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ONCOLOGIST, ISSN 1083-7159, 05/2014, Volume 19, Issue 5, pp. 550 - 561
We provide an overview of imaging, histopathology, genetics, and multidisciplinary treatment of giant cell tumor of bone (GCTB), an intermediate, locally... 
RANK ligand | PATHOLOGICAL FRACTURE | MEGAVOLTAGE RADIATION-THERAPY | SERIAL ARTERIAL EMBOLIZATION | FACTOR-KAPPA-B | GCTB | Review | Denosumab | Radiotherapy | MUSCULOSKELETAL TUMORS | CONSERVATIVE SURGERY | LONG BONES | Giant cell tumor of bone | Curettage | Histopathology | LOCAL RECURRENCE | ONCOLOGY | RECEPTOR ACTIVATOR | TERM-FOLLOW-UP
Journal Article
Molecular Therapy - Nucleic Acids, ISSN 2162-2531, 12/2018, Volume 13, pp. 493 - 502
Giant cell tumors of bone (GCTBs) exhibit high recurrence and aggressive bone lytic behavior; but, the mechanism of GCTB progression is largely unknown. In... 
recurrence | miR-125a | β-catenin signaling | GCTB | IL-17A | MEDICINE, RESEARCH & EXPERIMENTAL | STROMAL CELLS | MICRORNAS
Journal Article
Archives of Bone and Joint Surgery, ISSN 2345-4644, 2016, Volume 4, Issue 1, pp. 2 - 9
Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be... 
Giant cell tumor of bone | GCT | GCTB | Review of giant cell tumor | Giant Cell Tumor of Bone | Current Concept Review
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2017, Volume 76, pp. 118 - 124
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 07/2018, Volume 103, pp. 1092 - 1100
In this article, we explored the nature of the anti-cancer effects of norcantharidin (NCTD) in Giant cell tumor of bone (GCTB) and to elucidate the... 
miR-30a/Metadherin/AKT axis | Proliferation | Metastasis | Giant cell tumor of bone (GCTB) | Norcantharidin | ASTROCYTE ELEVATED GENE-1 | MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | RESVERATROL | BREAST-CANCER CELL | HEPATOCELLULAR-CARCINOMA | PATHWAY | IN-VIVO | PROSTATE-CANCER | GROWTH | PHARMACOLOGY & PHARMACY | EXPRESSION | Synthesis | Glycogen | Analysis | Cancer
Journal Article
Cancer Science, ISSN 1347-9032, 06/2014, Volume 105, Issue 6, pp. 744 - 748
Journal Article
International Journal of Clinical and Experimental Medicine, ISSN 1940-5901, 03/2016, Volume 9, Issue 3, pp. 6046 - 6053
Giant cell tumor of bone (GCTB) is an aggressive skeletal neoplasm and exhibits malignant bone lytic behavior. However, little is known regarding the molecular... 
MiR-124 | MiRNAs | RANKL | GCTB | GCTSCs | MEDICINE, RESEARCH & EXPERIMENTAL | miRNAs | DOWN-REGULATION | PROLIFERATION | MICRORNAS | CANCER | miR-124 | OSTEOCLASTOGENESIS | INVASION | EXPRESSION
Journal Article
The Archives of Bone & Joint Surgery, ISSN 2345-4644, 01/2016, Volume 4, Issue 1, pp. 2 - 9
Giant Cell tumors (GCT) are benign tumors with potential for aggressive behavior and capacity to metastasize. Although rarely lethal, benign bone tumors may be... 
Giant Cell Tumor of Bone | GCT | GCTB | Review of giant cell tumor
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 07/2015, Volume 36, Issue 5, pp. 1961 - 1970
Background/Aims: This aim of the present study was to identify specific markers determining the recurrence of the giant cell tumor of bone (GCTB). Methods:... 
Original Paper | Campanacci grade | GCTB | CD147 | Surgery | PHYSIOLOGY | MOLECULE | INCREASES | RISK | PROLIFERATION | CURETTAGE | CANCER | CELL BIOLOGY | INVASION | GENE-EXPRESSION | PROGRESSION | Giant Cell Tumor of Bone - surgery | Humans | Middle Aged | Neoplasm Recurrence, Local | Male | Bone Neoplasms - surgery | Bone Neoplasms - pathology | Young Adult | Disease-Free Survival | Giant Cell Tumor of Bone - pathology | Adolescent | Adult | Female | Aged
Journal Article
Translational Research, ISSN 1931-5244, 2014, Volume 164, Issue 2, pp. 139 - 148
Journal Article
Future Oncology, ISSN 1479-6694, 07/2015, Volume 11, Issue 13, pp. 1881 - 1894
Giant cell tumor of bone is typically composed of neoplastic stromal cells and non-neoplastic osteoclastic giant cells. RANK-expressing osteoclastic giant... 
giant cell tumor of bone | RANKL | osteoclastic giant cells | stromal cells | osteoclast activity | bone turnover | RANK | GCTB | denosumab | BISPHOSPHONATE | METASTASES | PHASE-II | BREAST-CANCER | ZOLEDRONIC ACID | ONCOLOGY | RECEPTOR ACTIVATOR | RECURRENCE | PAGETS-DISEASE | OF-THE-LITERATURE | POSTMENOPAUSAL WOMEN
Journal Article
Sugar Tech, ISSN 0972-1525, 6/2017, Volume 19, Issue 3, pp. 248 - 257
Ethanol is an alternative source of renewable fuel, but increasing production of vinasse as a by-product requires proper management. Combining concentrated... 
Life Sciences | Urea | Nitrogen use efficiency | Agriculture | GCTB | Sugarcane trash | AGRONOMY | CROPS | SOIL | TRASH | Phosphates | Evaluation | Ammonia | Phosphoric acid | Usage | Nitrogen fertilizers | Urea as fertilizer | Sugarcane
Journal Article
The Journal of Pathology, ISSN 0022-3417, 05/2008, Volume 215, Issue 1, pp. 56 - 66
Hypoxia is an important regulator of bone biology and stimulates osteoclast differentiation from monocytic precursors. Hypoxia‐inducible factor (HIF) is a key... 
hypoxia | differentiation | giant cell tumour of bone (GCTB) | VEGF | hypoxia‐inducible factor (HIF) | siRNA | osteoblast | osteoclast | Osteoblast | Hypoxia | Osteoclast | Differentiation | Giant cell tumour of bone (GCTB) | Hypoxia-inducible factor (HIF) | RESORPTION | COLONY-STIMULATING FACTOR | OSTEOBLAST-LIKE CELLS | PATHOLOGY | SOFT-TISSUE | BREAST-CANCER | IN-VITRO | hypoxia-inducible factor (HIF) | HIF-1 ACTIVITY | ONCOLOGY | SIGNALING PATHWAY | LOW-OXYGEN-TENSION | ENDOTHELIAL GROWTH-FACTOR | Hypoxia-Inducible Factor 1, alpha Subunit - analysis | Immunohistochemistry | Blotting, Western - methods | Osteoclasts - pathology | Basic Helix-Loop-Helix Transcription Factors - genetics | Paracrine Communication | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Humans | Cells, Cultured | Gene Expression Regulation, Neoplastic | Basic Helix-Loop-Helix Transcription Factors - analysis | Vascular Endothelial Growth Factor A - metabolism | Hepatocyte Growth Factor - pharmacology | Cell Hypoxia | Basic Helix-Loop-Helix Transcription Factors - metabolism | Giant Cell Tumor of Bone - metabolism | Giant Cell Tumor of Bone - pathology | RNA Interference | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Monocytes - pathology | Cell Line, Tumor | Macrophage Colony-Stimulating Factor - pharmacology | Cell Differentiation | RNA, Small Interfering - administration & dosage
Journal Article