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Journal Article
Immunologic Research, ISSN 0257-277X, 10/2011, Volume 51, Issue 1, pp. 45 - 60
Complement system activation plays an important role in both innate and acquired immunity. Activation of the complement and the subsequent formation of C5b-9... 
Allergology | Signal transduction | Immunology | Medicine & Public Health | Cell cycle | Internal Medicine | Membrane attack complex | C5b-9 terminal complement complex | Transcriptional regulation | Medicine/Public Health, general | Apoptosis | ACTIVATED PROTEIN-KINASE | SYSTEMIC LUPUS-ERYTHEMATOSUS | GUILLAIN-BARRE-SYNDROME | ULCERATIVE-COLITIS | GLOMERULAR EPITHELIAL-CELLS | C5B-9 COMPLEX | IMMUNOLOGY | S-PROTEIN | MANNAN-BINDING LECTIN | ACUTE MYOCARDIAL-INFARCTION | SMOOTH-MUSCLE-CELLS | Forkhead Transcription Factors - immunology | CDC2 Protein Kinase | Complement Membrane Attack Complex - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Caspase 8 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Complement Membrane Attack Complex - immunology | MAP Kinase Signaling System - immunology | Phosphatidylinositol 3-Kinases - immunology | Cell Cycle Proteins - immunology | Cyclin B - immunology | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | bcl-Associated Death Protein - metabolism | Cell Membrane - metabolism | Phosphorylation - immunology | Cyclin-Dependent Kinases | Proto-Oncogene Proteins c-akt - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Muscle Proteins - immunology | G1 Phase - immunology | S Phase - immunology | Nerve Tissue Proteins - immunology | Cell Cycle Proteins - metabolism | bcl-Associated Death Protein - immunology | Cyclin-Dependent Kinase 4 - metabolism | Nerve Tissue Proteins - metabolism | Caspase 8 - immunology | Animals | Apoptosis - immunology | Proto-Oncogene Proteins c-akt - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | BH3 Interacting Domain Death Agonist Protein - immunology | Cyclin B - metabolism | Cell Membrane - immunology | Forkhead Box Protein O1 | Cyclin-Dependent Kinase 2 - immunology | Medical colleges | Membranes | Immune system | apoptosis | membrane attack complex | cell cycle | signal transduction | transcriptional regulation
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2011, Volume 121, Issue 6, pp. 2181 - 2196
Diabetic nephropathy (DN) is among the most lethal complications that occur in type 1 and type 2 diabetics. Podocyte dysfunction is postulated to be a critical... 
EPITHELIAL-MESENCHYMAL TRANSITION | KIDNEY-DISEASE | MAMMALIAN TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | TUBEROUS SCLEROSIS COMPLEX | SLIT DIAPHRAGM | GLOMERULAR PROTEIN | ANGIOTENSIN-II | NEPHRIN EXPRESSION | ENDOPLASMIC-RETICULUM STRESS | NEPHROTIC SYNDROME | Phosphorylation | Ribosomal Protein S6 Kinases - metabolism | Diabetic Nephropathies - etiology | Diabetes Mellitus, Type 2 - genetics | Multiprotein Complexes | Podocytes - enzymology | Diabetic Nephropathies - drug therapy | Endoplasmic Reticulum - metabolism | Male | Mechanistic Target of Rapamycin Complex 1 | Mice, Mutant Strains | Tumor Suppressor Proteins - deficiency | Tumor Suppressor Proteins - genetics | Glomerular Basement Membrane - pathology | Regulatory-Associated Protein of mTOR | Cell Differentiation | Membrane Proteins - metabolism | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Type 2 - complications | Disease Models, Animal | Carrier Proteins - physiology | Proteins - physiology | Sirolimus - therapeutic use | Mice, Inbred C57BL | Podocytes - pathology | Mice, Knockout | Carrier Proteins - genetics | Tumor Suppressor Proteins - physiology | Adaptor Proteins, Signal Transducing | Glomerular Mesangium - pathology | Animals | Podocytes - drug effects | Podocytes - physiology | Mice | Protein Processing, Post-Translational | TOR Serine-Threonine Kinases | Enzyme Activation | Proteins - antagonists & inhibitors | Diabetic nephropathies
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2003, Volume 23, Issue 14, pp. 4917 - 4928
Journal Article
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 1931-857X, 08/2006, Volume 291, Issue 2, pp. 422 - 428
Vascular endothelial growth factor (VEGF-A) signaling is required for endothelial cell differentiation, vasculogenesis, angiogenesis, and vascular patterning.... 
VEGF receptor 2 | VEGF-A secretion | Slit diaphragm proteins | Cell differentiation | Apoptosis | cell differentiation | PHYSIOLOGY | SLIT DIAPHRAGM | NEPHRIN | GLOMERULAR PROTEIN | TYROSINE KINASE | apoptosis | RECEPTOR | IN-VITRO | EPITHELIAL-CELLS | UROLOGY & NEPHROLOGY | NEPHROTIC SYNDROME | EXPRESSION | slit diaphragm proteins | ENDOTHELIAL GROWTH-FACTOR | Cytoskeletal Proteins | Receptors, Vascular Endothelial Growth Factor - physiology | Nerve Tissue Proteins - analysis | Vascular Endothelial Growth Factor Receptor-1 - physiology | RNA, Messenger - analysis | Neuropilin-2 - analysis | Proteins - analysis | Vascular Endothelial Growth Factor A - genetics | Membrane Proteins - analysis | Proto-Oncogene Proteins c-akt - genetics | Vascular Endothelial Growth Factor A - secretion | Vascular Endothelial Growth Factor Receptor-2 - genetics | Neuropilin-2 - physiology | Membrane Proteins - physiology | Neuropilin-2 - genetics | Vascular Endothelial Growth Factor Receptor-2 - physiology | Receptors, Vascular Endothelial Growth Factor - genetics | C-Reactive Protein - analysis | Cell Differentiation - physiology | Cell Survival - physiology | Podocytes - chemistry | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Line | Proteins - physiology | Nerve Tissue Proteins - physiology | Receptors, Vascular Endothelial Growth Factor - analysis | Vascular Endothelial Growth Factor Receptor-2 - analysis | Membrane Proteins - genetics | RNA, Messenger - genetics | Gene Expression Regulation - physiology | Intracellular Signaling Peptides and Proteins | Vascular Endothelial Growth Factor A - analysis | C-Reactive Protein - genetics | Proto-Oncogene Proteins c-akt - physiology | C-Reactive Protein - physiology | Nerve Tissue Proteins - genetics | Podocytes - cytology | Proteins - genetics | Adaptor Proteins, Signal Transducing | Animals | Podocytes - physiology | Vascular Endothelial Growth Factor Receptor-1 - analysis | Proto-Oncogene Proteins c-akt - analysis | Signal Transduction - physiology | Mice | Vascular Endothelial Growth Factor A - physiology
Journal Article
The EMBO Journal, ISSN 0261-4189, 10/2007, Volume 26, Issue 19, pp. 4215 - 4227
TSG101 and ALIX both function in HIV budding and in vesicle formation at the multivesicular body (MVB), where they interact with other Endosomal Sorting... 
ESCRT pathway | midbody | abscission | cytokinesis | CEP55 | Cytokinesis | Midbody | Abscission | HIV-1 P6 | LATE-BUDDING DOMAINS | COMPLEX | TSG101 | BIOCHEMISTRY & MOLECULAR BIOLOGY | RELEASE | CELL BIOLOGY | MULTIVESICULAR BODIES | MONOCYTE-DERIVED MACROPHAGES | CELL-CYCLE | CD2-ASSOCIATED PROTEIN | GLOMERULAR-DISEASE | Proteins | Cellular biology | Molecular biology | Cell cycle
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2006, Volume 103, Issue 46, pp. 17079 - 17086
Journal Article