342, 02/2013, Volume 24, Issue 2, pp. 189 - 202
Mutations in GUCY2D are associated with recessive Leber congenital amaurosis-1 (LCA1). GUCY2D encodes photoreceptor-specific, retinal guanylate cyclase-1... 
Research Articles | OCULAR SUBRETINAL INJECTION | RETINAL DEGENERATION | MEDICINE, RESEARCH & EXPERIMENTAL | LINKED JUVENILE RETINOSCHISIS | OPTICAL COHERENCE TOMOGRAPHY | RHODOPSIN KINASE PROMOTER | LONG-TERM PRESERVATION | ADENOASSOCIATED VIRAL VECTORS | CONE-ROD DYSTROPHY | VISUAL FUNCTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | PHOTORECEPTOR DEGENERATION | Leber Congenital Amaurosis - pathology | Dependovirus - genetics | Genetic Vectors - administration & dosage | Humans | Retinal Cone Photoreceptor Cells - enzymology | Retina - enzymology | G-Protein-Coupled Receptor Kinase 1 - metabolism | Retinal Cone Photoreceptor Cells - pathology | Retinal Rod Photoreceptor Cells - enzymology | Receptors, Cell Surface - administration & dosage | Leber Congenital Amaurosis - therapy | Guanylate Cyclase - administration & dosage | Gene Transfer Techniques | Promoter Regions, Genetic | Dependovirus - metabolism | Tomography, Optical Coherence | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Guanylate Cyclase - metabolism | Mice, Knockout | Animals | Maze Learning | G-Protein-Coupled Receptor Kinase 1 - genetics | Guanylate Cyclase - genetics | Mice | Enzyme Activation | Retina - pathology | Retinal Rod Photoreceptor Cells - pathology | Genetic Therapy - methods | Receptors, Cell Surface - genetics | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 04/2014, Volume 23, Issue 8, pp. 2164 - 2175
The molecular chaperone Hsp90 is important for the functional maturation of many client proteins, and inhibitors are in clinical trials for multiple... 
LEBER CONGENITAL AMAUROSIS | GENE | MUTANT RHODOPSIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEAT-SHOCK RESPONSE | MOUSE MODEL | KINASE | GENETICS & HEREDITY | RHODOPSIN-ARRESTIN COMPLEXES | CGMP PHOSPHODIESTERASE | QUALITY-CONTROL | DOMINANT RETINITIS-PIGMENTOSA | Retina - drug effects | Retina - metabolism | Vision, Ocular - drug effects | Rhodopsin - metabolism | Immunoenzyme Techniques | Vision, Ocular - physiology | Genes, Dominant | G-Protein-Coupled Receptor Kinase 1 - metabolism | Female | HSP90 Heat-Shock Proteins - genetics | Real-Time Polymerase Chain Reaction | Electroretinography | Genetic Predisposition to Disease | Rats, Transgenic | Tomography, Optical Coherence | Mice, Inbred C57BL | RNA, Messenger - genetics | Cells, Cultured | Rats | Retinitis Pigmentosa - genetics | Pyrimidines - pharmacology | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Retinitis Pigmentosa - prevention & control | Animals | Rhodopsin - genetics | HSP90 Heat-Shock Proteins - antagonists & inhibitors | G-Protein-Coupled Receptor Kinase 1 - genetics | HSP90 Heat-Shock Proteins - metabolism | Mice | Retina - pathology | Retinitis Pigmentosa - pathology | Pyridones - pharmacology | Index Medicus | Rhodopsin-arrestin complexes | Molecular genetics | Oftalmologia | Ciències de la salut | Dominant retinitis-pigmentosa | Mutant rhodopsin CGMP Phosphediesterase | Heat-shock response | Gene | Genètica molecular | Quality-control | Kinase | Leber congenital amaurosis | Mouse model | Ophthalmology | Medicina | Àrees temàtiques de la UPC
Journal Article
Molecular Therapy, ISSN 1525-0016, 08/2017, Volume 25, Issue 8, pp. 1866 - 1880
Journal Article
Biochemical Journal, ISSN 0264-6021, 04/2011, Volume 435, Issue 2, pp. 441 - 450
Journal Article