Clinical Microbiology and Infection, ISSN 1198-743X, 07/2011, Volume 17, Issue 7, pp. 986 - 995
Human African trypanosomiasis (HAT), or sleeping sickness, is a vector-borne disease that flourishes in impoverished, rural parts of sub-Saharan Africa. It is...
Human African trypanosomiasis | Trypanosoma brucei gambiense | review | tsetse | Trypanosoma brucei rhodesiense | sleeping sickness | Sleeping sickness | Review | Tsetse | DIAGNOSIS | INFECTIOUS DISEASES | CONFIRMATION | FOLLOW-UP | MICROBIOLOGY | CEREBROSPINAL-FLUID | MELARSOPROL | EFLORNITHINE | BRUCEI-GAMBIENSE | SURVEILLANCE | CARD-AGGLUTINATION-TEST | Tsetse Flies - parasitology | Humans | Neglected Diseases - pathology | Communicable Disease Control - methods | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Neglected Diseases - diagnosis | Trypanosoma brucei brucei - pathogenicity | Trypanosomiasis, African - epidemiology | Neglected Diseases - epidemiology | Trypanosomiasis, African - pathology | Disease Vectors | Africa South of the Sahara - epidemiology | Neglected Diseases - parasitology | Trypanosoma brucei brucei - immunology | Chemotherapy | Disease transmission | Universities and colleges | Health aspects | Trypanosomiasis | Cancer
Human African trypanosomiasis | Trypanosoma brucei gambiense | review | tsetse | Trypanosoma brucei rhodesiense | sleeping sickness | Sleeping sickness | Review | Tsetse | DIAGNOSIS | INFECTIOUS DISEASES | CONFIRMATION | FOLLOW-UP | MICROBIOLOGY | CEREBROSPINAL-FLUID | MELARSOPROL | EFLORNITHINE | BRUCEI-GAMBIENSE | SURVEILLANCE | CARD-AGGLUTINATION-TEST | Tsetse Flies - parasitology | Humans | Neglected Diseases - pathology | Communicable Disease Control - methods | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Neglected Diseases - diagnosis | Trypanosoma brucei brucei - pathogenicity | Trypanosomiasis, African - epidemiology | Neglected Diseases - epidemiology | Trypanosomiasis, African - pathology | Disease Vectors | Africa South of the Sahara - epidemiology | Neglected Diseases - parasitology | Trypanosoma brucei brucei - immunology | Chemotherapy | Disease transmission | Universities and colleges | Health aspects | Trypanosomiasis | Cancer
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 10/2012, Volume 6, Issue 10, p. e1859
Background: Human African trypanosomiasis (HAT), also known as sleeping sickness, persists as a public health problem in several sub-Saharan countries....
ATLAS | HUMAN AFRICAN TRYPANOSOMIASIS | CLIMATE-CHANGE | PREVALENCE | EPIDEMIOLOGY | VILLAGES | PARASITOLOGY | TROPICAL MEDICINE | UGANDA | Africa South of the Sahara | Risk Assessment | Epidemiologic Methods | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - epidemiology | Care and treatment | Demographic aspects | Research | Health risk assessment | Trypanosomiasis | Medical geography | Risk factors | Methods | Animal diseases | Population | Maps | Estimates
ATLAS | HUMAN AFRICAN TRYPANOSOMIASIS | CLIMATE-CHANGE | PREVALENCE | EPIDEMIOLOGY | VILLAGES | PARASITOLOGY | TROPICAL MEDICINE | UGANDA | Africa South of the Sahara | Risk Assessment | Epidemiologic Methods | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - epidemiology | Care and treatment | Demographic aspects | Research | Health risk assessment | Trypanosomiasis | Medical geography | Risk factors | Methods | Animal diseases | Population | Maps | Estimates
Journal Article
Journal of Neurology, ISSN 0340-5354, 2019, Volume 266, Issue 9, pp. 2334 - 2337
Human African trypanosomiasis (HAT), also known as sleeping sickness, is one of the Africa's 'neglected diseases' and is caused by infection with protozoan...
Sleeping sickness | Diagnostic staging | Parasite | CNS | Human African trypanosomiasis | Sub-Saharan Africa | Tsetse fly | ISSUES | MULTICENTER | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | CLINICAL NEUROLOGY | Neuropathogenesis | Parasites | Disease | African trypanosomiasis
Sleeping sickness | Diagnostic staging | Parasite | CNS | Human African trypanosomiasis | Sub-Saharan Africa | Tsetse fly | ISSUES | MULTICENTER | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | CLINICAL NEUROLOGY | Neuropathogenesis | Parasites | Disease | African trypanosomiasis
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2013, Volume 368, Issue 11, pp. 1069 - 1070
Sleeping sickness, or human African trypanosomiasis, is a potentially life-threatening vectorborne disease of sub-Saharan Africa. Data on a prototype rapid...
MEDICINE, GENERAL & INTERNAL | GAMBIENSE | HUMAN AFRICAN TRYPANOSOMIASIS | AGGLUTINATION-TEST | Trypanosomiasis, African - immunology | Diagnostic Tests, Routine | Antibodies, Protozoan - blood | Trypanosomiasis, African - diagnosis | Trypanosomiasis, African - blood | Humans | Sensitivity and Specificity | Trypanosoma brucei gambiense - immunology | Plasma | Antigens | Infections | Trypanosomiasis | Diagnostic tests | African trypanosomiasis
MEDICINE, GENERAL & INTERNAL | GAMBIENSE | HUMAN AFRICAN TRYPANOSOMIASIS | AGGLUTINATION-TEST | Trypanosomiasis, African - immunology | Diagnostic Tests, Routine | Antibodies, Protozoan - blood | Trypanosomiasis, African - diagnosis | Trypanosomiasis, African - blood | Humans | Sensitivity and Specificity | Trypanosoma brucei gambiense - immunology | Plasma | Antigens | Infections | Trypanosomiasis | Diagnostic tests | African trypanosomiasis
Journal Article
Trends in Parasitology, ISSN 1471-4922, 03/2018, Volume 34, Issue 3, pp. 197 - 207
causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440 000 cases were reported. Large-scale screening of populations at risk, drug...
human African trypanosomiasis | transmission | reservoir | Trypanosoma brucei gambiense | elimination | sleeping sickness | PIGS | TRYPANOSOMA-BRUCEI-GAMBIENSE | TRANSMISSION | INCUBATION INFECTIVITY TEST | MODELS | HUMAN AFRICAN TRYPANOSOMIASIS | TSETSE | TRYPANOZOON | IDENTIFICATION | ANIMAL RESERVOIR | PARASITOLOGY | Life Sciences | Microbiology and Parasitology | Parasitology
human African trypanosomiasis | transmission | reservoir | Trypanosoma brucei gambiense | elimination | sleeping sickness | PIGS | TRYPANOSOMA-BRUCEI-GAMBIENSE | TRANSMISSION | INCUBATION INFECTIVITY TEST | MODELS | HUMAN AFRICAN TRYPANOSOMIASIS | TSETSE | TRYPANOZOON | IDENTIFICATION | ANIMAL RESERVOIR | PARASITOLOGY | Life Sciences | Microbiology and Parasitology | Parasitology
Journal Article
Parasitology, ISSN 0031-1820, 12/2009, Volume 136, Issue 14, pp. 1943 - 1949
Following a period characterized by severe epidemics of sleeping sickness, restoration of effective control and surveillance systems has raised the question of...
tsetse control | neglected diseases | Sleeping sickness | surveillance | EASTERN UGANDA | HUMAN AFRICAN TRYPANOSOMIASIS | RANDOMIZED CLINICAL-TRIAL | RHODESIENSE | ANIMAL RESERVOIR | TSETSE-FLY | EFLORNITHINE | BRUCEI-GAMBIENSE | LATE-STAGE | DISEASE | PARASITOLOGY | Tsetse Flies - parasitology | Humans | Trypanosoma brucei rhodesiense | Trypanosomiasis, African - prevention & control | Trypanosoma brucei gambiense | Public-Private Sector Partnerships | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Insect Vectors - parasitology | Trypanosomiasis, African - epidemiology | Africa South of the Sahara - epidemiology | Insect Control - methods | Population Surveillance - methods
tsetse control | neglected diseases | Sleeping sickness | surveillance | EASTERN UGANDA | HUMAN AFRICAN TRYPANOSOMIASIS | RANDOMIZED CLINICAL-TRIAL | RHODESIENSE | ANIMAL RESERVOIR | TSETSE-FLY | EFLORNITHINE | BRUCEI-GAMBIENSE | LATE-STAGE | DISEASE | PARASITOLOGY | Tsetse Flies - parasitology | Humans | Trypanosoma brucei rhodesiense | Trypanosomiasis, African - prevention & control | Trypanosoma brucei gambiense | Public-Private Sector Partnerships | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Insect Vectors - parasitology | Trypanosomiasis, African - epidemiology | Africa South of the Sahara - epidemiology | Insect Control - methods | Population Surveillance - methods
Journal Article
Annals of Neurology, ISSN 0364-5134, 08/2008, Volume 64, Issue 2, pp. 116 - 126
Human African trypanosomiasis, also known as sleeping sickness, is a neglected disease, and it continues to pose a major threat to 60 million people in 36...
ENCEPHALOPATHY | MELARSOPROL | BRUCEI-INFECTED MICE | COMBINATION THERAPY | STAGE DETERMINATION | GAMBIENSE | CENTRAL-NERVOUS-SYSTEM | CEREBROSPINAL-FLUID | FUTURE-PROSPECTS | NEUROSCIENCES | CLINICAL NEUROLOGY | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Tsetse Flies - parasitology | Trypanosoma brucei gambiense - drug effects | Humans | Trypanocidal Agents - therapeutic use | Trypanosoma brucei gambiense - isolation & purification | Trypanosoma brucei rhodesiense - drug effects | Trypanosoma brucei rhodesiense - isolation & purification | Index Medicus
ENCEPHALOPATHY | MELARSOPROL | BRUCEI-INFECTED MICE | COMBINATION THERAPY | STAGE DETERMINATION | GAMBIENSE | CENTRAL-NERVOUS-SYSTEM | CEREBROSPINAL-FLUID | FUTURE-PROSPECTS | NEUROSCIENCES | CLINICAL NEUROLOGY | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - diagnosis | Tsetse Flies - parasitology | Trypanosoma brucei gambiense - drug effects | Humans | Trypanocidal Agents - therapeutic use | Trypanosoma brucei gambiense - isolation & purification | Trypanosoma brucei rhodesiense - drug effects | Trypanosoma brucei rhodesiense - isolation & purification | Index Medicus
Journal Article
Implicating roles of animal reservoir hosts in the resurgence of Gambian trypanosomosis (Sleeping Sickness), 12/2005
Gambian trypanosomosis  (Sleeping Sickness) is a complex and debilitating disease of man. For many years the disease has been ravaging in several parts of...
Gambian trypanosomosis, Trypanosoma brucei gambiense, animal reservoir hosts, biotechnologies
Gambian trypanosomosis, Trypanosoma brucei gambiense, animal reservoir hosts, biotechnologies
Journal
British Journal of Hospital Medicine, ISSN 1750-8460, 10/2016, Volume 77, Issue 10, pp. C157 - C160
TRYPANOSOMIASIS | MEDICINE, GENERAL & INTERNAL | RISK | THERAPY | TRAVELERS | Trypanosoma brucei rhodesiense - physiology | Trypanosomiasis, African - drug therapy | Tsetse Flies - parasitology | Humans | Pentamidine - therapeutic use | Eflornithine - therapeutic use | Trypanosomiasis, African - transmission | Animals | Trypanosomiasis, African - diagnosis | Insect Vectors - parasitology | Suramin - therapeutic use | Trypanocidal Agents - therapeutic use | Nifurtimox - therapeutic use | Trypanosoma brucei gambiense - physiology | Trypanosomiasis, African - physiopathology
Journal Article
Lancet Neurology, The, ISSN 1474-4422, 2013, Volume 12, Issue 2, pp. 186 - 194
Summary Human African trypanosomiasis, or sleeping sickness, is caused by infection with parasites of the genus Trypanosoma , transmitted by the tsetse fly....
Neurology | HUMAN-SERUM | NERVOUS-SYSTEM | 10-DAY MELARSOPROL SCHEDULE | RISK-FACTORS | MEDIATED ISOTHERMAL AMPLIFICATION | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | LYTIC FACTOR | FOLLOW-UP | RAPID DETECTION | CLINICAL NEUROLOGY | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Trypanosomiasis, African - parasitology | Trypanosomiasis, African - diagnosis | Trypanosoma brucei rhodesiense - pathogenicity | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - epidemiology | Trypanosomiasis, African - therapy | Care and treatment | Disease transmission | Diagnosis | Trypanosomiasis | Index Medicus
Neurology | HUMAN-SERUM | NERVOUS-SYSTEM | 10-DAY MELARSOPROL SCHEDULE | RISK-FACTORS | MEDIATED ISOTHERMAL AMPLIFICATION | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | LYTIC FACTOR | FOLLOW-UP | RAPID DETECTION | CLINICAL NEUROLOGY | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Trypanosomiasis, African - parasitology | Trypanosomiasis, African - diagnosis | Trypanosoma brucei rhodesiense - pathogenicity | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - epidemiology | Trypanosomiasis, African - therapy | Care and treatment | Disease transmission | Diagnosis | Trypanosomiasis | Index Medicus
Journal Article
11.
Full Text
Assessing strategies against gambiense sleeping sickness through mathematical modeling
Clinical Infectious Diseases, ISSN 1058-4838, 06/2018, Volume 66, Issue suppl_4, pp. S286 - S292
Background. Control of gambiense sleeping sickness relies predominantly on passive and active screening of people, followed by treatment. Methods. Mathematical...
Gambiense human African trypanosomiasis | HAT | Mathematical modeling | Elimination | Intervention effectiveness | INFECTIOUS DISEASES | mathematical modeling | intervention effectiveness | MICROBIOLOGY | gambiense human African trypanosomiasis | IMMUNOLOGY | elimination | Supplement
Gambiense human African trypanosomiasis | HAT | Mathematical modeling | Elimination | Intervention effectiveness | INFECTIOUS DISEASES | mathematical modeling | intervention effectiveness | MICROBIOLOGY | gambiense human African trypanosomiasis | IMMUNOLOGY | elimination | Supplement
Journal Article
PROTEOMICS CLINICAL APPLICATIONS, ISSN 1862-8346, 07/2018, Volume 12, Issue 4
Sleeping sickness is a neglected tropical disease caused by Trypanosoma brucei parasites, affecting the poorest communities in sub-Saharan Africa. The great...
Parasite biology | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | HUMAN AFRICAN TRYPANOSOMIASIS | BIOCHEMICAL RESEARCH METHODS | "Omics | NON-INFERIORITY TRIAL | EFLORNITHINE COMBINATION THERAPY | ARSENICAL DRUG-RESISTANCE | BLOOD-STREAM FORM | Sleeping sickness | PROCYCLIC FORMS | HOST-PARASITE INTERFACE | LIFE-CYCLE STAGES | Biomarkers | Trypanosoma brucei | PROTEOMIC ANALYSIS
Parasite biology | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | HUMAN AFRICAN TRYPANOSOMIASIS | BIOCHEMICAL RESEARCH METHODS | "Omics | NON-INFERIORITY TRIAL | EFLORNITHINE COMBINATION THERAPY | ARSENICAL DRUG-RESISTANCE | BLOOD-STREAM FORM | Sleeping sickness | PROCYCLIC FORMS | HOST-PARASITE INTERFACE | LIFE-CYCLE STAGES | Biomarkers | Trypanosoma brucei | PROTEOMIC ANALYSIS
Journal Article
2012, Advances in Parasitology, ISBN 9780123984579, Volume 79, 39
Sleeping sickness describes two diseases, both fatal if left untreated: (i) Gambian sleeping sickness caused by , a chronic disease with average infection...
GLOSSINA-FUSCIPES-FUSCIPES | EQUATORIAL-GUINEA | RESTRICTED APPLICATION | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | EASTERN UGANDA | HUMAN AFRICAN TRYPANOSOMIASIS | APARASITEMIC SEROLOGICAL SUSPECTS | COTE-DIVOIRE | NEGLECTED TROPICAL DISEASES | TSETSE-FLIES GLOSSINA | PARASITOLOGY | Africa - epidemiology | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - prevention & control | Disease Eradication - methods | Communicable Disease Control - methods | Incidence | Zoonoses - transmission | Neglected Diseases - prevention & control | Neglected Diseases - mortality | Animals | Trypanosomiasis, African - diagnosis | Zoonoses - parasitology | Trypanosoma brucei rhodesiense - pathogenicity | Cattle | Neglected Diseases - diagnosis | Trypanosomiasis, African - epidemiology | Trypanosomiasis, African - mortality | Zoonoses - epidemiology | Neglected Diseases - epidemiology
GLOSSINA-FUSCIPES-FUSCIPES | EQUATORIAL-GUINEA | RESTRICTED APPLICATION | BRUCEI-GAMBIENSE TRYPANOSOMIASIS | EASTERN UGANDA | HUMAN AFRICAN TRYPANOSOMIASIS | APARASITEMIC SEROLOGICAL SUSPECTS | COTE-DIVOIRE | NEGLECTED TROPICAL DISEASES | TSETSE-FLIES GLOSSINA | PARASITOLOGY | Africa - epidemiology | Humans | Trypanosoma brucei gambiense - pathogenicity | Trypanosomiasis, African - prevention & control | Disease Eradication - methods | Communicable Disease Control - methods | Incidence | Zoonoses - transmission | Neglected Diseases - prevention & control | Neglected Diseases - mortality | Animals | Trypanosomiasis, African - diagnosis | Zoonoses - parasitology | Trypanosoma brucei rhodesiense - pathogenicity | Cattle | Neglected Diseases - diagnosis | Trypanosomiasis, African - epidemiology | Trypanosomiasis, African - mortality | Zoonoses - epidemiology | Neglected Diseases - epidemiology
Book Chapter
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 12/2011, Volume 55, Issue 12, pp. 5602 - 5608
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit...
TRYPANOSOMA-BRUCEI-GAMBIENSE | IN-VITRO | MELARSOPROL | EFLORNITHINE | HUMAN AFRICAN TRYPANOSOMIASIS | SUDAN | RHODESIENSE | CROSS-RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CULTIVATION | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Nitroimidazoles - pharmacology | Safrole - analogs & derivatives | Humans | Sulfones - metabolism | Treatment Outcome | Trypanocidal Agents - pharmacokinetics | Trypanosoma brucei brucei - drug effects | Safrole - metabolism | Trypanosomiasis, African - parasitology | Animals | Nitroimidazoles - therapeutic use | Parasitic Sensitivity Tests - methods | Trypanocidal Agents - pharmacology | Trypanosoma brucei rhodesiense - growth & development | Female | Trypanocidal Agents - therapeutic use | Mice | Trypanosoma brucei rhodesiense - drug effects | Trypanosoma brucei brucei - growth & development | Nitroimidazoles - pharmacokinetics | Nitroimidazoles - administration & dosage | Trypanocidal Agents - administration & dosage | Susceptibility
TRYPANOSOMA-BRUCEI-GAMBIENSE | IN-VITRO | MELARSOPROL | EFLORNITHINE | HUMAN AFRICAN TRYPANOSOMIASIS | SUDAN | RHODESIENSE | CROSS-RESISTANCE | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | CULTIVATION | TREATMENT FAILURE | Trypanosomiasis, African - drug therapy | Nitroimidazoles - pharmacology | Safrole - analogs & derivatives | Humans | Sulfones - metabolism | Treatment Outcome | Trypanocidal Agents - pharmacokinetics | Trypanosoma brucei brucei - drug effects | Safrole - metabolism | Trypanosomiasis, African - parasitology | Animals | Nitroimidazoles - therapeutic use | Parasitic Sensitivity Tests - methods | Trypanocidal Agents - pharmacology | Trypanosoma brucei rhodesiense - growth & development | Female | Trypanocidal Agents - therapeutic use | Mice | Trypanosoma brucei rhodesiense - drug effects | Trypanosoma brucei brucei - growth & development | Nitroimidazoles - pharmacokinetics | Nitroimidazoles - administration & dosage | Trypanocidal Agents - administration & dosage | Susceptibility
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 2015, Volume 9, Issue 8, p. e0003822
Background Gambian sleeping sickness (human African trypanosomiasis, HAT) outbreaks are brought under control by case detection and treatment although it is...
TRYPANOSOMA-BRUCEI-GAMBIENSE | COST-EFFECTIVENESS | INFECTIONS | DIPTERA | HUMAN AFRICAN TRYPANOSOMIASIS | BAITS | PALLIDIPES | FACILITATE | PARASITOLOGY | TROPICAL MEDICINE | GLOSSINA-FUSCIPES | FLIES | Kenya - epidemiology | Tsetse Flies - parasitology | Humans | Insect Control - economics | Trypanosomiasis, African - economics | Trypanosomiasis, African - prevention & control | Uganda - epidemiology | Trypanosomiasis, African - parasitology | Animals | Insect Vectors - physiology | Tsetse Flies - physiology | Insect Vectors - parasitology | Trypanosomiasis, African - epidemiology | Trypanosoma brucei gambiense - physiology | Prevention | Control | Insect pests | Health promotion | Public health administration | Trypanosomiasis | Methods | Epidemics | Insecticides | Mathematical models | Population density
TRYPANOSOMA-BRUCEI-GAMBIENSE | COST-EFFECTIVENESS | INFECTIONS | DIPTERA | HUMAN AFRICAN TRYPANOSOMIASIS | BAITS | PALLIDIPES | FACILITATE | PARASITOLOGY | TROPICAL MEDICINE | GLOSSINA-FUSCIPES | FLIES | Kenya - epidemiology | Tsetse Flies - parasitology | Humans | Insect Control - economics | Trypanosomiasis, African - economics | Trypanosomiasis, African - prevention & control | Uganda - epidemiology | Trypanosomiasis, African - parasitology | Animals | Insect Vectors - physiology | Tsetse Flies - physiology | Insect Vectors - parasitology | Trypanosomiasis, African - epidemiology | Trypanosoma brucei gambiense - physiology | Prevention | Control | Insect pests | Health promotion | Public health administration | Trypanosomiasis | Methods | Epidemics | Insecticides | Mathematical models | Population density
Journal Article