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Fisheries Research, ISSN 0165-7836, 12/2019, Volume 220, p. 105350
Induced triploidy typically causes sterility in teleost fishes, and has therefore been proposed as a tool to manage genetic risks that farmed and... 
Genetic risk | Hatchery | Management | Salmon
Journal Article
The Lancet Psychiatry, ISSN 2215-0366, 07/2019, Volume 6, Issue 7, pp. 551 - 552
Journal Article
CLINICAL GENETICS, ISSN 0009-9163, 11/2017, Volume 92, Issue 5, pp. 566 - 566
Journal Article
JAMA NEUROLOGY, ISSN 2168-6149, 05/2015, Volume 72, Issue 5, pp. 511 - 519
IMPORTANCE Typical cognitive aging may be defined as age-associated changes in cognitive performance in individuals who remain free of dementia. Ideally, the... 
GLUCOSE-METABOLISM | GENETIC RISK | ALZHEIMERS-DISEASE | OLDER-ADULTS | NEURODEGENERATION | HYPOTHETICAL MODEL | DYNAMIC BIOMARKERS | COGNITIVE FUNCTION | CLINICAL NEUROLOGY | APOLIPOPROTEIN-E | DECLINE
Journal Article
NEUROLOGY, ISSN 0028-3878, 05/2014, Volume 82, Issue 20, pp. 1760 - 1767
Objective:To examine whether -amyloid (A) and APOE epsilon 4 status independently contribute or interact to influence longitudinal cognitive decline in... 
NORMAL OLDER-ADULTS | HUMAN CEREBRAL-CORTEX | GENETIC RISK | GENOTYPE | DEPOSITION | A-BETA | COGNITIVE IMPAIRMENT | ASSOCIATION | ONSET | CLINICAL NEUROLOGY | APOLIPOPROTEIN-E
Journal Article
Social Science and Medicine, ISSN 0277-9536, 08/2016, Volume 163, pp. 21 - 27
Rationale Women with a harmful mutation in the BReast CAncer (BRCA) gene are at significantly increased risk of developing hereditary breast and ovarian cancer... 
BRCA | Genetic risk | Hereditary breast and ovarian cancer | Communication
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 12/2010, Volume 30, Issue 50, pp. 17035 - 17040
Identifying high-risk populations is an important component of disease prevention strategies. One approach for identifying at-risk populations for Alzheimer's... 
BRAIN ACTIVITY | DEFAULT-MODE | DEMENTIA | MEMORY | GENETIC RISK | GENOTYPE | ALZHEIMERS-DISEASE | NETWORK FUNCTION | NEUROSCIENCES | APOLIPOPROTEIN-E | BETA
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2014, Volume 5
Genome-wide association studies implicate dysregulation of immune mechanisms in the pathogenesis of multiple sclerosis (MS). Particularly, polymorphisms in... 
PHASE | CYTOKINES | THERAPY | PROTEIN | COLONY-STIMULATING FACTOR | GENETIC RISK | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | INTERFERON-BETA
Journal Article
LANCET, ISSN 0140-6736, 04/2018, Volume 391, Issue 10130, pp. 1622 - 1636
Multiple sclerosis continues to be a challenging and disabling condition but there is now greater understanding of the underlying genetic and environmental... 
GENETIC RISK BURDEN | CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | CLINICALLY ISOLATED SYNDROME | PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY | DOUBLE-BLIND | PHARMACOLOGICAL MANAGEMENT | FOLLOW-UP | COGNITIVE IMPAIRMENT | RETROSPECTIVE ANALYSIS | MAGNIMS CONSENSUS GUIDELINES
Journal Article
Neuroscience Letters, ISSN 0304-3940, 07/2019, Volume 706, pp. 140 - 145
Parkinson’s disease is the second most common neurodegenerative disease. Lifestyle, environmental effects and several genetic factors have been proposed to... 
MAPT | LRRK2 | Parkinson’s disease | Genetic risk factors | PARK10 | SNCA
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 01/2017, Volume 37, Issue 3, pp. 637 - 647
Neuroinflammation is an important contributor to Alzheimer's disease (AD) pathogenesis, as underscored by the recent identification of immune-related genetic... 
MICROGLIAL RESPONSE | ACTIVATION | SUSTAINS | MACROPHAGES | IMPAIRS | PATHOLOGY | PLAQUES | NEUROSCIENCES | genetic risk factor | myeloid cell | DEMYELINATION | inflammation | neuroinflammation | microglia | TRANSGENIC MICE | MYELOID CELLS-2
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2018, Volume 24, Issue 24, pp. 6265 - 6276
Journal Article
ISSN 0007-1145, 2016
Genetic risk prediction of chronic conditions including obesity, diabetes and cardiovascular disease currently has limited predictive power but its potential... 
behaviour change | systematic review | cardiometabolic | genetic risk
Journal Article
Lipids, ISSN 0024-4201, 10/2019, Volume 54, Issue 10, pp. 641 - 650
Maternal lipid profiles are associated with risk for preterm birth (PTB), although the lipid component and effect size are inconsistent between studies. It is... 
Pregnancy | Lipids | Association | Preterm birth | Genetic risk score
Journal Article
Schizophrenia Research, ISSN 0920-9964, 09/2018, Volume 199, pp. 181 - 188
Recent results imply that rare variants contribute to the risk of schizophrenia. Exome sequence data from the UK10K project was used to identify three rare,... 
Psychosis | Genetic risk | Genotyping | Sequencing
Journal Article
Biological Psychiatry, ISSN 0006-3223, 08/2017, Volume 82, Issue 3, pp. 152 - 154
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 01/2015, Volume 162, Issue 1, pp. 55 - 63
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 04/2009, Volume 106, Issue 17, pp. 7209 - 7214
The APOE epsilon 4 allele is a risk factor for late-life pathological changes that is also associated with anatomical and functional brain changes in... 
memory | hippocampus | COGNITIVELY INTACT ADULTS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | APOE EPSILON-4 ALLELE | resting connectivity | neuroimaging | POSITRON-EMISSION-TOMOGRAPHY | DEFAULT-MODE | GENETIC RISK | MEDIAL TEMPORAL-LOBE | APOLIPOPROTEIN-E POLYMORPHISM | LONG-TERM POTENTIATION | CORONARY-ARTERY-DISEASE
Journal Article
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