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science & technology (230) 230
life sciences & biomedicine (224) 224
humans (162) 162
animals (125) 125
gamma-secretase (102) 102
alzheimer's disease (95) 95
amyloid precursor protein secretases - antagonists & inhibitors (73) 73
notch (70) 70
mice (67) 67
amyloid precursor protein secretases - metabolism (64) 64
neurosciences & neurology (62) 62
neurosciences (59) 59
gamma-secretase inhibitor (55) 55
oncology (54) 54
biochemistry & molecular biology (52) 52
gamma secretase (50) 50
cell biology (48) 48
pharmacology & pharmacy (44) 44
receptors, notch - metabolism (44) 44
female (42) 42
alzheimer’s disease (40) 40
biological and medical sciences (36) 36
medical sciences (35) 35
signal transduction (35) 35
amyloid precursor protein (34) 34
gamma secretase inhibitor (34) 34
amyloid beta-peptides - metabolism (32) 32
cancer (32) 32
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neurology (31) 31
proteins (30) 30
secretase (29) 29
enzyme inhibitors - pharmacology (28) 28
alzheimer disease - metabolism (27) 27
amyloid (24) 24
alzheimer disease - drug therapy (23) 23
amyloid beta-protein precursor - metabolism (23) 23
cell line, tumor (23) 23
research (23) 23
presenilin (22) 22
gamma-secretase inhibitors (21) 21
mutation (21) 21
signal transduction - drug effects (21) 21
amyloid beta-protein (20) 20
mice, transgenic (19) 19
notch signaling (19) 19
analysis (18) 18
receptors, notch - antagonists & inhibitors (18) 18
alzheimers disease (17) 17
apoptosis (17) 17
app (17) 17
dose-response relationship, drug (17) 17
middle aged (17) 17
amyloid precursor protein secretases (16) 16
breast cancer (16) 16
membrane proteins - metabolism (16) 16
receptors, notch - genetics (16) 16
stem cells (16) 16
tumors (16) 16
aged (15) 15
clinical neurology (15) 15
enzymes (15) 15
mice, inbred c57bl (15) 15
protein binding (15) 15
antineoplastic agents - therapeutic use (14) 14
apoptosis - drug effects (14) 14
brain - metabolism (14) 14
chemistry, medicinal (14) 14
disease models, animal (14) 14
gamma‐secretase (14) 14
life sciences (14) 14
review (14) 14
amyloid beta (13) 13
biomedicine (13) 13
care and treatment (13) 13
cell proliferation - drug effects (13) 13
chemistry (13) 13
health aspects (13) 13
mental disorders (13) 13
pharmacology. drug treatments (13) 13
physical sciences (13) 13
alzheimer disease - genetics (12) 12
peptides (12) 12
physiological aspects (12) 12
protease inhibitors - pharmacology (12) 12
psychology. psychoanalysis. psychiatry (12) 12
receptor, notch1 - metabolism (12) 12
signal transduction - physiology (12) 12
adult (11) 11
alzheimer disease - enzymology (11) 11
amyloid precursor protein secretases - genetics (11) 11
biochemistry, general (11) 11
cell line (11) 11
cell proliferation (11) 11
clinical trials (11) 11
development and progression (11) 11
gamma secretase inhibitors (11) 11
genetic aspects (11) 11
kinases (11) 11
molecular biology (11) 11
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