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Journal of Biological Chemistry, ISSN 0021-9258, 12/2016, Volume 291, Issue 52, pp. 26670 - 26685
In the HIV-1 replication cycle, the endosomal sorting complex required for transport (ESCRT) machinery promotes viral budding and release in the late stages.... 
Pregnancy Proteins - chemistry | Hemeproteins - genetics | Transcription Factors - chemistry | Humans | Pregnancy Proteins - genetics | Endosomal Sorting Complexes Required for Transport - genetics | Crystallography, X-Ray | Pregnancy Proteins - metabolism | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | HIV-1 - physiology | Hemeproteins - chemistry | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Endosomal Sorting Complexes Required for Transport - chemistry | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Hemeproteins - metabolism | Apoptosis Regulatory Proteins - chemistry | HIV Infections - virology | Cell Cycle Proteins - metabolism | Crystallization | Endosomal Sorting Complexes Required for Transport - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Apoptosis Regulatory Proteins - metabolism | Protein Transport | Transcription Factors - metabolism | Protein Binding | Protein Conformation | HeLa Cells | Virus Replication - physiology | Apoptosis | Calcium-Binding Proteins - genetics | HIV Infections - metabolism | viral replication | inhibition mechanism | Microbiology | human immunodeficiency virus (HIV) | ALG-2 | crystal structure | Gag expression | protein-protein interaction | transport
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2012, Volume 109, Issue 11, pp. 4146 - 4151
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0131074
The down-modulation of the beta-catenin antagonist Chibby 1 (CBY1) associated with the BCR-ABL1 fusion gene of chronic myeloid leukemia (CML) contributes to... 
PROGENITOR CELLS | BCR | STEM-CELLS | ACTIVATION | PROTEIN | C-ABL | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | IMATINIB | PREVENTS | CML STEM | Phosphorylation | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Oncogene Protein p65(gag-jun) | Gene Expression Regulation, Leukemic - genetics | Nuclear Proteins - biosynthesis | Biomarkers, Tumor - metabolism | Benzamides - pharmacology | Protein Stability | Neoplasm Proteins - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Pyrazoles - pharmacology | Carrier Proteins - biosynthesis | Down-Regulation | Subcellular Fractions - metabolism | Amino Acid Motifs | Protein Interaction Mapping | 14-3-3 Proteins - metabolism | Carrier Proteins - genetics | beta Catenin - antagonists & inhibitors | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Protein Binding | Sumoylation | Protein Processing, Post-Translational | Proteasome Endopeptidase Complex - metabolism | Exoribonucleases - metabolism | Fusion Proteins, bcr-abl - metabolism | Ubiquitin | Transcription factors | Transcription | Leukemia | Serine | Medical records | Clinical trials | AKT protein | Kinases | Medical schools | Proteins | SUMO protein | Ethics | β-catenin | Hematopoiesis | Modulation | Cell cycle | DNA methylation | Bone marrow | Fusion protein | Protein-tyrosine kinase | Binding | Tyrosine | Stability | Hematology | Myeloid leukemia | Adapters | c-Jun protein | Chronic myeloid leukemia | Hemopoiesis | Medicine | 14-3-3 protein | Stem cells | Ligands | Aberration | Methylation | Apoptosis
Journal Article
eLife, ISSN 2050-084X, 07/2016, Volume 5, Issue 2016
Journal Article
Cell, ISSN 0092-8674, 01/2018, Volume 172, Issue 1-2, pp. 262 - 274.e11
Journal Article
PLoS Pathogens, ISSN 1553-7366, 10/2010, Volume 6, Issue 10, p. e1001153
The membrane scission event that separates nascent enveloped virions from host cell membranes often requires the ESCRT pathway, which can be engaged through... 
BINDING DOMAINS | ESCRT-III | PARTICLE RELEASE | EAP45-GLUE DOMAIN | MICROBIOLOGY | MULTIVESICULAR BODY PATHWAY | VIROLOGY | STRUCTURAL BASIS | IMMUNODEFICIENCY-VIRUS TYPE-1 | ROUS-SARCOMA-VIRUS | PROTEIN-SORTING PATHWAY | EARLY ENDOSOMES | PARASITOLOGY | Ankyrin Repeat - physiology | Protein Binding - genetics | Coenzymes - genetics | Ubiquitins - genetics | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Viral Proteins - metabolism | Gene Products, gag - chemistry | Coenzymes - metabolism | Transfection | Virus Release - genetics | Viral Proteins - physiology | Cell Cycle Proteins - genetics | Spumavirus - physiology | Ubiquitins - metabolism | Calcium-Binding Proteins - metabolism | Gene Products, gag - genetics | Viral Proteins - chemistry | Cell Cycle Proteins - metabolism | Cells, Cultured | Endosomal Sorting Complexes Required for Transport - metabolism | Ubiquitin-Protein Ligases - metabolism | Viral Proteins - genetics | Spumavirus - metabolism | Protein Structure, Tertiary - genetics | Gene Products, gag - metabolism | Amino Acid Motifs - physiology | Ankyrin Repeat - genetics | Models, Biological | Calcium-Binding Proteins - physiology | Virus Release - physiology | Amino Acid Motifs - genetics | Ubiquitin-Protein Ligases - genetics | Cell Cycle Proteins - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Calcium-Binding Proteins - genetics | Protein Binding - physiology | Protein Structure, Tertiary - physiology | Ubiquitin | Research | Properties | Binding proteins | Ligases | Viral genetics | Proteins | Cell division | Plasmids
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 03/2013, Volume 110, Issue 10, pp. E861 - E868
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 8, Issue 1, pp. 25 - 33
Journal Article
Journal of Virology, ISSN 0022-538X, 06/2000, Volume 74, Issue 12, pp. 5395 - 5402
Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
IN-VITRO | VIROLOGY | ROUS-SARCOMA VIRUS | MAJOR HOMOLOGY REGION | FUNCTIONAL DOMAINS | NUCLEOCAPSID PROTEIN | INFECTED-CELLS | MUTATIONAL ANALYSIS | MATRIX DOMAIN | GCN4 LEUCINE-ZIPPER | VIRION MORPHOGENESIS | Fungal Proteins - chemistry | Protein Kinases - metabolism | Protein Kinases - genetics | Molecular Weight | gag Gene Products, Human Immunodeficiency Virus | Protein Precursors - chemistry | Humans | Leucine Zippers | HIV Protease - genetics | Protein Kinases - chemistry | Structure-Activity Relationship | Recombinant Fusion Proteins - metabolism | Gene Products, gag - chemistry | HIV-1 - physiology | Time Factors | HIV-1 - chemistry | Gene Deletion | Dimerization | Peptide Fragments - genetics | DNA-Binding Proteins | Protein Structure, Tertiary | Amino Acid Sequence | Centrifugation, Density Gradient | Peptide Fragments - metabolism | Gene Products, gag - genetics | Protein Precursors - genetics | vpr Gene Products, Human Immunodeficiency Virus | Viral Regulatory and Accessory Proteins - genetics | Human Immunodeficiency Virus Proteins | Fungal Proteins - genetics | Gene Products, vpr - metabolism | Recombinant Fusion Proteins - chemistry | HIV-1 - genetics | Virus Assembly | Viral Regulatory and Accessory Proteins - metabolism | Amino Acid Motifs | Gene Products, gag - metabolism | Protein Precursors - metabolism | Myristic Acid - metabolism | Peptide Fragments - chemistry | Saccharomyces cerevisiae Proteins | Protein Binding | Recombinant Fusion Proteins - genetics | HeLa Cells | HIV Protease - metabolism | Fungal Proteins - metabolism | Structure and Assembly
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2010, Volume 432, Issue 3, pp. 525 - 534
The adaptor protein ALIX [ALG-2 (apoptosis-linked-gene-2 product)-interacting protein X] links retroviruses to ESCRT (endosomal sorting complex required for... 
Tumour susceptibility gene 101 protein (TSG101) | ALG-2 (apoptosis-linked-gene-2 product)-interacting protein X (ALIX) | Autoinhibition | Src | Charged multivesicular body protein 4 (CHMP4) | Retroviral budding | Intramolecular interaction | intramolecular interaction | HIV-1 | charged multivesicular body protein 4 (CHMP4) | ALIX/AIP1 | retroviral budding | PHOSPHORYLATION | INFECTIOUS-ANEMIA VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | autoinhibition | BRO1 DOMAIN | MULTIVESICULAR BODY BIOGENESIS | CYTOKINESIS | tumour susceptibility gene 101 protein (TSG101) | STRUCTURAL BASIS | III COMPLEX | BINDING | Oncogene Protein pp60(v-src) - metabolism | Transcription Factors - chemistry | Vesicular Transport Proteins - metabolism | Humans | Endosomal Sorting Complexes Required for Transport - genetics | Proline-Rich Protein Domains - physiology | Recombinant Fusion Proteins - metabolism | Gene Products, gag - chemistry | Cell Cycle Proteins - chemistry | DNA-Binding Proteins - metabolism | Oncogene Protein pp60(v-src) - chemistry | HEK293 Cells | Cell Cycle Proteins - genetics | Retroviridae Proteins - chemistry | Cell Membrane - metabolism | Endosomal Sorting Complexes Required for Transport - chemistry | Protein Interaction Domains and Motifs | Calcium-Binding Proteins - chemistry | Recombinant Proteins - metabolism | Gene Products, gag - genetics | Endosomal Sorting Complexes Required for Transport - metabolism | Recombinant Proteins - chemistry | Mutant Proteins - metabolism | Oncogene Protein pp60(v-src) - genetics | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Retroviridae Proteins - genetics | Gene Products, gag - metabolism | Transcription Factors - metabolism | Infectious Anemia Virus, Equine - physiology | Retroviridae Proteins - metabolism | Calcium-Binding Proteins - physiology | Mutant Proteins - chemistry | Virus Release - physiology | Hydrophobic and Hydrophilic Interactions | Cell Cycle Proteins - physiology | Endosomal Sorting Complexes Required for Transport - physiology | Calcium-Binding Proteins - genetics | TSG101 | ALIX | CHMP4
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2013, Volume 9, Issue 7, p. e1003483
Tetherin, an interferon-inducible membrane protein, inhibits the release of nascent enveloped viral particles from the surface of infected cells. However, the... 
INHIBITS HIV-1 | PROTEIN | IMMUNODEFICIENCY-VIRUS | PARTICLE RELEASE | DOWN-REGULATION | MICROBIOLOGY | RESTRICTION | BST-2/TETHERIN | INTERFERON-ALPHA | VIROLOGY | SURFACE | VPU | PARASITOLOGY | Humans | Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase - metabolism | Antiviral Agents - metabolism | Antigens, CD - genetics | Recombinant Fusion Proteins - metabolism | Antigens, CD - metabolism | HIV-1 - physiology | Glycosylphosphatidylinositols - chemistry | Antiviral Agents - chemistry | Proteolysis | HEK293 Cells | Antigens, CD - chemistry | Protein Interaction Domains and Motifs | Dimerization | Peptide Fragments - genetics | Virion - immunology | gag Gene Products, Human Immunodeficiency Virus - biosynthesis | Peptide Fragments - metabolism | Viral Regulatory and Accessory Proteins - genetics | Virion - physiology | Recombinant Fusion Proteins - chemistry | GPI-Linked Proteins - metabolism | Viral Regulatory and Accessory Proteins - metabolism | Human Immunodeficiency Virus Proteins - metabolism | HIV-1 - immunology | Peptide Fragments - chemistry | GPI-Linked Proteins - chemistry | Glycosylphosphatidylinositols - metabolism | Models, Biological | Virus Attachment | Human Immunodeficiency Virus Proteins - genetics | Protein Conformation | HeLa Cells | Mutation | GPI-Linked Proteins - genetics | Viral proteins | Physiological aspects | Virulence (Microbiology) | Research | HIV (Viruses) | Health aspects | Membrane proteins | Proteins | Viruses | Interferon | Experiments
Journal Article