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Nature Structural and Molecular Biology, ISSN 1545-9993, 02/2013, Volume 20, Issue 2, pp. 144 - 149
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7489, pp. 456 - 462
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2014, Volume 111, Issue 21, pp. 7741 - 7746
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2017, Volume 198, Issue 5, pp. 2133 - 2146
Journal Article
Gastroenterology, ISSN 0016-5085, 2013, Volume 145, Issue 6, pp. 1347 - 1357
Journal Article
Autophagy, ISSN 1554-8627, 04/2015, Volume 11, Issue 4, pp. 585 - 594
Genetic variations in the autophagic pathway influence genetic predispositions to Crohn disease. Autophagy, the major lysosomal pathway for degrading and... 
XBP1, X-box binding protein 1 | MTOR, mechanistic target of rapamycin | autophagy | DCs, dendritic cells | UC, ulcerative colitis | bacterial clearance | NFKB, nuclear factor of kappa light polypeptide gene enhancer in B-cells | SNP, single-nucleotide polymorphism | NOD2 | T300A, threonine-to-alanine substitution at amino acid position 300 | MDP, muramyl dipeptide | ULK1, unc-51 like autophagy-activating kinase 1 | endoplasmic reticulum stress | RIPK2, receptor-interacting serine-threonine kinase 2 | Crohn disease | ATG16L1 | ATG16L1, autophagy-related 16-like 1 (S. cerevisiae) | IBD, inflammatory bowel disease | TNF/TNF-α, tumor necrosis factor | NOD2, nucleotide-binding oligomerization domain containing 2 | ER, endoplasmic reticulum | GWAS, genome-wide association studies | BCL2, B-cell CLL/lymphoma 2 | Autophagy | Bacterial clearance | Endoplasmic reticulum stress | IMPAIRED AUTOPHAGY | REGULATES AUTOPHAGY | SELECTIVE AUTOPHAGY | INTESTINAL EPITHELIAL-CELLS | CELL BIOLOGY | AUTOPHAGY GENE ATG16L1 | INFLAMMATORY-BOWEL-DISEASE | RECYCLING ENDOSOMES | PROTEIN LIPIDATION | PANETH CELLS | GENOME-WIDE ASSOCIATION | Carrier Proteins - genetics | Crohn Disease - genetics | Autophagy-Related Proteins | Genetic Predisposition to Disease - genetics | Animals | Humans | Crohn Disease - metabolism | Polymorphism, Single Nucleotide - genetics | Autophagy - physiology | Autophagy - genetics | Endoplasmic Reticulum Stress - genetics
Journal Article