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Journal of Hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Summary Bile acid (BA) transporters are critical for maintenance of the enterohepatic BA circulation where BAs exert their multiple physiological functions... 
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | RAT-LIVER | SALT EXPORT PUMP | GROWTH-FACTOR 19 | ORGANIC ANION TRANSPORTERS | 90-PERCENT PARTIAL-HEPATECTOMY | URSODEOXYCHOLIC ACID | PRIMARY BILIARY-CIRRHOSIS | FARNESOID-X-RECEPTOR | GASTROENTEROLOGY & HEPATOLOGY | PHOSPHOLIPID-ASSOCIATED CHOLELITHIASIS | FAMILIAL INTRAHEPATIC CHOLESTASIS | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
Journal Article
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 8/2015, Volume 388, Issue 8, pp. 883 - 903
G-protein coupled receptors (GPCRs) are the targets of over half of all prescribed drugs today. The UniProt database has records for about 800 proteins... 
Neurosciences | CXCR 1 , CXCR 2 , CCR 4 and CCR 5 , chemokine receptors | TM, trans-membrane helix | β 2 AR, β 2 -adrenergic receptor | ProS, pairwise protein similarity method | CRF1, corticotropin releasing factor receptor 1 | T4L, T4-lysozyme | ECL, extracellular loop | GLP-1, Glucagon-like peptide-1 receptor | hM 3 R, human muscarinic M3 receptor | α1B Adrenergic receptor | Pharmacology/Toxicology | 7TM, seven-transmembrane domain | HGMP, hierarchical GPCR modelling protocol | PDB, Protein Data Bank | XFELs, x-ray free electron lasers | 5-HT 2B and 5-HT 2C , human 5-hydroxytryptamine receptors 2B and 2C, respectively | GLAS, GPCR-likeness assessment score | H 1 , histamine receptor 1 | 3D, three-dimensional | Biomedicine | CCK 2 R, cholecystokinin receptor-2 | MD, molecular dynamic simulations | GPCRs, G-protein coupled receptors | Dopamine D 2 receptor | BRIL, apocytochrome b 562 RIL | δ-OR, delta-opioid receptor | SDM, site-directed mutagenesis | CCK2R, cholecystokinin receptor-2 | PEPTIDE-1 RECEPTOR | DESIGN | CXCR1, CXCR2, CCR4, and CCR5, chemokine receptors | beta 2AR, beta 2-adrenergic receptor | hMR, human muscarinic M3 receptor | HUMAN OREXIN-1 | PHARMACOLOGY & PHARMACY | ANTAGONISTS | Dopamine D-2 receptor | PROTEIN-COUPLED RECEPTORS | SITE-DIRECTED MUTAGENESIS | alpha 1B Adrenergic receptor | LIPIDIC CUBIC PHASE | delta-OR, delta-opioid receptor | 5-HT2B and 5-HT2C, human 5-hydroxytryptamine receptors 2B and 2C, respectively | H-1, histamine receptor 1 | SERIAL FEMTOSECOND CRYSTALLOGRAPHY | BINDING | SELECTIVITY | BRIL, apocytochrome bRIL | Animals | Receptors, G-Protein-Coupled - metabolism | Computer Simulation | Drug Industry | Humans | Cooperative Behavior | Models, Molecular | Crystallography | Drug Discovery | Universities | Drug discovery | BRIL, apocytochrome b562RIL | Meeting Report | H1, histamine receptor 1 | β2AR, β2-adrenergic receptor | CXCR1, CXCR2, CCR4 and CCR5, chemokine receptors | hM3R, human muscarinic M3 receptor | Dopamine D2 receptor
Journal Article
Biochemistry, ISSN 0006-2960, 02/2018, Volume 57, Issue 8, pp. 1410 - 1422
The calcitonin receptor-like receptor (CLR) is a class B G protein-coupled receptor (GPCR) that forms the basis of three pharmacologically distinct receptors,... 
GENE-RELATED PEPTIDE | GLUCAGON-LIKE PEPTIDE-1 | 3RD EXTRACELLULAR LOOP | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-TERMINUS | GLP-1 RECEPTOR | CRYO-EM STRUCTURE | MUTATIONAL ANALYSIS | CGRP RECEPTOR | BINDING | Molecules | Usage | Calcitonin | Analysis | Ligands (Biochemistry) | G proteins | Research | Peptide hormones
Journal Article
European Journal of Nuclear Medicine and Molecular Imaging, ISSN 1619-7070, 4/2013, Volume 40, Issue 4, pp. 524 - 531
Journal Article
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 04/2016, Volume 18, Issue 4, pp. 317 - 332
Journal Article