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PloS one, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, pp. e54442 - e54442
Sodium/glucose cotransporter 2 (SGLT2) inhibitors are oral hypoglycemic agents used to treat patients with diabetes mellitus. SGLT2 inhibitors block... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Diabetes Mellitus - pathology | Epithelial Cells - metabolism | Gene Expression - drug effects | Diabetes Mellitus - genetics | Transcription Factor AP-1 - genetics | Epithelial Cells - drug effects | Humans | Diabetic Nephropathies - drug therapy | NF-kappa B - metabolism | Smad3 Protein - metabolism | Transcription Factor AP-1 - metabolism | Sodium-Glucose Transporter 1 - genetics | Smad3 Protein - genetics | Sodium-Glucose Transporter 1 - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Transforming Growth Factor beta1 - pharmacology | Sodium-Glucose Transporter 2 - genetics | Collagen Type IV - metabolism | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Promoter Regions, Genetic | Diabetic Nephropathies - pathology | Glucosides - pharmacology | Kidney Tubules, Proximal - pathology | Interleukin-6 - genetics | Sodium-Glucose Transporter 2 - metabolism | Diabetic Nephropathies - metabolism | Diabetes Mellitus - drug therapy | Diabetes Mellitus - metabolism | Toll-Like Receptor 4 - genetics | Diabetic Nephropathies - genetics | Epithelial Cells - pathology | Glucose - pharmacology | Toll-Like Receptor 4 - metabolism | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hypoglycemic Agents - pharmacology | NF-kappa B - genetics | Kidney Tubules, Proximal - metabolism | Collagen Type IV - genetics | Protein Binding | Benzhydryl Compounds - pharmacology | Kidney Tubules, Proximal - drug effects | Physiological aspects | Care and treatment | Genetic aspects | Research | Transforming growth factors | Diabetic nephropathies | Chromatin | Immunoprecipitation | Transforming growth factor-b | Interleukin | Clinical trials | Systematic review | Smad3 protein | Glucose | Kinases | Interleukin 6 | Proteins | Hyperglycemia | Rodents | Toll-like receptors | Collagen (type IV) | Hypoglycemic agents | Inhibition | Growth factors | Deoxyribonucleic acid--DNA | Immune system | Binding | Glucose transporter | Medical research | NF-κB protein | Diabetes mellitus | Markers | Activator protein 1 | Blocking | Reabsorption | Inflammation | Gene expression | Glucose transport | Medicine | High mobility group proteins | Hospitals | Inhibitors | Nephropathy | Sodium | Fibrosis | Kidney diseases | Diabetes | Transporter | Adenosine triphosphatase | Kidney transplantation | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Planta Medica, ISSN 0032-0943, 08/2017, Volume 83, Issue 12/13, pp. 985 - 993
Journal Article
PloS one, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e30555 - e30555
Background: Canagliflozin is a sodium glucose co-transporter (SGLT) 2 inhibitor in clinical development for the treatment of type 2 diabetes mellitus (T2DM).... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Thiophenes - therapeutic use | Diabetes Mellitus, Experimental - drug therapy | Humans | Body Weight - drug effects | Male | Muscle, Skeletal - metabolism | Muscle, Skeletal - cytology | Hyperglycemia - drug therapy | Sodium-Glucose Transporter 1 - genetics | Muscle, Skeletal - drug effects | Hyperglycemia - pathology | Sodium-Glucose Transport Proteins - metabolism | Glucosides - therapeutic use | Weight Gain - drug effects | Sodium-Glucose Transporter 1 - metabolism | Diabetes Mellitus, Experimental - metabolism | Kidney - physiopathology | Sodium-Glucose Transport Proteins - genetics | CHO Cells | Sodium-Glucose Transporter 2 - genetics | Cricetinae | Glucose Tolerance Test | Kidney - drug effects | Sodium-Glucose Transporter 2 - metabolism | Mice, Inbred C57BL | Cells, Cultured | Rats | Sodium-Glucose Transporter 2 - antagonists & inhibitors | Hyperglycemia - metabolism | Rats, Zucker | Animals | Canagliflozin | Diabetes Mellitus, Experimental - pathology | Mice, Obese | Mice | Blood Glucose - metabolism | Type 2 diabetes | Glucose metabolism | Obesity | Blood sugar | Analysis | Body weight | Glycosylated hemoglobin | Diabetes therapy | Cell culture | Animal models | Renal function | Laboratories | Liver | Homeostasis | Fuel consumption | Diabetic neuropathy | Glucose | Oocytes | Hyperglycemia | Rodents | Hemoglobin | Glucose transporter | Excretion | Kidneys | Secretion | Research & development--R&D | Diabetes mellitus | Pharmacology | Insulin | Body weight gain | Myoblasts | Beta cells | Sodium | Weight reduction | Insulin resistance | Diabetes | Mutation | Transporter | Kidney transplantation | Pharmaceuticals | Index Medicus | Research & development | R&D
Journal Article
Cardiovascular diabetology, ISSN 1475-2840, 02/2019, Volume 18, Issue 1, pp. 20 - 20
Sotagliflozin is a dual sodium-glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the treatment of both type 1 (T1D) and type 2 diabetes (T2D).... 
Cardiac & Cardiovascular Systems | Endocrinology & Metabolism | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Sodium-Glucose Transporter 1 - antagonists & inhibitors | Sodium-Glucose Transporter 2 Inhibitors - therapeutic use | Sodium-Glucose Transporter 2 - drug effects | Kidney - drug effects | Sodium-Glucose Transporter 2 Inhibitors - adverse effects | Sodium-Glucose Transporter 2 - metabolism | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Humans | Treatment Outcome | Biomarkers - blood | Diabetes Mellitus, Type 1 - drug therapy | Blood Glucose - drug effects | Diabetes Mellitus, Type 1 - diagnosis | Diabetes Mellitus, Type 2 - diagnosis | Diabetes Mellitus, Type 2 - blood | Kidney - metabolism | Animals | Diabetes Mellitus, Type 1 - blood | Glycosides - adverse effects | Sodium-Glucose Transporter 1 - metabolism | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Drug Therapy, Combination | Glycosides - therapeutic use | Glucose transporter | Urine | Medical research | Excretion | Kidneys | Peptides | Diabetes mellitus | Clinical trials | Systematic review | Diabetes mellitus (insulin dependent) | Glucose | Insulin | Small intestine | Optimization | Infusion | Inhibitors | Sodium | Intestine | Hemoglobin | Blood pressure | Adults | Diabetes | Diabetes mellitus (non-insulin dependent) | Transporter | Index Medicus | Hypoglycemic therapy | SGLT2 inhibitors
Journal Article
Nature (London), ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 397 - 401
Journal Article
Journal Article
European Journal of Heart Failure, ISSN 1388-9842, 2/2010, Volume 12, Issue 2, pp. 106 - 113
Journal Article