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Journal Article
EMBO journal, ISSN 0261-4189, 2012, Volume 31, Issue 14, pp. 3079 - 3091
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2012, Volume 109, Issue 15, pp. 5832 - 5837
Human Epidermal Growth Factor Receptor 2-positive (HER2⁺) breast cancer (BC) is a highly aggressive disease commonly treated with chemotherapy and anti-HER2... 
Chemotherapy | Health outcomes | Disease models | Stem cells | Breast cancer | Signatures | Cells | Cell transplantation | Tumors | Cancer | Prognostic signature | breast cancer | Cancer stem cells | HER2 | Mouse models | mouse models | STEM-CELLS | SUBTYPES | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | HER2(+) breast cancer | cancer stem cells | IDENTIFICATION | TUMORIGENESIS | prognostic signature | P53 | Prognosis | Neoplastic Stem Cells - drug effects | CD24 Antigen - metabolism | Humans | Receptor, ErbB-2 - metabolism | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Intercellular Signaling Peptides and Proteins - metabolism | Neoplastic Stem Cells - metabolism | Serrate-Jagged Proteins | Antibodies, Monoclonal, Humanized - pharmacology | Neoplastic Stem Cells - pathology | Estrogen Receptor alpha - metabolism | Female | Neoadjuvant Therapy | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Genes, Neoplasm - genetics | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Antibodies, Monoclonal, Humanized - therapeutic use | Treatment Outcome | Breast Neoplasms - drug therapy | Cell Division - drug effects | Animals | Breast Neoplasms - genetics | Signal Transduction - drug effects | Cell Differentiation - drug effects | Mice | Trastuzumab | Index Medicus | trastuzumab | Immune response | Epidermal growth factor receptors | Risk groups | ErbB-2 protein | Survival | Risk factors | Lymph | Biological Sciences | HER2+ breast cancer
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2010, Volume 107, Issue 22, pp. 10208 - 10213
PIK3CA mutations are reported to be present in approximately 25% of breast cancer (BC), particularly the estrogen receptor—positive (ER+) and... 
Datasets | Health outcomes | Prognosis | Cell lines | Breast cancer | Signatures | Gene expression | Genetic mutation | Tumors | Cancer | Gene expression profiling | PI3 kinase | MOLECULAR SUBTYPES | TYROSINE PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PTEN | 3-KINASE MUTATIONS | AKT | EXPRESSION PROFILES | TUMORS | INSULIN-RECEPTOR | PATHWAY | POOR-PROGNOSIS | gene expression profiling | Neoplasms, Hormone-Dependent - metabolism | Receptors, Estrogen - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Multiprotein Complexes | Receptor, ErbB-2 - metabolism | DNA Primers - genetics | Gene Expression Profiling | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Mechanistic Target of Rapamycin Complex 1 | Neoplasms, Hormone-Dependent - genetics | Proteins | Antineoplastic Agents, Hormonal - therapeutic use | Base Sequence | Female | Sirolimus - therapeutic use | Signal Transduction | Breast Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Antibiotics, Antineoplastic - therapeutic use | Tamoxifen - therapeutic use | Cell Line, Tumor | TOR Serine-Threonine Kinases | Mutation | Neoplasms, Hormone-Dependent - drug therapy | Receptors | Analysis | Estrogen | Genetic aspects | Research | Properties | Tamoxifen | Protein kinases | Health aspects | Genotype & phenotype | Oncology | Kinases | Clinical outcomes | Index Medicus | TOR protein | Transformation | Exons | Estrogens | AKT protein | Data processing | 1-Phosphatidylinositol 3-kinase | Signal transduction | Biological Sciences
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2010, Volume 16, Issue 5, pp. 586 - 591
Journal Article