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Journal Article
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 10/2014, Volume 592, Issue 20, pp. 4575 - 4589
Key points Oxidative stress is widely considered a major cause of muscle loss not only in disuse but also in most chronic diseases, triggering carbonylation of... 
TIBIALIS ANTERIOR | SKELETAL-MUSCLE | GAMMA COACTIVATOR 1-ALPHA | OXIDATIVE STRESS | PHYSIOLOGY | MITOCHONDRIAL BIOGENESIS | GENE-EXPRESSION | TRANSCRIPTIONAL COACTIVATOR | UBIQUITIN LIGASES | PROTEIN-SYNTHESIS | NEUROSCIENCES | ANTIOXIDANT CAPACITY | Up-Regulation | Dynamins - metabolism | Superoxide Dismutase - genetics | Oxidative Stress | SKP Cullin F-Box Protein Ligases - genetics | Mitochondria, Muscle - metabolism | Male | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | RNA, Messenger - metabolism | Autophagy | Tripartite Motif Proteins | Chromans - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Muscle Proteins - metabolism | Apoptosis Regulatory Proteins - genetics | NF-E2-Related Factor 2 - genetics | Muscular Atrophy - prevention & control | Muscle Fibers, Skeletal - physiology | Superoxide Dismutase - metabolism | Beclin-1 | Muscular Atrophy - metabolism | Catalase - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Ubiquitin-Protein Ligases - metabolism | Dynamins - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Antioxidants - pharmacology | Transcription Factors - genetics | Apoptosis Regulatory Proteins - metabolism | Catalase - metabolism | Muscle Proteins - genetics | Transcription Factors - metabolism | Antioxidants - therapeutic use | Animals | Chromans - therapeutic use | Hindlimb Suspension - adverse effects | NF-E2-Related Factor 2 - metabolism | Mice | Mitochondria, Muscle - drug effects | Superoxide Dismutase-1 | Ubiquitin-Protein Ligases - genetics | Muscle
Journal Article
Journal Article
Progress in Neurobiology, ISSN 0301-0082, 2006, Volume 79, Issue 2, pp. 95 - 111
The proteolytical processing of the amyloid precursor protein (APP) gives rise to β-amyloid peptides, which accumulate in brains of Alzheimer's disease (AD)... 
Post-translational modification | Alternative splicing | Transcription factors | Translation | Transgenic mice | Amyloid precursor protein | Protein–protein interaction | mRNA expression | Gliosis | Enzymatic activity | Proteases | Aging | Alzheimer's disease | Promoter analysis | Protein-protein interaction | ALPHA-SECRETASE | BETA-SECRETASE ACTIVITY | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DNA-BINDING | alternative splicing | transcription factors | proteases | post-translational modification | NEUROSCIENCES | TRANSGENIC TG2576 MICE | GENE PROMOTER | transgenic mice | amyloid precursor protein | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | translation | enzymatic activity | ACTIVATED-RECEPTOR-GAMMA | promoter analysis | protein-protein interaction | aging | gliosis | NF-KAPPA-B | Amyloid Precursor Protein Secretases - genetics | Protein Biosynthesis | Humans | NF-kappa B - metabolism | Receptors, Muscarinic - metabolism | Sp1 Transcription Factor - metabolism | Alzheimer Disease - enzymology | Aspartic Acid Endopeptidases - genetics | YY1 Transcription Factor - metabolism | PPAR gamma - metabolism | Gene Expression Regulation, Enzymologic | Amyloid Precursor Protein Secretases - metabolism | Animals | Aging - physiology | 5' Untranslated Regions | Aspartic Acid Endopeptidases - metabolism | Amyloid beta-Protein Precursor - metabolism | Transcription, Genetic | Alzheimer Disease - genetics | Messenger RNA | Peptides | Neurons | Choline | Amyloid beta-protein | Development and progression | Genetic aspects | DNA binding proteins
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 09/2007, Volume 12, Issue 9, pp. 854 - 869
Journal Article