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Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2013, Volume 123, Issue 11, pp. 4627 - 4640
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 06/2011, Volume 29, Issue 18, pp. 2499 - 2506
Journal Article
Cancer Cell, ISSN 1535-6108, 08/2012, Volume 22, Issue 2, pp. 180 - 193
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2013, Volume 210, Issue 12, pp. 2641 - 2659
Journal Article
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 28789
ASXL1 mutations are found in a spectrum of myeloid malignancies with poor prognosis. Recently, we reported that Asxl1(+/-) mice develop myelodysplastic... 
TRANSFORMATION | FREQUENT | IMPACT | GENE | POOR-PROGNOSIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | STEM-CELL | MUTATIONS | MYELODYSPLASTIC SYNDROMES | DISTINCT STAGES
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2733 - 18
ASXL1 mutations occur frequently in myeloid neoplasms and are associated with poor prognosis. However, the mechanisms by which mutant ASXL1 induces... 
TRANSFORMATION | CLONAL HEMATOPOIESIS | MULTIDISCIPLINARY SCIENCES | EXPANSION | LEADS | FREQUENT MUTATION | SELF-RENEWAL | LEUKEMIA | EXPRESSION | MYELODYSPLASTIC SYNDROMES | TUMOR-SUPPRESSOR BAP1 | Whole-Body Irradiation | Homeodomain Proteins - metabolism | Humans | Leukemia, Myeloid - genetics | Interferon Regulatory Factors - metabolism | Male | Carcinogenesis - metabolism | Leukemia, Myeloid - pathology | Ubiquitination | Bone Marrow - metabolism | Tumor Suppressor Proteins - genetics | Bone Marrow Transplantation | HEK293 Cells | Ubiquitin Thiolesterase - metabolism | Female | RUNX1 Translocation Partner 1 Protein - genetics | Leukemia, Myeloid - mortality | RUNX1 Translocation Partner 1 Protein - metabolism | Repressor Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Core Binding Factor Alpha 2 Subunit - metabolism | Signal Transduction | Mice, Inbred C57BL | Carcinogenesis - genetics | Interferon Regulatory Factors - genetics | Repressor Proteins - genetics | Gene Expression Regulation, Leukemic | Ubiquitin Thiolesterase - genetics | Gene Editing | Homeodomain Proteins - genetics | Carcinogenesis - pathology | Animals | Leukemia, Myeloid - metabolism | Bone Marrow - pathology | CRISPR-Cas Systems | Survival Analysis | Mice | HeLa Cells | Mutation | Core Binding Factor Alpha 2 Subunit - genetics | Myeloid leukemia | Leukemia | Runx1 protein | Gene expression | Progenitor cells | Neoplasms | Cells (biology) | Stem cells | Tumor suppressor genes | HOXA gene | Catalysis | Tumors
Journal Article