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Nature Medicine, ISSN 1078-8956, 03/2010, Volume 16, Issue 3, pp. 302 - 307
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 4, p. e10025
Background: Cells from individuals with Friedreich's ataxia (FRDA) show reduced activities of antioxidant enzymes and cannot up-regulate their expression when... 
OXIDATIVE STRESS | TRIPLET REPEAT | PROTEIN | PGC-1-ALPHA | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | TRANSCRIPTIONAL COACTIVATOR | YEAST FRATAXIN | PROMOTES MITOCHONDRIAL BIOGENESIS | MOUSE MODELS | IRON ACCUMULATION | Friedreich Ataxia - metabolism | Superoxide Dismutase - analysis | Oxidative Stress | Friedreich Ataxia - pathology | Antioxidants - metabolism | Humans | Cells, Cultured | Hydrogen Peroxide - pharmacology | Transcription Factors - genetics | PPAR gamma | Case-Control Studies | Down-Regulation - genetics | Mice, Knockout | Heat-Shock Proteins - genetics | Animals | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Mice | Cyclic AMP-Dependent Protein Kinases | Antioxidants | Enzymes | Ataxia | Superoxide | Hydrogen peroxide | Protein kinases | Cerebellum | Protein kinase A | Oxidative stress | Spinal cord | Animal models | Yeast | Transcription | Pathogenesis | Superoxide dismutase | Biosynthesis | Mitochondrial DNA | Kinases | Proteins | Mitochondria | Control | Hyperglycemia | Bioenergetics | Rodents | Down-regulation | Fibroblasts | Stress response | Deoxyribonucleic acid--DNA | Hydrogen ion concentration | Pioglitazone | siRNA | Pharmacology | Metabolism | Patients | Friedreich's ataxia | Musculoskeletal system | Protein kinase | Diabetes | Mutation | Molecular biology | Deoxyribonucleic acid | DNA
Journal Article
PLoS Biology, ISSN 1544-9173, 03/2011, Volume 9, Issue 3, p. e1000598
Journal Article
Journal Article
Journal Article
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 07/2011, Volume 121, Issue 7, pp. 2614 - 2624
Chronic immune activation in HIV-infected individuals leads to accumulation of exhausted tissue-like memory B cells. Exhausted lymphocytes display increased... 
INDIVIDUALS | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | DIFFERENTIATION | CHRONIC VIRAL-INFECTION | ANTIGEN RECEPTOR | EXPRESSION | T-CELLS | FC-GAMMA-RIIB | DISEASE PROGRESSION
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2009, Volume 379, Issue 2, pp. 406 - 410
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0148604
textabstractBackground The co-stimulatory inhibitor of the CD28-CD80/86-pathway, belatacept, allows calcineurininhibitor-free immunosuppression in kidney... 
ALLOGRAFT SURVIVAL | PHENOTYPE | MEMORY | TACROLIMUS | BLOCKADE | MULTIDISCIPLINARY SCIENCES | Abatacept - pharmacology | T-Lymphocyte Subsets - immunology | Isoantigens - administration & dosage | Kidney Failure, Chronic - immunology | T-Lymphocyte Subsets - cytology | Humans | Cells, Cultured | Immunophenotyping | Kidney Transplantation | Down-Regulation - drug effects | Immunologic Memory - drug effects | Abatacept - administration & dosage | CD28 Antigens - metabolism | Kidney Failure, Chronic - therapy | Allografts | Cell Differentiation - drug effects | T-Lymphocyte Subsets - drug effects | Cell Proliferation - drug effects | Immunosuppressive Agents - pharmacology | Immunosuppressive Agents - administration & dosage | Interferon-gamma - biosynthesis | Complications and side effects | Care and treatment | Immunosuppression | Chronic kidney failure | Physiological aspects | Genetic aspects | Belatacept | Dosage and administration | Research | T cells | End-stage renal disease | Nephrology | Transplants & implants | Anergy | Syngeneic grafts | Calcineurin | Immunoglobulin G | Effector cells | Stimulation | Transplantation | Lymphocytes T | CD28 antigen | Cell growth | Lymphocytes | Antigens | Immunological memory | Memory cells | Internal medicine | CD80 antigen | Patients | Medicine | Inhibitors | γ-Interferon | Kidney diseases | Kidney transplantation
Journal Article