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Publication Date Publication Date
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11/2011
The incretin hormone glucagon-like peptide-1 enhances glucose-dependent insulin secretion and is therefore a most attractive therapeutic approach for the... 
GLP-1 | metformin | 0719
Dissertation
03/2014
Our laboratory has demonstrated previously that the proglucagon gene (gcg), which encodes the incretin hormone GLP-1, is among the downstream targets of the... 
Pak1 | GLP-1 | 0719 | Gcg | Diabetes
Dissertation
06/2010
Cardioprotective effects of glucagon-like peptide-1 (GLP-1), the GLP-1 receptor (GLP-1R) agonist exendin-4 (Ex-4), and GLP-1(9-36), a cleavage product of... 
ischemia reperfsuion | GLP-1
Dissertation
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 02/2018, Volume 496, Issue 3, pp. 898 - 903
Glucagon-like peptide 1 (GLP-1), an incretin gastrointestinal hormone, is secreted when stimulated by nutrients including metabolizable sugars such as glucose... 
Allulose | GLP-1 | GIP
Journal Article
Development of new incretin drugs: promising therapies, 12/2006
New agents are being added to the armamentarium of drugs used for the treatment of diabetes mellitus. Today, extensive research is being conducted on incretin... 
Diabetes mellitus, GLP-1, GIP, DPP-IV
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 7113 - 7125
We here reported 2 novel Xenopus glucagon-like peptide-1 (xGLP-1) analogs, xGLP159 and xGLP296, whose therapeutic effects on metabolic efficacy and glycemic... 
metabolic disease | antidiabetic | GLP-1 | DESIGN | GLP-1 RECEPTOR AGONISTS | Xenopus GLP-1 | FOOD-INTAKE | STABILITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISCOVERY | CELL BIOLOGY | BODY-WEIGHT | OBESITY | EXENDIN-4 | BIOLOGY | NAUSEA | DERIVATIVES
Journal Article
DIABETES OBESITY & METABOLISM, ISSN 1462-8902, 06/2012, Volume 14, Issue 6, pp. 531 - 538
Aim: Previous studies with the novel once daily glucagon-like peptide-1 (GLP-1) analogue liraglutide and the GLP-1 receptor agonist exenatide have revealed... 
GLP-1 | HEALTHY-SUBJECTS | HUMAN GLP-1 ANALOG | FOOD-INTAKE | RATS | appetite control | MEAL SIZE | AREA POSTREMA | DIABETIC-PATIENTS | DERIVATIVE LIRAGLUTIDE | GLUCAGON-LIKE PEPTIDE-1 | GLP-1 analogue | ENDOCRINOLOGY & METABOLISM | antidiabetic drug | BETA-CELL MASS | incretin therapy | exenatide
Journal Article
11/2013
G-protein coupled receptors (GPCRs) have been shown to interact with an array of accessory proteins that modulate their function. I hypothesize that the... 
Protein Interactions | 0379 | 0410 | GLP-1 Receptor
Dissertation
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, ISSN 1619-7070, 07/2010, Volume 37, Issue 7, pp. 1345 - 1355
Insulinomas are neuroendocrine tumours derived from pancreatic beta-cells. The glucagon-like peptide 1 receptor (GLP-1R) is expressed with a high incidence (>... 
LOCALIZATION | NEUROENDOCRINE TUMORS | Insulinoma | GLP-1 receptor | GLP-1 BINDING-SITES | PEPTIDE-1 GLP-1 | SPECT | GA-68 | RECEPTOR SCINTIGRAPHY | Imaging | Exendin | LIGAND | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET
Journal Article
Medicina Clínica, ISSN 0025-7753, 2014, Volume 143, pp. 8 - 11
Resumen La modulación del efecto incretina ha abierto una nueva estrategia en el tratamiento de la diabetes mellitus tipo 2 (DM2). La potenciación de este... 
Internal Medicine | Inhibidor DPP-4 | Incretin | Incretina | GLP-1 | Glucagon | Análogo receptor GLP-1 | GLP-1 analog | Glucagón | Gastric emptying | Vaciamiento gástrico | GIP | GLP-1 analog receptor | DPP-4 inhibitor | Análogo GLP-1 | Diabetes
Journal Article
Medicina clínica, ISSN 0025-7753, 2014, Volume 143, Issue 143, pp. 8 - 11
Modulation of the incretin effect has opened up a new strategy in the treatment of diabetes mellitus type 2 (DM2). To date, this physiological mechanism has... 
Incretin | Inhibidor DPP-4 | Incretina | GLP-1 | Glucagon | Análogo receptor GLP-1 | GLP-1 analog | Glucagón | Gastric emptying | Vaciamiento gástrico | GIP | GLP-1 analog receptor | DPP-4 inhibitor | Análogo GLP-1 | Diabetes
Journal Article
Diabetologia, ISSN 0012-186X, 10/2017, Volume 60, Issue 10, pp. 2066 - 2075
Journal Article
Medicina clínica, ISSN 0025-7753, 2014, Volume 143, Issue 143, pp. 12 - 17
Glucagon-like peptide 1 (GLP-1) is secreted from enteroendocrine L-cells in response to oral nutrient intake and elicits glucose-stimulated insulin secretion... 
Postprandial effect | Agonistas del receptor de GLP-1 | GLP-1 | DPP-4 | Duration of effect | Exendin-4 | Efecto posprandial | Análogos del GLP-1 | Individualization of drug therapy | Duración de efecto | GLP-1 receptor agonists | Exendina-4 | Individualización terapéutica | GLP-1 analogs
Journal Article
Endocrine Journal, ISSN 0918-8959, 2017
Canagliflozin has a robust inhibitory effect on sodium glucose transporter (SGLT)-2 and a mild inhibitory effect on SGLT1. The main purpose of this study was... 
GLP-1 | Canagliflozin | SGLT1 | GIP
Journal Article
Medicina Clínica, ISSN 0025-7753, 2014, Volume 143, pp. 12 - 17
Resumen El péptido similar al glucagón-1 (GLP-1) es secretado por células L entero-endocrinas tras la ingestión oral de nutrientes y potencia la secreción de... 
Internal Medicine | Postprandial effect | Agonistas del receptor de GLP-1 | GLP-1 | DPP-4 | Duration of effect | Exendin-4 | Efecto posprandial | Análogos del GLP-1 | Individualization of drug therapy | Duración de efecto | GLP-1 receptor agonists | Exendina-4 | Individualización terapéutica | GLP-1 analogs
Journal Article
LIVER INTERNATIONAL, ISSN 1478-3223, 10/2011, Volume 31, Issue 9, pp. 1285 - 1297
Background/Aims: High-fat dietary intake and low physical activity lead to insulin resistance, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic... 
GLP-1 receptor | MECHANISMS | NASH | LIVER-DISEASE | hepatic lipid oxidation | INCRETIN SYSTEM | OBESITY | GLUCOSE-METABOLISM | INSULIN-RESISTANCE | high-fat diet | GLP-1 RECEPTORS | MICE | GASTROENTEROLOGY & HEPATOLOGY | TYPE-2 DIABETES-MELLITUS | ADIPOSE-TISSUE
Journal Article
11/2013
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by the enteroendocrine L-cell that potently stimulates insulin secretion. Although signaling... 
GLP-1 | 0719 | VAMP2 | SNARE
Video Recording
11/2013
Cardiovascular disease is the most common cause of morbidity and mortality in type 2 diabetes. Short-term studies of glucagon-like peptide-1 (GLP-1)-targeted... 
cardiovascular disease | GLP-1 | type 2 diabetes | 0719 | platelet function
Dissertation
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