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Nature Communications, ISSN 2041-1723, 01/2017, Volume 8, Issue 1, pp. 14128 - 14128
Apoptosis is a genetically regulated cell suicide programme mediated by activation of the effector caspases 3, 6 and 7. If apoptotic cells are not scavenged,... 
GSDMD | MEMBRANE ATTACK | GASDERMIN D | NECROSIS | GENE | MECHANISM | MULTIDISCIPLINARY SCIENCES | NLRP3 INFLAMMASOME ACTIVATION | GENOME-WIDE | PORE FORMATION | PYROPTOSIS
Journal Article
Immunopharmacology and Immunotoxicology, ISSN 0892-3973, 09/2019, Volume 41, Issue 5, pp. 538 - 548
Background: The pharmacological application of kaempferol, a natural flavonol present in different plant species, has been demonstrated to have extensive... 
pyroptosis | Splenic lymphocytes | kaempferol | gasdermin D | inflammation
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2018, Volume 24, Issue 23, pp. 6066 - 6077
Purpose: The induced death signals following oncogene inhibition underlie clinical efficacy of molecular targeted therapies against human cancer, and defects... 
METHYLATION | NECROSIS | ONCOLOGY | PHOSPHORYLATION | MITOCHONDRIAL | DOWNSTREAM | DOMAIN-LIKE PROTEIN | MIXED LINEAGE KINASE | GASDERMIN-D | IDENTIFICATION | DFNA5
Journal Article
Biomaterials, ISSN 0142-9612, 01/2020, Volume 227, p. 119570
Excessive release of interleukin-1β (IL-1β) is well-known to provoke cascades of inflammatory responses thus contributing to the pathogenesis of... 
Gasdermin D | Alcohol-induced steatohepatitis | Galactose | Interleukin-1β | Interleukin-1 receptor antagonist | Apolipoprotein A-I
Journal Article
Nature Reviews Immunology, ISSN 1474-1733, 03/2017, Volume 17, Issue 3, pp. 151 - 164
Journal Article
Journal of Immunology, ISSN 0022-1767, 2019, Volume 202, Issue 7, pp. 1911 - 1912
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 12/2016, Volume 41, Issue 12, pp. 1012 - 1021
Journal Article
Journal of Hepatology, ISSN 0168-8278, 04/2018, Volume 68, Issue 4, pp. 643 - 645
Journal Article
Journal Article
EMBO JOURNAL, ISSN 0261-4189, 05/2019, Volume 38, Issue 10
Pyroptosis is a form of lytic inflammatory cell death driven by inflammatory caspase-1, caspase-4, caspase-5 and caspase-11. These caspases cleave and activate... 
GSDMD | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | apoptosis | pannexin-1 | gasdermin | RELEASE | CLEAVAGE | CELL BIOLOGY | pyroptosis | GASDERMIN D | PORE | NLRP3 | 1 CHANNELS | CASPASE-11 | INHIBITOR
Journal Article
Journal Article