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index medicus (63) 63
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rats (44) 44
gk rat (29) 29
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glucokinase (28) 28
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activation (6) 6
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gk activators (6) 6
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stimulated insulin-secretion (6) 6
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Journal Article
Biochemical Journal, ISSN 0264-6021, 1760, Volume 459, Issue 3, pp. 551 - 564
Hepatic glucose phosphorylation by GK (glucokinase) is regulated by GKRP (GK regulatory protein). GKRP forms a cytosolic complex with GK followed by nuclear... 
Allosteric regulation | Fructose phosphate ester | Glucokinase regulatory protein | Glucokinase | Metabolic regulation | Diabetes | Co-operativity | RAT-LIVER | GLYCEMIC CONTROL | ACTIVATION | fructose phosphate ester | BIOCHEMISTRY & MOLECULAR BIOLOGY | allosteric regulation | co-operativity | glucokinase regulatory protein | HEPATIC GLUCOKINASE | P446L VARIANT | FRUCTOSE | HUMAN GLUCOKINASE | STRUCTURAL BASIS | GLUCOSE | DIABETES THERAPY | diabetes | glucokinase | metabolic regulation | Adaptor Proteins, Signal Transducing - chemistry | Protein Unfolding | Allosteric Regulation | Humans | Protein Multimerization | Tryptophan - chemistry | Fructosephosphates - metabolism | Protein Interaction Domains and Motifs | Protein Stability | Glucokinase - chemistry | Recombinant Proteins - metabolism | Protein Refolding | Models, Molecular | Recombinant Proteins - chemistry | Spectrometry, Fluorescence | Glucokinase - genetics | Mutant Proteins - metabolism | Glucokinase - metabolism | Protein Transport | Mutant Proteins - chemistry | Adaptor Proteins, Signal Transducing - genetics | Glucose - metabolism | Ligands | Protein Conformation | Adaptor Proteins, Signal Transducing - metabolism | Amino Acid Substitution | Index Medicus | T2D, Type 2 diabetes | WT, wild-type | rGKRP, rat GKRP | NPC, nuclear pore complex | PPI, protein–protein interaction | NATA, N-acetyl-L-tryptophanamide | xGKRP, Xenopus GKRP | MH, D-mannoheptulose | GKA, GK activator | hGK, human GK | F6P, fructose 6-phosphate | hGKRP, human GKRP | GCKR | xGK, Xenopus GK | GKRPI, GKRP inhibitor | GK, glucokinase | TF, tryptophan fluorescence | GCK | GKRP, GK regulatory protein | SIS, sugar isomerase | F1P, fructose 1-phosphate
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 06/2014, Volume 1843, Issue 6, pp. 1123 - 1134
Journal Article
Journal Article
Computational Biology and Chemistry, ISSN 1476-9271, 04/2018, Volume 73, pp. 221 - 229
Glucokinase (GK) is the main enzyme which controls the blood glucose levels in a safe and narrow physiological range in humans. GK activators are the novel... 
GK activators | Diabetes | Thiazole-2-yl benzamides | Antidiabetic activity | Glucokinase | DOCKING | IDENTIFICATION | UREA DERIVATIVES | DISCOVERY | POTENT | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | BIOLOGY | REGULATORY PROTEIN | PPAR-GAMMA | AGENTS | TYPE-2 DIABETES-MELLITUS | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 1999, Volume 456, Issue 2, pp. 332 - 338
Journal Article
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2006, Volume 393, Issue 1, pp. 389 - 396
Journal Article
Journal Article
FRONTIERS IN NEUROSCIENCE, ISSN 1662-453X, 03/2019, Volume 13, pp. 275 - 275
Glucose homeostasis is performed by specialized cells types that detect and respond to changes in systemic glucose concentration. Hepatocytes, beta-cells and... 
RAT-LIVER | TRANSLOCATION | GLUCOKINASE REGULATORY PROTEIN | glucosensing | GLUCOSE SENSOR | NUCLEAR EXPORT | GK regulatory protein | NEUROSCIENCES | FASTING GLUCOSE | INSULIN | MESSENGER-RNAS | tanycytes | HEPATIC GLUCOKINASE | PANCREATIC BETA-CELLS | metabolic | glucokinase | Isoenzymes | Dextrose | Glucose
Journal Article