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1. Full Text Alteration in upper airway dilator muscle coactivation during sleep: Comparison of patients with obstructive sleep apnea and healthy subjects
by Oliven, Ron and Cohen, Guy and Dotan, Yaniv and Somri, Mostafa and Schwartz, Alan R and Oliven, Arie
Journal of Applied Physiology, ISSN 8750-7587, 02/2018, Volume 124, Issue 2, pp. 421 - 429
In patients with obstructive sleep apnea (OSA), substantial increases in genioglossus (GG) activity during hypopneas/apneas usually fail to restore normal... 
Genioglossus | Control of breathing | Obstructive sleep apnea | Pharyngeal dilators | Upper airway | obstructive sleep apnea | SPORT SCIENCES | HUMAN TONGUE | ACTIVATION | PHYSIOLOGY | genioglossus | GENIOGLOSSUS ACTIVITY | ELECTROMYOGRAM | RETRACTOR MUSCLES | PATHOGENESIS | pharyngeal dilators | ANESTHESIA | PRESSURE | upper airway | control of breathing | WAKEFULNESS | PATENCY
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2. Full Text Treating obstructive sleep apnea with hypoglossal nerve stimulation
by Eastwood, Peter R and Barnes, Maree and Walsh, Jennifer H and Maddison, Kathleen J and Hee, Geoffrey and Schwartz, Alan R and Smith, Philip L and Malhotra, Atul and McEvoy, R. Douglas and Wheatley, John R and O'Donoghue, Fergal J and Rochford, Peter D and Churchward, Tom and Campbell, Matthew C and Palme, Carsten E and Robinson, Sam and Goding, George S and Eckert, Danny J and Jordan, Amy S and Catcheside, Peter G and Tyler, Louise and Antic, Nick A and Worsnop, Christopher J and Kezirian, Eric J and Hillman, David R
Sleep, ISSN 0161-8105, 11/2011, Volume 34, Issue 11, pp. 1479 - 1486
Background: Reduced upper airway muscle activity during sleep is fundamental to obstructive sleep apnea (OSA) pathogenesis. Hypoglossal nerve stimulation... 
Sleep apnea | Genioglossus muscle | Lung | Implantable neurostimulator | Hypoglossal nerve stimulation | POPULATION | hypoglossal nerve stimulation | GENIOGLOSSUS | HEART HEALTH | ADULTS | NEUROSCIENCES | MUSCULATURE | CLINICAL NEUROLOGY | genioglossus muscle | lung | UPPER AIRWAY | ELECTRICAL-STIMULATION | BREATHING DISORDERS | QUALITY-OF-LIFE | implantable neurostimulator | ASSOCIATION | Sleep Apnea, Obstructive - therapy | Sleep Apnea, Obstructive - physiopathology | Hypoglossal Nerve - physiology | Humans | Middle Aged | Male | Treatment Outcome | Implantable Neurostimulators | Polysomnography | Electric Stimulation Therapy - methods | Quality of Life | Adult | Female | Aged | Index Medicus
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3. Full Text Respiratory movement of upper airway tissue in obstructive sleep apnea
by Brown, Elizabeth C and Cheng, Shtaokoon and McKenzie, David K and Butler, Jane E and Gandevia, Simon C and Bilston, Lynne E
Sleep, ISSN 0161-8105, 07/2013, Volume 36, Issue 7, pp. 1069 - 1076
Study Objectives: To measure real-time movement of the tongue and lateral upper airway tissues in obstructive sleep apnea (OSA) subjects during wakefulness... 
Lateral walls | Respiratory movement | Genioglossus | Dynamic imaging | Obstructive sleep apnea | ACTIVATION | genioglossus | HUMANS | ELECTROMYOGRAM | NEUROSCIENCES | NREM SLEEP | CLINICAL NEUROLOGY | dynamic imaging | respiratory movement | TONGUE | HUMAN GENIOGLOSSUS MUSCLE | MECHANICS | lateral walls | MOTOR UNITS | RESISTANCE | ONSET
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4. Full Text Mandibular muscle attachments in genial advancement surgery for obstructive sleep apnea
by Kim, Cherine H and Loree, Nichole and Han, Peter S and Ostby, Erin T and Kwon, Daniel I and Inman, Jared C
Laryngoscope, ISSN 0023-852X, 2019
Genioglossus advancement is performed in select patients with obstructive sleep apnea. Surgical techniques attempt to capture the genial tubercle of the... 
geniohyoid | genioglossus | Genial tubercle | obstructive sleep apnea surgery
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5. Full Text Acute Postoperative Negative-pressure Pulmonary Edema Reply
by Krodel, DJ and Eikermann, M
ANESTHESIOLOGY, ISSN 0003-3022, 02/2011, Volume 114, Issue 2, pp. 462 - 462
GENIOGLOSSUS | ANESTHESIOLOGY | ANTAGONISM
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6. State-dependent Versus Central Motor Effects of Ethanol on Breathing
by Vecchio, Laura Marie
11/2009
This thesis tested the hypothesis that ethanol suppresses respiratory muscle activity by effects at the central motor pool and/or by state-dependent regulation... 
genioglossus muscle | sleep | microdialysis | breathing | hypoglossal motor nucleus | 0719 | ethanol
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7. Full Text Neural memory of the genioglossus muscle during sleep is stage‐dependent in healthy subjects and obstructive sleep apnoea patients
by Taranto‐Montemurro, Luigi and Sands, Scott A and Grace, Kevin P and Azarbarzin, Ali and Messineo, Ludovico and Salant, Rebecca and White, David P and Wellman, D. Andrew
The Journal of Physiology, ISSN 0022-3751, 11/2018, Volume 596, Issue 21, pp. 5163 - 5173
In most patients with obstructive sleep apnoea (OSA), there is a spontaneous resolution of the breathing disorders during slow wave sleep (SWS) for yet unknown... 
obstructive sleep apnea | slow wave sleep | genioglossus | ACTIVATION | PHYSIOLOGY | HUMANS | SLOW-WAVE SLEEP | MECHANISMS | IDENTIFICATION | SYNAPTIC PLASTICITY | AFTERDISCHARGE | NEUROSCIENCES | LUNG-VOLUME | INTERMITTENT HYPOXIA | LONG-TERM FACILITATION | Continuous positive airway pressure | Analysis | Sleep apnea syndromes | Potentiation | Muscles | Sleep apnea | Confidence intervals | Respiratory tract | Sleep disorders | Airway management | Sleep | Apnea | Arousal | Ventilation | Respiration | Genioglossus muscle
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8. Full Text Transient upregulation of TASK‐1 expression in the hypoglossal nucleus during chronic intermittent hypoxia is reduced by serotonin 2A receptor antagonist
by Li, Wen‐Yang and Wang, Aidi and Jin, Hongyu and Zou, Ying and Wang, Zanfeng and Wang, Wei and Kang, Jian
Journal of Cellular Physiology, ISSN 0021-9541, 10/2019, Volume 234, Issue 10, pp. 17886 - 17895
Hypoglossal motoneurons innervate genioglossus muscle, the contraction of which is critical in the maintenance of upper airway patency in patients with... 
hypoglossal nucleus | chronic intermittent hypoxia | microinjection | TASK‐1 immunohistochemistry | serotonin 2A receptor antagonist | ACTIVATION | PHYSIOLOGY | TASK-1 immunohistochemistry | SLEEP-APNEA | BRAIN-STEM | CELL BIOLOGY | GENIOGLOSSUS MUSCLE-ACTIVITY | NEURONS | LONG-TERM FACILITATION | DOMAIN K+ CHANNEL | MOTONEURONS | MODULATION | Immunohistochemistry | Phenols | Sleep apnea syndromes | Gene expression | Serotonin | Muscles | Reverse transcription | Potassium channels | Muscle contraction | Contraction | Optical density | Polymerase chain reaction | Respiratory tract | Sleep disorders | Receptors | Sleep | Apnea | Hypoglossal nerve | Hypoxia | Genioglossus muscle | Potassium
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9. Full Text Neurogenic changes in the upper airway of patients with obstructive sleep apnea
by Saboisky, Julian P and Stashuk, Daniel W and Hamilton-Wright, Andrew and Carusona, Andrea L and Campana, Lisa M and Trinder, John and Eckert, Danny J and Jordan, Amy S and McSharry, David G and White, David P and Nandedkar, Sanjeev and David, William S and Malhotra, Atul
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2012, Volume 185, Issue 3, pp. 322 - 329
Rationale: Controversy persists regarding the presence and importance of hypoglossal nerve dysfunction in obstructive sleep apnea (OSA). Objectives: We... 
Tongue | Respiratory | Genioglossus | Respiration | Motor unit | motor unit | MACRO-EMG | genioglossus | NEUROMUSCULAR DISORDERS | tongue | MOTOR UNIT POTENTIALS | respiration | AMYOTROPHIC-LATERAL-SCLEROSIS | QUANTITATIVE-ANALYSIS | SOFT PALATAL MUCOSA | GENIOGLOSSUS MUSCLE | CONCENTRIC NEEDLE EMG | RESPIRATORY SYSTEM | MUSCLE-FIBER TYPE | respiratory | DIAGNOSTIC YIELD | CRITICAL CARE MEDICINE | Sleep Apnea, Obstructive - physiopathology | Motor Neurons - physiology | Humans | Tongue - physiopathology | Male | Muscle, Skeletal - innervation | Neurogenesis | Case-Control Studies | Action Potentials | Airway Remodeling | Muscle, Skeletal - physiopathology | Adult | Female | Electromyography | Hypoglossal Nerve - physiopathology | Index Medicus | Abridged Index Medicus
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10. Full Text Genial tubercle position and genioglossus advancement in obstructive sleep apnea (OSA) treatment: a systematic review
by Chang, Edward T and Kwon, Yong-Dae and Jung, Junho and Capasso, Robson and Riley, Robert and Liu, Stanley C and Camacho, Macario
Maxillofacial Plastic and Reconstructive Surgery, 12/2019, Volume 41, Issue 1, pp. 1 - 5
To systematically review the literature for methods to localize the genial tubercle as a means for performing an advancement of the genioglossus muscle.PubMed,... 
Plastic Surgery | Mandible | Genioglossus advancement | Dentistry | Oral and Maxillofacial Surgery | Genioglossus muscle | Obstructive sleep apnea | Skeletal surgery
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11. Full Text Peri‐pharyngeal muscle response to inspiratory loading: comparison of patients with OSA and healthy subjects
by Oliven, Ron and Cohen, Guy and Somri, Mostafa and Schwartz, Alan R and Oliven, Arie
Journal of Sleep Research, ISSN 0962-1105, 10/2019, Volume 28, Issue 5, pp. e12756 - n/a
Upper airway patency to airflow and the occurrence of obstructive sleep apnea involve a complex interplay between pharyngeal anatomy and synergic co‐activation... 
pharyngeal dilator muscles | styloglossus | geniohyoid | genioglossus | upper airway muscles | Comparative analysis | Sleep apnea syndromes | Index Medicus
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12. Full Text Diaphragmatic and intercostal electromyographic activity during neostigmine, sugammadex and neostigmine–sugammadex-enhanced recovery after neuromuscular blockade: A randomised controlled volunteer study
by Cammu, Guy and Schepens, Tom and De Neve, Nikolaas and Wildemeersch, Davina and Foubert, Luc and Jorens, Philippe G
European Journal of Anaesthesiology, ISSN 0265-0215, 01/2017, Volume 34, Issue 1, pp. 8 - 15
BACKGROUNDElectromyographic activity of the diaphragm (EMGdi) during weaning from mechanical ventilation is increased after sugammadex compared with... 
ANESTHESIOLOGY | GENIOGLOSSUS MUSCLE-ACTIVITY | FAILURE | REVERSAL | Index Medicus
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13. Full Text A New Agent to Reverse the Effects of Benzylisoquinoline and Steroidal Neuromuscular-blocking Agents
by Hoffmann, U and Grosse-Sundrup, M and Eikermann-Haerter, K and Zaremba, S and Ayata, C and Zhang, B and Ma, D and Isaacs, L and Eikermann, M
ANESTHESIOLOGY, ISSN 0003-3022, 08/2013, Volume 119, Issue 2, pp. 317 - 325
Introduction: To evaluate whether calabadion 1, an acyclic member of the Cucurbit[n] uril family of molecular containers, reverses benzylisoquinoline and... 
RECOVERY | SUGAMMADEX | GENIOGLOSSUS | CHEMISTRY | NEOSTIGMINE | ANESTHESIOLOGY | PULMONARY-FUNCTION | COMPLICATIONS | ION CHANNELS | BLOCKADE | MUSCLE-ACTIVITY
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14. Full Text Defining phenotypic causes of obstructive sleep apnea: Identification of novel therapeutic targets
by Eckert, Danny J and White, David P and Jordan, Amy S and Malhotra, Atul and Wellman, Andrew
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2013, Volume 188, Issue 8, pp. 996 - 1004
Rationale: The pathophysiologic causes of obstructive sleep apnea (OSA) likely vary among patients but have not been well characterized. Objectives: To define... 
Muscle | Upper airway pathophysiology | Respiratory physiology | Sleep-disordered breathing | Arousal | CONTROL STABILITY | INSTABILITY | respiratory physiology | GENIOGLOSSUS | UPPER AIRWAY COLLAPSIBILITY | HYPOGLOSSAL NERVE-STIMULATION | MECHANISMS | PATHOGENESIS | sleep-disordered breathing | COLLAPSE | RESPIRATORY SYSTEM | muscle | LOOP GAIN | upper airway pathophysiology | arousal | CRITICAL CARE MEDICINE | Respiratory System - pathology | Sleep Apnea, Obstructive - therapy | Sleep Apnea, Obstructive - physiopathology | Humans | Middle Aged | Respiratory Muscles - physiopathology | Male | Polysomnography | Respiratory System - anatomy & histology | Case-Control Studies | Sleep Apnea, Obstructive - pathology | Respiratory Muscles - pathology | Young Adult | Sleep Apnea, Obstructive - etiology | Phenotype | Adult | Female | Respiratory System - physiopathology | Aged | Index Medicus | Abridged Index Medicus
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15. Full Text Mechanisms of the deep, slow-wave, sleep-related increase of upper airway muscle tone in healthy humans
by Hicks, Amelia and Cori, Jennifer M and Jordan, Amy S and Nicholas, Christian L and Kubin, Leszek and Semmler, John G and Malhotra, Atul and McSharry, David G. P and Trinder, John A
Journal of Applied Physiology, ISSN 8750-7587, 05/2017, Volume 122, Issue 5, pp. 1304 - 1312
Upper airway muscle activity is reportedly elevated during slow-wave sleep (SWS) when compared with lighter sleep stages. To uncover the possible mechanisms... 
Tensor palatini | Upper airway muscles | Genioglossus | Slow-wave sleep | Non-rapid eye movement sleep | TENSOR-PALATINI | SPORT SCIENCES | APNEA | ACTIVATION | PHYSIOLOGY | genioglossus | DISCHARGE PATTERNS | non-rapid eye movement sleep | NEGATIVE AIRWAY | NREM SLEEP | slow-wave sleep | PRESSURE | upper airway muscles | NORMAL MEN | tensor palatini | RESISTANCE | GENIOGLOSSUS MOTOR UNITS | Muscle Tonus - physiology | Carbon Dioxide - metabolism | Reflex - physiology | Humans | Male | Muscle, Skeletal - metabolism | Muscle, Skeletal - physiology | Pressure | Polysomnography - methods | Young Adult | Respiratory System - metabolism | Airway Resistance - physiology | Sleep Stages - physiology | Adult | Respiratory System - physiopathology | Electromyography - methods | Respiration | Index Medicus | Research
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16. Full Text Metabolic activity of the tongue in obstructive sleep apnea: A novel application of FDG positron emission tomography imaging
by Kim, Andrew M and Keenan, Brendan T and Jackson, Nicholas and Chan, Eugenia L and Staley, Bethany and Torigian, Drew A and Alavi, Abass and Schwab, Richard J
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2014, Volume 189, Issue 11, pp. 1416 - 1425
Rationale: The metabolic activity of the tongue is unknown in patients with obstructive-sleep apnea (OSA). Tongue electromyographic (EMG) activity is increased... 
FDG-PET | Masseter | Genioglossus | MRI | Obstructive sleep apnea | obstructive sleep apnea | FIBER-TYPE DISTRIBUTION | genioglossus | CONTRACTILE PROPERTIES | HUMAN GENIOGLOSSUS | masseter | COMPUTED-TOMOGRAPHY | FAT QUANTIFICATION | SKELETAL-MUSCLE | UPPER AIRWAY MUSCLE | RESPIRATORY SYSTEM | AGE-RELATED-CHANGES | GLUCOSE-UPTAKE | ADIPOSE-TISSUE | CRITICAL CARE MEDICINE | Body Mass Index | Sleep Apnea, Obstructive - physiopathology | Humans | Tongue - physiopathology | Obesity - physiopathology | Muscle Relaxation | Positron-Emission Tomography - methods | Polysomnography | Case-Control Studies | Muscle Contraction | Muscle, Skeletal - physiopathology | Fluorodeoxyglucose F18 | Electromyography | Radiopharmaceuticals | Index Medicus | Abridged Index Medicus | Original
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17. Full Text What short‐term potentiation is and why it may be relevant to obstructive sleep apnoea
by Younes, Magdy
The Journal of Physiology, ISSN 0022-3751, 11/2018, Volume 596, Issue 21, pp. 5075 - 5076
genioglossus | Neural memory | treatment of sleep apnea | PHYSIOLOGY | NEUROSCIENCES | Sleep apnea syndromes | Potentiation | Sleep disorders | Sleep apnea | Sleep | Apnea
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18. Full Text Does reversal of neuromuscular block with sugammadex reduce readmission rate after surgery?
by Bose, Somnath and Xu, Xinling and Eikermann, Matthias
British Journal of Anaesthesia, ISSN 0007-0912, 03/2019, Volume 122, Issue 3, pp. 294 - 298
GENIOGLOSSUS MUSCLE-ACTIVITY | NEOSTIGMINE | RISK | ANESTHESIOLOGY | AGENTS | AIRWAY COLLAPSIBILITY | OUTCOMES | ASSOCIATION | Index Medicus
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19. Full Text Physiological mechanisms of upper airway hypotonia during REM sleep
by McSharry, David G and Saboisky, Julian P and DeYoung, Pam and Jordan, Amy S and Trinder, John and Smales, Erik and Hess, Lauren and Chamberlin, Nancy L and Malhotra, Atul
Sleep, ISSN 0161-8105, 03/2014, Volume 37, Issue 3, pp. 561 - 569
Study Objectives: Rapid eye movement (REM)-induced hypotonia of the major upper airway dilating muscle (genioglossus) potentially contributes to the worsening... 
Upper airway hypotonia | Single motor unit | Genioglossus | Rapid eye movement sleep | Obstructive sleep apnea | upper airway hypotonia | genioglossus | ADULTS | NEUROSCIENCES | single motor unit | CLINICAL NEUROLOGY | TONGUE | HUMAN GENIOGLOSSUS MUSCLE | PRESSURE | APNEA SYNDROME | RISK-FACTOR | MOTOR UNITS | DISEASE | MOVEMENT | HYPERCAPNIA | rapid eye movement sleep | Sleep Apnea, Obstructive - physiopathology | Muscle Hypotonia - physiopathology | Humans | Muscle, Skeletal - physiopathology | Tongue - physiopathology | Adult | Female | Male | Electromyography | Sleep, REM | Polysomnography | Respiration | Index Medicus
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