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Cell Stem Cell, ISSN 1934-5909, 2009, Volume 5, Issue 4, pp. 420 - 433
To examine transcription factor (TF) network(s), we created mouse ESC lines, in each of which 1 of 50 TFs tagged with a FLAG moiety is inserted into a... 
STEMCELL | SIGNALING PATHWAYS | DEVELOPMENTAL REGULATORS | CHROMATIN | EMBRYONIC STEM-CELLS | MOUSE EMBRYOS | GENOME-WIDE | SELF-RENEWAL | PLURIPOTENCY | DIFFERENTIATION | EXPRESSION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | GATA3 Transcription Factor - genetics | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Immunoprecipitation | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | GATA3 Transcription Factor - physiology | Gene Regulatory Networks - physiology | SOX9 Transcription Factor - physiology | Cell Differentiation - genetics | Basic Helix-Loop-Helix Transcription Factors - metabolism | Chromatin Immunoprecipitation | Kruppel-Like Transcription Factors - metabolism | Cell Differentiation - physiology | GATA3 Transcription Factor - metabolism | Proto-Oncogene Proteins - metabolism | SOX9 Transcription Factor - metabolism | Cell Line | Basic Helix-Loop-Helix Transcription Factors - physiology | Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Gene Regulatory Networks - genetics | Kruppel-Like Transcription Factors - physiology | Proto-Oncogene Proteins - genetics | Transcription Factors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Animals | Proto-Oncogene Proteins - physiology | Mice | CDX2 Transcription Factor | Homeodomain Proteins - physiology | Kruppel-Like Transcription Factors - genetics | SOX9 Transcription Factor - genetics
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 02/2013, Volume 190, Issue 3, pp. 1056 - 1065
In refractory asthma, neutrophils, rather than eosinophils, often predominate in the airways. Neutrophilic airway inflammation appears to be resistant to... 
BET | OVEREXPRESSION | HUMAN NEUTROPHILS | IL-17 | MICE | MECHANISMS | IMMUNOLOGY | INTERLEUKIN-6 | HYPERRESPONSIVENESS | EXPRESSION | TH17 CELLS | GATA3 Transcription Factor - genetics | Ovalbumin - immunology | GATA3 Transcription Factor - physiology | Interleukin-17 - physiology | Lymphopoiesis - genetics | Recombinant Fusion Proteins - physiology | GATA3 Transcription Factor - biosynthesis | Receptors, Interleukin-6 - antagonists & inhibitors | Th2 Cells - immunology | Receptors, Interleukin-8B - antagonists & inhibitors | Immunoglobulin E - blood | Ovalbumin - toxicity | Immunoglobulin E - immunology | Lymphokines - genetics | Th17 Cells - metabolism | Asthma - immunology | Female | Lymphokines - biosynthesis | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Disease Models, Animal | Recombinant Fusion Proteins - biosynthesis | Chemokines - biosynthesis | Lung - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Mice, Transgenic | Chemokines - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - physiology | Th2 Cells - metabolism | Asthma - genetics | Phenotype | Animals | Interleukin-17 - antagonists & inhibitors | Nuclear Receptor Subfamily 1, Group F, Member 3 - biosynthesis | Recombinant Fusion Proteins - genetics | Th17 Cells - immunology | Mice | Lung - immunology
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 2007, Volume 27, Issue 1, pp. 89 - 99
Journal Article
Development (Cambridge), ISSN 0950-1991, 03/2013, Volume 140, Issue 6, pp. 1207 - 1219
Hematopoiesis is a classic system with which to study developmental potentials and to investigate gene regulatory networks that control choices among alternate... 
Mouse | Sfpi1 | Myb | Gene regulatory network | Quantitative gene expression analysis | Lineage decision | T-cell development | TRANSCRIPTION FACTORS | PHOSPHORYLATION | DEVELOPMENTAL BIOLOGY | SPECIFICATION | HEMATOPOIETIC PROGENITORS | LINEAGE COMMITMENT | IN-VITRO | BETA-SELECTION | TARGET GENE | EXPRESSION | GATA3 Transcription Factor - genetics | T-Lymphocytes - physiology | Embryo, Mammalian | Receptors, Notch - metabolism | Thymocytes - metabolism | GATA3 Transcription Factor - physiology | Proto-Oncogene Proteins c-myb - genetics | Receptors, Notch - genetics | Trans-Activators - physiology | Cell Differentiation - genetics | Proto-Oncogene Proteins c-myb - physiology | T-Lymphocytes - metabolism | Trans-Activators - genetics | Cell Differentiation - physiology | GATA3 Transcription Factor - metabolism | Cell Lineage - genetics | Gene Expression Regulation, Developmental - physiology | Genes, Switch - physiology | Thymocytes - physiology | Proto-Oncogene Proteins - metabolism | Myeloid Progenitor Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Receptors, Notch - physiology | Hematopoiesis - genetics | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | Proto-Oncogene Proteins c-myb - metabolism | Animals | Myeloid Progenitor Cells - physiology | Models, Biological | Proto-Oncogene Proteins - physiology | Trans-Activators - metabolism | Mice | Development and Stem Cells
Journal Article
Journal Article