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Acta neuropathologica, ISSN 1432-0533, 12/2013, Volume 127, Issue 3, pp. 377 - 389
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 10/2020, Volume 531, Issue 1, pp. 56 - 61
An expanded GGGGCC hexanucleotide (G4C2) repeat within the non-coding region of C9ORF72 gene has been identified as the most common genetic cause of FTD/ALS kindred, and synthetic ligand targeting this pathological expansion sequence holds... 
GGGGCC repeat | Inter- and intrastrand binding | Mismatch binding ligand | p-NCTB | Transcription inhibition | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Carbamates | Genetic transcription | RNA | Genes | Index Medicus
Journal Article
Journal Article
Biophysical journal, ISSN 0006-3495, 08/2020, Volume 119, Issue 4, pp. 843 - 851
...) and frontotemporal dementia (FTD). This mutation can produce five dipeptide repeat proteins (DPRs), of which three are known to be toxic... 
INTRINSICALLY DISORDERED PROTEINS | DOMAIN | SEQUENCE DETERMINANTS | ANTISENSE TRANSCRIPTS | EXPANSION | ALS | NUCLEAR-IMPORT | HEXANUCLEOTIDE REPEAT | GGGGCC REPEAT | RNA FOCI | Life Sciences & Biomedicine | Biophysics | Science & Technology | Proteins | Molecular dynamics | Analysis | Dementia | Index Medicus
Journal Article
Acta neuropathologica, ISSN 1432-0533, 01/2018, Volume 135, Issue 3, pp. 445 - 457
A GGGGCC hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia... 
Pathology | Neurosciences | Medicine & Public Health | Drosophila | FTD | ALS | Repeat expansion | C9orf72 | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | C9orf72 Protein - genetics | Neurons - pathology | Animals, Genetically Modified | Introns | Cytoplasm - metabolism | Male | Cytoplasm - pathology | Frontotemporal Dementia - metabolism | DNA Repeat Expansion | Animals | Cell Nucleus - metabolism | Cell Nucleus - pathology | Amyotrophic Lateral Sclerosis - metabolism | Female | C9orf72 Protein - metabolism | Neurons - metabolism | Disease Models, Animal | Frontotemporal Dementia - pathology | RNA - metabolism | Analysis | Genes | Amyotrophic lateral sclerosis | Antisense RNA | Genetic aspects | Genetic transcription | Binding proteins | Protein binding | Transcription | Nucleotide sequence | Toxicity | Proline | Glycine | Ribonucleic acid--RNA | Proteins | RNA-binding protein | Insects | Arginine | Neurodegeneration | Polyadenylation | Dementia disorders | Codons | Frontotemporal dementia | Index Medicus | Original Paper | ablation | motor deficits | mice | bac transgenic | amyotrophic-lateral-sclerosis | dipeptide-repeat proteins | hexanucleotide repeat | nucleocytoplasmic transport | dementia | binding proteins | frontotemporal | ggggcc repeat | Neurovetenskaper
Journal Article
Trends in neurosciences (Regular ed.), ISSN 0166-2236, 05/2018, Volume 41, Issue 5, pp. 247 - 250
Journal Article