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Journal of Biological Chemistry, ISSN 0021-9258, 09/2009, Volume 284, Issue 38, pp. 25593 - 25601
Glucocorticoids are important regulators of lipid homeostasis, and chronically elevated glucocorticoid levels induce hypertriglyceridemia, hepatic steatosis,... 
OBESITY | PLASMA | GENE | CHROMATIN | ANGIOGENESIS | DIET | BIOCHEMISTRY & MOLECULAR BIOLOGY | HYPERLIPIDEMIA | MICE | TRANSCRIPTIONAL REGULATION | PROTEIN-4 | Transcription, Genetic - drug effects | Hypertriglyceridemia - genetics | Humans | Dexamethasone - adverse effects | Receptors, Glucocorticoid - metabolism | Hepatocytes - metabolism | Fatty Liver - chemically induced | Adipose Tissue - metabolism | Angiopoietin-like 4 Protein | Dexamethasone - pharmacology | Glucocorticoids - genetics | Glucocorticoids - metabolism | Response Elements - genetics | Lipoprotein Lipase - metabolism | Glucocorticoids - adverse effects | Fatty Liver - genetics | Angiopoietins - metabolism | Fatty Liver - metabolism | Lipoprotein Lipase - genetics | Liver - metabolism | Rats | Hypertriglyceridemia - metabolism | Mice, Knockout | Triglycerides - metabolism | Adipose Tissue, White | Hypertriglyceridemia - chemically induced | Animals | Receptors, Glucocorticoid - genetics | Cell Line, Tumor | Dexamethasone - metabolism | Glucocorticoids - pharmacology | Mice | Transcription, Genetic - genetics | Triglycerides - genetics | Angiopoietins - genetics | Index Medicus | Lipids and Lipoproteins | Metabolism, Regulation, and Signaling | Transcription | Dermatologi och venereologi | Dermatology and Venereal Diseases | Dexamethasone/adverse effects/metabolism/pharmacology | Hypertriglyceridemia/chemically induced/genetics/metabolism | Receptors | Adipose Tissue/metabolism | Liver/metabolism | Tumor | Adipose Tissue | Cell Line | Fatty Liver/chemically induced/genetics/metabolism | Triglycerides/genetics/ metabolism | Response Elements/genetics | Angiopoietins/genetics/ metabolism | Knockout | Lipoprotein Lipase/genetics/metabolism | White | Hepatocytes/metabolism | Genetic/drug effects/genetics | Glucocorticoids/adverse effects/genetics/ metabolism/pharmacology | Glucocorticoid/genetics/ metabolism
Journal Article
Journal Article
PLoS biology, ISSN 1544-9173, 10/2015, Volume 13, Issue 10, pp. 1 - 16
Sepsis, an exaggerated systemic inflammatory response, remains a major medical challenge. Both hyperinflammation and immunosuppression are implicated as causes... 
ACTIVATION | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTOXIN TOLERANCE | IN-VIVO | BIOLOGY | SEPTIC SHOCK | RECEPTOR | INTERLEUKIN-12 | DIMERIZATION | MICE | MECHANISMS | Antibodies, Neutralizing - administration & dosage | Receptors, Glucocorticoid - antagonists & inhibitors | Spleen - immunology | Dendritic Cells - immunology | Dendritic Cells - pathology | Male | Shock, Septic - prevention & control | Receptors, Glucocorticoid - metabolism | Spleen - drug effects | Shock, Septic - immunology | Shock, Septic - metabolism | Receptors, Glucocorticoid - agonists | CD11c Antigen - metabolism | Dose-Response Relationship, Drug | Interleukin-12 - blood | CD11c Antigen - genetics | Glucocorticoids - metabolism | Antibodies, Neutralizing - therapeutic use | Interleukin-12 - antagonists & inhibitors | Dendritic Cells - drug effects | Female | Spleen - pathology | Dendritic Cells - metabolism | Shock, Septic - pathology | Lipopolysaccharides - toxicity | Specific Pathogen-Free Organisms | Immunity, Innate - drug effects | Mice, Inbred C57BL | Cells, Cultured | Glucocorticoids - blood | Mice, Transgenic | Interleukin-12 - metabolism | Mice, Knockout | Animals | Glucocorticoids - antagonists & inhibitors | Signal Transduction - drug effects | Spleen - metabolism | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - administration & dosage | Receptors, Glucocorticoid - genetics | Glucocorticoids - agonists | Crosses, Genetic | Care and treatment | Corticosteroids | Immunotherapy | Septic shock | Research | Health aspects | Risk factors | Medical research | Flow cytometry | Statistical analysis | Cytokines | Dendritic cells | Rodents | Mortality | Sepsis | Software | Inflammation | Experiments
Journal Article
British journal of pharmacology, ISSN 0007-1188, 02/2014, Volume 171, Issue 3, pp. 735 - 745
Background and Purpose The COX‐2/PGE2 pathway in hypoxic cancer cells has important implications for stimulation of inflammation and tumourigenesis. However,... 
hypoxia | glucocorticoid receptor | hypoxia‐inducible factor‐1 | cyclooxygenase‐2 | glucocorticoid‐induced leucine zipper | glucocorticoid-induced leucine zipper | cyclooxygenase-2 | hypoxia-inducible factor-1 | DEXAMETHASONE | PROTEIN | ACETYLATION | RECEPTOR | FACTOR-KAPPA-B | FACTOR-I | CANCER | INHIBITION | GENE | PHARMACOLOGY & PHARMACY | Dexamethasone - antagonists & inhibitors | Receptors, Glucocorticoid - antagonists & inhibitors | Humans | Hypoxia-Inducible Factor 1, alpha Subunit - antagonists & inhibitors | Receptors, Glucocorticoid - metabolism | Alveolar Epithelial Cells - immunology | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Receptors, Glucocorticoid - agonists | Cell Hypoxia | Anti-Inflammatory Agents, Non-Steroidal - antagonists & inhibitors | Dexamethasone - pharmacology | RNA Interference | Cyclooxygenase 2 - genetics | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Cell Line | Cyclooxygenase 2 - chemistry | Transcription Factors - antagonists & inhibitors | Alveolar Epithelial Cells - metabolism | Alveolar Epithelial Cells - drug effects | Transcription Factors - genetics | Hormone Antagonists - pharmacology | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Cell Movement - drug effects | Animals | Glucocorticoids - antagonists & inhibitors | Signal Transduction - drug effects | Cyclooxygenase 2 - metabolism | Glucocorticoids - pharmacology | Genes, Reporter - drug effects | Mice | Transcription Factors - agonists | Signal transduction | Dexamethasone | Glucocorticoids | Therapeutic applications | Invasiveness | Prostaglandin E2 | Hypoxia | mRNA | Glucocorticoid receptors | Leucine zipper proteins
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 10/2013, Volume 110, Issue 42, pp. 17035 - 17040
Journal Article