X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2655) 2655
Publication (279) 279
Newspaper Article (113) 113
Newsletter (96) 96
Book Review (26) 26
Book Chapter (19) 19
Magazine Article (8) 8
Trade Publication Article (4) 4
Conference Proceeding (3) 3
Data Set (3) 3
Dissertation (3) 3
Reference (2) 2
Book / eBook (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1647) 1647
humans (1625) 1625
parkinson's disease (1308) 1308
mutation (906) 906
parkinson disease - genetics (891) 891
genetic aspects (799) 799
neurosciences (771) 771
genes (725) 725
male (703) 703
animals (679) 679
female (671) 671
gene expression (650) 650
gene (578) 578
leucine-rich repeat serine-threonine protein kinase-2 (574) 574
protein-serine-threonine kinases - genetics (554) 554
proteins (541) 541
research (536) 536
middle aged (528) 528
clinical neurology (527) 527
aged (494) 494
lrrk2 (482) 482
parkinsons disease (463) 463
alpha-synuclein (457) 457
neurodegenerative diseases (454) 454
genetics (452) 452
mutations (412) 412
movement disorders (384) 384
analysis (369) 369
neurodegeneration (359) 359
parkinsons-disease (352) 352
kinases (350) 350
neurology (348) 348
research article (348) 348
nervous system diseases (345) 345
medicine (344) 344
adult (343) 343
mice (317) 317
risk factors (317) 317
gene mutations (315) 315
multidisciplinary sciences (315) 315
neurons (314) 314
genetics & heredity (304) 304
biochemistry & molecular biology (298) 298
genetic predisposition to disease (298) 298
genetic research (268) 268
genomes (267) 267
disease (258) 258
article (254) 254
cell biology (249) 249
parkinson disease - metabolism (247) 247
aged, 80 and over (244) 244
science (244) 244
health aspects (241) 241
genotype (240) 240
studies (238) 238
phosphorylation (236) 236
genomics (234) 234
medical research (232) 232
brain (226) 226
parkinson disease (224) 224
physiological aspects (224) 224
dopamine (216) 216
mutation - genetics (213) 213
protein-serine-threonine kinases - metabolism (212) 212
oxidative stress (209) 209
biology (206) 206
autosomal-dominant parkinsonism (203) 203
expression (200) 200
parkinson disease - pathology (195) 195
pathology (189) 189
development and progression (188) 188
nervous system (188) 188
parkinson’s disease (188) 188
neuroscience (187) 187
pathogenesis (187) 187
review (183) 183
association (181) 181
medicine, experimental (178) 178
gene frequency (177) 177
protein (172) 172
lrrk2 protein (171) 171
alzheimers-disease (169) 169
phenotype (168) 168
risk (168) 168
apoptosis (167) 167
stem cells (165) 165
dementia (164) 164
mitochondria (163) 163
autophagy (159) 159
case-control studies (157) 157
disease models, animal (153) 153
alpha-synuclein - genetics (152) 152
dna mutational analysis (151) 151
identification (151) 151
alzheimer's disease (147) 147
gene-expression (145) 145
genome-wide association (145) 145
cancer (143) 143
rodents (143) 143
signal transduction (140) 140
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2880) 2880
German (4) 4
Russian (3) 3
Chinese (2) 2
French (2) 2
Spanish (2) 2
Hungarian (1) 1
Japanese (1) 1
Korean (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23207
Leucine rich repeat kinase 2 (LRRK2) is a Parkinson's disease (PD) gene that encodes a large multidomain protein including both a GTPase and a kinase domain.... 
DISEASE-ASSOCIATED MUTATIONS | LEUCINE-RICH-REPEAT-KINASE-2 | PROTEIN | INHIBITION | GENE | DIMER | MULTIDISCIPLINARY SCIENCES | PHOSPHORYLATES | DOMINANT PARKINSONISM | ROC DOMAIN | Recombinant Proteins - metabolism | Phosphorylation | Immunoprecipitation | Humans | Guanosine Triphosphate - analogs & derivatives | Protein-Serine-Threonine Kinases - genetics | Immunoblotting | Guanosine Triphosphate - metabolism | Binding Sites - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | 14-3-3 Proteins - metabolism | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | GTP Phosphohydrolases - metabolism | GTP Phosphohydrolases - genetics | HEK293 Cells | Protein Binding | Guanosine Diphosphate - metabolism | Mutation | Protein-Serine-Threonine Kinases - metabolism | 14-3-3 Proteins - genetics | Amino Acid Substitution | Proteins | Purines | Cellular signal transduction | Nucleotides | G proteins | Phosphotransferases | Protein binding | Molecular machines | GTP | Neurosciences | Parkinson's disease | Peptides | Laboratories | Neurobiology | Parkinsons disease | Switches | Labelling | Leucine | Kinases | Guanine nucleotide-binding protein | Guanine | Lysates | Neurodegeneration | Cascades | LRRK2 protein | Movement disorders | Recombinant | Neurodegenerative diseases | Neutrophils | Gene expression | Mutants | Transduction | Gene therapy | Binding sites | Guanosinetriphosphatase
Journal Article
Nature Neuroscience, ISSN 1097-6256, 04/2013, Volume 16, Issue 4, pp. 394 - 406
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 11/2009, Volume 111, Issue 3, pp. 703 - 715
Mutations in the gene encoding leucine‐rich repeat kinase 2 (LRRK2) are the most common cause of autosomal‐dominant familial and late‐onset sporadic... 
dimerization | leucine‐rich repeat kinase 1 | kinase inhibition | leucine‐rich repeat kinase 2 | Parkinson’s disease | death‐associated protein kinase 1 | Leucine-rich repeat kinase 1 | Death-associated protein kinase 1 | Leucine-rich repeat kinase 2 | Parkinson's disease | Kinase inhibition | Dimerization | leucine-rich repeat kinase 2 | DISEASE-ASSOCIATED MUTATIONS | GENE LRRK2 | ACTIVATION | DOMAIN | leucine-rich repeat kinase 1 | AUTOSOMAL-DOMINANT PARKINSONISM | LEUCINE-RICH-REPEAT-KINASE-2 LRRK2 | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEURONAL TOXICITY | GTP-BINDING | NEUROSCIENCES | death-associated protein kinase 1 | Lipids - genetics | Calcium-Calmodulin-Dependent Protein Kinases - genetics | Apoptosis Regulatory Proteins - chemistry | Humans | Protein-Serine-Threonine Kinases - genetics | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Mutation - genetics | Apoptosis Regulatory Proteins - metabolism | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Calcium-Calmodulin-Dependent Protein Kinases - chemistry | Two-Hybrid System Techniques | Transfection - methods | Protein Multimerization - genetics | Apoptosis Regulatory Proteins - genetics | Protein Conformation | Protein-Serine-Threonine Kinases - chemistry | Death-Associated Protein Kinases | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Cell Line, Transformed | Protein-Serine-Threonine Kinases - metabolism | Proteins | Protein kinases | Neurology | Biochemistry | Mutation | Kinases | Parkinsons disease
Journal Article
Journal Article
Journal Article