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Journal of Organic Chemistry, ISSN 0022-3263, 05/1998, Volume 63, Issue 10, pp. 3281 - 3286
The strongly cytotoxic, antibiotic, and immunosuppressive palau'amine was isolated from the Belau sponge Stylotella aurantium, along with less active I-bromo... 
GIROLLINE | METABOLITES | KIRKPATRICKIA-VARIALOSA | CRYSTAL-STRUCTURE | NATURAL-PRODUCTS | PHAKELLIA SP | COMPOUND | PSEUDAXINYSSA-CANTHARELLA | CHEMISTRY, ORGANIC | INHIBITORS | ALKALOIDS | Alkaloids | Sponges | Research | Aromatic compounds
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2004, Volume 45, Issue 44, pp. 8149 - 8152
Journal Article
Tetrahedron, ISSN 0040-4020, 2002, Volume 58, Issue 21, pp. 4201 - 4215
2-Aminothiazole analogs of the natural antitumor agent, girolline, were prepared in natural stereochemistry series (threo) and in a non-natural series... 
antitumor compounds | marine metabolite | structure–activity | aminothiazole | Marine metabolite | Structure-activity | Aminothiazole | Antitumor compounds | GIROLLINE | ALCOHOLS | CHEMISTRY, ORGANIC | structure-activity
Journal Article
Synthesis, ISSN 0039-7881, 1/2005, Volume 2005, Issue 1, pp. 97 - 101
Abstract Aminothiazole analogues of the antitumor alkaloid girolline have been asymmetrically synthesised using the chiral pool. The key-steps involved the... 
paper | Girolline | Chiral pool | Structure-activity relationships | Aminothiazole | Antitumor | structure-activity relationships | antitumor | aminothiazole | CONFIGURATION | CHEMISTRY, ORGANIC | girolline | CLEAVAGE | DERIVATIVES | chiral pool
Journal Article
The Journal of Organic Chemistry, ISSN 0022-3263, 11/1997, Volume 62, Issue 23, pp. 7918 - 7919
Journal Article
TETRAHEDRON, ISSN 0040-4020, 06/1997, Volume 53, Issue 22, pp. 7605 - 7614
Through a general synthetic scheme, hymenidin, oroidin and keramadine, all marine 2-aminoimidazole metabolites were prepared. Seven steps from... 
GIROLLINE | K EE CHEMISTRY, ORGANIC | marine 2-aminoimidazole | keramadine | oroidin | CHEMISTRY, ORGANIC | IMIDAZOLES | hymenidin
Journal Article
Biological & Pharmaceutical Bulletin, ISSN 0918-6158, 2004, Volume 27, Issue 5, pp. 699 - 701
Girolline, an antitumor compound isolated from a sponge, has been reported to inhibit the termination step of protein synthesis in vivo. In this study, we... 
Journal Article
Journal of Natural Products, ISSN 0163-3864, 03/1997, Volume 60, Issue 3, pp. 290 - 291
Four minor polar nitrogen compounds have been isolated from the New Caledonian marine sponge, Cymbastela cantharella. Three are the known products allantoin,... 
K DE PLANT SCIENCES | METABOLITES | CHEMISTRY, MEDICINAL | PHLOEODICTYON SP | GUANIDINE ALKALOIDS | PSEUDAXINYSSA-CANTHARELLA | IDENTIFICATION | K DX CHEMISTRY, MEDICINAL | PLANT SCIENCES | GIROLLINE | CRAMBINE-C1 | CRAMBE-CRAMBE | NEO-CALEDONIAN LAGOONS | PHARMACOLOGY & PHARMACY | K TU PHARMACOLOGY & PHARMACY | INVERTEBRATES
Journal Article
TETRAHEDRON, ISSN 0040-4020, 05/1992, Volume 48, Issue 21, pp. 4327 - 4346
Desaminogirollines syn 2'S,3'S and 2'R,3'R have been prepared from N1-camphosulfonamide 4-carboxaldehyde imidazole and their diastereoisomeric derivatives have... 
2-AMINOIMIDAZOLE | 4[1',2',3'-TRIHYDROXYPROPYL]IMIDAZOLE | CHEMISTRY, ORGANIC | GIROLLINE SYNTHESIS | D(-)ARABINOSE | RHODIUM REDUCTION
Journal Article
BULLETIN DES SOCIETES CHIMIQUES BELGES, ISSN 0037-9646, 09/1997, Volume 106, Issue 9-10, pp. 553 - 557
The reaction of 1-methyl-1-cyanohydrazones with methyl trifluoromethane sulfonate allows the direct preparation of 2-(methylamino)-1-methyl imidazoles as their... 
GIROLLINE | AGENT | SPONGE HYMENIACIDON SP | MARINE | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
BULLETIN DE LA SOCIETE CHIMIQUE DE FRANCE, ISSN 0037-8968, 1994, Volume 131, Issue 5, pp. 590 - 599
The synthesis of 2-aminoimidazole marine metabolites has induced various studies on the reactivity of the imidazole nucleus, especially in positions 2 and... 
SPONGE HYMENIACIDON SP | ANTAGONIST | NATURAL-PRODUCTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPOUND | PSEUDAXINYSSA-CANTHARELLA | CHEMISTRY, ORGANIC | GIROLLINE | AGENT | 2-AMINOIMIDAZOLES | AZIDATION | CLATHRODINE | CHEMISTRY | PORIFERA | SEROTONERGIC RECEPTORS | COPULATION AZOIQUE
Journal Article
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