X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
gdc-0449 (5) 5
gdc‐0449 (5) 5
index medicus (4) 4
cancer (3) 3
female (3) 3
humans (3) 3
pharmacology & pharmacy (3) 3
anilides - administration & dosage (2) 2
animals (2) 2
embryonic development (2) 2
hedgehog proteins - antagonists & inhibitors (2) 2
hedgehog proteins - metabolism (2) 2
male (2) 2
middle aged (2) 2
pyridines - administration & dosage (2) 2
signal transduction (2) 2
signaling pathway (2) 2
toxicology (2) 2
vismodegib (2) 2
a-ring analogs (1) 1
aberration (1) 1
absolute bioavailability (1) 1
accelerator mass-spectrometry (1) 1
activation (1) 1
adult (1) 1
analysis (1) 1
anilides - pharmacokinetics (1) 1
anilides - therapeutic use (1) 1
anilides - toxicity (1) 1
anticancer (1) 1
antineoplastic agents - administration & dosage (1) 1
antineoplastic agents - chemistry (1) 1
antineoplastic agents - pharmacokinetics (1) 1
antineoplastic agents - therapeutic use (1) 1
apoptosis (1) 1
article (1) 1
basal cell carcinoma (1) 1
basal-cell carcinoma (1) 1
basal‐cell carcinoma (1) 1
biochemistry & molecular biology (1) 1
biological availability (1) 1
biological evaluation (1) 1
biopsy (1) 1
biphasic (1) 1
blood proteins (1) 1
blood proteins - metabolism (1) 1
carcinoma (1) 1
carcinoma, basal cell - diagnosis (1) 1
carcinoma, basal cell - drug therapy (1) 1
carcinoma, basal cell - metabolism (1) 1
care and treatment (1) 1
caspase (1) 1
cell biology (1) 1
cell lines (1) 1
cell proliferation (1) 1
cell-growth (1) 1
chemistry, medicinal (1) 1
chromatography, liquid (1) 1
clearance (1) 1
cyclopamine (1) 1
cyclopamine analogs (1) 1
database (1) 1
development and progression (1) 1
diagnosis, differential (1) 1
dose responses (1) 1
dose-response relationship, drug (1) 1
drug administration schedule (1) 1
embryolethality (1) 1
embryonic development - drug effects (1) 1
erivedge (1) 1
expression (1) 1
fetus - drug effects (1) 1
fetus - embryology (1) 1
fetus - pathology (1) 1
fetuses (1) 1
follow-up studies (1) 1
gant-61 (1) 1
gant‐61 (1) 1
gdc 0449 (1) 1
genetics & heredity (1) 1
gli (1) 1
growth (1) 1
half-life (1) 1
head and neck neoplasms - diagnosis (1) 1
head and neck neoplasms - drug therapy (1) 1
head and neck neoplasms - metabolism (1) 1
health aspects (1) 1
hedgehog (1) 1
hedgehog antagonist (1) 1
hedgehog inhibitor (1) 1
hedgehog pathway (1) 1
hedgehog protein (1) 1
hedgehog signaling pathway (1) 1
highly potent (1) 1
hormesis (1) 1
human plasma (1) 1
in-vitro (1) 1
inflammatory diseases (1) 1
inhibition (1) 1
inhibitor (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Dose-Response, ISSN 1559-3258, 1/2010, Volume 8, Issue 1, pp. 80 - 82
Enhanced drug (GDC 0449) resistance in a mouse model for human medulloblastoma is shown in the present paper to act via an hormetic response. This has... 
Biphasic | GDC 0449 | Hormesis | Tumor relapse | Medulloblastoma | Hedgehog pathway | DOSE RESPONSES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DATABASE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.