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Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2010, Volume 107, Issue 22, pp. 10208 - 10213
...—associated gene signature (PIK3CA-GS) derived from exon 20 (kinase domain) mutations was able to predict PIK3CA mutation status in two independent datasets, strongly... 
Datasets | Health outcomes | Prognosis | Cell lines | Breast cancer | Signatures | Gene expression | Genetic mutation | Tumors | Cancer | Gene expression profiling | PI3 kinase | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms, Hormone-Dependent - metabolism | Receptors, Estrogen - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Multiprotein Complexes | Receptor, ErbB-2 - metabolism | DNA Primers - genetics | Gene Expression Profiling | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Mechanistic Target of Rapamycin Complex 1 | Neoplasms, Hormone-Dependent - genetics | Proteins | Antineoplastic Agents, Hormonal - therapeutic use | Base Sequence | Female | Sirolimus - therapeutic use | Signal Transduction | Breast Neoplasms - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Antibiotics, Antineoplastic - therapeutic use | Tamoxifen - therapeutic use | Cell Line, Tumor | TOR Serine-Threonine Kinases | Mutation | Neoplasms, Hormone-Dependent - drug therapy | Receptors | Analysis | Estrogen | Genetic aspects | Research | Properties | Tamoxifen | Protein kinases | Health aspects | Genotype & phenotype | Oncology | Kinases | Clinical outcomes | Index Medicus | TOR protein | Transformation | Exons | Estrogens | AKT protein | Data processing | 1-Phosphatidylinositol 3-kinase | Signal transduction | gene expression profiling | Biological Sciences
Journal Article
Journal Article
Nature genetics, ISSN 1546-1718, 09/2012, Volume 44, Issue 11, pp. 1243 - 1248
Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) and thereby potentially... 
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Gene mutations | RNA | Aicardi syndrome | Physiological aspects | Genetic aspects | Interferon | Adenosine deaminase | Research | Health aspects | Risk factors | Proteins | Medical research | Genetics | Mutation | Index Medicus
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 2007, Volume 132, Issue 2, pp. 628 - 632
Journal Article
by Joehanes, Roby and Just, Allan C and Marioni, Riccardo E and Pilling, Luke C and Reynolds, Lindsay M and Mandaviya, Pooja R and Guan, Weihua and Xu, Tao and Elks, Cathy E and Aslibekyan, Stella and Moreno-Macias, Hortensia and Smith, Jennifer A and Brody, Jennifer A and Dhingra, Radhika and Yousefi, Paul and Pankow, James S and Kunze, Sonja and Shah, Sonia H and McRae, Allan F and Lohman, Kurt and Sha, Jin and Absher, Devin M and Ferrucci, Luigi and Zhao, Wei and Demerath, Ellen W and Bressler, Jan and Grove, Megan L and Huan, Tianxiao and Liu, Chunyu and Mendelson, Michael M and Yao, Chen and Kiel, Douglas P and Peters, Annette and Wang-Sattler, Rui and Visscher, Peter M and Wray, Naomi R and Starr, John M and Ding, Jingzhong and Rodriguez, Carlos J and Wareham, Nicholas J and Irvin, Marguerite R and Zhi, Degui and Barrdahl, Myrto and Vineis, Paolo and Ambatipudi, Srikant and Uitterlinden, André G and Hofman, Albert and Schwartz, Joel and Colicino, Elena and Hou, Lifang and Vokonas, Pantel S and Hernandez, Dena G and Singleton, Andrew B and Bandinelli, Stefania and Turner, Stephen T and Ware, Erin B and Smith, Alicia K and Klengel, Torsten and Binder, Elisabeth B and Psaty, Bruce M and Taylor, Kent D and Gharib, Sina A and Swenson, Brenton R and Liang, Liming and DeMeo, Dawn L and O’Connor, George T and Herceg, Zdenko and Ressler, Kerry J and Conneely, Karen N and Sotoodehnia, Nona and Kardia, Sharon L. R and Melzer, David and Baccarelli, Andrea A and van Meurs, Joyce B. J and Romieu, Isabelle and Arnett, Donna K and Ong, Ken K and Liu, Yongmei and Waldenberger, Melanie and Deary, Ian J and Fornage, Myriam and Levy, Daniel and London, Stephanie J
Circulation. Cardiovascular genetics, ISSN 1942-3268, 10/2016, Volume 9, Issue 5, pp. 436 - 447
Journal Article
Gastroenterology (New York, N.Y. 1943), ISSN 0016-5085, 05/2013, Volume 144, Issue 5, pp. 1024 - 1030
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2017, Volume 114, Issue 30, pp. 8071 - 8076
... (tRNA-derived small RNAs, hereafter “tsRNAs”) is dysregulated in cancer. Specifically, we uncovered tsRNA signatures in chronic lymphocytic leukemia and lung cancer and demonstrated that the cluster (now called “ ” and “ ,” respectively... 
tRF | tDR | tRNA fragments | ncRNA | tsRNA | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell proliferation | Biotechnology | Chromatin | Ovarian carcinoma | Genes | Leukemia | Gene regulation | Lung cancer | Ovarian cancer | Molecules | Colon cancer | Transcription activation | Colon | Signatures | Chronic lymphatic leukemia | Cell survival | Transposons | tRNA | Breast cancer | Tumor cell lines | Lymphatic leukemia | Ribonucleic acid--RNA | Gene expression | Survival | Mutation | Cancer | Apoptosis | Index Medicus | Biological Sciences
Journal Article