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science & technology (218) 218
life sciences & biomedicine (212) 212
animals (209) 209
girk (181) 181
neurosciences (114) 114
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g protein-coupled inwardly-rectifying potassium channels - metabolism (73) 73
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patch-clamp techniques (52) 52
g protein-coupled inwardly-rectifying potassium channels (50) 50
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nervous system (40) 40
biochemistry & molecular biology (39) 39
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dose-response relationship, drug (36) 36
fundamental and applied biological sciences. psychology (35) 35
neurons - drug effects (34) 34
proteins (34) 34
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xenopus laevis (32) 32
medical sciences (30) 30
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channel (29) 29
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cell biology (28) 28
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gtp-binding proteins - metabolism (26) 26
signal transduction (26) 26
urogenital system (26) 26
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membrane potentials - drug effects (25) 25
mice, inbred c57bl (25) 25
g protein-coupled inwardly-rectifying potassium channels - genetics (24) 24
hippocampus (23) 23
mice, knockout (23) 23
physiology (23) 23
xenopus oocyte (23) 23
cells, cultured (22) 22
dopamine (22) 22
potassium channel (22) 22
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biophysics (21) 21
g protein-coupled inwardly-rectifying potassium channels - physiology (21) 21
oocytes - metabolism (21) 21
potassium (21) 21
vertebrates: nervous system and sense organs (21) 21
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in vitro techniques (20) 20
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potassium channel blockers - pharmacology (17) 17
receptor (17) 17
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potassium channels, inwardly rectifying - metabolism (16) 16
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g protein-coupled inwardly-rectifying potassium channels - antagonists & inhibitors (15) 15
hek293 cells (15) 15
ion channel gating - physiology (15) 15
molecular sequence data (15) 15
amino acid sequence (14) 14
central nervous system (14) 14
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membrane potentials - physiology (14) 14
neurology (14) 14
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potassium channels - drug effects (14) 14
signal transduction - drug effects (14) 14
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ion channel gating - drug effects (13) 13
neuroscience (13) 13
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physiological aspects (13) 13
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neuropharmacology (12) 12
potassium channels, inwardly rectifying - genetics (12) 12
receptors, gaba-b - metabolism (12) 12
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acetylcholine (11) 11
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1. Full Text Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)
by Ha, Junghoon and Xu, Yu and Kawano, Takeharu and Hendon, Tyler and Baki, Lia and Garai, Sumanta and Papapetropoulos, Andreas and Thakur, Ganesh A and Plant, Leigh D and Logothetis, Diomedes E
The Journal of biological chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 10, pp. 3546 - 3561
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Hydrogen Sulfide - metabolism | Cricetulus | Sulfides - chemistry | Cystathionine gamma-Lyase - metabolism | Potassium Channels, Inwardly Rectifying - chemistry | Recombinant Fusion Proteins - metabolism | Oocytes - cytology | Phosphatidylinositol 4,5-Diphosphate - metabolism | G Protein-Coupled Inwardly-Rectifying Potassium Channels - metabolism | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Sulfides - metabolism | Cystathionine gamma-Lyase - genetics | Phosphatidylinositol 4,5-Diphosphate - chemistry | G Protein-Coupled Inwardly-Rectifying Potassium Channels - antagonists & inhibitors | CHO Cells | Sulfides - pharmacology | Allosteric Regulation - drug effects | Recombinant Proteins - metabolism | Hydrogen Sulfide - pharmacology | Mutagenesis, Site-Directed | Oocytes - metabolism | Hydrogen Sulfide - chemistry | Xenopus laevis | G Protein-Coupled Inwardly-Rectifying Potassium Channels - chemistry | Models, Molecular | Recombinant Proteins - chemistry | Potassium Channels, Inwardly Rectifying - genetics | Recombinant Fusion Proteins - chemistry | G Protein-Coupled Inwardly-Rectifying Potassium Channels - genetics | Molecular Dynamics Simulation | Patch-Clamp Techniques | Animals | Protein Conformation | Mice | Mutation | Potassium Channels, Inwardly Rectifying - metabolism | Amino Acid Substitution | Index Medicus | GIRK channels | Signal Transduction | phosphatidylinositol 4,5-bisphosphate (PIP2) | stroke | phosphoinositide | ischemia | KATP channels | gasotransmitters | hydrogen sulfide | potassium channel | Kir3 or GIRK channels | inwardly rectifying K+ (Kir) channels | Kir3
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2. Full Text Emerging roles for multifunctional ion channel auxiliary subunits in cancer
by Haworth, Alexander S and Brackenbury, William J
Cell calcium (Edinburgh), ISSN 0143-4160, 06/2019, Volume 80, pp. 125 - 140
Auxiliary subunit | Chloride channel | Sodium channel | Calcium channel | Potassium channel | Cancer | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus | CLC, voltage-gated chloride channel | VGCC, voltage-gated calcium channel | GIRK, G-protein inwardly rectifying potassium channel | DREAM, downstream regulatory element antagonistic modulator | CAM, cell-adhesion molecule | Kir, inwardly-rectifying potassium channel | BK, large-conductance calcium-activated potassium channel | KChIP, potassium channel interacting protein | VGKC, voltage-gated potassium channel | VGSC, voltage-gated sodium channel | CLCA, chloride channel accessory | SUR, sulfonylurea receptor | CaCC, calcium-activated chloride channel
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3. Full Text K+ channelepsy: Progress in the neurobiology of potassium channels and epilepsy
by D'Adamo, Maria Cristina and Catacuzzeno, Luigi and di Giovanni, Giuseppe and Franciolini, Fabio and Pessia, Mauro
Frontiers in cellular neuroscience, ISSN 1662-5102, 09/2013, Volume 7, pp. 134 - 134
Kv2 | Kv1 | Kv4 | Kv11(HERG) | Kv3 | Potassium channels | Kv8 | Kvβ1 | Channelopathies | KChIP LGI1 | Kir1-Kir7 (GIRK | Temporal lobe epilepsy | Autism-epilepsy | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Phenotypes | Animal models | Calcium | Nomenclature | Epilepsy | Cloning | Genes | Neurobiology | Homeostasis | Nervous system | Genetic diversity | Defects | Membrane proteins | Convulsions & seizures | Insects | Chloride channels | Physiology | Ion channels | Mutation | Potassium | absence epilepsy | GIRK | Temporal Lobe Epilepsy | Seizures
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4. Full Text Diterpene Lipo-Alkaloids with Selective Activities on Cardiac K+ Channels
by Kiss, Tivadar and Borcsa, Botond and Orvos, Péter and Tálosi, László and Hohmann, Judit and Csupor, Dezső
Planta medica, ISSN 0032-0943, 11/2017, Volume 83, Issue 17, pp. 1321 - 1328
Biological and Pharmacological Activity | diterpene alkaloid | hERG | GIRK | Aconitum species | lipo-alkaloid | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Diterpenes - pharmacology | Plants, Medicinal - chemistry | Alkaloids - pharmacology | Plant Extracts - pharmacology | Humans | Alkaloids - chemical synthesis | Structure-Activity Relationship | Potassium Channels - drug effects | Aconitum - chemistry | Patch-Clamp Techniques | HEK293 Cells | Heart - drug effects | Diterpenes - chemical synthesis | Diterpenes | Ion channels | Research | Analysis | Structure-activity relationships (Biochemistry) | Index Medicus
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5. Full Text GIRK channels mediate the nonphotic effects of exogenous melatonin
by Hablitz, Lauren M and Molzof, Hylton E and Abrahamsson, Xkathryn E and Cooper, Joanna M and Prosser, Rebecca A and Gamble, Xkaren L
The Journal of neuroscience, ISSN 0270-6474, 11/2015, Volume 35, Issue 45, pp. 14957 - 14965
Suprachiasmatic nucleus | Entrainment | Melatonin | Nonphotic | GIRK | Circadian | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Indenes - pharmacology | Suprachiasmatic Nucleus - drug effects | Melatonin - agonists | Bee Venoms - pharmacology | Mice, Inbred C57BL | Male | G Protein-Coupled Inwardly-Rectifying Potassium Channels - physiology | Mice, Knockout | Suprachiasmatic Nucleus - physiology | Animals | G Protein-Coupled Inwardly-Rectifying Potassium Channels - agonists | Mice | Melatonin - pharmacology | G Protein-Coupled Inwardly-Rectifying Potassium Channels - antagonists & inhibitors | Organ Culture Techniques | Potassium Channel Blockers - pharmacology | Index Medicus | nonphotic | circadian | melatonin | suprachiasmatic nucleus | entrainment
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6. Full Text Cholesterol Binding Sites in Inwardly Rectifying Potassium Channels
by Rosenhouse-Dantsker, Avia
05/2019, Advances in Experimental Medicine and Biology, ISBN 9783030142643, Volume 1135
Channel modulation | Ion channels | Kir channels | GIRK channels | Protein–lipid interaction | Cholesterol
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7. Full Text Role of A1 receptor-activated GIRK channels in the suppression of hippocampal seizure activity
by Hill, Emily and Hickman, Charlotte and Diez, Rebecca and Wall, Mark
Neuropharmacology, ISSN 0028-3908, 03/2020, Volume 164, pp. 107904 - 107904
GIRK channel | Adenosine | Hippocampus | Seizures | Index Medicus
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8. Full Text GABAB Receptor Coupling to G-proteins and Ion Channels
by Padgett, Claire L and Slesinger, Paul A
2010, ISBN 9780123786470, Volume 58, Issue C
pertussis toxin | GIRK | GABAB receptors | heterodimer | voltage-gated Ca2+ channel | desensitization | Desensitization | receptors | GABA | channel | Voltage-gated Ca | Heterodimer | Pertussis toxin | Multiprotein Complexes - metabolism | Animals | Ion Channels - metabolism | Signal Transduction | Humans | GTP-Binding Proteins - metabolism | Receptors, GABA-B - chemistry | Receptors, GABA-B - metabolism | Index Medicus
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