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NATURE IMMUNOLOGY, ISSN 1529-2908, 09/2018, Volume 19, Issue 9, pp. 910 - 911
PI3K delta regulates adaptive immune thresholds and limits immunity to endogenous microbiota. 
CELLS | DYNAMICS | DELTA SYNDROME | GERMINAL-CENTERS | IMMUNOLOGY
Journal Article
IMMUNITY, ISSN 1074-7613, 06/2011, Volume 34, Issue 6, pp. 932 - 946
The nature of follicular helper CD4(+) T (Tfh) cell differentiation remains controversial, including the minimal signals required for Tfh cell differentiation... 
B-CELLS | ACTIVATION | SAP | IN-VIVO | HUMORAL IMMUNITY | CD28 | COMMON VARIABLE IMMUNODEFICIENCY | GERMINAL-CENTERS | IMMUNOLOGY | C-MAF | IL-21
Journal Article
Blood, ISSN 0006-4971, 09/2012, Volume 120, Issue 11, pp. 2158 - 2159
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 09/2014, Volume 15, Issue 9, pp. 856 - 865
Understanding the developmental mechanisms of follicular helper T cells (T-FH cells) in humans is relevant to the clinic. However, the factors that drive the... 
B-CELLS | FOLLICULAR-HELPER-CELLS | VIVO | I INTERFERONS | AUTOIMMUNITY | SJOGRENS-SYNDROME | FACTOR BATF CONTROLS | GERMINAL-CENTERS | INDUCTION | IMMUNOLOGY | IL-12
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 02/2009, Volume 10, Issue 2, pp. 167 - 175
The inducible costimulatory molecule ICOS has been suggested to be important in the development of interleukin 17 (IL-17)producing helper T cells (T-H-17... 
B-CELLS | DEPENDENT IMMUNE-RESPONSES | MULTIPLE-SCLEROSIS | MESSENGER-RNA | IN-VIVO | COMMON VARIABLE IMMUNODEFICIENCY | INDUCIBLE COSTIMULATOR | GERMINAL-CENTERS | IMMUNOLOGY | AUTOIMMUNE ENCEPHALOMYELITIS | CUTTING EDGE
Journal Article
ARTHRITIS & RHEUMATOLOGY, ISSN 2326-5191, 04/2015, Volume 67, Issue 4, pp. 988 - 999
Objective. To assess circulating follicular helper T (Tfh)-like CD4+ T cells in patients with systemic lupus erythematosus (SLE) and determine their... 
CXC CHEMOKINE RECEPTOR-5 | B-CELLS | EFFECTOR-MEMORY | I INTERFERONS | AUTOIMMUNITY | GERMINAL-CENTERS | RHEUMATOLOGY | ANTIBODY-RESPONSES | TRANSCRIPTION FACTOR | PLASMA-CELLS | DISEASE-ACTIVITY
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2012, Volume 13, Issue 1, pp. 35 - 43
Lipid antigens trigger help from natural killer T cells (NKT cells) for B cells, and direct conjugation of lipid agonists to antigen profoundly augments... 
ACTIVATION | CYTOKINE PRODUCTION | PRECURSOR | EXPANSION | KILLER T-CELLS | SUBSETS | GERMINAL-CENTERS | COSTIMULATION | IMMUNOLOGY | ANTIBODY-RESPONSES | ANTIGEN | Physiological aspects | Antigens | Research | Glycolipids | T cells
Journal Article
ELIFE, ISSN 2050-084X, 05/2018, Volume 7
Vaccines induce memory B-cells that provide high affinity secondary antibody responses to identical antigens. Memory B-cells can also re-instigate affinity... 
HIV-1 | IMMUNE-RESPONSE | AFFINITY MATURATION | BIOLOGY | GERMINAL-CENTERS | SELECTION | EXPRESSION
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2019, Volume 202, Issue 2, pp. 428 - 440
Engagement of the BCR with Ags triggers signaling pathways for commitment of B lymphocyte responses that can be regulated, in part, by reactive oxygen species.... 
MAINTENANCE | OXIDASE | MEMORY | CHRONIC GRANULOMATOUS-DISEASE | TH2 CYTOKINES | BONE-MARROW | RECEPTOR | GERMINAL-CENTERS | STRENGTH | PROLIFERATION | IMMUNOLOGY
Journal Article
Science, ISSN 0036-8075, 08/2015, Volume 349, Issue 6249, pp. aab1253 - aab1253
An HIV-1 DNA prime vaccine, with a recombinant adenovirus type 5 (rAd5) boost, failed to protect from HIV-1 acquisition. We studied the nature of the... 
BROADLY NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | PHASE-1 SAFETY | NONNEUTRALIZING ANTIBODIES | ENVELOPE GLYCOPROTEIN | IMMUNOGENICITY EVALUATION | GERMINAL-CENTERS | DNA CANDIDATE VACCINE | DEPENDENT EPITOPE | AFFINITY B-CELLS | GP41-GP120 INTERFACE | Envelopes | Antigens | Immunoglobulins | Antibodies | Vaccines | Sequencing | Immunity | Recombinant
Journal Article
BLOOD, ISSN 0006-4971, 04/2013, Volume 121, Issue 17, pp. 3375 - 3385
Antibody responses represent a key immune protection mechanism. T follicular helper (Tfh) cells are the major CD4(+) T-cell subset that provides help to B... 
CXC CHEMOKINE RECEPTOR-5 | B-CELLS | EXTRAFOLLICULAR ANTIBODY-RESPONSES | IMMUNE-RESPONSES | BCL-6 EXPRESSION | GERMINAL-CENTERS | DIFFERENTIATION | ICOS | HEMATOLOGY | PLASMA-CELLS | MEMORY B
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2019, Volume 147, p. 104389
The use of biologic disease modifying antirheumatic drugs (bDMARDs) in systemic autoimmune diseases such as rheumatoid arthritis and at a lesser extent in... 
Antigen presentation | B cells | T cells | Ectopic germinal centers | Interferons | Costimulation
Journal Article
NEW ENGLAND JOURNAL OF MEDICINE, ISSN 0028-4793, 02/2005, Volume 352, Issue 8, pp. 804 - 815
  Our concept of the pathogenesis of chronic lymphocytic leukemia has undergone remarkable changes during the past decade. This review addresses the latest... 
B-CELL RECEPTOR | MEDICINE, GENERAL & INTERNAL | SOMATIC HYPERMUTATION | ANTIGEN-RECEPTOR | V-H GENES | GENE MUTATIONAL STATUS | CD38 EXPRESSION | GERMINAL-CENTERS | PROTEIN-TYROSINE KINASE | ZAP-70 EXPRESSION | VARIABLE-REGION MUTATIONS | Immunology | Disease | Lymphocytes | Mutation | Binding sites | Immune system | Apoptosis
Journal Article
BRITISH JOURNAL OF DERMATOLOGY, ISSN 0007-0963, 05/2016, Volume 174, Issue 5, pp. 1022 - 1029
Background Mucous membrane pemphigoid (MMP) is an uncommon mucocutaneous immunobullous disorder. Use of saliva for diagnosis by enzyme-linked immunosorbent... 
CIRCULATING IGG | AUTOANTIBODIES | DISEASE SEVERITY | SJOGRENS-SYNDROME | IMMUNOGLOBULIN | GERMINAL-CENTERS | SERUM | MUCOSAL | BP180 | PAROTID-SALIVA | DERMATOLOGY
Journal Article
Autoimmunity Reviews, ISSN 1568-9972, 01/2019, Volume 18, Issue 1, pp. 50 - 55
Myasthenia gravis (MG) is an autoimmune disease of the neuromuscular junction. Most patients have pathogenic autoantibodies against the acetylcholine receptor... 
AUTOANTIBODIES | PATHOGENESIS | ANTIBODIES | THERAPY | MYOID CELLS | THYMOMA | GERMINAL-CENTERS | MECHANISMS | THYMECTOMY | IMMUNOLOGY | EXPRESSION
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 09/2017, Volume 18, Issue 9, pp. 961 - 961
Journal Article