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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue 20, pp. 2111 - 2112
In this issue of Blood, Ueki et al elegantly demonstrate the active formation of Charcot-Leyden crystals (CLCs) during eosinophil cytolysis.(1) After... 
HEMATOLOGY | GALECTIN-10 | T-CELLS
Journal Article
Journal Article
Glycobiology, ISSN 0959-6658, 03/2018, Volume 28, Issue 3, pp. 159 - 168
Abstract Galectin-10 (Gal-10) which forms Charcot-Leyden crystals in vivo, is crucial to regulating lymph cell function. Here, we solved the crystal structures... 
site-directed mutagenesis | Charcot-Leyden crystal | Galectin-10 homodimer | carbohydrate-binding domain | LEYDEN CRYSTAL PROTEIN | X-RAY CRYSTALLOGRAPHY | RECOGNITION | EOSINOPHILS | BIOCHEMISTRY & MOLECULAR BIOLOGY | LACTOSE | ACUTE MYELOID-LEUKEMIA | FAMILY | LYSOPHOSPHOLIPASE | BONE-MARROW NECROSIS | ANIMAL LECTINS
Journal Article
Allergy & Rhinology, ISSN 2152-6575, 8/2019, Volume 10, p. 2152656719869607
Background Eosinophilic cholecystitis (EC) is a rare condition that presents in a manner comparable to acute cholecystitis. The diagnosis is based on classical... 
Journal Article
Allergy, ISSN 0105-4538, 09/2017, Volume 72, Issue 9, pp. 1406 - 1414
Journal Article
Current Allergy and Asthma Reports, ISSN 1529-7322, 8/2019, Volume 19, Issue 8, pp. 1 - 9
Charcot-Leyden crystals (CLCs), slender bipyramidal hexagonal crystals, were first described by Jean-Martin Charcot in 1853, predating Paul Ehrlich’s... 
Allergology | Charcot-Leyden crystal | Medicine & Public Health | Degranulation | Extracellular traps | Eosinophils | Galectin-10 | ACTIVATION | ULTRASTRUCTURAL-LOCALIZATION | BIOCHEMICAL-CHARACTERIZATION | IMMUNOLOGY | GRANULES | CELL-DEATH | NEUTROPHIL EXTRACELLULAR TRAPS | ALLERGY | PROTEIN LYSOPHOSPHOLIPASE | T-CELLS | Lectins | Medical colleges | Chromatin | Inflammation | Cell death | Analysis
Journal Article
BIOMARKERS IN MEDICINE, ISSN 1752-0363, 06/2019, Volume 13, Issue 9, pp. 715 - 724
Eosinophilic asthma is associated with more exacerbations and differential responses to treatment. The aim of this study was to assess if CLC/Gal-10 and MBP-1... 
MEDICINE, RESEARCH & EXPERIMENTAL | CATIONIC PROTEIN | asthma | sputum | PHENOTYPES | biomarker | LYSOPHOSPHOLIPASE | PEROXIDASE | INDUCED SPUTUM | GALECTIN-10 | GRANULE | EXACERBATIONS | DEGRANULATION | eosinophil | MAJOR BASIC-PROTEIN
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0126582
Background IgG4-related disease (IgG4-RD) is a new clinical entity of unknown etiology characterized by elevated serum IgG4 and tissue infiltration by... 
IN-VITRO | ACTIVATION | NEUTROPHIL | MESSENGER-RNA | AUTOIMMUNE PANCREATITIS | GALECTIN-10 | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | MICE | ANTIMICROBIAL PEPTIDES | TH2 | Receptors, Interleukin-8 - genetics | Leukocytes, Mononuclear - metabolism | Up-Regulation | Immunoglobulin G - blood | Oligonucleotide Array Sequence Analysis | Lysophospholipase - metabolism | Humans | Middle Aged | Glycoproteins - metabolism | Immunity, Innate - genetics | Male | Th2 Cells - immunology | Case-Control Studies | alpha-Defensins - genetics | Leukocytes, Mononuclear - immunology | Lysophospholipase - genetics | Aged, 80 and over | Cell Cycle Proteins - genetics | Adult | Female | alpha-Defensins - metabolism | Membrane Proteins - metabolism | Autoimmune Diseases - pathology | Real-Time Polymerase Chain Reaction | Glycoproteins - genetics | Receptors, Interleukin-8 - metabolism | Membrane Proteins - genetics | Down-Regulation | Autoimmune Diseases - immunology | Cell Cycle Proteins - metabolism | Th2 Cells - cytology | Leukocytes, Mononuclear - cytology | Aged | Care and treatment | DNA microarrays | Immunological deficiency syndromes | Development and progression | Genetic aspects | Research | Risk factors | Therapy | Control methods | Pathogenesis | Immunoglobulin G | Genes | Interleukin | Leukocytes (mononuclear) | Innate immunity | Lymphocytes T | Interleukin 8 receptors | Immunity | Blood | Proteins | Receptors | Immunology | Etiology | Gastroenterology | Cell cycle | Peripheral blood mononuclear cells | Interleukin 8 | Deoxyribonucleic acid--DNA | Immune system | Medical research | Hematology | Cytokines | Internal medicine | Abnormalities | Hypersensitivity | Neutrophils | Rheumatology | Pancreatitis | Inflammation | Gene expression | Real time | Ribonucleic acid--RNA | Patients | Membrane proteins | Asthma | Medicine | Polymerase chain reaction | Hospitals | Plasma cells | Infiltration | Aberration | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2014, Volume 20, Issue 12, pp. 1891 - 1898
Journal Article
PROTEOMICS – Clinical Applications, ISSN 1862-8346, 10/2009, Volume 3, Issue 10, pp. 1151 - 1173
Eosinophils (EOSs) are granular leukocytes that have significant roles in many inflammatory and immunoregulatory responses, especially asthma and allergic... 
2‐DE | Protein expression | Phosphoproteins | Asthma | Eosinophils | 2-DE | LEYDEN CRYSTAL PROTEIN | SURVIVAL | ACTIVATION | ACTIN | PHOSPHORYLATION | BIOCHEMICAL RESEARCH METHODS | LYSOPHOSPHOLIPASE | GALECTIN-10
Journal Article
Allergy, ISSN 0105-4538, 02/2010, Volume 65, Issue 2, pp. 220 - 228
Journal Article
Journal Article