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Cell, ISSN 0092-8674, 2004, Volume 118, Issue 6, pp. 699 - 713
DNA repair is an essential process for preserving genome integrity in all organisms. In eukaryotes, recombinational repair is choreographed by multiprotein... 
MRE11 COMPLEX | TELOMERE MAINTENANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOUBLE-STRAND BREAKS | S-PHASE | NUCLEAR FOCI | STALLED REPLICATION FORKS | HOMOLOGOUS RECOMBINATION | SENSITIVE MUTANTS | SACCHAROMYCES-CEREVISIAE | RAD52 PROTEIN | CELL BIOLOGY | Gamma Rays | Hydroxyurea - pharmacology | G2 Phase - genetics | Saccharomyces cerevisiae - genetics | Protein-Serine-Threonine Kinases | DNA Repair - genetics | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Time Factors | Endodeoxyribonucleases - metabolism | Cell Cycle Proteins - genetics | DNA Damage - genetics | Recombination, Genetic - genetics | Genes, cdc - physiology | Gene Expression Regulation, Fungal - genetics | Exodeoxyribonucleases - genetics | Replication Protein A | Saccharomyces cerevisiae - radiation effects | Oxidative Stress - genetics | Intracellular Signaling Peptides and Proteins | DNA - metabolism | Fungal Proteins - genetics | Reaction Time - genetics | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | S Phase - genetics | DNA - genetics | Transcription Factors - metabolism | Endodeoxyribonucleases - genetics | Endonucleases | Exodeoxyribonucleases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Fungal Proteins - metabolism | Genetic research | DNA replication | Genomes | Research | DNA repair
Journal Article
MOLECULAR CELL, ISSN 1097-2765, 05/2004, Volume 14, Issue 4, pp. 501 - 513
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2011, Volume 108, Issue 50, pp. 20119 - 20124
Natural killer cell lymphoma (NKCL) constitutes a rare and aggressive form of non-Hodgkin lymphoma, and there is little insight into its pathogenesis. Here we... 
B lymphocytes | T cell lymphoma | B cell lymphoma | Cell lines | Cell cycle | Tumor suppressor genes | Natural killer cells | Methylation | Tumors | Apoptosis | Neoplastic transformation | NK-cell activation and homeostasis | Biotage pyrosequencing | CCNG2 | CCNG1 | PERIPHERAL T | LYMPHOMA/LEUKEMIA | biotage pyrosequencing | MULTIDISCIPLINARY SCIENCES | neoplastic transformation | TRANSCRIPTIONAL REPRESSOR BLIMP-1 | T-CELL | IDENTIFICATION | CONSISTENT PATTERNS | LYMPHOMA | DIFFERENTIATION | COMPARATIVE GENOMIC HYBRIDIZATION | LYMPHOCYTES | G2 Phase - genetics | Gene Silencing - drug effects | Apoptosis - drug effects | Humans | Killer Cells, Natural - pathology | Promoter Regions, Genetic - genetics | G2 Phase - drug effects | Lymphoma, Non-Hodgkin - pathology | Gene Knockdown Techniques | Time Factors | DNA Mutational Analysis | Tumor Suppressor Proteins - genetics | DNA Copy Number Variations - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Repressor Proteins - metabolism | Cell Division - genetics | Interleukin-2 - metabolism | Tumor Suppressor Proteins - metabolism | Transduction, Genetic | Repressor Proteins - genetics | DNA Copy Number Variations - genetics | DNA Methylation - genetics | Lymphoma, Non-Hodgkin - genetics | Cell Division - drug effects | Biopsy | Culture Media - pharmacology | Interleukin-2 - pharmacology | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | DNA Methylation - drug effects | Positive Regulatory Domain I-Binding Factor 1 | RNA, Small Interfering - metabolism | Development and progression | Killer cells | Genetic aspects | Non-Hodgkin's lymphomas | Health aspects | Life Sciences | Biochemistry, Molecular Biology | Biological Sciences
Journal Article
Journal Article
Journal Article
Genes and Development, ISSN 0890-9369, 03/2005, Volume 19, Issue 5, pp. 570 - 582
Journal Article
Cell Cycle, ISSN 1538-4101, 07/2003, Volume 2, Issue 4, pp. 315 - 323
Mammalian DNA replication is an elegantly choreographed process in which multiple components are assembled at the origins to form the prereplication complex.... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | checkpoints | DNA replication | cyclin | cell cycle | DNA damage | CELL BIOLOGY | G2 Phase - genetics | Phosphorylation | Cyclin-Dependent Kinases - metabolism | Origin Recognition Complex | Saccharomyces cerevisiae - genetics | Xenopus - genetics | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Cyclin-Dependent Kinase 2 | DNA Damage - physiology | Chromatin - physiology | Endodeoxyribonucleases - metabolism | Cell Cycle Proteins - genetics | DNA Damage - genetics | Exodeoxyribonucleases - genetics | G1 Phase - genetics | Cyclin-Dependent Kinases - genetics | Protein-Serine-Threonine Kinases - metabolism | G2 Phase - physiology | Retinoblastoma Protein - metabolism | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | CDC2-CDC28 Kinases - metabolism | Ataxia Telangiectasia Mutated Proteins | Saccharomyces cerevisiae Proteins - genetics | Xenopus Proteins | DNA-Binding Proteins - genetics | G1 Phase - physiology | S Phase - genetics | Protein Interaction Mapping | Endodeoxyribonucleases - genetics | Replication Origin - genetics | Animals | Xenopus - metabolism | DNA Replication - physiology | Retinoblastoma Protein - genetics | Replication Origin - physiology | Exodeoxyribonucleases - metabolism | Saccharomyces cerevisiae Proteins - metabolism | DNA Replication - genetics | S Phase - physiology | CDC2-CDC28 Kinases - genetics | Chromatin - genetics | Tumor Suppressor Proteins
Journal Article
Journal Article
Development, ISSN 0950-1991, 06/2008, Volume 135, Issue 11, pp. 2013 - 2022
The COP9 signalosome (CSN) is required for the full activity of cullin-RING E3 ubiquitin ligases (CRLs) in eukaryotes. CSN exerts its function on CRLs by... 
COP9 signalosome | Cell cycle | DNA Damage | cell cycle | ASPERGILLUS-NIDULANS | DNA damage | DNA-DAMAGE RESPONSE | DOUBLE-STRAND BREAKS | CELL-PROLIFERATION | DEVELOPMENTAL BIOLOGY | MEDIATING LIGHT CONTROL | S-PHASE | COP9/SIGNALOSOME SUBUNITS | IONIZING-RADIATION | AUXIN RESPONSE | E3 UBIQUITIN LIGASE | Protein Kinases - metabolism | Cell Cycle - genetics | Genomic Instability | G2 Phase - genetics | Protein Kinases - genetics | Oligonucleotide Array Sequence Analysis | Peptide Hydrolases - genetics | Ubiquitins - genetics | Plant Roots - genetics | Seedlings - genetics | Immunoblotting | Multiprotein Complexes - genetics | Seedlings - growth & development | Arabidopsis Proteins - metabolism | Multiprotein Complexes - metabolism | Cyclin B - genetics | Flow Cytometry | ATP-Binding Cassette Transporters - genetics | Gene Expression Regulation, Developmental | Gene Expression Regulation, Plant | ATP-Binding Cassette Transporters - metabolism | Cullin Proteins - metabolism | Nuclear Proteins - genetics | Plant Roots - growth & development | Ubiquitins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Peptide Hydrolases - metabolism | Cell Division - genetics | In Situ Nick-End Labeling | Arabidopsis Proteins - genetics | G2 Phase - physiology | Plant Roots - metabolism | Protein-Serine-Threonine Kinases - genetics | Ubiquitin-Protein Ligases - metabolism | COP9 Signalosome Complex | Nuclear Proteins - metabolism | Cell Division - physiology | Cullin Proteins - genetics | Cell Cycle - physiology | Cyclin B - metabolism | Ubiquitin-Protein Ligases - genetics | Seedlings - metabolism
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3, p. e02443
Eukaryotes package DNA into nucleosomes that contain a core of histone proteins. During DNA replication, nucleosomes are disrupted and re-assembled with newly... 
chromatin assembly | histones | cell cycle control | DEVELOPMENTAL CONTROL | MESSENGER-RNAS | INDUCED APOPTOSIS | DROSOPHILA EMBRYOGENESIS | DNA-DAMAGE | IN-VIVO | BIOLOGY | GENE-EXPRESSION | BINDING-PROTEIN | TRANSCRIPTIONAL REGULATION | CHROMATIN ASSEMBLY FACTOR-1 | Protein Kinases - metabolism | Cell Cycle - genetics | Drosophila melanogaster - embryology | Protein Kinases - genetics | Embryo, Nonmammalian - metabolism | Chromatin Assembly and Disassembly - genetics | Embryo, Nonmammalian - embryology | Protein Tyrosine Phosphatases - metabolism | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Protein Tyrosine Phosphatases - genetics | Time Factors | Gene Expression Regulation, Developmental | Cell Cycle Proteins - genetics | cdc25 Phosphatases - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cell Line | Animals, Genetically Modified | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Nucleosomes - metabolism | Nucleosomes - genetics | cdc25 Phosphatases - genetics | S Phase - genetics | Blotting, Western | G2 Phase Cell Cycle Checkpoints - genetics | Animals | Histones - genetics | DNA Replication - genetics | Checkpoint Kinase 1 | Drosophila Proteins - genetics | Histones - metabolism | Mutation | Medical research | Chromatin | Mitosis | DNA damage | G2 phase | Cell division | Genomes | Gene expression | Phosphatase | Embryos | DNA repair | Chromatin remodeling | DNA biosynthesis | Proteins | S phase | Cdc25 phosphatase | Cell cycle | Histones | Nucleosomes | Deoxyribonucleic acid--DNA
Journal Article
Journal Article